Cross-reactive immune responses in mice after genetic vaccination with cDNA encoding hantavirus nucleocapsid proteins

Vaccine

Volumn 25, Issue 9, 2007, Pages 1690-1699

  Lindkvist, Marie ^a,b   Lahti, Katarina ^a,b   Lilliehöök, Bo ^a   Holmström, Anna ^a   Ahlm, Clas ^b   Bucht, Göran ^a  

^a SWEDISH DEFENCE RESEARCH AGENCY   (Sweden)

^b UMEÅ UNIVERSITY   (Sweden)

Author keywords

Cross reactivity; DNA vaccines; Hantavirus; Immune response

Indexed keywords

AMINO ACID; COMPLEMENTARY DNA; DNA VACCINE; EPITOPE; NUCLEOCAPSID PROTEIN; VIRUS VACCINE;

ANIMAL CELL; ANIMAL EXPERIMENT; ANTIBODY RESPONSE; ANTIBODY TITER; ANTIGEN SPECIFICITY; ARTICLE; B LYMPHOCYTE; COMPUTER PROGRAM; CONTROLLED STUDY; CROSS REACTION; DNA IMMUNIZATION; FEMALE; GENE DELETION; GENE GUN; HANTAVIRUS; IMMUNOGENICITY; MOUSE; NONHUMAN; NUCLEOTIDE SEQUENCE; POLYCLONAL ACTIVATION; PREDICTION; PRIORITY JOURNAL; PROTEIN VARIANT; PUUMALA VIRUS; QUANTITATIVE ANALYSIS; SEOUL VIRUS; SIN NOMBRE VIRUS;

AMINO ACID SEQUENCE; ANIMALS; ANTIBODIES, VIRAL; BIOLISTICS; CERCOPITHECUS AETHIOPS; COS CELLS; CROSS REACTIONS; DNA, COMPLEMENTARY; FEMALE; HANTAVIRUS; HANTAVIRUS INFECTIONS; MICE; MOLECULAR SEQUENCE DATA; NUCLEOCAPSID PROTEINS; SPECIES SPECIFICITY; VACCINES, DNA; VIRAL VACCINES;

EID: 33846256607     PISSN: 0264410X     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.vaccine.2006.09.082     Document Type: Article

References (40)

