메뉴 건너뛰기




Volumn 25, Issue 3, 2007, Pages 309-316

Neurokinin-1 receptor antagonism in a human model of visceral hypersensitivity

Author keywords

[No Author keywords available]

Indexed keywords

HYDROCHLORIC ACID; NEUROKININ 1 RECEPTOR; NEUROKININ 1 RECEPTOR ANTAGONIST; PLACEBO; SUBSTANCE P;

EID: 33846334419     PISSN: 02692813     EISSN: 13652036     Source Type: Journal    
DOI: 10.1111/j.1365-2036.2006.03190.x     Document Type: Article
Times cited : (21)

References (40)
  • 1
    • 0025104302 scopus 로고
    • Release of immunoreactive Substance P in the spinal cord during development of acute arthritis in the knee joint of the cat: A study with antibody microprobes
    • Schaible HG, Jarrott B, Hope PJ, Duggan AW. Release of immunoreactive Substance P in the spinal cord during development of acute arthritis in the knee joint of the cat: a study with antibody microprobes. Brain Res 1990; 529: 214-23.
    • (1990) Brain Res , vol.529 , pp. 214-223
    • Schaible, H.G.1    Jarrott, B.2    Hope, P.J.3    Duggan, A.W.4
  • 2
    • 0034036363 scopus 로고    scopus 로고
    • Deficits in visceral pain and hyperalgesia of mice with a disruption of the tachykinin NK1 receptor gene
    • Laird JMA, Olivar T, Roza C, De Felipe C, Hunt SP, Cervero F. Deficits in visceral pain and hyperalgesia of mice with a disruption of the tachykinin NK1 receptor gene. Neuroscience 2000; 98: 345-52.
    • (2000) Neuroscience , vol.98 , pp. 345-352
    • Laird, J.M.A.1    Olivar, T.2    Roza, C.3    De Felipe, C.4    Hunt, S.P.5    Cervero, F.6
  • 3
    • 0036179293 scopus 로고    scopus 로고
    • Acute restraint stress activates functional NK1 receptor in the colon of female rats: Involvement of steroids
    • Bradesi S, Eutamene H, Fioramonti J, Bueno L. Acute restraint stress activates functional NK1 receptor in the colon of female rats: involvement of steroids. Gut 2002; 50: 349-54.
    • (2002) Gut , vol.50 , pp. 349-354
    • Bradesi, S.1    Eutamene, H.2    Fioramonti, J.3    Bueno, L.4
  • 4
    • 0025813385 scopus 로고
    • Responses of functionally identified neurones in the dorsal horn of the cat spinal cord to Substance P, neurokinin A and physalaemin
    • Salter MW, Henry JL. Responses of functionally identified neurones in the dorsal horn of the cat spinal cord to Substance P, neurokinin A and physalaemin. Neuroscience 1991; 43: 601-10.
    • (1991) Neuroscience , vol.43 , pp. 601-610
    • Salter, M.W.1    Henry, J.L.2
  • 5
    • 0033197997 scopus 로고    scopus 로고
    • Spinal Substance P receptor expression and internalization in acute, short-term, and long-term inflammatory pain states
    • Honore P, Menning PM, Rogers SD, et al. Spinal Substance P receptor expression and internalization in acute, short-term, and long-term inflammatory pain states. J Neurosci 1999; 19: 7670-8.
    • (1999) J Neurosci , vol.19 , pp. 7670-7678
    • Honore, P.1    Menning, P.M.2    Rogers, S.D.3
  • 6
    • 0029655582 scopus 로고    scopus 로고
    • Spinal cord Substance P receptor immunoreactivity increases in both inflammatory and nerve injury models of persistent pain
    • Abbadie C, Brown JL, Mantyh PW, Basbaum AI. Spinal cord Substance P receptor immunoreactivity increases in both inflammatory and nerve injury models of persistent pain. Neuroscience 1996; 70: 201-9.
    • (1996) Neuroscience , vol.70 , pp. 201-209
