Prediction methods for nicotine clearance using cotinine and 3-hydroxy-cotinine spot saliva samples II. Model application

Journal of Pharmacokinetics and Pharmacodynamics

Volumn 34, Issue 1, 2007, Pages 23-34

  Levi, Micha ^a,b   Dempsey, Delia A ^a,b   Benowitz, Neal L ^a,b   Sheiner, Lewis B ^a,b  

^a UNIVERSITY OF CALIFORNIA   (United States)

^b SAN FRANCISCO GENERAL HOSPITAL   (United States)

Author keywords

Cotinine; Metabolism; Modeling; Nicotine; NONMEM; Pharmacokinetics; Population

Indexed keywords

3' HYDROXYCOTININE; CYTOCHROME P450 2A6; NICOTINE;

ACCURACY; ANALYTICAL ERROR; ARTICLE; BAYES THEOREM; CONCENTRATION (PARAMETERS); ENZYME ACTIVITY; INTERMETHOD COMPARISON; METABOLISM; POPULATION MODEL; PREDICTION; PRIORITY JOURNAL; SMOKING;

ARYL HYDROCARBON HYDROXYLASES; BAYES THEOREM; BIOTRANSFORMATION; COMPUTER SIMULATION; COTININE; HUMANS; LIVER; METABOLIC CLEARANCE RATE; MIXED FUNCTION OXYGENASES; MODELS, BIOLOGICAL; MODELS, STATISTICAL; NICOTINE; NICOTINIC AGONISTS; PREDICTIVE VALUE OF TESTS; REPRODUCIBILITY OF RESULTS; SALIVA; SMOKING;

EID: 33846328375     PISSN: 1567567X     EISSN: None     Source Type: Journal    
DOI: 10.1007/s10928-006-9026-0     Document Type: Article

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