The inhibitory effect of the fungicides captan and captafol on eukaryotic topoisomerases in vitro and lack of recombinagenic activity in the wing spot test of Drosophila melanogaster

Mutation Research - Genetic Toxicology and Environmental Mutagenesis

Volumn 518, Issue 2, 2002, Pages 205-213

  Rahden Staron, Iwonna ^a  

^a MEDICAL UNIVERSITY OF WARSAW   (Poland)

Author keywords

Captafol; Captan; Drosophila melanogaster; Genotoxicity; SMART; Topoisomerases I and II

Indexed keywords

CAPTAFOL; CAPTAN; DNA TOPOISOMERASE; DNA TOPOISOMERASE (ATP HYDROLYSING); FUNGICIDE; CYCLOHEXENE DERIVATIVE; DRUG DERIVATIVE; ENZYME INHIBITOR; MUTAGENIC AGENT;

ANIMAL CELL; ANIMAL EXPERIMENT; ARTICLE; CONTROLLED STUDY; DROSOPHILA MELANOGASTER; ENZYME ACTIVITY; ENZYME INHIBITION; EUKARYOTE; FEEDING; FORELIMB; GENOTOXICITY; IN VITRO STUDY; IN VIVO STUDY; INHIBITION KINETICS; LARVA; MITOTIC RECOMBINATION; MOUSE; NONHUMAN; PRIORITY JOURNAL; SOMATIC MUTATION; ANIMAL; CROSS BREEDING; DOSE RESPONSE; DRUG ANTAGONISM; DRUG EFFECT; ENZYMOLOGY; FEMALE; GENETIC RECOMBINATION; GENETICS; LEUKEMIA L 5178 Y; MALE; METABOLISM; METHODOLOGY; MUTAGEN TESTING;

DROSOPHILA MELANOGASTER; EUKARYOTA;

ANIMALS; CAPTAN; CROSSES, GENETIC; CYCLOHEXENES; DNA TOPOISOMERASES, TYPE I, EUKARYOTIC; DNA TOPOISOMERASES, TYPE II, EUKARYOTIC; DOSE-RESPONSE RELATIONSHIP, DRUG; DROSOPHILA MELANOGASTER; ENZYME INHIBITORS; FEMALE; FUNGICIDES, INDUSTRIAL; LEUKEMIA L5178; MALE; MUTAGENICITY TESTS; MUTAGENS; RECOMBINATION, GENETIC; WING;

EID: 33846353817     PISSN: 13835718     EISSN: None     Source Type: Journal    
DOI: 10.1016/S1383-5718(02)00107-9     Document Type: Article

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