Separation of glycyrrhizic acid and liquiritin from Glycyrrhiza uralensis Fisch extract by three-liquid-phase extraction systems

Separation and Purification Technology

Volumn 53, Issue 3, 2007, Pages 216-223

  Shen, Shufeng ^a,b   Chang, Zhidong ^a   Liu, Ji ^a   Sun, Xinghua ^a   Hu, Xin ^a   Liu, Huizhou ^a  

^a INSTITUTE OF PROCESS ENGINEERING   (China)

^b UNIVERSITY OF CHINESE ACADEMY OF SCIENCES   (China)

Author keywords

FTIR; Glycyrrhizia uralensis Fisch; Glycyrrhizic acid; Liquiritin; Separation; Three liquid phase extraction

Indexed keywords

EXTRACTION; FOURIER TRANSFORM INFRARED SPECTROSCOPY; HYDROGEN BONDS; PH EFFECTS; PHASE SEPARATION; PHOSPHATES;

GLYCYRRHIZIA URALENSIS FISCH; GLYCYRRHIZIC ACIDS; LIQUIRITIN; THREE LIQUID PHASE EXTRACTION;

ORGANIC ACIDS;

GLYCYRRHIZA; GLYCYRRHIZA URALENSIS;

EID: 33846260261     PISSN: 13835866     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.seppur.2006.07.003     Document Type: Article

References (23)

1. Hu J.F., and Shen F.J. A survey of the studies on chemical constituents of Glycyrrhiza. Nat. Prod. Res. Dev. 8 (1996) 77-91
2. Rauchensteiner F., Matsumura Y., Yamamoto Y., Yamaji S., and Tani T. Analysis and comparison of Radix Glycyrrhizae (licorice) from Europe and China by capillary-zone electrophoresis (CZE). J. Pharm. Biomed. Anal. 38 (2005) 594-600
3. Zhou Y., Wang M.K., Liao X., Zhu X.M., Peng S.L., and Ding L.S. Rapid identification of compounds in Glycyrrhiza Uralensis by liquid chromatography/Tandem mass spectrometry. Chin. J. Anal. Chem. 32 (2004) 174-178
4. Niu G.G., Xie Y.C., Lou J.F., and Liu H.Z. Isolation and purification of glycyrrhizic acid with solvent extraction. Sep. Purif. Technol. 44 (2005) 189-196
5. Li Q.L., Zhou M.H., and Chen J.N. Application of supercritical fluid extraction in the analysis of Glycyrrhizic acid. J. Instrum. Anal. 17 1 (1998) 37-40
6. Fu D.H., Liu A.L., Deng K.N., Zhou T.J., and Xiao J.D. Study on the adsorption behavior and application of DM-130 resin to purifying glycyrrhizic acid. Nat. Prod. Res. Dev. 14 1 (2001) 60-64
7. Thomas H.B.S., Howaed W.Z., and Alexis D.B. Separation of major components in licorice using high-performance liquid chromatography. J. Chromatogr. 175 (1979) 350-355
8. Jiang Y., Lu H.T., and Chen F. Preparative purification of glycyrrhizin extracted from the root of liquorice using high-speed counter-current chromatography. J. Chromatogr. 1033 1 (2004) 183-186
9. Wang Q.E., Lee F.S.C., and Wang X. Isolation and purification of inflacoumarin A and licochalcone A from licorice by high-speed counter-current chromatography. J. Chromatogr. A 1048 1 (2004) 51-57
10. Yu S.H., Wu S.J., Jin F.X., and Guo Y. Isolation and purification of Glycyrrhizin from Licorice with Resin Column. Food Ferment. Ind. 25 1 (1998) 40-43
11. Feng F.S., Xuan C.S., Chen S.W., Chang Y., and Qiao B.Z. Application of an adsorbent AB-8 in extraction and separation of glycyrrhizic acid. Nat. Prod. Res. Dev. 10 1 (1997) 60-64
12. Liu Q., Yang L., Wu X., and Chen J. Study on purification of glycyrrhizic acid with macroporous adsorption resin. Zhong Yao Cai. 26 5 (2003) 357-359
13. Fu B., Liu J., Li H., Li L., Lee F.S., and Wang X. The application of macroporous resins in the separation of licorice flavonoids and glycyrrhizic acid. J. Chromatogr. A 1089 1/2 (2005) 18-24
14. Wang Q.E., Ma S.M., Fu B.Q., Lee F.S., and Wang X.Y. Development of multi-stage countercurrent extraction technology for the extraction of glycyrrhizic acid (GA) from licorice (Glycyrrhiza uralensis Fisch). Biochem. Eng. J. 21 3 (2004) 285
15. Ma J.G., Xiu Z.L., Zhang D.J., and Jia L.Y. Concentration and separation of glycyrrhizic acid by foam separation. J. Chem. Technol. Biotechnol. 77 (2002) 720-724
16. Tan T.W., Huo Q., and Ling Q. Purification of glycyrrhizin from Glycyrrhiza uralensis Fisch with ethanol/phosphate aqueous two phase system. Biotechnol. Lett. 24 (2002) 1417-1420
17. Mojski M., and Gluch I. Characteristics and applications of three-phase extraction systems. J. Anal. Chem. 51 4 (1996) 329-342
18. Shen S.F., Chang Z.D., Sun X.H., Hu X., and Liu H.Z. Application and recycling of tri-block copolymer in three-phase extraction system. Proceedings of the International Conference of Solvent Extraction (ISEC2005). Beijing (2005) 1360-1365
19. Shen S.F., Chang Z.D., and Liu H.Z. Three-liquid-phase extraction systems for separation of phenol and p-nitrophenol from wastewater. Sep. Purif. Technol. 49 3 (2006) 217-222
20. Shen S.F., Chang Z.D., Sun X.H., and Liu H.Z. Process integration for production of 6-aminopenicillanic acid from penicillin G cultivation broth. Process Biochem. 41 3 (2006) 571-574
21. Cai W.B., Zhu S.L., and Piao X.L. Extraction equilibria of formic and acetic acids from aqueous solution by phosphate-containing extractants. J. Chem. Eng. Data 46 (2001) 1472-1475
22. Jiang J.Z., Li W.H., Gao H.C., and Wu J.G. Extraction of inorganic acids with neutral phosphorus extractants based on a reverse micelle/microemulsion mechanism. J. Colloid Interface Sci. 268 (2003) 208-214
23. Nivaggioli T., Alexandridis P., and Hatton T.A. Fluorescence probe studies of pluronic copolymer solutions as a function of temperature. Langmuir 11 (1995) 730-737