Regulation of tylosin production: Role of a TylP-interactive ligand

Molecular Microbiology

Volumn 63, Issue 3, 2007, Pages 838-847

  Bignell, Dawn R D ^a,b   Bate, Neil ^a   Cundliffe, Eric ^a  

^a UNIVERSITY OF LEICESTER   (United Kingdom)

^b Department of Obstetrics Gynecology   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

GAMMA BUTYROLACTONE; HISTIDINE; ORGANIC SOLVENT; PROTEIN TYLP; PROTEIN TYLQ; PROTEIN TYLR; PROTEIN TYLS; RECEPTOR PROTEIN; TYLOSIN; UNCLASSIFIED DRUG;

ANTIMICROBIAL ACTIVITY; ARTICLE; BACTERIAL GENOME; BACTERIAL STRAIN; CONTROLLED STUDY; DNA SEQUENCE; GENE DISRUPTION; GENE INACTIVATION; NONHUMAN; OPEN READING FRAME; PRIORITY JOURNAL; PROMOTER REGION; PROTEIN BINDING; PROTEIN FUNCTION; PROTEIN SECRETION; PROTEIN SYNTHESIS; REGULATORY MECHANISM; STREPTOMYCES FRADIAE;

4-BUTYROLACTONE; BACTERIAL PROTEINS; DNA, BACTERIAL; DNA-BINDING PROTEINS; DOWN-REGULATION; ELECTROPHORETIC MOBILITY SHIFT ASSAY; GENE EXPRESSION REGULATION, BACTERIAL; LIGANDS; OPEN READING FRAMES; PROMOTER REGIONS (GENETICS); RECEPTORS, GABA-A; RECOMBINANT PROTEINS; REGULATORY ELEMENTS, TRANSCRIPTIONAL; STREPTOMYCES; TYLOSIN;

ACTINOBACTERIA (CLASS); STREPTOMYCES FRADIAE; STREPTOMYCES LIVIDANS;

EID: 33846255342     PISSN: 0950382X     EISSN: 13652958     Source Type: Journal    
DOI: 10.1111/j.1365-2958.2006.05541.x     Document Type: Article

References (31)

