Morphology control of polylactide microspheres enclosing irinotecan hydrochloride with polylactide based polymer surfactant for reduction of initial burst

International Journal of Pharmaceutics

Volumn 330, Issue 1-2, 2007, Pages 32-36

  Nishino, Satoru ^a   Kishida, Akio ^b   Yoshizawa, Hidekazu ^c  

^a NARA NATIONAL COLLEGE OF TECHNOLOGY   (Japan)

^b TOKYO MEDICAL AND DENTAL UNIVERSITY   (Japan)

^c Graduate School of Medicine   (Japan)

Author keywords

Antitumor agent; Microparticulate drug delivery system; Polylactide; Polymer microspheres; Surface morphology

Indexed keywords

IRINOTECAN; MICROSPHERE; POLYETHYLENE OXIDE OLEATE; POLYLACTIDE; POLYMER; SURFACTANT; UNCLASSIFIED DRUG;

ARTICLE; BIODEGRADABILITY; CONTROLLED DRUG RELEASE; DIFFERENTIAL SCANNING CALORIMETRY; DRUG DELIVERY SYSTEM; EMULSION; EVAPORATION; MISCIBILITY; MORPHOLOGY; PRIORITY JOURNAL; SURFACE PROPERTY;

ANTINEOPLASTIC AGENTS; CALORIMETRY, DIFFERENTIAL SCANNING; CAMPTOTHECIN; DELAYED-ACTION PREPARATIONS; DRUG DELIVERY SYSTEMS; MICROSCOPY, ELECTRON, SCANNING; MICROSPHERES; POLYESTERS; POLYETHYLENE GLYCOLS;

EID: 33846219544     PISSN: 03785173     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.ijpharm.2006.08.035     Document Type: Article

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