Diazepam binding inhibitor overexpression in mice causes hydrocephalus, decreases plasticity in excitatory synapses and impairs hippocampus-dependent learning

Molecular and Cellular Neuroscience

Volumn 34, Issue 2, 2007, Pages 199-208

  Siiskonen, Hanna ^a   Oikari, Sanna ^a   Korhonen, Veli Pekka ^a   Pitkänen, Asla ^a   Voikar, Vootele ^b   Kettunen, Mikko ^a   Hakumäki, Juhana ^a   Wahlfors, Tiina ^a   Pussinen, Raimo ^a   Penttonen, Markku ^a   Kiehne, Karlheinz ^c   Kaasinen, Selma K ^a   Alhonen, Leena ^a   Jänne, Juhani ^a   Herzig, Karl Heinz ^a,c,d,e  

^a UNIVERSITY OF EASTERN FINLAND   (Finland)

^b UNIVERSITY OF HELSINKI   (Finland)

^c UNIVERSITY HOSPITAL SCHLESWIG HOLSTEIN   (Germany)

^d KUOPIO UNIVERSITY HOSPITAL   (Finland)

^e UNIVERSITY OF OULU   (Finland)

Author keywords

[No Author keywords available]

Indexed keywords

4 AMINOBUTYRIC ACID; DIAZEPAM BINDING INHIBITOR;

ANIMAL EXPERIMENT; ARTICLE; BEHAVIOR THEORY; CONTROLLED STUDY; DENTATE GYRUS; EXCITATORY POSTSYNAPTIC POTENTIAL; EXPLORATORY BEHAVIOR; FEMALE; GENE OVEREXPRESSION; GLIA CELL; HIPPOCAMPUS; HYDROCEPHALUS; IMMUNOHISTOCHEMISTRY; LEARNING; MALE; MEMORY; MOTOR ACTIVITY; MOUSE; NERVE CELL PLASTICITY; NONHUMAN; NUCLEOTIDE SEQUENCE; PHYSIOLOGY; PRIORITY JOURNAL; PROTEIN EXPRESSION; SYNAPTIC POTENTIAL; SYNAPTIC TRANSMISSION; TRANSGENIC ANIMAL; TRANSGENIC MOUSE;

ANIMALS; AVOIDANCE LEARNING; BEHAVIOR, ANIMAL; DIAZEPAM BINDING INHIBITOR; FEMALE; HIPPOCAMPUS; HYDROCEPHALUS; LEARNING DISORDERS; LONG-TERM POTENTIATION; MAGNETIC RESONANCE IMAGING; MALE; MICE; MICE, TRANSGENIC; PHOSPHOPYRUVATE HYDRATASE; REACTION TIME; SYNAPTIC TRANSMISSION;

ANIMALIA; MUS; MUS MUSCULUS;

EID: 33846383115     PISSN: 10447431     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.mcn.2006.10.013     Document Type: Article

References (45)

