Dopamine D1 and D2 receptors regulate extracellular lactate and glucose concentrations in the nucleus accumbens

Brain Research

Volumn 1133, Issue 1, 2007, Pages 193-199

  Uehara, Takashi ^a   Sumiyoshi, Tomiki ^a   Itoh, Hiroko ^a   Kurachi, Masayoshi ^a  

^a UNIVERSITY OF TOYAMA   (Japan)

Author keywords

Brain energy metabolism; D1,D2 receptor; Glucose; Lactate; Microdialysis; Nucleus accumbens; Schizophrenia

Indexed keywords

2,3,4,5 TETRAHYDRO 7,8 DIHYDROXY 1 PHENYL 1H 3 BENZAZEPINE; 8 CHLORO 2,3,4,5 TETRAHYDRO 3 METHYL 5 PHENYL 1H 3 BENZAZEPIN 7 OL HYDROGEN MALEATE; APOMORPHINE; BROMOCRIPTINE; DOPAMINE 1 RECEPTOR; DOPAMINE 2 RECEPTOR; GLUCOSE; LACTIC ACID; NOMIFENSINE; POTASSIUM ION; QUINELORANE; QUINPIROLE; TETRODOTOXIN; VERATRIDINE;

ADOLESCENT; ANIMAL EXPERIMENT; ARTICLE; BRAIN METABOLISM; DOPAMINERGIC TRANSMISSION; DOSE RESPONSE; ENERGY METABOLISM; GLUCOSE BRAIN LEVEL; MALE; MICRODIALYSIS; NERVE CONDUCTION; NONHUMAN; NUCLEUS ACCUMBENS; PRIORITY JOURNAL; RAT;

ANIMALS; APOMORPHINE; ASTROCYTES; BROMOCRIPTINE; CELL COMMUNICATION; DOPAMINE; DOPAMINE AGONISTS; DOSE-RESPONSE RELATIONSHIP, DRUG; EXTRACELLULAR FLUID; GLUCOSE; LACTIC ACID; MALE; MICRODIALYSIS; NEURONS; NUCLEUS ACCUMBENS; POTASSIUM; RATS; RATS, WISTAR; RECEPTORS, DOPAMINE D1; RECEPTORS, DOPAMINE D2; SODIUM CHANNEL BLOCKERS; UP-REGULATION;

EID: 33846286032     PISSN: 00068993     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.brainres.2006.11.040     Document Type: Article

References (44)

