-
1
-
-
3042781558
-
Insulin-like growth factors and neoplasia
-
Pollak, M. N., Schernhammer, E. S. and Hankinson, S. E. (2004) Insulin-like growth factors and neoplasia. Nat. Rev. Cancer 4, 505-518
-
(2004)
Nat. Rev. Cancer
, vol.4
, pp. 505-518
-
-
Pollak, M.N.1
Schernhammer, E.S.2
Hankinson, S.E.3
-
2
-
-
0033906634
-
Structure and function of the type 1 insulin-like growth factor receptor
-
Adams, T. E., Epa, V. C., Garrett, T. P. and Ward, C. W. (2000) Structure and function of the type 1 insulin-like growth factor receptor. Cell. Mol. Life Sci. 57, 1050-1093
-
(2000)
Cell. Mol. Life Sci
, vol.57
, pp. 1050-1093
-
-
Adams, T.E.1
Epa, V.C.2
Garrett, T.P.3
Ward, C.W.4
-
3
-
-
0036782071
-
Structural biology of insulin and IGF1 receptors: Implications for drug design
-
De Meyts, P. and Whittaker, J. (2002) Structural biology of insulin and IGF1 receptors: implications for drug design. Nat. Rev. Drug Discov. 1, 769-783
-
(2002)
Nat. Rev. Drug Discov
, vol.1
, pp. 769-783
-
-
De Meyts, P.1
Whittaker, J.2
-
4
-
-
0027955344
-
Essential role of tyrosine residues 1131, 1135, and 1136 of the insulin-like growth factor-I (IGF-I) receptor in IGF-I action
-
Kato, H., Faria, T. N., Stannard, B., Roberts, Jr, C. T. and Le Roith, D. (1994) Essential role of tyrosine residues 1131, 1135, and 1136 of the insulin-like growth factor-I (IGF-I) receptor in IGF-I action. Mol. Endocrinol. 8, 40-50
-
(1994)
Mol. Endocrinol
, vol.8
, pp. 40-50
-
-
Kato, H.1
Faria, T.N.2
Stannard, B.3
Roberts Jr, C.T.4
Le Roith, D.5
-
5
-
-
0346725862
-
Regulation of IGF-I receptor signaling in tumor cells
-
O'Connor, R. (2003) Regulation of IGF-I receptor signaling in tumor cells. Horm. Metab. Res. 35, 771-777
-
(2003)
Horm. Metab. Res
, vol.35
, pp. 771-777
-
-
O'Connor, R.1
-
6
-
-
3142690018
-
Signalling by the type 1 insulin-like growth factor receptor: Interplay with the epidermal growth factor receptor
-
Adams, T. E., McKern, N. M. and Ward, C. W. (2004) Signalling by the type 1 insulin-like growth factor receptor: interplay with the epidermal growth factor receptor. Growth Factors 22, 89-95
-
(2004)
Growth Factors
, vol.22
, pp. 89-95
-
-
Adams, T.E.1
McKern, N.M.2
Ward, C.W.3
-
7
-
-
33344467985
-
Targeting insulin-like growth factor pathways
-
Yee, D. (2006) Targeting insulin-like growth factor pathways. Br. J. Cancer 94, 465-468
-
(2006)
Br. J. Cancer
, vol.94
, pp. 465-468
-
-
Yee, D.1
-
8
-
-
28544444712
-
Type I insulin-like growth factor receptor as a therapeutic target in cancer
-
Miller, B. S. and Yee, D. (2005) Type I insulin-like growth factor receptor as a therapeutic target in cancer. Cancer Res. 65, 10123-10127
-
(2005)
Cancer Res
, vol.65
, pp. 10123-10127
-
-
Miller, B.S.1
Yee, D.2
-
9
-
-
0032560753
-
Crystal structure of the first three domains of the type-1 insulin-like growth factor receptor
-
Garrett, T. P., McKern, N. M., Lou, M., Frenkel, M. J., Bentley, J. D., Lovrecz, G. O., Elleman, T. C., Cosgrove, L. J. and Ward, C. W. (1998) Crystal structure of the first three domains of the type-1 insulin-like growth factor receptor. Nature 394, 395-399
-
(1998)
Nature
, vol.394
, pp. 395-399
-
-
Garrett, T.P.1
McKern, N.M.2
Lou, M.3
Frenkel, M.J.4
Bentley, J.D.5
Lovrecz, G.O.6
