Acute caffeine ingestion does not impair glucose tolerance in persons with tetraplegia

Journal of Applied Physiology

Volumn 102, Issue 1, 2007, Pages 374-381

  Battram, D S ^a   Bugaresti, J ^b   Gusba, J ^a   Graham, T E ^a  

^a UNIVERSITY OF GUELPH   (Canada)

^b HAMILTON HEALTH SCIENCES   (Canada)

Author keywords

Adenosine receptor antagonist; Insulin resistance; Spinal cord injury; Type 2 diabetes

Indexed keywords

ADRENALIN; C PEPTIDE; CAFFEINE; GELATIN; GLUCOSE; GLYCEROL; INSULIN; PROINSULIN;

ADULT; ARTICLE; BLOOD SAMPLING; CLINICAL ARTICLE; CLINICAL TRIAL; CONTROLLED CLINICAL TRIAL; CONTROLLED STUDY; DRUG BLOOD LEVEL; DRUG CAPSULE; GLUCOSE BLOOD LEVEL; GLUCOSE INTOLERANCE; GLYCEROL BLOOD LEVEL; HUMAN; INSULIN BLOOD LEVEL; INSULIN RESPONSE; ORAL GLUCOSE TOLERANCE TEST; PRIORITY JOURNAL; QUADRIPLEGIA; RANDOMIZED CONTROLLED TRIAL; SINGLE BLIND PROCEDURE;

ADMINISTRATION, ORAL; ADULT; BLOOD GLUCOSE; BLOOD PRESSURE; C-PEPTIDE; CAFFEINE; DOSE-RESPONSE RELATIONSHIP, DRUG; EPINEPHRINE; GLUCAGON-LIKE PEPTIDE 1; GLUCOSE TOLERANCE TEST; GLYCEROL; HEART RATE; HUMANS; INSULIN; MIDDLE AGED; QUADRIPLEGIA; SINGLE-BLIND METHOD;

EID: 33846148358     PISSN: 87507587     EISSN: 15221601     Source Type: Journal    
DOI: 10.1152/japplphysiol.00901.2006     Document Type: Article

References (38)

