Effects of highly active antiretroviral therapy (HAART) on psychomotor performance in children with HIV disease

Journal of Neurology

Volumn 253, Issue 12, 2006, Pages 1615-1624

  Koekkoek, Sanneke ^a,d   Eggermont, Laura ^a,d   De Sonneville, Leo ^b   Jupimai, Thidakat ^c   Wicharuk, Saijai ^c   Apateerapong, Wichitea ^c   Chuenyam, Theshinee ^c   Lange, Joep ^c,d,e   Wit, Ferdinand ^d   Pancharoen, Chitsanu ^f   Phanuphak, Praphan ^c,f   Ananworanich, Jintanat ^c  

^a VU UNIVERSITY AMSTERDAM   (Netherlands)

^b LEIDEN UNIVERSITY   (Netherlands)

^c THAI RED CROSS AIDS RESEARCH CENTRE   (Thailand)

^d International Antiviral Therapy Evaluation Center   (Netherlands)

^e UNIVERSITY OF AMSTERDAM   (Netherlands)

^f CHULALONGKORN UNIVERSITY   (Thailand)

Author keywords

ANT; Children; HAART; HIV; Neuropsychological function; Psychomotor function

Indexed keywords

ANTIRETROVIRUS AGENT; CD4 ANTIGEN; EFAVIRENZ; LAMIVUDINE; LAMIVUDINE PLUS NEVIRAPINE PLUS STAVUDINE; LAMIVUDINE PLUS NEVIRAPINE PLUS ZIDOVUDINE; LAMIVUDINE PLUS ZIDOVUDINE; STAVUDINE;

ARTICLE; CHILD; CLINICAL ARTICLE; CONTROLLED STUDY; DRUG EFFECT; DRUG ERUPTION; DRUG WITHDRAWAL; FEMALE; HIGHLY ACTIVE ANTIRETROVIRAL THERAPY; HUMAN; HUMAN IMMUNODEFICIENCY VIRUS INFECTED PATIENT; HUMAN IMMUNODEFICIENCY VIRUS INFECTION; LONGITUDINAL STUDY; MALE; PRIORITY JOURNAL; PSYCHOMOTOR PERFORMANCE; TASK PERFORMANCE; THAILAND;

ANALYSIS OF VARIANCE; ANTI-HIV AGENTS; ANTIRETROVIRAL THERAPY, HIGHLY ACTIVE; CHI-SQUARE DISTRIBUTION; CHILD; CHILD, PRESCHOOL; FEMALE; HIV INFECTIONS; HUMANS; LONGITUDINAL STUDIES; MALE; PILOT PROJECTS; PSYCHOMOTOR PERFORMANCE; REACTION TIME; REGRESSION ANALYSIS; TIME FACTORS;

EID: 33846296225     PISSN: 03405354     EISSN: 14321459     Source Type: Journal    
DOI: 10.1007/s00415-006-0277-x     Document Type: Article

References (47)

