Cardiac sympathetic afferent stimulation augments the arterial chemoreceptor reflex in anesthetized rats

Journal of Applied Physiology

Volumn 102, Issue 1, 2007, Pages 37-43

  Gao, Lie ^a   Pan, Yan Xia ^a   Wang, Wei Zhong ^a   Li, Yu Long ^a   Schultz, Harold D ^a   Zucker, Irving H ^a   Wang, Wei ^a,b  

^a UNIVERSITY OF NEBRASKA MEDICAL CENTER   (United States)

^b NEBRASKA MEDICAL CENTER   (United States)

Author keywords

AT1 receptor; Cardiac sympathetic afferent reflex; Mean arterial pressure; Renal sympathetic nerve activity

Indexed keywords

ANGIOTENSIN 1 RECEPTOR; ANGIOTENSIN II; CAPSAICIN; LOSARTAN; NICOTINE; POTASSIUM CYANIDE;

ANIMAL EXPERIMENT; ARTICLE; CHEMORECEPTOR REFLEX; CONTROLLED STUDY; ELECTROSTIMULATION; HEART RATE; MALE; MEAN ARTERIAL PRESSURE; NONHUMAN; PRESSOR RESPONSE; PRIORITY JOURNAL; SOLITARY TRACT NUCLEUS; SYMPATHETIC NERVE; SYMPATHETIC REFLEX;

ANALGESICS, NON-NARCOTIC; ANGIOTENSIN II; ANGIOTENSIN II TYPE 1 RECEPTOR BLOCKERS; ANIMALS; ARTERIES; BLOOD PRESSURE; CAPSAICIN; CARDIOVASCULAR PHYSIOLOGY; CARDIOVASCULAR SYSTEM; CHEMORECEPTORS; ELECTRIC STIMULATION; LOSARTAN; MALE; NEURONS, AFFERENT; NICOTINE; POTASSIUM CYANIDE; RATS; RATS, SPRAGUE-DAWLEY; RECEPTOR, ANGIOTENSIN, TYPE 1; SOLITARY NUCLEUS; SYMPATHETIC NERVOUS SYSTEM; UNCONSCIOUSNESS;

EID: 33846157222     PISSN: 87507587     EISSN: 15221601     Source Type: Journal    
DOI: 10.1152/japplphysiol.00681.2006     Document Type: Article

References (35)