Elleman, T.C.7
Cosgrove, L.J.8
Ward, C.W.9
-
10
-
-
0035941231
-
Alanine scanning mutagenesis of a type 1 insulin-like growth factor receptor ligand binding site
-
Whittaker, J., Groth, A. V., Mynarcik, D. C., Pluzek, L., Gadsboll, V. L. and Whittaker, L. J. (2001) Alanine scanning mutagenesis of a type 1 insulin-like growth factor receptor ligand binding site. J. Biol. Chem. 276, 43980-43986
-
(2001)
J. Biol. Chem
, vol.276
, pp. 43980-43986
-
-
Whittaker, J.1
Groth, A.V.2
Mynarcik, D.C.3
Pluzek, L.4
Gadsboll, V.L.5
Whittaker, L.J.6
-
11
-
-
2342551975
-
Mapping of the insulin-like growth factor II binding site of the Type I insulin-like growth factor receptor by alanine scanning mutagenesis
-
Sorensen, H., Whittaker, L., Hinrichsen, J., Groth, A. and Whittaker, J. (2004) Mapping of the insulin-like growth factor II binding site of the Type I insulin-like growth factor receptor by alanine scanning mutagenesis. FEBS Lett. 565, 19-22
-
(2004)
FEBS Lett
, vol.565
, pp. 19-22
-
-
Sorensen, H.1
Whittaker, L.2
Hinrichsen, J.3
Groth, A.4
Whittaker, J.5
-
12
-
-
0034598998
-
Properties of an insulin receptor with an IGF-1 receptor loop exchange in the cysteine-rich region
-
Hoyne, P. A., Elleman, T. C., Adams, T. E., Richards, K. M. and Ward, C. W. (2000) Properties of an insulin receptor with an IGF-1 receptor loop exchange in the cysteine-rich region. FEBS Lett. 469, 57-60
-
(2000)
FEBS Lett
, vol.469
, pp. 57-60
-
-
Hoyne, P.A.1
Elleman, T.C.2
Adams, T.E.3
Richards, K.M.4
Ward, C.W.5
-
13
-
-
0025009815
-
The cysteine-rich domains of the insulin and insulin-like growth factor I receptors are primary determinants of hormone binding specificity: Evidence from receptor chimeras
-
Gustafson, T. A. and Rutter, W. J. (1990) The cysteine-rich domains of the insulin and insulin-like growth factor I receptors are primary determinants of hormone binding specificity: evidence from receptor chimeras. J. Biol. Chem. 265, 18663-18667
-
(1990)
J. Biol. Chem
, vol.265
, pp. 18663-18667
-
-
Gustafson, T.A.1
Rutter, W.J.2
-
14
-
-
22544478497
-
Molecular interactions of the IGF system
-
Denley, A., Cosgrove, L. J., Booker, G. W., Wallace, J. C. and Forbes, B. E. (2005) Molecular interactions of the IGF system. Cytokine Growth Factor Res. 16, 421-439
-
(2005)
Cytokine Growth Factor Res
, vol.16
, pp. 421-439
-
-
Denley, A.1
Cosgrove, L.J.2
Booker, G.W.3
Wallace, J.C.4
Forbes, B.E.5
-
15
-
-
5044227353
-
Structural determinants for high-affinity binding of insulin-like growth factor II to insulin receptor (IR)-A, the exon 11 minus isoform of the IR
-
Denley, A., Bonython, E. R., Booker, G. W., Cosgrove, L. J., Forbes, B. E., Ward, C. W. and Wallace, J. C. (2004) Structural determinants for high-affinity binding of insulin-like growth factor II to insulin receptor (IR)-A, the exon 11 minus isoform of the IR. Mol. Endocrinol. 18, 2502-2512
-
(2004)
Mol. Endocrinol
, vol.18
, pp. 2502-2512
-
-
Denley, A.1
Bonython, E.R.2
Booker, G.W.3
Cosgrove, L.J.4
Forbes, B.E.5
Ward, C.W.6
Wallace, J.C.7
-
16
-
-
0027960567
-
Cross-linking of a B25 azidophenylalanine insulin derivative to the carboxyl-terminal region of the α-subunit of the insulin receptor: Identification of a new insulin-binding domain in the insulin receptor