    • Abbadie, C.1    Brown, J.L.2    Mantyh, P.W.3    Basbaum, A.I.4
  • 8
    • 0030764290 scopus 로고    scopus 로고
    • Inhibition of hyperalgesia by ablation of lamina I spinal neurons expressing the Substance P receptor
    • Mantyh PW, Rogers SD, Honore P, et al. Inhibition of hyperalgesia by ablation of lamina I spinal neurons expressing the Substance P receptor. Science 1997; 278: 275-9.
    • (1997) Science , vol.278 , pp. 275-279
    • Mantyh, P.W.1    Rogers, S.D.2    Honore, P.3
  • 9
    • 0032568444 scopus 로고    scopus 로고
    • Altered nociception, analgesia and aggression in mice lacking the receptor for Substance P
    • De Felipe C, Herrero JF, O'Brien JA, et al. Altered nociception, analgesia and aggression in mice lacking the receptor for Substance P. Nature 1998; 392: 394-7.
    • (1998) Nature , vol.392 , pp. 394-397
    • De Felipe, C.1    Herrero, J.F.2    O'Brien, J.A.3
  • 10
    • 0032478311 scopus 로고    scopus 로고
    • Hypoalgesia in mice with a targeted deletion of the tachykinin 1 gene
    • Zimmer A, Zimmer AM, Baffi J, et al. Hypoalgesia in mice with a targeted deletion of the tachykinin 1 gene. Proc Natl Acad Sci U S A 1998; 95: 2630-5.
    • (1998) Proc Natl Acad Sci U S A , vol.95 , pp. 2630-2635
    • Zimmer, A.1    Zimmer, A.M.2    Baffi, J.3
  • 11
    • 0026610996 scopus 로고
    • The non-peptide NK1 receptor antagonist, (+/-)-CP-96,345, produces antinociceptive and anti-oedema effects in the rat
    • Birch PJ, Harrison SM, Hayes AG, Rogers H, Tyers MB. The non-peptide NK1 receptor antagonist, (+/-)-CP-96,345, produces antinociceptive and anti-oedema effects in the rat. Br J Pharmacol 1992; 105: 508-10.
    • (1992) Br J Pharmacol , vol.105 , pp. 508-510
    • Birch, P.J.1    Harrison, S.M.2    Hayes, A.G.3    Rogers, H.4    Tyers, M.B.5
  • 12
    • 12344296557 scopus 로고    scopus 로고
    • A tachykinin NK1 receptor antagonist attenuates the 4 beta-phorbol-12-myristate-13-acetate-induced nociceptive behaviour in the rat
    • Tsuchiya M, Sakakibara A, Yamamoto M. A tachykinin NK1 receptor antagonist attenuates the 4 beta-phorbol-12-myristate-13-acetate-induced nociceptive behaviour in the rat. Eur J Pharmacol 2005; 507: 29-34.
    • (2005) Eur J Pharmacol , vol.507 , pp. 29-34
    • Tsuchiya, M.1    Sakakibara, A.2    Yamamoto, M.3
  • 13
    • 0034807739 scopus 로고    scopus 로고
    • Combinations of neurokinin receptor antagonists reduce visceral hyperalgesia
    • Kamp EH, Beck DR, Gebhart GF. Combinations of neurokinin receptor antagonists reduce visceral hyperalgesia. J Pharmacol Exp Ther 2001; 299: 105-13.
    • (2001) J Pharmacol Exp Ther , vol.299 , pp. 105-113
    • Kamp, E.H.1    Beck, D.R.2    Gebhart, G.F.3
  • 14
    • 0036008323 scopus 로고    scopus 로고
    • Effects of tachykinin NK1 receptor antagonists on the viscerosensory response caused by colorectal distention in rabbits
    • Okano S, Ikeura Y, Inatomi N. Effects of tachykinin NK1 receptor antagonists on the viscerosensory response caused by colorectal distention in rabbits. J Pharmacol Exp Ther 2002; 300: 925-31.
    • (2002) J Pharmacol Exp Ther , vol.300 , pp. 925-931
    • Okano, S.1    Ikeura, Y.2    Inatomi, N.3
  • 16
    • 0142165222 scopus 로고    scopus 로고
    • Role of tachykinin NK1, NK2 and NK3 receptors in the modulation of visceral hypersensitivity in the rat