1. Andersen S.L., and Gazzara R.A. The ontogeny of apomorphine-induced alterations of neostriatal dopamine release: effects on spontaneous release. J. Neurochem. 61 (1993) 2247-2255
2. Beck T., Moller H.G., Nowak K., Krieglstein J., and Kuschinsky K. Alterations in regional energy metabolism in rat brain produced by small and by large doses of apomorphine: possible relations to autoreceptors. Eur. J. Pharmacol. 139 (1987) 139-146
3. Blackwood N.J., Howard R.J., Bentall R.P., and Murray R.M. Cognitive neuropsychiatric models of persecutory delusions. Am. J. Psychiatry 158 (2001) 527-539
4. Breier A., Su T.P., Saunders R., Carson R.E., Kolachana B.S., de Bartolomeis A., Weinberger D.R., Weisenfeld N., Malhotra A.K., Eckelman W.C., and Pickar D. Schizophrenia is associated with elevated amphetamine-induced synaptic dopamine concentrations: evidence from a novel positron emission tomography method. Proc. Natl. Acad. Sci. U. S. A. 94 (1997) 2569-2574
5. Cooper J.R., Bloom F.E., and Roth R.H. Dopamine. In: Cooper J.R., Bloom F.E., and Roth R.H. (Eds). The Biochemical Basis of Neuropharmacology (2003), Oxford Univ. Press, Inc., New York 225-270
6. Cremer J.E., Cunningham V.J., and Seville M.P. Relationships between extraction and metabolism of glucose, blood flow, and tissue blood volume in regions of rat brain. J. Cereb. Blood Flow Metab. 3 (1983) 291-302
7. Crow T.J. Positive and negative schizophrenic symptoms and the role of dopamine. Br. J. Psychiatry 137 (1980) 383-386
8. Donzanti B.A., Hite J.F., and Yamamoto B.K. Extracellular glutamate levels increase with age in the lateral striatum: potential involvement of presynaptic D-2 receptors. Synapse 13 (1993) 376-382
9. Ebmeier K.P., Blackwood D.H., Murray C., Souza V., Walker M., Dougall N., Moffoot A.P., O'Carroll R.E., and Goodwin G.M. Single-photon emission computed tomography with 99(mTc-exametazime in unmedicated schizophrenic patients. Biol. Psychiatry 33 (1993) 487-495
10. Engber T.M., Anderson J.J., Boldry R.C., Kuo S., and Chase T.N. N-methyl-d-aspartate receptor blockade differentially modifies regional cerebral metabolic responses to D1 and D2 dopamine agonists in rats with a unilateral 6-hydroxydopamine lesion. Neuroscience 54 (1993) 1051-1061
11. Exposito I., Sanz B., Porras A., and Mora F. Effects of apomorphine and l-methionine sulphoximine on the release of excitatory amino acid neurotransmitters and glutamine in the striatum of the conscious rat. Eur. J. Neurosci. 6 (1994) 287-291
12. Exposito I., Del Arco A., Segovia G., and Mora F. Endogenous dopamine increases extracellular concentrations of glutamate and GABA in striatum of the freely moving rat: involvement of D1 and D2 dopamine receptors. Neurochem. Res. 24 (1999) 849-856
13. Fellows L.K., Boutelle M.G., and Fillenz M. Extracellular brain glucose levels reflect local neuronal activity: a microdialysis study in awake, freely moving rats. J. Neurochem. 59 (1992) 2141-2147
14. Fellows L.K., Boutelle M.G., and Fillenz M. Physiological stimulation increases nonoxidative glucose metabolism in the brain of the freely moving rat. J. Neurochem. 60 (1993) 1258-1263
15. Fox P.T., Raichle M.E., Mintun M.A., and Dence C. Nonoxidative glucose consumption during focal physiologic neural activity. Science 241 (1988) 462-464
16. Korf J., and de Boer J. Lactography as an approach to monitor glucose metabolism on-line in brain and muscle. Int. J. Biochem. 22 (1990) 1371-1378
17. Kuhr W.G., and Korf J. Extracellular lactic acid as an indicator of brain metabolism: continuous on-line measurement in conscious, freely moving rats with intrastriatal dialysis. J. Cereb. Blood Flow Metab. 8 (1988) 130-137
18. Kuhr W.G., van den Berg C.J., and Korf J. In vivo identification and quantitative evaluation of carrier-mediated transport of lactate at the cellular level in the striatum of conscious, freely moving rats. J. Cereb. Blood Flow Metab. 8 (1988) 848-856
19. Laruelle M., Abi-Dargham A., van Dyck C.H., Gil R., D'Souza C.D., Erdos J., McCance E., Rosenblatt W., Fingado C., Zoghbi S.S., Baldwin R.M., Seibyl J.P., Krystal J.H., Charney D.S., and Innis R.B. Single photon emission computerized tomography imaging of amphetamine-induced dopamine release in drug-free schizophrenic subjects. Proc. Natl. Acad. Sci. U. S. A. 93 (1996) 9235-9240
20. Liddle P.F., Friston K.J., Frith C.D., Hirsch S.R., Jones T., and Frackowiak R.S. Patterns of cerebral blood flow in schizophrenia. Br. J. Psychiatry 160 (1992) 179-186
21. McCulloch J., and Harper A.M. Cerebral circulation: effect of stimulation and blockade of dopamine receptors. Am. J. Physiol. 233 (1977) H222-H227