1. Bishop VS, Malliani A, Thoren P. Cardiac mechanoreceptors. In: Handbook of Physiology. The Cardiovascular System. Peripheral Circulation and Organ Blood Flow. Bethesda, MD: Am. Physiol. Soc., 1983, sect. 2, vol. III, pt. 2, chapt. 15, p. 497-556.
2. Brown AM. Excitation of afferent cardiac sympathetic nerve fibres during myocardial ischaemia. J Physiol 190: 35-53, 1967.
3. Casto R, Phillips MI. Angiotensin II attenuates baroreflexes at nucleus tractus solitarius of rats. Am J Physiol Regul Integr Comp Physiol 250: R193-R198, 1986.
4. Chen Y, Chen H, Hoffmann A, Cool DR, Diz DI, Chappell MC, Chen AF, Morris M. Adenovirus-mediated small-interference RNA for in vivo silencing of angiotensin AT1a receptors in mouse brain. Hypertension 47: 230-237, 2006.
5. Cohn JN, Levine TB, Olivari MT, Garberg V, Lura D, Francis GS, Simon AB, Rector T. Plasma norepinephrine as a guide to prognosis in patients with chronic congestive heart failure. N Engl J Med 311: 819-823, 1984.
6. Floras JS. Clinical aspects of sympathetic activation and parasympathetic withdrawal in heart failure. J Am Coll Cardiol 22: 72A-84A, 1993.
7. Franchini KG, Krieger EM. Cardiovascular responses of conscious rats to carotid body chemoreceptor stimulation by intravenous KCN. J Auton Nerv Syst 42: 63-69, 1993.
8. Francis GS, Goldsmith SR, Levine TB, Olivari MT, Cohn JN. The neurohumoral axis in congestive heart failure. Ann Intern Med 101: 370-377, 1984.
9. Gao L, Schultz HD, Patel KP, Zucker IH, Wang W. Augmented input from cardiac sympathetic afferents inhibits baroreflex in rats with heart failure. Hypertension 45: 1173-1181, 2005.
10. Gao L, Zhu Z, Zucker IH, Wang W. Cardiac sympathetic afferent stimulation impairs baroreflex control of renal sympathetic nerve activity in rats. Am J Physiol Heart Circ Physiol 286: H1706-H1711, 2004.
11. Hilton SM. Hypothalamic regulation of the cardiovascular system. Br Med Bull 22: 243-248, 1966.
12. Kasparov S, Butcher JW, Paton JF. Angiotensin II receptors within the nucleus of the solitary tract mediate the developmental attenuation of the baroreceptor vagal reflex in pre-weaned rats. J Auton Nerv Syst 74: 160-168, 1998.
13. Korner PI. Integrative neural cardiovascular control. Physiol Rev 51: 312-367, 1971.
14. Luoh HF, Chan SH. Participation of AT1 and AT2 receptor subtypes in the tonic inhibitory modulation of baroreceptor reflex response by endogenous angiotensins at the nucleus tractus solitarii in the rat. Brain Res 782: 73-82, 1998.
15. Ma R, Schultz HD, Wang W. Chronic central infusion of ANG II potentiates cardiac sympathetic afferent reflex in dogs. Am J Physiol Heart Circ Physiol 277: H15-H22, 1999.
16. Ma R, Zucker IH, Wang W. Central gain of the cardiac sympathetic afferent reflex in dogs with heart failure. Am J Physiol Heart Circ Physiol 273: H2664-H2671, 1997.
17. Machado BH, Mauad H, Chianca Junior DA, Haibara AS, Colombari E. Autonomic processing of the cardiovascular reflexes in the nucleus tractus solitarii. Braz J Med Biol Res 30: 533-543, 1997.
18. Mancia G. Influence of carotid baroreceptors on vascular responses to carotid chemoreceptor stimulation in the dog. Circ Res 36: 270-276, 1975.
19. Mancia G, Seravalle G, Giannattasio C, Bossi M, Preti L, Cattaneo BM, Grassi G. Reflex cardiovascular control in congestive heart failure. Am J Cardiol 69: 17G-22G, 1992.
20. Michelini LC, Bonagamba LG. Angiotensin II as a modulator of baroreceptor reflexes in the brainstem of conscious rats. Hypertension 15: I45-I50, 1990.
21. Mifflin SW. Arterial chemoreceptor input to nucleus tractus solitarius. Am J Physiol Regul Integr Comp Physiol 263: R368-R375, 1992.
22. Pagani M, Pizzinelli P, Furlan R, Guzzetti S, Rimoldi O, Sandrone G, Malliani A. Analysis of the pressor sympathetic reflex produced by intracoronary injections of bradykinin in conscious dogs. Circ Res 56: 175-183, 1985.
23. Paxinos G, Watson C. The Rat Brain in Stereotaxic Coordinates. Orlando, FL: Academic, 1986.
24. Pisarri TE, Kendrick JE. Reduced effectiveness of the carotid baroreflex during arterial hypoxia in dogs. Am J Physiol Heart Circ Physiol 247: H623-H630, 1984.
25. Ponikowski P, Chua TP, Piepoli M, Ondusova D, Webb-Peploe K, Harrington D, Anker SD, Volterrani M, Colombo R, Mazzuero G, Giordano A, Coats AJ. Augmented peripheral chemosensitivity as a potential input to baroreflex impairment and autonomic imbalance in chronic heart failure. Circulation 96: 2586-2594, 1997.
26. Rosario LB, Rocha I, and Silva-Carvalho L. Effect of losartan micro-injections into the NTS on the cardiovascular components of chemically evoked reflexes in a rabbit model of acute heart ischemia. Adv Exp Med Biol 536: 423-431, 2003.
27. Somers VK, Mark AL, Abboud FM. Interaction of baroreceptor and chemoreceptor reflex control of sympathetic nerve activity in normal humans. J Clin Invest 87: 1953-1957, 1991.
28. Sun SY, Wang W, Zucker IH, Schultz HD. Enhanced activity of carotid body chemoreceptors in rabbits with heart failure: role of nitric oxide. J Appl Physiol 86: 1273-1282, 1999.
29. Sun SY, Wang W, Zucker IH, Schultz HD. Enhanced peripheral chemoreflex function in conscious rabbits with pacing-induced heart failure. J Appl Physiol 86: 1264-1272, 1999.
30. Tjen AL, Bonham A, Longhurst J. Interactions between sympathetic and vagal cardiac afferents in nucleus tractus solitarii. Am J Physiol Heart Circ Physiol 272: H2843-H2851, 1997.
31. Uchida Y, Murao S. Effect of propranolol on excitation of afferent sympathetic nerve fibers during myocardial ischemia. Jpn Heart J 15: 280-288, 1974.
32. Uchida Y, Murao S. Excitation of afferent cardiac sympathetic nerve fibers during coronary occlusion. Am J Physiol 226: 1094-1099, 1974.
33. Wang W, Ma R. Cardiac sympathetic afferent reflexes in heart failure. Heart Failure Rev 5: 57-71, 2002.
34. Wang W, Zucker IH. Cardiac sympathetic afferent reflex in dogs with congestive heart failure. Am J Physiol Regul Integr Comp Physiol 271: R751-R756, 1996.
35. Zhu GQ, Zucker IH, Wang W. Central AT1 receptors are involved in the enhanced cardiac sympathetic afferent reflex in rats with chronic heart failure. Basic Res Cardiol 97: 320-326, 2002.