Thermal stability of the WHO international standard of interferon alpha 2b (IFN-α2b): Application of new reporter gene assay for IFN-α2b potency determinations

Journal of Immunological Methods

Volumn 319, Issue 1-2, 2007, Pages 6-12

  Caserman, Simon ^a   Menart, Viktor ^a   Gaines Das, Rose ^b   Williams, Stella ^b   Meager, Anthony ^b  

^a NATIONAL INSTITUTE OF CHEMISTRY   (Slovenia)

^b NATIONAL INSTITUTE FOR BIOLOGICAL STANDARDS AND CONTROL   (United Kingdom)

Author keywords

Bioassays; Interferon 2b; Reporter gene; Thermal stability

Indexed keywords

ALPHA2B INTERFERON;

ABSORPTION; AMPOULE; ANTIVIRAL ACTIVITY; ARTICLE; CHEMICAL STRUCTURE; COMPARATIVE STUDY; CONCENTRATION PROCESS; CONTROLLED STUDY; DILUTION; DRUG POTENCY; ENZYME KINETICS; ENZYME RELEASE; FREEZE DRYING; HIGH TEMPERATURE; HIGH THROUGHPUT SCREENING; HUMAN; HUMAN CELL; IMMUNOASSAY; IMMUNOLOGICAL PROCEDURES; LOW TEMPERATURE; PRIORITY JOURNAL; REPORTER GENE ASSAY; SAMPLE; STANDARD; STORAGE TEMPERATURE; THERMOSTABILITY; WORLD HEALTH ORGANIZATION;

CELL LINE, TUMOR; DOSE-RESPONSE RELATIONSHIP, DRUG; DRUG STABILITY; GENES, REPORTER; HEAT; HUMANS; IMMUNOLOGIC TESTS; INTERFERON ALFA-2B; KINETICS; PREDICTIVE VALUE OF TESTS; REFERENCE STANDARDS; WORLD HEALTH ORGANIZATION;

EID: 33846254544     PISSN: 00221759     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.jim.2006.11.006     Document Type: Article

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