22. Palacios J.M., and Wiederhold K.H. Dopamine D2 receptor agents, but not dopamine D1, modify brain glucose metabolism. Brain Res. 327 (1985) 390-394
23. Paxinos G., and Watson C. The Rat Brain in Stereotaxic Coordinates (1998), Academic Press
24. Pellerin L. Lactate as a pivotal element in neuron-glia metabolic cooperation. Neurochem. Int. 43 (2003) 331-338
25. Pellerin L., and Magistretti P.J. Glutamate uptake into astrocytes stimulates aerobic glycolysis: a mechanism coupling neuronal activity to glucose utilization. Proc. Natl. Acad. Sci. U. S. A. 91 (1994) 10625-10629
26. Pellerin L., Pellegri G., Bittar P.G., Charnay Y., Bouras C., Martin J.L., Stella N., and Magistretti P.J. Evidence supporting the existence of an activity-dependent astrocyte-neuron lactate shuttle. Dev. Neurosci. 20 (1998) 291-299
27. Pfefferbaum A., and Zipursky R.B. Neuroimaging studies of schizophrenia. Schizophr. Res. 4 (1991) 193-208
28. Pizzolato G., Soncrant T.T., and Rapoport S.I. Time-course and regional distribution of the metabolic effects of bromocriptine in the rat brain. Brain Res. 341 (1985) 303-312
29. Porras A., and Mora F. Dopamine-glutamate-GABA interactions and ageing: studies in the striatum of the conscious rat. Eur. J. Neurosci. 7 (1995) 2183-2188
30. Reid M.S., Herrera-Marschitz M., Kehr J., and Ungerstedt U. Striatal dopamine and glutamate release: effects of intranigral injections of substance P. Acta Physiol. Scand. 140 (1990) 527-537
31. Seeman P., Weinshenker D., Quirion R., Srivastava L.K., Bhardwaj S.K., Grandy D.K., Premont R.T., Sotnikova T.D., Boksa P., El-Ghundi M., O'Dowd B.F., George S.R., Perreault M.L., Mannisto P.T., Robinson S., Palmiter R.D., and Tallerico T. Dopamine supersensitivity correlates with D2High states, implying many paths to psychosis. Proc. Natl. Acad. Sci. U. S. A. 102 (2005) 3513-3518
32. Shilliam C.S., and Heidbreder C.A. Gradient of dopamine responsiveness to dopamine receptor agonists in subregions of the rat nucleus accumbens. Eur. J. Pharmacol. 477 (2003) 113-122
33. Sokoloff L. Relation between physiological function and energy metabolism in the central nervous system. J. Neurochem. 29 (1977) 13-26
34. Sokoloff L., Reivich M., Kennedy C., Des Rosiers M.H., Patlak C.S., Pettigrew K.D., Sakurada O., and Shinohara M. The [14C]deoxyglucose method for the measurement of local cerebral glucose utilization: theory, procedure, and normal values in the conscious and anesthetized albino rat. J. Neurochem. 28 (1977) 897-916
35. Sumiyoshi T., Stockmeier C.A., Overholser J.C., Thompson P.A., and Meltzer H.Y. Dopamine D4 receptors and effects of guanine nucleotides on [3H]raclopride binding in postmortem caudate nucleus of subjects with schizophrenia or major depression. Brain Res. 681 (1995) 109-116
36. Sumiyoshi T., Seeman P., Uehara T., Itoh H., Tsunoda M., and Kurachi M. Increased proportion of high-affinity dopamine D2 receptors in rats with excitotoxic damage of the entorhinal cortex, an animal model of schizophrenia. Brain Res. Mol. Brain Res. 140 (2005) 116-119
37. Tsacopoulos M., and Magistretti P.J. Metabolic coupling between glia and neurons. J. Neurosci. 16 (1996) 877-885
38. Uehara T., Kurata K., Sumiyoshi T., and Kurachi M. Immobilization stress-induced increment of lactate metabolism in the basolateral amygdaloid nucleus is attenuated by diazepam in the rat. Eur. J. Pharmacol. 459 (2003) 211-215
39. Uehara T., Sumiyoshi T., Matsuoka T., Tanaka K., Tsunoda M., Itoh H., and Kurachi M. Enhancement of lactate metabolism in the basolateral amygdala by physical and psychological stress: Role of benzodiazepine receptors. Brain Res. 1065 (2005) 86-91
40. Uehara T., Sumiyoshi T., Matsuoka T., Itoh H., and Kurachi M. Role of 5-HT(1A) receptors in the modulation of stress-induced lactate metabolism in the medial prefrontal cortex and basolateral amygdala. Psychopharmacology (Berlin) 186 (2006) 218-225
41. van der Kuil J.H., and Korf J. On-line monitoring of extracellular brain glucose using microdialysis and a NADPH-linked enzymatic assay. J. Neurochem. 57 (1991) 648-654
42. Wise R.A., Mendrek A., and Carlezon Jr. W.A. MK-801 (dizocilpine): synergist and conditioned stimulus in bromocriptine-induced psychomotor sensitization. Synapse 22 (1996) 362-368
43. Yamamoto B.K., and Davy S. Dopaminergic modulation of glutamate release in striatum as measured by microdialysis. J. Neurochem. 58 (1992) 1736-1742
44. Zahm D.S. An integrative neuroanatomical perspective on some subcortical substrates of adaptive responding with emphasis on the nucleus accumbens. Neurosci. Biobehav. Rev. 24 (2000) 85-105