1. Alho H., Costa E., Ferrero P., Fujimoto M., Cosenza-Murphy D., and Guidotti A. Diazepam-binding inhibitor: a neuropeptide located in selected neuronal populations of rat brain. Science 229 (1985) 179-182
2. Barbaccia M.L., Costa E., Ferrero P., Guidotti A., Roy A., Sunderland T., Pickar D., Paul S.M., and Goodwin F.K. A brain neuropeptide present in human spinal fluid: studies in depression, schizophrenia, and Alzheimer's disease. Arch. Gen. Psychiatry 43 (1986) 1143-1147
3. Ben-Ari Y. Limbic seizure and brain damage produced by kainic acid: mechanisms and relevance to human temporal lobe epilepsy. Neuroscience 14 (1985) 375-403
4. Berkovich A., McPhie P., Campagnone M., Guidotti A., and Hensley P. A natural processing product of rat diazepam binding inhibitor, triakontatetraneuropeptide (diazepam binding inhibitor 17-50) contains an alpha-helix, which allows discrimination between benzodiazepine binding site subtypes. Mol. Pharmacol. 37 (1990) 164-172
5. B receptor subtypes. Trends Neurosci. 11 (1988) 112-116
6. Cendes F., Cook M.J., Watson C., Andermann F., Fish D.R., Shorvon S.D., Bergin P., Free S., Dubeau F., and Arnold D.L. Frequency and characteristics of dual pathology in patients with lesional epilepsy. Neurology 45 (1995) 2058-2064
7. Clarke V.R., Ballyk B.A., Hoo K.H., Mandelzys A., Pellizzari A., Bath C.P., Thomas J., Sharpe E.F., Davies C.H., Ornstein P.L., Schoepp D.D., Kamboj R.K., Collingridge G.L., Lodge D., and Bleakman D. A hippocampal GluR5 kainate receptor regulating inhibitory synaptic transmission. Nature 389 (1997) 599-603
8. Costa E., and Guidotti A. Diazepam binding inhibitor (DBI): a peptide with multiple biological actions. Life Sci. 49 (1991) 325-344
9. Crews L., Wyss-Coray T., and Masliah E. Insights into the pathogenesis of hydrocephalus from transgenic and experimental animal models. Brain Pathol. 14 (2004) 312-316
10. Faergemann N., and Knudsen J. Role of long-chain fatty acyl-CoA esters in the regulation of metabolism and cell signaling. Biochem. J. 323 (1997) 1-12
11. Ferrarese C., Alho H., Guidotti A., and Costa E. Co-localization and co-release of GABA and putative allosteric modulators of GABA receptor. Neuropharmacology 26 (1987) 1011-1018
12. Ferrarese C., Appollonio I., Frigo M., Piolti R., Tamma F., and Frattola L. Distribution of a putative endogenous modulator of the GABAergic system in human brain. Neurology 39 (1989) 443-445
13. Ferrarese C., Appollonio I., Frigo M., Meregalli S., Piolti R., Tamma F., and Frattola L. Cerebrospinal fluid levels of diazepam-binding inhibitor in neurodegenerative disorders with dementia. Neurology 40 (1990) 632-635
14. Ferrarese C., Cogliati T., Tortorella R., Zucca C., Bogliun G., Beghi E., Passoni D., Zoia C., Begni B., Airoldi L., Alho H., and Frattola L. Diazepam binding inhibitor (DBI) in the plasma of pediatric and adult epileptic patients. Epilepsy Res. 29 (1998) 129-134
15. Ferrero P., Santi M.R., Conti-Tronconi B., Costa E., and Guidotti A. Study of an octadecaneuropeptide derived from diazepam binding inhibitor (DBI): biological activity and presence in rat brain. Proc. Natl. Acad. Sci. U. S. A. 83 (1986) 827-831
16. Ferrero P., Benna P., Costa P., Tarenzi L., Baggio G., Bergamasco B., and Bergamini L. Diazepam binding inhibitor-like immunoreactivity (DBI-LI) in human CSF. Correlations with neurological disorders. J. Neurol. Sci. 87 (1988) 327-349
17. Garcia de Mateos-Verchere J., Leprince J., Tonon M.C., Vaudry H., and Costentin J. Reduction of pentylenetetrazol-induced convulsions by the octadecaneuropeptide ODN. Peptides 20 (1999) 1431-1436
18. Giguere J.F., Lavoie J., Tonon M.C., Désy L., Laudry H., Pelletier G., and Butterworth R.F. Astrocytic benzodiazepine receptors and their endogenous ligands in hepatic encephalopathy. Abstr.-Soc. Neurosci. 16 (1990) 908
19. Gomes F.C., Sousa V.d.O., and Romao L. Emerging roles for TGF-beta1 in nervous system development. Int. J. Dev. Neurosci. 23 (2005) 413-424
20. Guidotti A., Forchetti C., Corda M., Konkel D., Bennet C., and Costa E. Isolation, characterization, and purification to homogeneity of an endogenous polypeptide with agonistic action on benzodiazepine receptors. Proc. Natl. Acad. Sci. U. S. A. 80 (1983) 3531-3535
21. Helledie T., Grontved L., Jensen S.S., Kiilerich P., Rietveld L., Albrektsen T., Boysen M.S., Nohr J., Larsen L.K., Fleckner J., Stunnenberg H.G., Kristiansen K., and Mandrup S. The gene encoding the Acyl-CoA-binding protein is activated by peroxisome proliferator-activated receptor gamma through an intronic response element functionally conserved between humans and rodents. J. Biol. Chem. 277 (2002) 26821-26830
22. Israel D.I. A PCR-based method for high stringency screening of DNA libraries. Nucleic Acids Res. 21 (1993) 2627-2631