    • Gaudreau G-A, Plourde V. Role of tachykinin NK1, NK2 and NK3 receptors in the modulation of visceral hypersensitivity in the rat. Neurosci Lett 2003; 351: 59-62.
    • (2003) Neurosci Lett , vol.351 , pp. 59-62
    • Gaudreau, G.-A.1    Plourde, V.2
  • 17
    • 0344837295 scopus 로고    scopus 로고
    • Stress-induced visceral hypersensitivity in female rats is estrogen-dependent and involves tachykinin NK1 receptors
    • Bradesi S, Eutamene H, Garcia-Villar R, Fioramonti J, Bueno L. Stress-induced visceral hypersensitivity in female rats is estrogen-dependent and involves tachykinin NK1 receptors. Pain 2003; 102: 227-34.
    • (2003) Pain , vol.102 , pp. 227-234
    • Bradesi, S.1    Eutamene, H.2    Garcia-Villar, R.3    Fioramonti, J.4    Bueno, L.5
  • 18
    • 0034214841 scopus 로고    scopus 로고
    • NK1 (Substance P) receptor antagonists - why are they not analgesic in humans?
    • Hill R. NK1 (Substance P) receptor antagonists - why are they not analgesic in humans? Trends Pharmacol Sci 2000; 21: 244-6.
    • (2000) Trends Pharmacol Sci , vol.21 , pp. 244-246
    • Hill, R.1
  • 19
    • 0031971830 scopus 로고    scopus 로고
    • Differences in expression of oligosaccharides, neuropeptides, carbonic anhydrase and neurofilament in rat primary afferent neurons retrogradely labelled via skin, muscle or visceral nerves
    • Perry MJ, Lawson SN. Differences in expression of oligosaccharides, neuropeptides, carbonic anhydrase and neurofilament in rat primary afferent neurons retrogradely labelled via skin, muscle or visceral nerves. Neuroscience 1998; 85: 293-310.
    • (1998) Neuroscience , vol.85 , pp. 293-310
    • Perry, M.J.1    Lawson, S.N.2
  • 20
    • 0028999428 scopus 로고
    • Morphological characterization of Substance P receptor-immunoreactive neurons in the rat spinal cord and trigeminal nucleus caudalis
    • Brown JL, Liu H, Maggio JE, Vigna SR, Mantyh PW, Basbaum AI. Morphological characterization of Substance P receptor-immunoreactive neurons in the rat spinal cord and trigeminal nucleus caudalis. J Comp Neurol 1995; 356: 327-44.
    • (1995) J Comp Neurol , vol.356 , pp. 327-344
    • Brown, J.L.1    Liu, H.2    Maggio, J.E.3    Vigna, S.R.4    Mantyh, P.W.5    Basbaum, A.I.6
  • 21
    • 0034734670 scopus 로고    scopus 로고
    • Contribution of central sensitisation to the development of noncardiac chest pain
    • Sarkar S, Aziz Q, Woolf CJ, Hobson AR, Thompson DG. Contribution of central sensitisation to the development of noncardiac chest pain. Lancet 2000; 356: 1154-9.
    • (2000) Lancet , vol.356 , pp. 1154-1159
    • Sarkar, S.1    Aziz, Q.2    Woolf, C.J.3    Hobson, A.R.4    Thompson, D.G.5
  • 23
    • 1542317629 scopus 로고    scopus 로고
    • The development and maintenance of human visceral pain hypersensitivity is dependent on the N-methly-D-aspartate receptor
    • Willert RP, Woolf CJ, Hobson AR, Delaney C, Thompson DG, Aziz Q. The development and maintenance of human visceral pain hypersensitivity is dependent on the N-methly-D-aspartate receptor. Gastroenterology 2004; 126: 683-92.
    • (2004) Gastroenterology , vol.126 , pp. 683-692
    • Willert, R.P.1    Woolf, C.J.2    Hobson, A.R.3    Delaney, C.4    Thompson, D.G.5    Aziz, Q.6
  • 24
    • 0037220693 scopus 로고    scopus 로고
    • The prostaglandin E2 receptor-1 (EP-1) mediates acid-induced visceral pain hypersensitivity in humans