1. Lee H.W. Epidemiology and pathogenesis of hemorrhagic fever with renal syndrome. In: Elliott R.M. (Ed). The Bunyaviridae (1996), Plenum press, New York 253-267
2. Linderholm M., and Elgh F. Clinical characteristics of hantavirus infections on the Eurasian continent. Curr Top Microbiol Immunol 256 (2001) 135-151
3. Kruger D.H., Ulrich R., and Lundkvist A. Hantavirus infections and their prevention. Microbes Infect 3 (2001) 1129-1144
4. Schmaljohn C., and Hjelle B. Hantaviruses: a global disease problem. Emerg Infect Dis 3 (1997) 95-104
5. Plyusnin A., Nemirov K., Apekina N., Plyusina A., Lundkvist A., and Vaheri A. Dobrava hantavirus in Russia. Lancet 353 (1999) 207
6. Centers for Disease Control and Prevention, U.S. Department of Health and Human Services (http://www.cdc.gov/ncidod/diseases/hanta/hps/index.htm) and The Pan American Health Organization (PAHO) http://www.paho.org/common/Display.asp?Lang=E&RecID=1971.
7. Castillo C., Naranjo J., Sepulveda A., Ossa G., and Levy H. Hantavirus pulmonary syndrome due to Andes virus in Temuco, Chile: clinical experience with 16 adults. Chest 120 2 (2001) 548-554
8. Hooper J.M., Larsen T., Custer D.M., and Schmaljohn C.S. A lethal disease model for hantavirus pulmonary syndrome. Virology 289 1 (2001) 6-14
9. Padula P.J., Edelstein A., Miguel S.D., Lopez N.M., Rossi C.M., and Rabinovich R.D. Hantavirus pulmonary syndrome outbreak in Argentina: molecular evidence for person-to-person transmission of Andes virus. Virology 241 2 (1998) 323-330
10. Wells R.M., Sosa Estani S., Yadon Z.E., Enria D., Padula P., Pini N., et al. An unusual hantavirus outbreak in southern Argentina: person-to-person transmission? Hantavirus Pulmonary Syndrome Study Group for Patagonia. Emerg Infect Dis 3 2 (1997) 171-174
11. Toro J., Vega J.D., Khan A.S., Mills J.N., Padula P., Terry W., et al. An outbreak of hantavirus pulmonary syndrome, Chile, 1997. Emerg Infect Dis 4 4 (1998) 687-694
12. Plyusnin A. Genetics of hantaviruses: implications to taxonomy. Arch Virol 147 (2002) 665-682
13. Schmaljohn C.S. Molecular biology of hantaviruses. In: Elliot R.M. (Ed). The Bunyaviridae (1996), Plenum Press, New York 63-90
14. Vapalahti O., Kallio-Kokko H., Narvanen A., Julkunen I., Lundkvist A., Plyusnin A., et al. Human B-cell epitopes of Puumala virus nucleocapsid protein, the major antigen in early serological response. J Med Virol 46 4 (1995) 293-303
15. Kallio-Kokko H., Leveelahti R., Brummer-Korvenkontio M., Lundkvist A., Vaheri A., and Vapalahti O. Human immune response to Puumala virus glycoproteins and nucleocapsid protein expressed in mammalian cells. J Med Virol 65 3 (2001) 605-613
16. Elgh F., Lundkvist A., Alexeyev O.A., Wadell G., and Juto P. A major antigenic domain for the human humoral response to Puumala virus nucleocapsid protein is located at the amino-terminus. J Virol Methods 59 1-2 (1996) 161-172
17. Lundkvist A., Kallio-Kokko H., Sjölander K.B., Lankinen H., Niklasson B., Vaheri A., and Vapalahti O. Characterization of Puumala virus nucleocapsid protein: identification of B-cell epitopes and domains involved in protective immunity. Virology 216 2 (1996) 397-406
18. Yamada T., Hjelle B., Lanzi R., Morris C., Anderson B., and Jenison S. Antibody responses to Four Corners hantavirus infections in the deer mouse (Peromyscus maniculatus): identification of an immunodominant region of the viral nucleocapsid protein. J Virol 69 3 (1995) 1939-1943
19. Lundkvist A., Meisel H., Koletzki D., Lankinen H., Cifire F., Geldmacher A., et al. Mapping of B-cell epitopes in the nucleocapsid protein of Puumala hantavirus. Viral Immunol 15 1 (2002) 177-192
20. Elgh F., Linderholm M., Wadell G., Tärnvik A., and Juto P. Development of humoral cross-reactivity to the nucleocapsid protein of heterologous hantaviruses in nephropathia epidemica. FEMS Immunol Med Microbiol 22 (1998) 309-315
21. Hooper J.W., Custer D.M., Thompson E., and Schmaljohn C.S. DNA vaccination with the Hantaan virus M gene protects Hamsters against three of four HFRS hantaviruses and elicits a high-titer neutralizing antibody response in Rhesus monkeys. J Virol 75 18 (2001) 8469-8477