23. Katsura M., Ohkuma S., Tsujimura A., and Kuriyama K. Increase of diazepam binding inhibitor mRNA levels in the brains of chronically ethanol-treated and -withdrawn mice. J. Pharmacol. Exp. Ther. 273 (1995) 1529-1533
24. Katsura M., Hara A., Higo A., Tarumi C., Hibino Y., and Ohkuma S. Continuous treatment with morphine increases diazepam binding inhibitor mRNA in mouse brain. J. Neurochem. 71 (1998) 2638-2641
25. Katsura M., Ohkuma S., Tsujimura A., Xu J., Hibino Y., Ishikawa E., and Kuriyama K. Functional involvement of benzodiazepine receptors in ethanol-induced increases of diazepam binding inhibitor (DBI) and its mRNA in the mouse brain. Brain Res. Mol. Brain Res. 54 (1998) 124-132
26. Katsura M., Ohkuma S., Xu J., Hibino Y., Tsujimura A., and Kuriyama K. Continuous treatment with nicotine increases diazepam binding inhibitor (DBI) and its mRNA in the mouse brain. Brain Res. Mol. Brain Res. 55 (1998) 345-349
27. Katsura M., Takesue M., Shuto K., Mohri Y., Tarumi C., Tsujimura A., Shirotani K., and Ohkuma S. NMDA receptor activation enhances diazepam binding inhibitor and its mRNA expressions in mouse cerebral cortical neurons. Brain Res. Mol. Brain Res. 88 (2001) 161-165
28. Kavaliers M., and Hirst M. An octadecaneuropeptide (ODN) derived from diazepam binding inhibitor increases aggressive interactions in mice. Brain Res. 383 (1986) 343-349
29. Lahteinen S., Pitkanen A., Koponen E., Saarelainen T., and Castren E. Exacerbated status epilepticus and acute cell loss, but no changes in epileptogenesis, in mice with increased brain-derived neurotrophic factor signaling. Neuroscience 122 (2003) 1081-1092
30. Larson J., and Lynch G. Induction of synaptic potentiation in hippocampus by patterned stimulation involves two events. Science 232 (1986) 985-988
31. Larson J., and Lynch G. Role of N-methyl-d-aspartate receptors in the induction of synaptic potentiation by burst stimulation patterned after the hippocampal theta-rhythm. Brain Res. 441 (1988) 111-118
32. Lewis D.A., Campbell M.J., and Morrison J.H. An immunohistochemical characterization of somatostatin-28 and somatostatin-281-12 in monkey prefrontal cortex. J. Comp. Neurol. 248 (1986) 1-18
33. Michaelis E.K. Molecular biology of glutamate receptors in the central nervous system and their role in excitotoxicity, oxidative stress and aging. Prog. Neurobiol. 54 (1998) 369-415
34. Morris R.G. Spatial localization does not require the presence of local cues. Learn. Motiv. 12 (1981) 239-260
35. Nadler J.V. Minireview. Kainic acid as a tool for the study of temporal lobe epilepsy. Life Sci. 29 (1981) 2031-2042
36. Nitz I., Doring F., Schrezenmeir J., and Burwinkel B. Identification of new acyl-CoA binding protein transcripts in human and mouse. Int. J. Biochem. Cell Biol. 37 (2005) 2395-2405
37. Pussinen R., and Sirvio J. Minor role for alpha1-adrenoceptors in the facilitation of induction and early maintenance of long-term potentiation in the CA1 field of the hippocampus. J. Neurosci. Res. 51 (1998) 309-315
38. Racine R.J. Modification of seizure activity by electrical stimulation: II. Motor seizure. Electroencephalogr. Clin. Neurophysiol. 32 (1972) 281-294
39. Rodriguez-Moreno A., Herreras O., and Lerma J. Kainate receptors presynaptically downregulate GABAergic inhibition in the rat hippocampus. Neuron 19 (1997) 893-901
40. Schmittgen T.D., and Zakrajsek B.A. Effect of experimental treatment on housekeeping gene expression: validation by real-time, quantitative RT-PCR. J. Biochem. Biophys. Methods 46 (2000) 69-81
41. Slobodyansky E., Guidotti A., Wambebe C., Berkovich A., and Costa E. Isolation and characterization of a rat brain triakontatetraneuropeptide, a posttranslational product of diazepam binding inhibitor: specific action at the Ro 5-4864 recognition site. J. Neurochem. 53 (1989) 1276-1284
42. Tokay T., Masmoudi O., Gandolfo P., Leprince J., Pelletier G., Vaudry H., and Tonon M.C. Beta-amyloid peptides stimulate endozepine biosynthesis in cultured rat astrocytes. J. Neurochem. 94 (2005) 607-616
43. Vezzani A., Serafini R., Stasi M.A., Samanin R., and Ferrarese C. Epileptogenic activity of two peptides derived from diazepam binding inhibitor after intrahippocampal injection in rats. Epilepsia 32 (1991) 597-603
44. Voikar V., Vasar E., and Rauvala H. Behavioral alterations induced by repeated testing in C57BL/6J and 129S2/Sv mice: implications for phenotyping screens. Genes Brain Behav. 3 (2004) 27-38
45. Yanase H., Shimizu H., Yamada K., and Iwanaga T. Cellular localization of the diazepam binding inhibitor in glial cells with special reference to its coexistence with brain-type fatty acid binding protein. Arch. Histol. Cytol. 65 (2002) 27-36