    • Sarkar S, Hobson AR, Hughes A, et al. The prostaglandin E2 receptor-1 (EP-1) mediates acid-induced visceral pain hypersensitivity in humans. Gastroenterology 2003; 124: 18-25.
    • (2003) Gastroenterology , vol.124 , pp. 18-25
    • Sarkar, S.1    Hobson, A.R.2    Hughes, A.3
  • 26
    • 0036830627 scopus 로고    scopus 로고
    • NMDA receptor pathways as drug targets
    • Kemp JA, McKernan RM. NMDA receptor pathways as drug targets. Nat Neurosci 2002; 5 (Suppl.): 1039-42.
    • (2002) Nat Neurosci , vol.5 , Issue.SUPPL. , pp. 1039-1042
    • Kemp, J.A.1    McKernan, R.M.2
  • 27
    • 0032846762 scopus 로고    scopus 로고
    • Disruption of the Substance P receptor (neurokinin-1) gene does not prevent upregulation of preprotachykinin-A mRNA in the spinal cord of mice following peripheral inflammation
    • Palmer JA, De Felipe C, O'Brien JA, Hunt SP. Disruption of the Substance P receptor (neurokinin-1) gene does not prevent upregulation of preprotachykinin-A mRNA in the spinal cord of mice following peripheral inflammation. Eur J Neurosci 1999; 11: 3531-8.
    • (1999) Eur J Neurosci , vol.11 , pp. 3531-3538
    • Palmer, J.A.1    De Felipe, C.2    O'Brien, J.A.3    Hunt, S.P.4
  • 28
    • 0030246892 scopus 로고    scopus 로고
    • The spinal contribution of Substance P to the generation and maintenance of inflammatory hyperalgesia in the rat
    • Traub RJ. The spinal contribution of Substance P to the generation and maintenance of inflammatory hyperalgesia in the rat. Pain 1996; 67: 151-61.
    • (1996) Pain , vol.67 , pp. 151-161
    • Traub, R.J.1
  • 29
    • 13044305848 scopus 로고    scopus 로고
    • Transmission of chronic nociception by spinal neurons expressing the Substance P receptor
    • Nichols ML, Allen BJ, Rogers SD, et al. Transmission of chronic nociception by spinal neurons expressing the Substance P receptor. Science 1999; 286: 1558-61.
    • (1999) Science , vol.286 , pp. 1558-1561
    • Nichols, M.L.1    Allen, B.J.2    Rogers, S.D.3
  • 30
    • 0035252574 scopus 로고    scopus 로고
    • Role of central and peripheral tachykinin NK1 receptors in capsaicin-induced pain and hyperalgesia in mice
    • Laird JMA, Roza C, De Felipe C, Hunt SP, Cervero F. Role of central and peripheral tachykinin NK1 receptors in capsaicin-induced pain and hyperalgesia in mice. Pain 2001; 90: 97-103.
    • (2001) Pain , vol.90 , pp. 97-103
    • Laird, J.M.A.1    Roza, C.2    De Felipe, C.3    Hunt, S.P.4    Cervero, F.5
  • 31
    • 0034926074 scopus 로고    scopus 로고
    • Effects of TAK-637, a novel neurokinin-1 receptor antagonist, on colonic function in vivo
    • Okano S, Nagaya H, Ikeura Y, Natsugari H, Inatomi N. Effects of TAK-637, a novel neurokinin-1 receptor antagonist, on colonic function in vivo. J Pharmacol Exp Ther 2001; 298: 559-64.
    • (2001) J Pharmacol Exp Ther , vol.298 , pp. 559-564
    • Okano, S.1    Nagaya, H.2    Ikeura, Y.3    Natsugari, H.4    Inatomi, N.5
  • 32
    • 0000092897 scopus 로고    scopus 로고
    • Discrepant Results from Preclinical and Clinical Studies on the Potential of Substance P Receptor Antagonist Compounds as Analgesics
    • Seattle: IASP Press
    • Boyce S, Hill R. Discrepant Results from Preclinical and Clinical Studies on the Potential of Substance P Receptor Antagonist Compounds as Analgesics. Proc 9th World Congress on Pain. Seattle: IASP Press, 2000.