-
Kurose, T., Pashmforoush, M., Yoshimasa, Y., Carroll, R., Schwartz, G. P., Burke, G. T., Katsoyannis, P. G. and Steiner, D. F. (1994) Cross-linking of a B25 azidophenylalanine insulin derivative to the carboxyl-terminal region of the α-subunit of the insulin receptor: identification of a new insulin-binding domain in the insulin receptor. J. Biol. Chem. 269, 29190-29197
-
(1994)
J. Biol. Chem
, vol.269
, pp. 29190-29197
-
-
Kurose, T.1
Pashmforoush, M.2
Yoshimasa, Y.3
Carroll, R.4
Schwartz, G.P.5
Burke, G.T.6
Katsoyannis, P.G.7
Steiner, D.F.8
-
17
-
-
19944363834
-
-
Wan, Z., Xu, B., Huang, K., Chu, Y. C., Li, B., Nakagawa, S. H., Qu, Y., Hu, S. Q., Katsoyannis, P. G. and Weiss, M. A. (2004) Enhancing the activity of insulin at the receptor interface: crystal structure and photo-cross-linking of A8 analogues. Biochemistry 43, 16119-16133
-
Wan, Z., Xu, B., Huang, K., Chu, Y. C., Li, B., Nakagawa, S. H., Qu, Y., Hu, S. Q., Katsoyannis, P. G. and Weiss, M. A. (2004) Enhancing the activity of insulin at the receptor interface: crystal structure and photo-cross-linking of A8 analogues. Biochemistry 43, 16119-16133
-
-
-
-
18
-
-
3142579218
-
Diabetes-associated mutations in insulin: Consecutive residues in the B chain contact distinct domains of the insulin receptor
-
Xu, B., Hu, S. Q., Chu, Y. C., Huang, K., Nakagawa, S. H., Whittaker, J., Katsoyannis, P. G. and Weiss, M. A. (2004) Diabetes-associated mutations in insulin: consecutive residues in the B chain contact distinct domains of the insulin receptor. Biochemistry 43, 8356-8372
-
(2004)
Biochemistry
, vol.43
, pp. 8356-8372
-
-
Xu, B.1
Hu, S.Q.2
Chu, Y.C.3
Huang, K.4
Nakagawa, S.H.5
Whittaker, J.6
Katsoyannis, P.G.7
Weiss, M.A.8
-
19
-
-
3342960841
-
How insulin binds: The B-chain α-helix contacts the L1 β-helix of the insulin receptor
-
Huang, K., Xu, B., Hu, S. Q., Chu, Y. C., Hua, Q. X., Qu, Y., Li, B., Wang, S., Wang, R. Y., Nakagawa, S. H. et al. (2004) How insulin binds: the B-chain α-helix contacts the L1 β-helix of the insulin receptor. J. Mol. Biol. 341, 529-550
-
(2004)
J. Mol. Biol
, vol.341
, pp. 529-550
-
-
Huang, K.1
Xu, B.2
Hu, S.Q.3
Chu, Y.C.4
Hua, Q.X.5
Qu, Y.6
Li, B.7
Wang, S.8
Wang, R.Y.9
Nakagawa, S.H.10
-
20
-
-
0028235085
-
Negative cooperativity in the insulin-like growth factor-I receptor and a chimaeric IGF-I/insulin receptor
-
Christoffersen, C. T., Bornfeldt, K. E., Rotella, C. M., Gonzales, N., Vissing, H., Shymko, R. M., ten Hoeve, J., Groffen, J., Heisterkamp, N. and De Meyts, P. (1994) Negative cooperativity in the insulin-like growth factor-I receptor and a chimaeric IGF-I/insulin receptor. Endocrinology 135, 472-475
-
(1994)
Endocrinology
, vol.135
, pp. 472-475
-
-
Christoffersen, C.T.1
Bornfeldt, K.E.2
Rotella, C.M.3
Gonzales, N.4
Vissing, H.5
Shymko, R.M.6
ten Hoeve, J.7
Groffen, J.8
Heisterkamp, N.9
De Meyts, P.10
-
21
-
-
33751029596
-
Production and characterisation of monoclonal antibodies against insulin-like growth factor type 1 receptor (IGF-1R)
-
Keyhanfar, M., Forbes, B. E., Cosgrove, L. J., Wallace, J. C. and Booker, G. W. (2006) Production and characterisation of monoclonal antibodies against insulin-like growth factor type 1 receptor (IGF-1R). Hybridoma 25, 230-237
