Incidence of and factors associated with hepatocellular carcinoma among hepatitis C virus and human immunodeficiency virus coinfected patients with decompensated cirrhosis

AIDS Research and Human Retroviruses

Volumn 22, Issue 12, 2006, Pages 1236-1241

  García García, José A ^a   Romero Gómez, Manuel ^a   Girón González, José A ^b   Rivera Irigoin, Robin ^b   Torre Cisneros, Julián ^c   Montero, José L ^c   González Serrano, Mercedes ^d   Andrade, Raúl J ^d   Aguilar Guisado, Manuela ^e   Grilo, Israel ^e   Martín Vivaldi, Javier ^f   Salmerón, Javier ^g   Caballero Granado, Francisco J ^h   Macías, Juan ^a   Vergara López, Salvador ^a   Pineda, Juan A ^a  

^a HOSPITAL UNIVERSITARIO DE VALME   (Spain)

^b HOSPITAL UNIVERSITARIO PUERTA DEL MAR   (Spain)

^c HOSPITAL UNIVERSITARIO REINA SOFÍA   (Spain)

^d HOSPITAL UNIVERSITARIO VIRGEN DE LA VICTORIA   (Spain)

^e HOSPITAL UNIVERSITARIO VIRGEN DEL ROCÍO   (Spain)

^f HOSPITAL COSTA DEL SOL   (Spain)

^g HOSPITAL UNIVERSITARIO SAN CECILIO   (Spain)

^h HOSPITAL PUNTA DE EUROPA   (Spain)

Author keywords

[No Author keywords available]

Indexed keywords

ALANINE AMINOTRANSFERASE; ANTIRETROVIRUS AGENT; INTERFERON;

ADULT; AGED; ALANINE AMINOTRANSFERASE BLOOD LEVEL; ARTICLE; CANCER INCIDENCE; COHORT ANALYSIS; CONTROLLED STUDY; FEMALE; HEPATITIS C; HIGHLY ACTIVE ANTIRETROVIRAL THERAPY; HUMAN; HUMAN IMMUNODEFICIENCY VIRUS INFECTED PATIENT; HUMAN IMMUNODEFICIENCY VIRUS INFECTION; LIVER CELL CARCINOMA; LIVER CIRRHOSIS; MAJOR CLINICAL STUDY; MALE; PRIORITY JOURNAL; RETROSPECTIVE STUDY; SPAIN; SUPERINFECTION; SURVIVAL;

AGED; CARCINOMA, HEPATOCELLULAR; COHORT STUDIES; FEMALE; HEPATITIS C, CHRONIC; HIV INFECTIONS; HUMANS; LIVER CIRRHOSIS; LIVER NEOPLASMS; MALE; MIDDLE AGED; RETROSPECTIVE STUDIES; RISK FACTORS; SPAIN;

EID: 33846226509     PISSN: 08892229     EISSN: None     Source Type: Journal    
DOI: 10.1089/aid.2006.22.1236     Document Type: Article

References (21)