1. Arendt G, Giesen HJV, Hefter H, Theisen A (2001) Therapeutic effects of nucleoside analogues on psychomotor slowing in HIV infection. AIDS 15:493-500
2. Bisiacchi PS, Suppiej A, Laverda A (2000) Neuropsychological evaluation of neurologically asymptomatic HIV-infected children. Brain Cogn 43:49-52
3. Blanchette N, Smith ML, King S, Fernandes-Penney A, Read S (2002) Cognitive development in school-age children with vertically transmitted HIV infection. Dev Neuropsychol 21:223-241
4. Brouwers P, Moss H, Wolters P, Eddy J, Balis F, Poplack DG, Pizzo PA (1990) Effect of Continuous-Infusion Zidovudine Therapy on Neuropsychological Functioning in Children with Symptomatic Human-Immunodeficiency-Virus Infection. J Pediatr 117:980-985
5. Buizer AI, de Sonneville LMJ, van den Heuvel - Eibrink MM, Veerman AJ (In press) Chemotherapy intensity as a risk factor for attention and information processing deficits in survivors of childhood acute lymphoblastic leukaemia. Pediatric Blood Cancer
6. Buizer AI, de Sonneville LMJ, van den Heuvel - Eibrink MM, Veerman AJ (In press) Visuomotor control in survivors of childhood acute lymphoblastic leukemia treated with chemotherapy only. J Int Neuropsychol Soc
7. Butler KM, Husson RN, Balis FM, Brouwers P, Eddy J, Elamin D, Gress J, Hawkins M, Jarosinski P, Moss H, Poplack D, Santacroce S, Venzon D, Wiener L, Wolters P, Pizzo PA (1991) Dideoxyinosine in Children with Symptomatic Human-Immunodeficiency-Virus Infection. N Engl J Med 324:137-144
8. Chase C, Ware J, Hittelman J, Blasini I, Smith R, Llorente A, Anisfeld E, Diaz C, Fowler MG, Moye J, Kaligh LI (2000) Early cognitive and motor development among infants born to women infected with human immunodeficiency virus. Pediatrics:106
9. Cohen J (1988) Statistical power analysis for the behavioral sciences. Lawrence Earlbaum Associates, Hillsdale NJ
10. Cohen RA, Boland R, Paul R, Tashima KT, Schoenbaum EE, Celentano DD, Schuman P, Smith DK, Carpenter CCJ (2001) Neurocognitive performance enhanced by highly active antiretroviral therapy in HIV-infected women. AIDS 15:341-345
11. de Sonneville LMJ (1999) Amsterdam neuropsychological tasks:a computer-aided assessment program. In:den Brinker BPLM, Beek PJ, Brand AN, Maarse SJ, Mulder LJM (eds) Cognitive ergonomics, clinical assessment and computer-assisted learning: Computers in psychology. Swets, Lisse, pp 187-203
12. de Sonneville LMJ (2003) Amsterdam Neuropsychological Tasks, manual: database and appendix. Sonar, Amstelveen The Netherlands
13. de Sonneville LMJ (2005) Amsterdamse Neuropsychologische Taken:Wetenschappelijke en klinische toepassingen [Amsterdam Neuropsychological Tasks:Scientific and clinical applications]. Tijdschrift voor Neuropsychologie 0:27-39
14. Decarli C, Fugate L, Falloon J, Eddy J, Katz DA, Friedland RP, Rapoport SI, Brouwers P, Pizzo PA (1991) Brain Growth and Cognitive Improvement in Children with Human Immunodeficiency Virus-Induced Encephalopathy After 6 Months of Continuous Infusion Zidovudine Therapy. J Acquir Immune Defic Syndr Hum Retrovirol 4:585-592
15. Epstein LG, Sharer LR, Oleske JM, Connor EM, Goudsmit J, Bagdon L, Robertguroff M, Koenigsberger MR (1986) Neurologic Manifestations of Human Immunodeficiency Virus-Infection in Children. Pediatrics 78:678-687
16. Ferrando S, van Gorp W, McElhiney M, Goggin K, Sewell M, Rabkin J (1998) Highly active antiretroviral treatment in HIV infection: benefits for neuropsychological function. AIDS 12:F65-F70
17. Fundaro C, Miccinesi N, Baldieri NF, Genovese O, Rendeli C, Segni G (1998) Cognitive impairment in school-age children with asymptomatic HIV infection. AIDS Patient Care STDS 12:135-140