-
(2006)
Hybridoma
, vol.25
, pp. 230-237
-
-
Keyhanfar, M.1
Forbes, B.E.2
Cosgrove, L.J.3
Wallace, J.C.4
Booker, G.W.5
-
22
-
-
0027366338
-
Simian virus 40 large tumor antigen is unable to transform mouse embryonic fibroblasts lacking type 1 insulin-like growth factor receptor
-
Sell, C., Rubini, M., Rubin, R., Liu, J. P., Efstratiadis, A. and Baserga, R. (1993) Simian virus 40 large tumor antigen is unable to transform mouse embryonic fibroblasts lacking type 1 insulin-like growth factor receptor. Proc. Natl. Acad. Sci. U.S.A. 90, 11217-11221
-
(1993)
Proc. Natl. Acad. Sci. U.S.A
, vol.90
, pp. 11217-11221
-
-
Sell, C.1
Rubini, M.2
Rubin, R.3
Liu, J.P.4
Efstratiadis, A.5
Baserga, R.6
-
23
-
-
0026038883
-
Insulin and insulin-like growth factor-1 binding specificity is determined by distinct regions of their cognate receptors
-
Schumacher, R., Mosthaf, L., Schlessinger, J., Brandenburg, D. and Ullrich, A. (1991) Insulin and insulin-like growth factor-1 binding specificity is determined by distinct regions of their cognate receptors. J. Biol. Chem. 266, 19288-19295
-
(1991)
J. Biol. Chem
, vol.266
, pp. 19288-19295
-
-
Schumacher, R.1
Mosthaf, L.2
Schlessinger, J.3
Brandenburg, D.4
Ullrich, A.5
-
24
-
-
0027471973
-
Signaling-competent receptor chimaeras allow mapping of major insulin receptor binding domain determinants
-
Schumacher, R., Soos, M. A., Schlessinger, J., Brandenburg, D., Siddle, K. and Ullrich, A. (1993) Signaling-competent receptor chimaeras allow mapping of major insulin receptor binding domain determinants. J. Biol. Chem. 268, 1087-1094
-
(1993)
J. Biol. Chem
, vol.268
, pp. 1087-1094
-
-
Schumacher, R.1
Soos, M.A.2
Schlessinger, J.3
Brandenburg, D.4
Siddle, K.5
Ullrich, A.6
-
25
-
-
0025502197
-
Detection of antigen-antibody interactions by surface plasmon resonance: Application to epitope mapping
-
Fagerstam, L. G., Frostell, A., Karlsson, R., Kullman, M., Larsson, A., Malmqvist, M. and Butt, H. (1990) Detection of antigen-antibody interactions by surface plasmon resonance: application to epitope mapping. J. Mol. Recognit. 3, 208-214
-
(1990)
J. Mol. Recognit
, vol.3
, pp. 208-214
-
-
Fagerstam, L.G.1
Frostell, A.2
Karlsson, R.3
Kullman, M.4
Larsson, A.5
Malmqvist, M.6
Butt, H.7
-
26
-
-
0036186637
-
Characteristics of binding of insulin-like growth factor (IGF)-I and IGF-II analogues to the type 1 IGF receptor determined by BIAcore analysis
-
Forbes, B. E., Hartfield, P. J., McNeil, K. A., Surinya, K. H., Milner, S. J., Cosgrove, L. J. and Wallace, J. C. (2002) Characteristics of binding of insulin-like growth factor (IGF)-I and IGF-II analogues to the type 1 IGF receptor determined by BIAcore analysis. Eur. J. Biochem. 269, 961-968
-
(2002)
Eur. J. Biochem
, vol.269
, pp. 961-968
-
-
Forbes, B.E.1
Hartfield, P.J.2
McNeil, K.A.3
Surinya, K.H.4
Milner, S.J.5
Cosgrove, L.J.6
Wallace, J.C.7
-
27
-
-
0026632363
-
A panel of monoclonal antibodies for the type I insulin-like growth factor receptor. Epitope mapping, effects on ligand binding, and biological activity
-
