A method for predicting hopper flow characteristics of pharmaceutical powders

Chemical Engineering Science

Volumn 62, Issue 5, 2007, Pages 1536-1542

  Faqih, AbdulMobeen N ^a   Alexander, Albert W ^b   Muzzio, Fernando J ^a   Tomassone, M Silvina ^a  

^a The State University of New Jersey   (United States)

^b ASTRAZENECA   (United Kingdom)

Author keywords

Cohesion; Granular; Hopper; Materials; Particle; Powder technology

Indexed keywords

CORRELATION METHODS; DRUG PRODUCTS; FLOW PATTERNS; GRANULAR MATERIALS; RHEOMETERS;

COHESION; GRAVITATIONAL DISPLACEMENT RHEOMETER (GDR); HOPPER FLOW; POWDER TECHNOLOGY;

FLOW OF SOLIDS;

CORRELATION METHODS; DRUG PRODUCTS; FLOW OF SOLIDS; FLOW PATTERNS; GRANULAR MATERIALS; RHEOMETERS;

EID: 33846236513     PISSN: 00092509     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.ces.2006.06.027     Document Type: Article

References (19)

1. Baxter J., Abouchakra H., Tuzun U., and Lamptey B.M. A DEM simulation and experimental strategy for solving fine powder flow problems. Transactions of the Institution of Chemical Engineers 78 (2000) 1019-1025
2. Carr R.L. Evaluating flow properties of solids. Chemical Engineering 18 (1965) 163-168
3. Davidson J.F., and Nedderman R.M. Transaction of the Institution of Chemical Engineers 51 (1973) 29
4. Faqih A., Chaudhuri B., Alexander A., Muzzio F.J., and Tomassone MS. An experimental/computational approach for examining unconfined cohesive powder flow. Internal Journal of Pharmaceutics 324 2 (2006) 116-127
5. Hausner H. Friction conditions in a mass of metal powder. International Journal of Powder Metallurgy 3 (1967) 7
6. Jenike, A.W., 1964. Storage and Flow of Solids, Bulletin 123, Engineering Experiment Station, University of Utah.
7. Johanson J.R. Bulk Solids Handling 12 (1978) 237-240
8. Johanson, J.R., 1993. Reliable Flow of Particulate Solids II, Oslo, pp. 11-32.
9. Kaye B.H., Gratton-Liimatainen J., and Lloyd J. The effect of flow agents on the rheology of a plastic powder. Particle & Particle Systems Characterization 12 (1995) 194-197
10. Knowlten T., et al. The importance of storage, transfer and collection. Chemical Engineering Progress 90 (1994) 44-54
11. Maltby L.P., and Enstad G.G. Bulk Solids Handling 13 (1993) 135
12. Maltby, L.P, 1993. Dissertation, Telemark Institute of Technology, Porsgrunn, Norway.
13. Molerus O., and Nywelt M. The influence of the fine particle content on the flow behavior of bulk materials. Powder Technology 37 (1984) 145-154
14. Peleg M. Flowability of food powders and methods for its evaluation-a review. Journal of Food Process Engineering 1 (1978) 303-328
15. Purutyan, H., Pittenger, B.H., Carson, J.W., 1998. Solve solids handling problems by retrofitting. Chemical Engineering Progress, 27-39.
16. Raymond, R., Sheskey, P, Weller, P.J., 2005. Handbook of Pharmaceutical Sciences, second ed. The Pharmaceutical Press, London, p. 141.
17. Staniforth J., 2002. In: M.E. Aulton (Ed.), Pharmaceutics, second ed. Churchill Livingstone, New York, p. 197.
18. Savage S.B. The mass flow of granular material derived from coupled velocity-stress fields. British Journal of Applied Physics 16 (1965) 1885-1888
19. Schulze, D., 1994. First Particle Technology Forum, vol. 3, Denver, USA, pp. 11-16.