The effects of low dose aluminum on hemorheological and hematological parameters in rats

Archives of Toxicology

Volumn 81, Issue 1, 2007, Pages 11-17

  Turgut, Sebahat ^a   Bor Kucukatay, Melek ^a   Emmungil, Gülten ^a   Atsak, Piray ^a   Turgut, Günfer ^a  

^a PAMUKKALE UNIVERSITY   (Turkey)

Author keywords

Aluminum; Blood viscosity; Erythrocyte aggregation; Hemorheology; Plasma viscosity; Red blood cell deformability

Indexed keywords

ALUMINUM; ALUMINUM SULFATE; SODIUM CHLORIDE;

ANALYZER; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; BLOOD CLOTTING; BLOOD RHEOLOGY; BLOOD SAMPLING; BLOOD VISCOSITY; BODY WEIGHT; CONTROLLED STUDY; ENVIRONMENTAL EXPOSURE; ERYTHROCYTE AGGREGATION; ERYTHROCYTE DEFORMABILITY; ERYTHROCYTE MEMBRANE; HEMATOCRIT; HEMATOLOGICAL PARAMETERS; MALE; MEAN CORPUSCULAR VOLUME; NONHUMAN; PLASMA VISCOSITY; PRIORITY JOURNAL; RAT; SHEAR STRESS; VISCOMETER;

ALUM COMPOUNDS; ANIMALS; BLOOD VISCOSITY; DOSE-RESPONSE RELATIONSHIP, DRUG; ERYTHROCYTE AGGREGATION; ERYTHROCYTE DEFORMABILITY; ERYTHROCYTE INDICES; ERYTHROCYTES; HEMATOCRIT; HEMATOLOGY; HEMOGLOBINOMETRY; HEMORHEOLOGY; INJECTIONS, INTRAPERITONEAL; MALE; RATS; RATS, WISTAR;

ANIMALIA; RATTUS;

EID: 33846267650     PISSN: 03405761     EISSN: None     Source Type: Journal    
DOI: 10.1007/s00204-006-0119-8     Document Type: Article

References (31)