Soos, M. A., Field, C. E., Lammers, R., Ullrich, A., Zhang, B., Roth, R. A., Andersen, A. S., Kjeldsen, T. and Siddle, K. (1992) A panel of monoclonal antibodies for the type I insulin-like growth factor receptor. Epitope mapping, effects on ligand binding, and biological activity. J. Biol. Chem. 267, 12955-12963
-
(1992)
J. Biol. Chem
, vol.267
, pp. 12955-12963
-
-
Soos, M.A.1
Field, C.E.2
Lammers, R.3
Ullrich, A.4
Zhang, B.5
Roth, R.A.6
Andersen, A.S.7
Kjeldsen, T.8
Siddle, K.9
-
28
-
-
0022194320
-
Human IgG1 and its Fc fragment bind with different affinities to the Fc receptors on the humah U937, HL-60 and ML-1 cell lines
-
Raychaudhuri, G., McCool, D. and Painter, R. H. (1985) Human IgG1 and its Fc fragment bind with different affinities to the Fc receptors on the humah U937, HL-60 and ML-1 cell lines. Mol. Immunol. 22, 1009-1019
-
(1985)
Mol. Immunol
, vol.22
, pp. 1009-1019
-
-
Raychaudhuri, G.1
McCool, D.2
Painter, R.H.3
-
30
-
-
0030756092
-
Identification of common ligand binding determinants of the insulin and insulin-like growth factor 1 receptors: Insights into mechanisms of ligand binding
-
Mynarcik, D. C., Williams, P. F., Schaffer, L., Yu, G. Q. and Whittaker, J. (1997) Identification of common ligand binding determinants of the insulin and insulin-like growth factor 1 receptors: insights into mechanisms of ligand binding. J. Biol. Chem. 272, 18650-18655
-
(1997)
J. Biol. Chem
, vol.272
, pp. 18650-18655
-
-
Mynarcik, D.C.1
Williams, P.F.2
Schaffer, L.3
Yu, G.Q.4
Whittaker, J.5
-
31
-
-
0027499070
-
The use of ATP bioluminescence as a measure of cell proliferation and cytotoxicity
-
Crouch, S. P., Kozlowski, R., Slater, K. J. and Fletcher, J. (1993) The use of ATP bioluminescence as a measure of cell proliferation and cytotoxicity. J. Immunol. Methods 160, 81-88
-
(1993)
J. Immunol. Methods
, vol.160
, pp. 81-88
-
-
Crouch, S.P.1
Kozlowski, R.2
Slater, K.J.3
Fletcher, J.4
-
32
-
-
30944440065
-
Differential activation of insulin receptor isoforms by insulin-like growth factors is determined by the C-domain
-
Denley, A., Brierley, G. V., Carroll, J. M., Lindenberg, A., Booker, G. W., Cosgrove, L. J., Wallace, J. C., Forbes, B. E. and Roberts, Jr, C. T. (2006) Differential activation of insulin receptor isoforms by insulin-like growth factors is determined by the C-domain. Endocrinology 147, 1029-1036
-
(2006)
Endocrinology
, vol.147
, pp. 1029-1036
-
-
Denley, A.1
Brierley, G.V.2
Carroll, J.M.3
Lindenberg, A.4
Booker, G.W.5
Cosgrove, L.J.6
Wallace, J.C.7
Forbes, B.E.8
Roberts Jr, C.T.9
-
33
-
-
0038380346
-
Neutralizing anti-insulin-like growth factor receptor 1 antibodies inhibit receptor function and induce receptor degradation in tumor cells
-
Hailey, J., Maxwell, E., Koukouras, K., Bishop, W. R., Pachter, J. A. and Wang, Y. (2002) Neutralizing anti-insulin-like growth factor receptor 1 antibodies inhibit receptor function and induce receptor degradation in tumor cells. Mol. Cancer Ther. 1, 1349-1353
-
(2002)
Mol. Cancer Ther
, vol.1
, pp. 1349-1353
-
-
Hailey, J.1
Maxwell, E.2
Koukouras, K.3
Bishop, W.R.4
Pachter, J.A.5
Wang, Y.6
-
34
-
-
0029060529
-
Insulin and epidermal growth factor receptors contain the cysteine repeat motif found in the tumor necrosis factor receptor
-
Ward, C. W., Hoyne, P. A. and Flegg, R. H. (1995) Insulin and epidermal growth factor receptors contain the cysteine repeat motif found in the tumor necrosis factor receptor Proteins 22, 141-153