18. Havens J, Whitaker A, Feldman J, Alvarado L, Ehrhardt A (1993) A controlled study of cognitive and language function in school-aged HIV-infected children. Ann N Y Acad Sci 696:249-251
19. Huijbregts S, de Sonneville L, van Spronsen F, Berends I, Licht R, Verkerk P, Sergeant J (2003) Executive motor control under lower and higher controlled processing demands in early and continuously treated phenylketonuria. Neuropsychology 17:369-379
20. Husson RN, Mueller BU, Farley M, Woods L, Kovacs A, Goldsmith JC, Ono J, Lewis LL, Balis FM, Brouwers P, Avramis VI, Church JA, Butler KM, Rasheed S, Jarosinski P, Venzon D, Pizzo PA (1994) Zidovudine and Didanosine Combination Therapy in Children with Human-Immunodeficiency-Virus Infection. Pediatrics 93:316-322
21. Jeremy RJ, Kim S, Nozyce M, Nachman S, Mcintosh K, Pelton SI, Yogev R, Wiznia A, Johnson GM, Krogstad P, Stanley K (2005) Neuropsychological functioning and viral load in stable antiretroviral therapy-experienced HIV-infected children. Pediatrics 115:380-387
22. Kalff AC, de Sonneville LMJ, Hurks PPM, Hendriksen JGM, Kroes M, Feron FJM, Steyaert J, van Zeben TMCB, Vles JSH, Jolles J (2003) Low- and high-level controlled processing in executive motor control tasks in 5-6-year-old children at risk of ADHD. J Child Psychol Psychiatry 44:1049-1057
23. Knight WG, Mellins CA, Levenson RL, Arpadi SM, Kairam R (2000) Brief report: Effects of pediatric HIV infection on mental and psychomotor development. J Pediatr Psychol 25:583-587
24. Letendre SL, McCutchan JA, Childers ME, Woods SP, Lazzaretto D, Heaton RK, Grant I, Ellis RJ (2004) Enhancing antiretroviral therapy for human immunodeficiency virus cognitive disorders. Ann Neurol 56:416-423
25. Levenson RL, Mellins CA, Zawadzki R, Kairam R, Stein Z (1992) Cognitive Assessment of Human-Immunodeficiency-Virus Exposed Children. Am J Dis Child 146:1479-1483
26. Llorente A, Brouwers P, Charurat M, Magder L, Malee K, Mellins C, Ware J, Hittleman J, Mofenson L, Velez-Borras J, Adeniyi-Jones S (2003) Early neurodevelopmental markers predictive of mortality in infants infected with HIV-1. Dev Med Child Neurol 45:76-84
27. McCoig C, Castrejon MM, Castano E, de Suman O, Baez C, Redondo W, McClernon D, Danebower S, Lanier ER, Richardson C, Keller A, Hetherington S, Saez-Llorens X, Ramilo O (2002) Effect of combination anti retroviral therapy on cerebrospinal fluid HIV RNA, HIV resistance, and clinical manifestations of encephalopathy. J Pediatr 141:36-44
28. McCoig C, Castreujon MM, Saavedre-Lozano J, Castano E, Baez C, Lanier ER, Saez-Llorens X, Ramilo O (2004) Cerebrospinal fluid and plasma concentrations of proinflammatory mediators in human immunodeficiency virus-infected children. Pediatr Infect Dis 23:114-118
29. Mckinney RE, Maha MA, Connor EM, Feinberg J, Scott GB, Wulfsohn M, Mcintosh K, Borkowsky W, Modlin JF, Weintrub P, Odonnell K, Gelber RD, Rogers GK, Lehrman SN, Wilfert CM (1991) A Multicenter Trial of Oral Zidovudine in Children with Advanced Human-Immunodeficiency-Virus Disease. New Engl J Med 324:1018-1025
30. Mueller BU, Nelson RP, Sleasman J, Zuckerman J, Heath-Chiozzi M, Steinberg SM, Balis FM, Brouwers P, Hsu A, Saulis R, Sei S, Wood LV, ZEichner S, Katz TTK, Higham C, Aker D, Edgerly M, Jarosinski P, Serchuck L, Whitcup SM, Pizzuti D, Pizzo PA (1998) A phase I/II study of the protease inhibitor ritonavir in children with human immunodeficiency virus infection. Pediatrics 101:335-343