1. Alfrey AC (1985) Gastrointestinal absorption of aluminum. Clin Nephrol 24:84-87
2. Bazzoni GB, Bollini AN, Hernandez GN, Contini Mdel C, Chiarotto MM, Rasia ML (2005) In vivo effect of aluminium upon the physical properties of the erythrocyte membrane. J Inorg Biochem 99:822-827
3. Chien S (1975) Biophysical behavior of red cells in suspensions. In: Surgenor DM (ed) The red blood cell. Academic, New York, pp 1031-1133
4. Domingo JL (1995) Reproductive and developmental toxicity of aluminum. Neurotoxicol Teratol 17:515-521
5. Drüeke TB, Lacour B, Touam M, Jucquel JP, Plachot JJ, Cournot-Witmer G, Galle P (1986a) Effect of aluminum on hematopoiesis. Kidney Int 18:45-48
6. Drüeke TB, Touam M, Lacour B (1986b) Aluminum induced microcytic in experimental chronic renal failure. Nefrologia 6:67-69
7. El-Maraghy SA, Gad MZ, Fahim AT, Hamdy MA (2001) Effect of cadmium and aluminum intake on the antioxidant status and lipid peroxidation in rat tissues. J Biochem Mol Toxicol 15:207-214
8. Farina M, Lara FS, Brandao R, Jacques R, Rocha JBT (2002) Effects of aluminum sulfate on erythropoiesis in rats. Toxicol Lett 132:131-139
9. Farina M, Rotta LN, Soares FA, Jardim F, Jacques R, Souza DO, Rocha JB (2005) Hematological changes in rats chronically exposed to oral aluminum. Toxicology 209:29-37
10. Fulton B, Jeffery EH (1994) Heme oxygenase induction: a possible factor in aluminum-associated anemia. Biol Trace Elem Res 40:9-19
11. Hardeman MR, Dobbe JG, Ince C (2001) The laser-assisted optical rotational cell analyzer (LORCA) as red blood cell aggregometer. Clin Hemorheol Microcirc 25:1-11
12. Hardeman MR, Goedhart PT, Dobbe JGG, Lettinga KP (1994) Laser assisted optical rotational cell analyzer (LORCA): a new instrument for measurement of various structural hemorhelogical parameters. Clin Hemorheol 14:605-618
13. Jain SK, Abreo K, Duett J, Sella M (1995) Lipofusion products lipid peroxides and aluminum accumulation in red blood cells of hemodialyzed patients. Am J Nephrol 15:306-311
14. Kaiser L, Schwartz K, Burnatowska-Hledin MA, Mayor G (1984) Microcytic anemia secondary to intraperitoneal aluminum in normal and uremic rats. Kidney Int 26:269-274
15. Kim MS, Lenore S, Clesceri LS (2001) Aluminum exposure: a study of an effect on cellular growth rate. Sci Total Environ 278:127-135
16. Levesque L, Mizzen CA, McLachlan DR, Fraser PE (2000) Ligand specific effects on aluminium incorporation and toxicity in neurons and astrocytes. Brain Res 877:191-202
17. Mahieu S, del Carmen Contini M, Gonzalez M, Millen N, Elias MM (2000) Aluminum toxicity. Hematological effects. Toxicol Lett 111:235-242
18. Mohandas N, Chasis JA (1993) Red blood cell deformability, membrane material properties and shape: regulation by transmembrane, skeletal and cytosolic proteins and lipids. Semin Hematol 30:171-192
19. Mohandas N, Chasis JA, Shohet SB (1983) The influence of membrane skeleton on red cell deformability, membrane material properties, and shape. Semin Hematol 20:225-242
20. Nayak P (2002) Aluminum: Impacts and disease. Environ Res 89:101-105
21. Osinska E, Kanoniuk D, Kusiak A (2004) Aluminum hemotoxicity mechanisms. Ann Univ Mariae Curie Sklodowska 59:411-416
22. Oteiza PI (1994) A mechanism for the stimulatory effect of aluminum on iron-induced lipid peroxidation. Arch Biochem Biophys 308:374-379
23. Parkinson TS, Ward MK, Kerr DNS (1981) Dialysis encephalopathy, bone disease and anaemia: the aluminum intoxication syndrome during regular haemodialysis. J Clin Pathol 34:1285-1294
24. Schmid-Schönbein H (1988) Fluid dynamics and hemorheology in vivo: The interactions of hemodynamic parameters and hemorheological 'properties' in determining the flow behavior of blood in microvascular networks. In: Lowe GDO (eds) Clinical blood rheology. CRC, Florida pp 129-219
25. Shiga T, Maeda N, Kon K (1990) Erythrocyte rheology. Crit Rev Oncol Hematol 10(1):9-48
26. Stuart J, Nash GB (1990) Red cell deformability and haematological disorders. Blood Rev 4:141-147
27. Suwalsky M, Norris B, Kiss T, Zatta P (2002) Effects of Al(III) speciation on cell membranes and molecular models. Coordin Chem Rev 228:285-295
28. Suwalsky M, Ungerer B, Villena F, Norris B, Cardenas H, Zatta P (1999) Interactions of Al(acac)3 with cell membranes and model phospholipid bilayers. J Inorg Biochem 75:263-268
29. Turgut G, Kaptanoǧlu B, Turgut S, Enli Y, Genç O (2004) Effects of chronic aluminum administration on blood and liver iron-related parameters in mice. Yonsei Med J 45:135-139
30. Vittori D, Nesse A, Perez G, Garbossa G (1999) Morphologic and functional alterations of erythroid cells induced by long-term ingestion of aluminium. J Inorg Biochem 76:113-120
31. Zaman K, Zaman W, Siddique H (1993) Hematological and enzymatic results of aluminum intoxication in rats. Comp Biochem Physiol 105:73-76