22. de Carvalho Nicacio C., Gonzalez Della Valle M., Padula P., Björling E., Plyusnin A., and Lundkvist A. Cross-protection against challenge with Puumala virus after immunization with nucleocapsid proteins from different hantaviruses. J Virol 76 13 (2002) 6669-6677
23. Chu Y.K., Jennings G., Schmaljohn A., Elgh F., Hjelle B., Lee H.W., et al. Cross-neutralization of hantaviruses with immune sera from experimentally infected animals and from hemorrhagic fever with renal syndrome and hantavirus pulmonary syndrome patients. J Infect Dis 172 6 (1995) 1581-1584
24. Sjölander K.B., and Lundkvist A. Dobrava virus infection: serological diagnosis and cross-reactions to other hantaviruses. J Virol Methods 80 2 (1999) 137-143
25. Garmory H.S., Perkins S.D., Phillpotts R.J., and Titball R.W. DNA vaccines for biodefence. Adv Drug Deliv Rev 57 9 (2005) 1343-1361
26. Woo G.J., Chun E.Y., Kim K.H., and Kim W. Analysis of immune responses against nucleocapsid protein of the Hantaan virus elicited by virus infection or DNA vaccination. J Microbiol 43 6 (2005) 537-545
27. Bucht G., Brus Sjölander K., Eriksson S., Lindgren L., Lundkvist A., and Elgh F. Modifying the cellular transport of DNA-based vaccines alters the immune response to hantavirus nucleocapsid protein. Vaccine 19 28-29 (2001) 3820-3829
28. Johansson P., Lindgren T., Lundström M., Holmström A., Elgh F., and Bucht G. PCR-generated linear DNA fragments utilized as a hantavirus DNA vaccine. Vaccine 20 27-28 (2002) 3379-3388
29. Johansson P., Olsson M., Lindgren L., Ahlm C., Elgh F., Holmström A., and Bucht G. Complete gene sequence of a human Puumala hantavirus isolate, Puumala Umeå/hu: sequence comparison and characterization of encoded gene products. Virus Res 105 2 (2004) 147-155
30. Chu G., Hayakawa H., and Berg P. Electroporation for the efficient transfection of mammalian cells with DNA. Nucl Acids Res 15 3 (1987) 1311-1326
31. Lole K.S., Bollinger R.C., Paranjape R.S., Gadkari D., Kulkarni S.S., Novak N.G., Ingersoll R., Sheppard H.W., and Ray S.C. Full-length human immunodeficiency virus type 1 genomes from subtype C-infected seroconverters in India, with evidence of intersubtype recombination. J Virol 73 1 (1999) 152-160
32. Saha S., Bhasin M., and Raghava G.P. Bcipep: a database of B-cell epitopes. BMC Genom 6 1 (2005) 79
33. Kolaskar A.S., and Tongaonkar P.C. A semi-empirical method for prediction of antigenic determinants on protein antigens. FEBS Lett 276 1-2 (1990) 172-174
34. Parker J.M., Guo D., and Hodges R.S. New hydrophilicity scale derived from high-performance liquid chromatography peptide retention data: correlation of predicted surface residues with antigenicity and X-ray-derived accessible sites. Biochemistry 25 19 (1986) 5425-5432
35. Jenison S., Yamada T., Morris C., Anderson B., Torres-Martinez N., Keller N., and Hjelle B. Characterization of human antibody responses to Four Corners Hantavirus infections among patients with hantavirus pulmonary syndrome. J Virol 68 5 (1994) 3000-3006
36. Lundkvist A., Björsten S., Niklasson B., and Ahlborg N. Mapping of B-cell determinants in the nucleocapsid protein of Puumala virus: definition of epitopes specific for acute immunoglobulin G recognition in humans. Clin Diagn Lab Immunol 2 1 (1995) 82-86
37. Yoshimatsu K., Arikawa J., Tamura M., Yoshida R., Lundkvist A., Niklasson B., Kariwa H., and Azuma I. Characterization of the nucleocapsid protein of Hantaan virus strain 76-118 using monoclonal antibodies. J Gen Virol 77 Pt 4 (1996) 695-704
38. Araki K., Yoshimatsu K., Ogino M., Ebihara H., Lundkvist A., Kariwa H., Takashima I., and Arikawa J. Truncated hantavirus nucleocapsid proteins for serotyping Hantaan, Seoul, and Dobrava hantavirus infections. J Clin Microbiol 39 7 (2001) 2397-2404
39. Morii M., Yoshimatsu K., Arikawa J., Zhou G., Kariwa H., and Takashima I. Antigenic characterization of Hantaan and Seoul virus nucleocapsid proteins expressed by recombinant baculovirus: application of a truncated protein, lacking an antigenic region common to the two viruses, as a serotyping antigen. J Clin Microbiol 36 9 (1998) 2514-2521
40. Wang M., Rossi C., and Schmaljohn C.S. Expression of non-conserved regions of the S genome segments of three hantaviruses: evaluation of the expressed polypeptides for diagnosis of haemorrhagic fever with renal syndrome. J Gen Virol 74 Pt 6 (1993) 1115-1124