31. Nozyce M, Hoberman M, Arpadi S, Wiznia A, Lambert G, Dobroszycki J, Chang CJ, Stlouis Y (1994) A 12-Month Study of the Effects of Oral Zidovudine on Neurodevelopmental Functioning in A Cohort of Vertically Hiv-Infected Inner-City Children. AIDS 8:635-639
32. Papola P, Alvarez M, Cohen HJ (1994) Developmental and Service Needs of School-Age-Children with Human-Immunodeficiency-Virus Infection - A Descriptive Study. Pediatrics 94:914-918
33. Pizzo PA, Eddy J, Falloon J, Balis FM, Murphy RF, Moss H, Wolters P, Brouwers P, Jarosinski P, Rubin M, Broder S, Yarchoan R, Brunetti A, Maha M, Nusinofflehrman S, Poplack DG (1988) Effect of Continuous Intravenous-Infusion of Zidovudine (Azt) in Children with Symptomatic Hiv Infection. N Engl J Med 319:889-896
34. Puthanait T, Oberdorfer A, Akarathum N, Kanjanavanit S, Wannarit P, Sirisanthana T, Sirisanthana V (2005). Efficacy of highly active antiretroviral therapy in HIV-infected children participating in Thailand's National Access to Antiretroviral Program. Clin Infect Dis 41:100-107
35. Raskino C, Pearson DA, Baker CJ, Lifschitz MH, O'Donnell K, Mintz M, Nozyce M, Brouwers P, Mckinney RE, Jimenez E, Englund JA (1999) Neurologic, neurocognitive, and brain growth outcomes in human immunodeficiency virus-infected children receiving different nucleoside antiretroviral regimens. Pediatrics 104:e32
36. Reger MA, Martin DJ, Cole SL, Strauss G (2005) The relationship between plasma viral load and neuropsychological functioning in HIV-1 infection. Arch Clin Neuropsychol 20:137-143
37. Sacktor N, Skolasky RL, Tarwater PM, McArthur JC, Selnes OA, Becker J, Cohen B, Visscher B, Miller EN (2003) Response to systemic HIV viral load suppression correlates with psychomotor speed performance. Neurology 61:567-569
38. Sacktor N, Tarwater PM, Skolasky RL, McArthur JC, Selnes OA, Becker J, Cohen B, Miller EN (2001) CSF antiretroviral drug penetrance and the treatment of HIV-associated psychomotor slowing. Neurology 57:542-544
39. Suarez S, Baril L, Stankoff B, Khellaf M, Dubois B, Lubetzki C, Bricaire F, Hauw JJ (2001) Outcome of patients with HIV-1-related cognitive impairment on highly active antiretroviral therapy. AIDS 15:195-200
40. Tamula MAT, Wolters PL, Walsek C, ZEichner S (2003) Cognitive decline with immunologic and virologic stability in four children with human immunodeficiency virus disease. Pediatrics 112:679-684
41. Tardieu M, Mayaux MJ, Seibel N, Funckbrentano I, Straub E, Teglas JP, Blanche S (1995) Cognitive Assessment of School-Age-Children Infected with Maternally Transmitted Human-Immunodeficiency-Virus Type-1. J Pediatr 126:375-379
42. von Giesen HJ, Adams O, Koller H, Arendt G (2005) Cerebrospinal fluid HIV viral load in different phases of HIV-associated brain disease. J Neurol 252:801-807
43. von Giesen HJ, Hefter H, Jablonowski H, Arendt G (2000) HAART is neuroprophylactic in HIV-1 infection. J Acquir Immune Defic Syndr 23:380-385
44. von Giesen HJ, Niehues T, Reumel J, Haslinger BA, Ndagijimana J, Arendt G (2003) Delayed motor learning and psychomotor slowing in HIV-infected children. Neuropediatrics 34:177-181
45. Wachsler-Felder JL, Golden CJ (2002) Neuropsychological consequences of HIV in children - A review of current literature. Clin Psychol Rev 22:441-462
46. Wolters PL, Brouwers P, Civitello L, Moss HA (1997) Receptive and expressive language function of children with symptomatic HIV infection and relationship with disease parameters: A longitudinal 24-month follow-up study. AIDS 11:1135-1144
47. Yilmaz A, Stahle L, Hagberg L, Svennerholm B, Fuchs D, Gisslen M (2004) Cerebrospinal fluid and plasma HIV-1 RNA levels and Lopinavir concentrations following Lopinavir/Ritonavir regimen. Scand J Infect Dis 36:823-828