Differential distribution of transforming growth factor beta and receptors in the hyper or hypoproliferative gastric mucosa of developing and adult rats

Histology and Histopathology

Volumn 22, Issue 1-3, 2007, Pages 147-153

  Alvares, Eliana P ^a,b   Jordao L R ^a   Gama, P ^a  

^a UNIVERSITY OF SÃO PAULO   (Brazil)

^b NONE   (Brazil)

Author keywords

Cell proliferation; Gastric mucosa; Rat; T RI; T RIL; TGF

Indexed keywords

TRANSFORMING GROWTH FACTOR BETA; TRANSFORMING GROWTH FACTOR BETA RECEPTOR; TRANSFORMING GROWTH FACTOR BETA1; TRANSFORMING GROWTH FACTOR BETA3;

ANIMAL CELL; ANIMAL TISSUE; ARTICLE; CELL LABELING; CELL PROLIFERATION; CONTROLLED STUDY; CORRELATION ANALYSIS; DIET RESTRICTION; EPITHELIUM CELL; NONHUMAN; ORGANOGENESIS; PROTEIN EXPRESSION; PROTEIN FUNCTION; PROTEIN LOCALIZATION; RAT; REGULATORY MECHANISM; STOMACH EPITHELIUM; STOMACH GLAND; STOMACH MUCOSA;

ANIMALS; ANIMALS, SUCKLING; CELL PROLIFERATION; FOOD DEPRIVATION; GASTRIC MUCOSA; IMMUNOENZYME TECHNIQUES; PROTEIN ISOFORMS; RATS; RATS, WISTAR; RECEPTORS, TRANSFORMING GROWTH FACTOR BETA; TRANSFORMING GROWTH FACTOR BETA;

RATTUS;

EID: 33846287202     PISSN: 02133911     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (38)