1. Bate, N., Butler, A.R., Gandecha, A.R., and Cundliffe, E. (1999) Multiple regulatory genes in the tylosin-biosynthetic cluster of Streptomyces fradiae. Chem Biol 6: 617-624.
2. Bate, N., Stratigopoulos, G., and Cundliffe, E. (2002) Differential roles of two SARP-encoding regulatory genes during tylosin biosynthesis. Mol Microbiol 43: 449-458.
3. Bate, N., Bignell, D.R.D., and Cundliffe, E. (2006) Regulation of tylosin biosynthesis involving 'SARP-helper' activity. Mol Microbiol 62: 148-156.
4. Bibb, M.J., White, J., Ward, J.M., and Janssen, G.R. (1994) The mRNA for the 23S rRNA methylase encoded by the ermE gene of Saccharopolyspora erythraea is translated in the absence of a conventional ribosome-binding site. Mol Microbiol 14: 533-545.
5. Blondelet-Rouault, M.-H., Weiser, J., Lebrihi, A., Branny, P., and Pernodet, J.-L. (1997) Antibiotic resistance cassettes derived from the Ω interposon for use in E. coli and Streptomyces. Gene 190: 315-317.
6. Butler, A.R., Bate, N., and Cundliffe, E. (1999) Impact of thioesterase activity on tylosin biosynthesis in Streptomyces fradiae. Chem Biol 6: 287-292.
7. Chater, K.F., and Chandra, G. (2006) The evolution of development in Streptomyces analysed by genome comparisons. FEMS Microbiol Rev 30: 651-672.
8. Choi, S.-U., Lee, C.-K., Hwang, Y.-I., Kinosita, H., and Nihira, T. (2003) γ-Butyrolactone autoregulators and receptor proteins in non-Streptomyces actinomycetes producing commercially important secondary metabolites. Arch Microbiol 180: 303-307.
9. Fishman, S.E., Cox, K., Larson, J.L., Reynolds, P.A., Seno, E.T., Yeh, W.-K., et al. (1987) Cloning genes for the biosynthesis of a macrolide antibiotic. Proc Natl Acad Sci USA 84: 8248-8252.
10. Flint, S.A., Stratigopoulos, G., Butler, A.R., and Cundliffe, E. (2002) Expression of tylM genes during tylosin production: Phantom promoters and enigmatic translational coupling motifs. J Ind Microbiol Biotechnol 28: 160-167.
11. Folcher, M., Gaillard, H., Nguyen, L.T., Nguyen, K.T., Lacroix, P., Bamas-Jacques, N., et al. (2001) Pleiotropic functions of a Streptomyces pristinaespiralis autoregulator receptor in development, antibiotic biosynthesis, and expression of a superoxide dismutase. J Biol Chem 276: 44297-44306.
12. Hara, O., and Beppu, T. (1982) Mutants blocked in streptomycin production in Streptomyces griseus - the role of A-factor. J Antibiot (Tokyo) 35: 349-358.
13. Hashimoto, K., Nihira, T., and Yamada, Y. (1992) Distribution of virginiae butanolides and IM-2 in the genus Streptomyces. J Ferment Bioeng 73: 61-65.
14. Hopwood, D.A., Bibb, M.J., Chater, K.F., Kieser, T., Bruton, C.J., Kieser, H.M., et al. (1985) Genetic Manipulation of Streptomyces. A Laboratory Manual. Norwich: The John Innes Foundation.
15. Horinouchi, S., and Beppu, T. (1992) Autoregulatory factors and communication in actinomycetes. Annu Rev Microbiol 46: 377-398.
16. Janssen, G.R., and Bibb, M.J. (1993) Derivatives of pUC18 that have BglII sites flanking a modified multiple cloning site and that retain the ability to identify recombinant clones by visual screening of Escherichia coli colonies. Gene 124: 133-134.
17. Kinoshita, H., Ipposhi, H., Okamoto, S., Nakano, H., Nihira, T., and Yamada, Y. (1997) Butyrolactone autoregulator receptor protein (BarA) as a transcriptional regulator in Streptomyces virginiae. J Bacteriol 179: 6986-6993.
18. Kinoshita, H., Tsuji, T., Ipposhi, H., Nihira, T., and Yamada, Y. (1999) Characterization of binding sequences for butyrolactone autoregulator receptors in streptomycetes. J Bacteriol 181: 5075-5080.
19. Ohashi, H., Zheng, Y.-H., Nihira, T., and Yamada, Y. (1989) Distribution of virginiae butanolides in antibiotic-producing actinomycetes, and identification of the inducing factor from Streptomyces antibioticus as virginiae butanolide A. J Antibiot 42: 1191-1195.
20. Ohnishi, Y., Yamazaki, H., Kato, J.-Y., Tomono, A., and Horinouchi, S. (2005) AdpA, a central transcriptional regulator in the A-factor regulatory cascade that leads to morphological development and secondary metabolism in Streptomyces griseus. Biosci Biotechnol Biochem 69: 431-439.
21. Onaka, H., Ando, N., Nihira, T., Yamada, Y., Beppu, T., and Horinouchi, S. (1995) Cloning and characterization of the A-factor receptor gene from Streptomyces griseus. J Bacteriol 177: 6083-6092.
22. Ramos, J.L., Martínez-Bueno, M., Molina-Henares, A.J., Terán, W., Watanabe, K., Zhang, X., et al. (2005) The TetR family of transcriptional repressors. Microbiol Mol Biol Rev 69: 326-356.
23. Sambrook, J., Fritsch, E.F., and Maniatis, T. (1989) Molecular Cloning. A Laboratory Manual, 2nd edn. Cold Spring Harbor, NY: Cold Spring Harbor Laboratory Press.
24. Shikura, N., Yamamura, J., and Nihira, T. (2002) barS1, a gene for biosynthesis of a γ-butyrolactone autoregulator, a microbial signaling molecule eliciting antibiotic production in Streptomyces species. J Bacteriol 184: 5151-5157.
25. Stratigopoulos, G., and Cundliffe, E. (2002) Expression analysis of the tylosin-biosynthetic gene cluster: pivotal regulatory role of the tylQ product. Chem Biol 9: 71-78.
26. Stratigopoulos, G., Gandecha, A.R., and Cundliffe, E. (2002) Regulation of tylosin production and morphological differentiation in Streptomyces fradiae by TylP, a deduced γ-butyrolactone receptor. Mol Microbiol 45: 735-744.
27. Stratigopoulos, G., Bate, N., and Cundliffe, E. (2004) Positive control of tylosin biosynthesis: pivotal role of TylR. Mol Microbiol 54: 1326-1334.
28. Takano, E. (2006) γ-Butyrolactones: Streptomyces signalling molecules regulating antibiotic production and differentiation. Curr Opin Microbiol 9: 1-8.
29. Takano, E., Chakraburtty, R., Nihira, T., Yamada, Y., and Bibb, M.J. (2001) A complex role for the γ-butyrolactone SCB1 in regulating antibiotic production in Streptomyces coelicolor A3(2). Mol Microbiol 41: 1015-1028.
30. Waki, M., Nihira, T., and Yamada, Y. (1997) Cloning and characterization of the gene (farA) encoding the receptor for an extracellular regulatory factor (IM-2) from Streptomyces sp. strain FRI-5. J Bacteriol 179: 5131-5137.
31. Yamada, Y. (1999) Autoregulatory factors and regulation of antibiotic production in Streptomyces. In Microbial Signalling and Communication. England, R.R., Hobbs, G., Bainton, N.J., and Roberts, D.McL. (eds). Cambridge, UK: Society for General Microbiology Cambridge University Press, pp. 177-196.