    • (2000) Proc 9th World Congress on Pain
    • Boyce, S.1    Hill, R.2
  • 33
    • 0025990427 scopus 로고
    • Investigation into species variants in tachykinin NK1 receptors by use of the non-peptide antagonist, CP-96,345
    • Beresford IJ, Hagan RM, Ireland SJ. Investigation into species variants in tachykinin NK1 receptors by use of the non-peptide antagonist, CP-96,345. Br J Pharmacol 1991; 104: 292-3.
    • (1991) Br J Pharmacol , vol.104 , pp. 292-293
    • Beresford, I.J.1    Hagan, R.M.2    Ireland, S.J.3
  • 34
    • 0033410218 scopus 로고    scopus 로고
    • The Substance P antagonist L-760,735 inhibits stress-induced NK(1) receptor internalisation in the basolateral amygdala
    • Smith DW, Hewson L, Fuller P, Williams AR, Wheeldon A, Rupniak NM. The Substance P antagonist L-760,735 inhibits stress-induced NK(1) receptor internalisation in the basolateral amygdala. Brain Res 1999; 848: 90-5.
    • (1999) Brain Res , vol.848 , pp. 90-95
    • Smith, D.W.1    Hewson, L.2    Fuller, P.3    Williams, A.R.4    Wheeldon, A.5    Rupniak, N.M.6
  • 35
    • 0035852719 scopus 로고    scopus 로고
    • Genetic and pharmacological disruption of neurokinin 1 receptor function decreases anxiety-related behaviors and increases serotonergic function
    • Santarelli L, Gobbi G, Debs PC, et al. Genetic and pharmacological disruption of neurokinin 1 receptor function decreases anxiety-related behaviors and increases serotonergic function. Proc Natl Acad Sci U S A 2001; 98: 1912-7.
    • (2001) Proc Natl Acad Sci U S A , vol.98 , pp. 1912-1917
    • Santarelli, L.1    Gobbi, G.2    Debs, P.C.3
  • 36
    • 33846301791 scopus 로고    scopus 로고
    • PET imaging of NK-1 receptors in living human brain
    • Hietala J. PET imaging of NK-1 receptors in living human brain. Int J Neuropsychopharmacol 2000; 3: 60-62.
    • (2000) Int J Neuropsychopharmacol , vol.3 , pp. 60-62
    • Hietala, J.1
  • 37
    • 2442535179 scopus 로고    scopus 로고
    • Tachykinin NK2 receptor antagonists for the treatment of irritable bowel syndrome
    • Lecci A, Capriati A, Maggi CA. Tachykinin NK2 receptor antagonists for the treatment of irritable bowel syndrome. Br J Pharmacol 2004; 141: 1249-63.
    • (2004) Br J Pharmacol , vol.141 , pp. 1249-1263
    • Lecci, A.1    Capriati, A.2    Maggi, C.A.3
  • 38
    • 0025974775 scopus 로고
    • The induction and maintenance of central sensitization is dependent on N-methyl-D-aspartic acid receptor activation; implications for the treatment of post-injury pain hypersensitivity states
    • Woolf CJ, Thompson SW. The induction and maintenance of central sensitization is dependent on N-methyl-D-aspartic acid receptor activation; implications for the treatment of post-injury pain hypersensitivity states. Pain 1991; 44: 293-9.
    • (1991) Pain , vol.44 , pp. 293-299
    • Woolf, C.J.1    Thompson, S.W.2
  • 39
    • 0026552808 scopus 로고
    • Protein kinase C reduces Mg2+ block of NMDA-receptor channels as a mechanism of modulation
    • Chen L, Huang LY. Protein kinase C reduces Mg2+ block of NMDA-receptor channels as a mechanism of modulation. Nature 1992; 356: 521-3.
    • (1992) Nature , vol.356 , pp. 521-523
    • Chen, L.1    Huang, L.Y.2


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.