1. Alvares E.P. (1987). Circadian rhythms of mitotic activity in gastric mucosa of feeding and fasting rats. Prog. Clin. Biol. Res. 227, 353-360.
2. Alvares E.P. (1992). The effect of fasting on cell proliferation in the gastric mucosa of the 14-day old suckling rat. Braz. J. Med. Biol. Res. 25, 641-649.
3. Alvares E.P. and Gama P. (1993). Fasting enhances cell proliferation of the gastric epithelium during the suckling period in rats. Braz. J. Med. Biol. Res. 26, 869-873.
4. Barnard J.A. and Coffey R.J. (1994). Transforming growth factor beta. In Gut peptides. Walsh J.H. and Dockray G.J. (eds). Raven Press. New York. pp 615-631.
5. Barnard J.A., Beauchamp R.D., Coffey R.J. and Moses H.L. (1989). Regulation of intestinal epithelial cell growth by transforming growth factor type β. Proc. Natl. Acad. Sci. USA 86, 1578-1582.
6. Basque J.R., Chailler P. and Menard D. (2002). Laminins and transforming growth factor-beta maintain cell polarity and functionality of human gastric glandular epithelium. Am. J. Physiol. 282, C873-C884.
7. Biswas S., Chytil A., Washington K., Romero-Gallo J., Gorska A.E., Wirth P.S., Gautan S., Moses H.L. and Grady W.M. (2004). Transforming growth factor beta receptor type II inactivation promotes the establishment and progression of colon cancer. Cancer Res. 15, 4687-4692.
8. Chang J., Park K., Bang Y.J., Kim W.S., Kim D. and Kim S.J. (1997). Expression of transforming growth factor b type II receptor reduces tumorigenicity in human gastric cancer cells. Cancer Res. 57, 2856-2859.
9. de Andrade Sá E.R., Jordão L.R., Takahashi C.A., Alvares E.P. and Gama P. (2003). Ontogenic expression of TGFβ 1, 2, and 3 and its receptors in the rat gastric mucosa. Dev. Dyn. 227, 450-457.
10. Dünker N., Schmitt K., Schuster N. and Krieglstein K. (2002). The role of transforming growth factor Beta-2, Beta-3 in mediating apoptosis in the murine intestinal mucosa. Gastroenterology 122, 1364-1375.
11. Fujisawa T., Kamimura H., Hosaka M., Torii S., Izumi T., Kuwano H. and Takeuchi T. (2004). Functional localization of proprotein-convertase furin and its substrate TGFβ in EGF receptor-expressing gastric chief cells. Growth Factors 22, 51-59.
12. Gama P. and Alvares E.P. (1996). LHRH and somatostatin effects on the cell proliferation of the gastric epithelium of suckling and weaning rats. Regul. Pept. 63, 73-78.
13. Gama P. and Alvares E.P. (1998). Corticosterone treatment inhibits cell proliferation in the gastric epithelium of suckling rats. J. Gastroenterol. 33, 32-38.
14. Gama P. and Alvares E.P. (2000). Early weaning and prolonged nursing induce changes in cell proliferation in the gastric epithelium of developing rats. J. Nutr. 130, 2594-2598.
15. Gold L.I. (1999). The role for transforming growth factor-β (TGF-β) in human cancer. Crit. Rev. Oncog. 10, 303-360.
16. Hu Z.L., Wen J.F., Xiao D.S., Zhen H. and Fu C.Y. (2005). Effects of transforming growth factor on biological behaviors of gastric carcinoma cells. World. J. Gastroenterol. 11, 84-88.
17. Hunt T.E. (1957). Mitotic activity in the gastric mucosa of the rat after fasting and refeeding. Anat. Rec. 127, 539-550.
18. Kang S.H., Bang Y.J., Jong H.S., Seo J.Y., Kim N.K. and Kim S.J. (1999). Rapid induction of p21WAF1 but delayed down-regulation of Cdc25A in the TGF-β-induced cell cycle arrest of gastric carcinoma cells. Br. J. Cancer 80, 1144-1149.
19. Karam S.M. and Leblond C.P. (1992). Identifying and counting epithelial cell types in the corpus of the mouse stomach. Anat. Rec. 232, 231-246.
20. Kulkarni A.B., Huh C.G., Becker D., Geiser A., Lyght M., Flanders K.C., Roberts A.B., Sporn M.B., Ward J.M. and Karlsson S. (1993). Transforming growth factor beta 1 null mutation in mice causes excessive inflammatory response and early death. Proc. Natl. Acad. Sci. USA 90, 770-774.
21. Letterio J.J., Geiser A.G., Kulkarni A.B., Roche N.S., Sporn M.B. and Roberts A.B. (1994). Maternal rescue of transforming growth factor-β1 null mice. Science 264, 1936-1938.