-
(1995)
Proteins
, vol.22
, pp. 141-153
-
-
Ward, C.W.1
Hoyne, P.A.2
Flegg, R.H.3
-
35
-
-
0036420965
-
Molecular recognition in antibody-antigen complexes
-
Sundberg, E. J. and Mariuzza, R. A. (2002) Molecular recognition in antibody-antigen complexes. Adv. Protein Chem. 61, 119-160
-
(2002)
Adv. Protein Chem
, vol.61
, pp. 119-160
-
-
Sundberg, E.J.1
Mariuzza, R.A.2
-
36
-
-
0028342955
-
Positively charged side chains in the insulin-like growth factor-1 C- and D-regions determine receptor binding specificity
-
Zhang, W., Gustafson, T. A., Rutter, W. J. and Johnson, J. D. (1994) Positively charged side chains in the insulin-like growth factor-1 C- and D-regions determine receptor binding specificity. J. Biol. Chem. 269, 10609-10613
-
(1994)
J. Biol. Chem
, vol.269
, pp. 10609-10613
-
-
Zhang, W.1
Gustafson, T.A.2
Rutter, W.J.3
Johnson, J.D.4
-
37
-
-
0032544407
-
The insulin-like growth factor (IGF) binding protein 1 binding epitope on IGF-I probed by heteronuclear NMR spectroscopy and mutational analysis
-
Jansson, M., Andersson, G., Uhlen, M., Nilsson, B. and Kordel, J. (1998) The insulin-like growth factor (IGF) binding protein 1 binding epitope on IGF-I probed by heteronuclear NMR spectroscopy and mutational analysis. J. Biol. Chem. 273, 24701-24707
-
(1998)
J. Biol. Chem
, vol.273
, pp. 24701-24707
-
-
Jansson, M.1
Andersson, G.2
Uhlen, M.3
Nilsson, B.4
Kordel, J.5
-
38
-
-
0025113224
-
The roles of tyroslnes 24, 31, and 60 in the high affinity binding of insulin-like growth factor-I to the type 1 insulin-like growth factor receptor
-
Bayne, M. L., Applebaum, J., Chicchi, G. G., Miller, R. E. and Cascieri, M. A. (1990) The roles of tyroslnes 24, 31, and 60 in the high affinity binding of insulin-like growth factor-I to the type 1 insulin-like growth factor receptor. J. Biol. Chem. 265, 15648-15652
-
(1990)
J. Biol. Chem
, vol.265
, pp. 15648-15652
-
-
Bayne, M.L.1
Applebaum, J.2
Chicchi, G.G.3
Miller, R.E.4
Cascieri, M.A.5
-
39
-
-
33745929892
-
Model for the complex between the insulin-like growth factor I and its receptor: Towards designing antagonists for the IGF-1 receptor
-
Epa, V. C. and Ward, C. W. (2006) Model for the complex between the insulin-like growth factor I and its receptor: towards designing antagonists for the IGF-1 receptor. Protein Eng. Des. Sel. 19, 377-384
-
(2006)
Protein Eng. Des. Sel
, vol.19
, pp. 377-384
-
-
Epa, V.C.1
Ward, C.W.2
-
40
-
-
9144256621
-
Simultaneous blockade of both the epidermal growth factor receptor and the insulin-like growth factor receptor signaling pathways in cancer cells with a fully human recombinant bispecific antibody
-
Lu, D., Zhang, H., Ludwig, D., Persaud, A., Jimenez, X., Burtrum, D., Balderes, P., Liu, M., Bohlen, P., Witte, L. and Zhu, Z. (2004) Simultaneous blockade of both the epidermal growth factor receptor and the insulin-like growth factor receptor signaling pathways in cancer cells with a fully human recombinant bispecific antibody. J. Biol. Chem. 279, 2856-2865
-
(2004)
J. Biol. Chem
, vol.279
, pp. 2856-2865
-
-
Lu, D.1
Zhang, H.2
Ludwig, D.3
Persaud, A.4
Jimenez, X.5
Burtrum, D.6
Balderes, P.7