1. Macías J, Melguizo I, Ferńndez Rivera J, et al.: Mortality due to liver failure and impact on survival of hepatitis C virus infection in HIV-infected patients receiving potent antiretroviral therapy. Eur J Clin Microbiol Infect Dis 2002;21:775-781.
2. Di Martino V, Rufat P, Boyer N, et al.: The influence of human immunodeficiency virus coinfection on chronic hepatitis C in injection drug users: A long-term retrospective cohort study. Hepatolo 2001;4:1193-1199.
3. Eyster ME, Diamondstone LS, Lien JM, Ehman WC, Quan S, and Goedert JJ: Natural history of hepatitis C virus infection in multitransfused hemophiliacs: Effect of coinfection with human immunodeficiency virus. The multicenter hemophilia cohort study. J Acquir Immune Defic Syndr 1993;6:602-610.
4. Darby SC, Ewart DW, Giangrande PL, et al.: Mortality from liver cancer and liver disease in haemophilic men and boys in UK given blood products contaminated with hepatitis C. Lancet 1997;350:1425-1431.
5. Ragni MV and Belle SH: Impact of human immunodeficiency virus infection on progression to end-stage liver disease in individuals with hemophilia and hepatitis C virus infection. J Infect Dis 2001;183:1112-1115.
6. Goedert JJ, Eyster ME, Lederman MM, et al.: End-stage liver disease in persons with hemophilia and transfusion-associated infections. Blood 2002;100:1584-1589.
7. Llovet JM: Viral hepatitis and hepatocellular carcinoma. Hepatol Rev 2004;1:89-98.
8. García-Samaniego J, Rodríguez M, Berenguer J, et al.: Hepatocellular carcinoma in HIV-infected patients with chronic hepatitis C. Am J Gastroenterol 2001;96:3441-3442.
9. Puoti M, Bruno R, Soriano V, et al.: Hepatocellular carcinoma in HIV-infected patients: Epidemiological features, clinical presentation and outcome. AIDS 2004;18:2285-2293.
10. Smukler AJ and Ratner L: Hepatitis viruses and hepatocellular in HIV-infected patients. Curr Opin Oncol 2002;14:657-679.
11. Kramer JR, Giordano TP, Souchek J, Richardson P, Hwang L, and El-Serag HB: The effect of HIV coinfection on the risk of cirrhosis and hepatocellular carcinoma in U.S. veterans with hepatitis C. Am J Gastroenterol 2005;100:56-63.
12. Pineda JA, Romero-Gómez M, Díaz F, et al.: HIV coinfection shortens the survival of patients with hepatitis C virus-related decompensated cirrhosis. Hepatology 2005;41:779-789.
13. Bruix J, Sherman M, Lovet JM, et al.: Clinical management of hepatocellular carcinoma. Conclusions of the Barcelona-2000 EASL Conference. J Hepatol 2001;35:421-430.
14. Castells L, Vargas V, González A, Esteban J, Esteban R, and Guardia J: Long interval between HCV infection and development of hepatocellular carcinoma. Liver 1995;15:159-163.
15. Qurishi N, Kreuzberg C, Luchters G, et al.: Effect of antiretroviral therapy on liver-related mortality in patients with HIV and hepatitis C virus coinfection. Lancet 2003;362:1708-1713.
16. Rosenthal E, Poiree M, Pradier C, et al.: Mortality due to hepatitis C-related liver disease in HIV-infected patients in France (Mortavic 2001 study). AIDS 2003;17:1803-1809.
17. Macías J, Japón MA, Sáez C, et al.: Increased hepatocyte Fas expression and apoptosis in human immunodeficiency virus and hepatitis C virus coinfection. J Infect Dis 2005;192:1566-1576.
18. Munshi N, Balasubramanian A, Koziel M, Ganju RK, and Groopman JE: Hepatitis C and human immunodeficiency virus envelope proteins cooperatively induce hepatocytic apoptosis via an innocent bystander mechanism. J Infect Dis 2003;188:1192-1204.
19. Sato A, Kato Y, Nakata K, et al.: Relationship between sustained elevation of serum alanine aminotransferase and progression from cirrhosis to hepatocellular carcinoma: Comparison in patients with hepatitis B virus- and hepatitis C virus-associated cirrhosis. J Gastroenterol Hepatol 1996;11:944-948.
20. Tarao K, Rino Y, Ohkawa S, et al.: Close association between high serum alanine aminotransferase levels and multicentric hepatocarcinogenesis in patients with hepatitis C virus-associated cirrhosis. Cancer 2002;94:1787-1795.
21. Shiratori Y, Ito Y, Yokosuka O, et al.: Antiviral therapy for cirrhotic hepatitis C: Association with reduced hepatocellular carcinoma development and improved survival. Ann Intern Med 2005;142:105-114.