22. Li Q.L., Ito K., Sakakura C., Fukamachi H., Inoue K., Chi X.Z., Lee K.Y., Nomura S., Lee C.W., Han S.B., Kim H.M., Kim W.J., Yamamoto H., Yamashita N., Yano T., Ikeda T., Itohara S., Inazawa J., Abe T., Hagiwara A., Yamagishi H., Ooe A., Kaneda A., Sugimura T., Ushijima T., Bae S.C. and Ito Y. (2002). Causal relationship between the loss of RUNX3 expression and gastric cancer. Cell 109, 113-124.
23. Li X., Zhang Y.Y., Wang Q. and Fu S.B. (2005). Association between endogenous gene expression and growth regulation induced by TGF-beta1 in human gastric cancer cells. World. J. Gastroenterol. 11, 61-68.
24. Massagué J., Blain S.W. and Lo R.S. (2000). TGFβ signaling in growth control, cancer, and heritable disorders. Cell 103, 295-309.
25. McKaig B.C., Makh S.S., Hawkey C.J., Podolsky D.K. and Mahida Y.R. (1999). Normal human colonic subepithelial myofibroblasts enhance epithelial migration (restitution) via TGF-beta3. Am. J. Physiol. 276, G1087-G1093.
26. Mowat A.Mc.I., Garside P., Fitton L.A., Higley H.R. and Carlino J.A. (1996). Regulatory activity of endogenous and exogenous transforming growth factor β in experimental intestinal immunopathology. Growth Factors 13, 75-85.
27. Naef M., Ishiwata T., Friess H., Büchler M.W., Gold L.I. and Korc M. (1997). Differential localization of transforming growth factor-β isoforms in human gastric mucosa and overexpression in gastric carcinoma. Int. J. Cancer 71, 131-137.
28. Nakajima N. and Kuwayama H. (1993). Effects of transforming growth factor α and β on rabbit gastric epithelial cell proliferation: a preliminary report. J. Clin. Gastroenterol. 17(Suppl. 1), S121-S124.
29. Oliveira C., Seruca R., Seixas M. and Sobrinho-Simões M. (1998). The clinicopathological features of gastric carcinomas with microsatellite instability may be mediated by mutations of different "target genes". A study of the TGFβ RII, IGFII R, and BAX genes. Am. J. Pathol. 153, 1211-1219.
30. Parekh T.V., Gama P., Wen X., Demopoulos R., Mungeeer J.S., Carcangiu M.L., Reiss M. and Gold L.I. (2002). Transforming growth factor β signaling is disabled early in human endometrial carcinogenesis concomitant with loss of growth inhibition Cancer Res. 62, 2778-2790.
31. Park K., Kim S.J., Bang Y.J., Park J.G., Kim N.K., Roberts A.B. and Sporn M.B. (1994). Genetic changes in the transforming growth factor beta (TGF-beta) type II receptor gene in human gastric cancer cells: correlation with sensitivity to growth inhibition by TGF-beta. Proc. Natl. Acad. Sci. USA 91, 8772-8776.
32. Pelton R.W., Saxena B., Jones M., Moses H.L. and Gold L.I. (1991). Immunohistochemical localization of TGFβ1, TGFβ2, and TGFβ3 in the mouse embryo: expression patterns suggest multiple roles during embryonic development. J. Cell Biol. 115, 1091-1105.
33. Penttila I.A., Van Spriel A.B., Zhang M.F., Xian C.J., Steeb C.B., Cummins A.G., Zola H. and Read L.C. (1998). Transforming growth factor-β levels in maternal milk and expression in postnatal rat duodenum and ileum. Pediatric Res. 44, 524-531.
34. Rokutan K., Yamada M., Torigoe J. and Saito T. (1998). Transforming growth factor-β inhibits proliferation and maturation of cultured guinea pig gastric pit cells. Am. J. Physiol. 275, G526-G533.
35. Shull M.M., Ormsby I., Kier A.B., Pawlowski S., Diebold R.J., Yin M., Allen R., Sidman C., Proetzel G., Calvin D., Annunziata N. and Doetschman T. (1992). Targeted disruption of the mouse transforming growth factor-β1 gene results in multifocal inflammatory disease. Nature 359, 693-699.
36. Tanigawa T., Pai R., Arakawa T., Higuchi K. and Tarnawski A.S. (2005). TGF-β signaling pathway: its role in gastrointestinal pathophysiology and modulation of ulcer healing. J. Physiol. Pharmacol. 56, 3-13.
37. Tsutsumi S., Tomisato W., Hoshino T., Tsuchiya T. and Mizushima T. (2002). Transforming growth factor-β1 is responsible for maturation-dependent spontaneous apoptosis of cultured gastric pit cells. Exp. Biol. Med. 227, 402-411.
38. Yamamoto M., Maehara Y., Sakaguchi Y., Kusumoto T., Ichiyoshi Y. and Sugimachi K. (1996). Transforming growth factor-β 1 induces apoptosis in gastric cancer cells through a p53-independent pathway. Cancer 77, 1628-33.