Liu, M.8
Bohlen, P.9
Witte, L.10
Zhu, Z.11
-
41
-
-
21244441508
-
A fully human recombinant IgG-like bispecific antibody to both the epidermal growth factor receptor and the insulin-like growth factor receptor for enhanced antitumor activity
-
Lu, D., Zhang, H., Koo, H., Tonra, J., Balderes, P., Prewett, M., Corcoran, E., Mangalampalli, V., Bassi, R., Anselma, D. et al. (2005) A fully human recombinant IgG-like bispecific antibody to both the epidermal growth factor receptor and the insulin-like growth factor receptor for enhanced antitumor activity. J. Biol. Chem. 280, 19665-19672
-
(2005)
J. Biol. Chem
, vol.280
, pp. 19665-19672
-
-
Lu, D.1
Zhang, H.2
Koo, H.3
Tonra, J.4
Balderes, P.5
Prewett, M.6
Corcoran, E.7
Mangalampalli, V.8
Bassi, R.9
Anselma, D.10
-
42
-
-
0042515293
-
An anti-insulin-like growth factor I receptor antibody that is a potent inhibitor of cancer cell proliferation
-
Maloney, E. K., McLaughlin, J. L., Dagdigian, N. E., Garrett, L. M., Connors, K. M., Zhou, X. M., Blattler, W. A., Chittenden, T. and Singh, R. (2003) An anti-insulin-like growth factor I receptor antibody that is a potent inhibitor of cancer cell proliferation. Cancer Res. 63, 5073-5083
-
(2003)
Cancer Res
, vol.63
, pp. 5073-5083
-
-
Maloney, E.K.1
McLaughlin, J.L.2
Dagdigian, N.E.3
Garrett, L.M.4
Connors, K.M.5
Zhou, X.M.6
Blattler, W.A.7
Chittenden, T.8
Singh, R.9
-
43
-
-
0037308651
-
A chimaeric humanized single-chain antibody against the type I insulin-like growth factor (IGF) receptor renders breast cancer cells refractory to the mitogenic effects of IGF-I
-
Sachdev, D., Li, S. L., Hartell, J. S., Fujita-Yamaguchi, Y., Miller, J. S. and Yee, D. (2003) A chimaeric humanized single-chain antibody against the type I insulin-like growth factor (IGF) receptor renders breast cancer cells refractory to the mitogenic effects of IGF-I. Cancer Res. 63, 627-635
-
(2003)
Cancer Res
, vol.63
, pp. 627-635
-
-
Sachdev, D.1
Li, S.L.2
Hartell, J.S.3
Fujita-Yamaguchi, Y.4
Miller, J.S.5
Yee, D.6
-
44
-
-
10344247119
-
A recombinant humanized anti-insulin-like growth factor receptor type I antibody (h7C10) enhances the antitumor activity of vinorelbine and anti-epidermal growth factor receptor therapy against human cancer xenografts
-
Goetsch, L., Gonzalez, A., Leger, O., Beck, A., Pauwels, P. J., Haeuw, J. F. and Corvaia, N. (2005) A recombinant humanized anti-insulin-like growth factor receptor type I antibody (h7C10) enhances the antitumor activity of vinorelbine and anti-epidermal growth factor receptor therapy against human cancer xenografts. Int. J. Cancer. 113, 316-328
-
(2005)
Int. J. Cancer
, vol.113
, pp. 316-328
-
-
Goetsch, L.1
Gonzalez, A.2
Leger, O.3
Beck, A.4
Pauwels, P.J.5
Haeuw, J.F.6
Corvaia, N.7
-
45
-
-
4444221565
-
UCSF Chimera - a visualization system for exploratory research and analysis
-
Pettersen, E. F., Goddard, T. D., Huang, C. C., Couch, G. S., Greenblatt, D. M., Meng, E. C. and Ferrin, T. E. (2004) UCSF Chimera - a visualization system for exploratory research and analysis. J. Comput. Chem. 25, 1605-1612
-
(2004)
J. Comput. Chem
, vol.25
, pp. 1605-1612
-
-
Pettersen, E.F.1
Goddard, T.D.2
Huang, C.C.3
Couch, G.S.4
Greenblatt, D.M.5
Meng, E.C.6
Ferrin, T.E.7
|