Performance profile of sodium hyaluronate in patients with lipid tear deficiency: Randomised, double-blind, controlled, exploratory study

British Journal of Ophthalmology

Volumn 91, Issue 1, 2007, Pages 47-50

  Prabhasawat, P ^a   Tesavibul, N ^a   Kasetsuwan, N ^a  

^a MAHIDOL UNIVERSITY   (Thailand)

Author keywords

[No Author keywords available]

Indexed keywords

DEXTRAN; HYALURONIC ACID; HYDROXYPROPYLMETHYLCELLULOSE; TEAR PROTEIN;

ADULT; AGED; ARTICLE; CLINICAL ARTICLE; CLINICAL ASSESSMENT; CLINICAL TRIAL; CONTROLLED CLINICAL TRIAL; CONTROLLED STUDY; DOUBLE BLIND PROCEDURE; DRY EYE; FEMALE; HUMAN; LACRIMAL FLUID; LACRIMATION DISORDER; LIPID TEAR DEFICIENCY; MALE; PRIORITY JOURNAL; RANDOMIZED CONTROLLED TRIAL;

ADULT; AGED; DOUBLE-BLIND METHOD; DRY EYE SYNDROMES; FEMALE; HUMANS; HYALURONIC ACID; LIPIDS; MALE; METHYLCELLULOSE; MIDDLE AGED; OPHTHALMIC SOLUTIONS; TEARS; TREATMENT OUTCOME;

EID: 33846201565     PISSN: 00071161     EISSN: None     Source Type: Journal    
DOI: 10.1136/bjo.2006.097691     Document Type: Article

References (28)

1. Lemp MA. Report of the National Eye Institute/Industry Workshop on clinical trials in dry eyes. CLAO J 1995;21:221-32.
2. Djalilian AR, Hamrah P, Pflugfelder SC. In: Krashmer JH, Mannis MJ, Holland EJ, eds. Cornea, 2nd edn. Philadelphia: Elsevier, 2005:521-40.
3. Aragona P, Di Stefano G, Ferreri F, et al. Sodium hyaluronate eye drops of different osmolarity for the treatment of dry eye in Sjogren's syndrome patients. Br J Ophthalmol 2002;86:879-84.
4. Aragona P, Papa V, Micali A, et al. Long term treatment with sodium hyaluronate-containing artificial tears reduces ocular surface damage in patients with dry eye. Br J Ophthalmol 2002;86:181-4.
5. Brignole F, Pisella PJ, Dupas B, et al. Efficacy and safety of 0.18% sodium hyaluronate in patients with moderate dry eye syndrome and superficial keratitis. Graefes Arch Clin Exp Ophthalmol 2005;243:531-8.
6. Lee S-H, Tseng SCG. Rose Bengal staining and cytologic characteristics associated with lipid tear deficiency. Am J Ophthalmol 1997;124:736-50.
7. McMonnies CW. Key questions in a dry eye history. J Am Optom Assoc 1986;57:512-17.
8. McMonnies CW, Ho A. Patient history in screening for dry eye conditions. J Am Optom Assoc 1987;58:296-301.
9. Bijsterveld OP. Diagnostic tests in the Sicca syndrome. Arch Ophthalmol 1969;82:10-14.
10. Guillon JP. The Keeler Tearscope-Plus - an improved device for assessing the tear film. Optician 1997;213:1-4.
11. Guillon M, Guillon J. Tear film examination of contact lens patient. Optician 1993;206:21-9.
12. Rolando M, Refojo MF, Kenyon KR. Tear water evaporation and eye surface diseases. Ophthalmologica 1985;190:147-9.
13. Zengin N, Tol H, Gunduz K, et al. Meibomian gland dysfunction tear film abnormalities in rosacea. Cornea 1995;14:144-6.
14. Goto E, Tseng SC. Differentiation of lipid tear deficiency dry eye by kinetic analysis of tear interference images. Arch Ophthalmol 2003;121:173-80.
15. Mengher LS, Pandher KS, Bron AJ, et al. Effect of sodium hyaluronate (0.1%) on break-up time (NIBUT) in patients with dry eyes. Br J Ophthalmol 1986;70:442-7.
16. Mengher LS, Bron AJ, Tonge SR, et al. A non-invasive instrument for clinical assessment of the precorneal tear film stability. Curr Eye Res 1985;4:1-7.
17. Golding TR, Efron N, Brennan NA. Soft lens lubricants and prelens tear film stability. Optom Vis Sci 1990;67:461-5.
18. Condon PI, McEwen CG, Wright M, et al. Double blind, randomised, placebo controlled, crossover, multicentre study to determine the efficacy of a 0.1% (w/v) sodium hyaluronate solution (Fermavisc) in the treatment of dry eye syndrome. Br J Ophthalmol 1999;83:1121-4.
19. Johnson ME, Murphy PJ, Boulton M. Effectiveness of sodium hyaluronate eyedrops in the treatment of dry eye. Graefes Arch Clin Exp Ophthalmol 2005;28:1-4.
20. Tiffany JM. Viscoelastic properties of human tears and polymer solutions. Adv Exp Med Biol 1994;350:267-70.
21. Tiffany JM, Winter N, Bliss G. Tear film stability and tear surface tension. Curr Eye Res 1989;8:507-15.
22. Nakamura M, Hikida M, Nakano T, et al. Characterization of water retentive properties of hyluronan. Cornea 1993;12:433-6.
23. Mathers WD, Binarao G, Petroll M. Ocular water evaporation and the dry eye. A new measuring device. Cornea 1993;12:335-40.
24. Mothers WD. Ocular evaporation in meibomian gland dysfunction and dry eye. Ophthalmology 1993;347:51-100.
25. Mathers WD. Meibomian gland morphology and tear osmolarity: changes with Accutane therapy. Cornea 1991;10:286-90.
26. Goto E, Shimazaki J, Monden Y, et al. Low-concentration homogenized castor oil eye drops for noninflamed obstructive meibomian gland dysfunction. Ophthalmology 2002;109:2030-5.
27. Di Pascuale MA, Goto E, Tseng SCG. Sequential changes of lipid tear film after the instillation of a single drop of a new emulsion eye drop in dry eye patients. Ophthalmology 2004;111:783-91.
28. Korb DR, Scaffidi RC, Greiner JV, et al. The effect of two novel lubricant eye drops on tear film lipid layer thickness in subjects with dry eye symptoms. Optom Vis Sci 2005;28:594-601.