1. Aksnes AK, Hjeltnes N, Wahlstrom EO, Katz A, Zierath JR, and Wallberg-Henriksson H. Intact glucose transport in morphologically altered denervated skeletal muscle from quadriplegic patients. Am J Physiol Endocrinol Metab 271: E593-E600, 1996.
2. Aldridge A, Aranda JV, Neims AH. Caffeine metabolism in the newborn. Clin Pharmacol Ther 25: 447-453, 1979.
3. Arnold JM, Feng QP, Delaney GA, Teasell RW. Autonomic dysreflexia in tetraplegic patients: evidence for alpha-adrenoceptor hyperresponsiveness. Clin Auton Res 5: 267-270, 1995.
4. Battram DS, Graham TE, Richter EA, Dela F. The effect of caffeine on glucose kinetics in humans - influence of adrenaline. J Physiol 569: 347-355, 2005.
5. Bauman WA, Adkins RH, Spungen AM, Waters RL. The effect of residual neurological deficit on oral glucose tolerance in persons with chronic spinal cord injury. Spinal Cord 37: 765-771, 1999.
6. Biaggioni I, Paul S, Puckett A, Arzubiaga C. Caffeine and theophylline as adenosine receptor antagonists in humans. J Pharmacol Exp Ther 258: 588-593, 1991.
7. Bluher M, Fasshauer M, Tonjes A, Kratzsch J, Schon MR, Paschke R. Association of interleukin-6, C-reactive protein, interleukin-10 and adiponectin plasma concentrations with measures of obesity, insulin sensitivity and glucose metabolism. Exp Clin Endocrinol Diabetes 113: 534-537, 2005.
8. Ciaraldi TP. The role of adenosine in insulin action coupling in rat adipocytes. Mol Cell Endocrinol 60: 31-41, 1988.
9. Crist GH, Xu B, Lanoue KF, Lang CH. Tissue-specific effects of in vivo adenosine receptor blockade on glucose uptake in Zucker rats. FASEB J 12: 1301-1308, 1998.
10. Espinal J, Challiss RA, Newsholme EA. Effect of adenosine deaminase and an adenosine analogue on insulin sensitivity in soleus muscle of the rat. FEBS Lett 158: 103-106, 1983.
11. Fritsche A, Madaus A, Stefan N, Tschritter O, Maerker E, Teigeler A, Haring H, Stumvoll M. Relationships among age, proinsulin conversion, and beta-cell function in nondiabetic humans. Diabetes 51, Suppl 1: S234-S239, 2002.
12. Graham TE, Helge JW, MacLean DA, Kiens B, Richter EA. Caffeine ingestion does not alter carbohydrate or fat metabolism in human skeletal muscle during exercise. J Physiol 529: 837-847, 2000.
13. Graham TE, Sathasivam P, Rowland M, Marko N, Greer F, Battram D. Caffeine ingestion elevates plasma insulin response in humans during an oral glucose tolerance test. Can J Physiol Pharmacol 79: 559-565, 2001.
14. Green A. Catecholamines inhibit insulin-stimulated glucose transport in adipocytes, in the presence of adenosine deaminase. FEBS Lett 152: 261-264, 1983.
15. Green A. Adenosine receptor down-regulation and insulin resistance following prolonged incubation of adipocytes with an A1 adenosine receptor agonist. J Biol Chem 262: 15702-15707, 1987.
16. Greer F, Hudson R, Ross R, Graham T. Caffeine ingestion decreases glucose disposal during a hyperinsulinemic-euglycemic clamp in sedentary humans. Diabetes 50: 2349-2354, 2001.
17. Han DH, Hansen PA, Nolte LA, Holloszy JO. Removal of adenosine decreases the responsiveness of muscle glucose transport to insulin and contractions. Diabetes 47: 1671-1675, 1998.
18. Heseltine L, Webster JM, Taylor R. Adenosine effects upon insulin action on lipolysis and glucose transport in human adipocytes. Mol Cell Biochem 144: 147-151, 1995.
19. Jiao Y, Shashkin P, Hjeltnes N, Wallberg-Henriksson H, Katz A. Altered glycogen synthase and phosphorylase activities in skeletal muscle of tetraplegic patients. Exp Physiol 86: 205-209, 2001.
20. Johnston KL, Clifford MN, Morgan LM. Coffee acutely modifies gastrointestinal hormone secretion and glucose tolerance in humans: glycemic effects of chlorogenic acid and caffeine. Am J Clin Nutr 78: 728-733, 2003.
21. Kaartinen JM, Hreniuk SP, Martin LF, Ranta S, Lanoue KF, Ohisalo JJ. Attenuated adenosine-sensitivity and decreased adenosine-receptor number in adipocyte plasma membranes in human obesity. Biochem J 279: 17-22, 1991.
22. Keijzers GB, De Galan BE, Tack CJ, Smits P. Caffeine can decrease insulin sensitivity in humans. Diabetes Care 25: 364-369, 2002.
23. Laurent D, Petersen KF, Russell RR, Cline GW, Shulman GI. Effect of epinephrine on muscle glycogenolysis and insulin-stimulated muscle glycogen synthesis in humans. Am J Physiol Endocrinol Metab 274: E130-E138, 1998.
24. Lee AD, Hansen PA, Schluter J, Gulve EA, Gao J, Holloszy JO. Effects of epinephrine on insulin-stimulated glucose uptake and GLUT-4 phosphorylation in muscle. Am J Physiol Cell Physiol 273: C1082-C1087, 1997.
25. Lee S, Hudson R, Kilpatrick K, Graham TE, Ross R. Caffeine ingestion is associated with reductions in glucose uptake independent of obesity and type 2 diabetes before and after exercise training. Diabetes Care 28: 566-572, 2005.
26. Leighton B, Lozeman FJ, Vlachonikolis IG, Challiss RA, Pitcher JA, Newsholme EA. Effects of adenosine deaminase on the sensitivity of glucose transport, glycolysis and glycogen synthesis to insulin in muscles of the rat. Int J Biochem 20: 23-27, 1988.
27. Lowry OH, Passonneau JV. In: Enzymatic Analysis: A Practical Guide. Totowa, NJ: Humana, 1993, p. 172.
28. Matsuda M, DeFronzo RA. Insulin sensitivity indices obtained from oral glucose tolerance testing: comparison with the euglycemic insulin clamp. Diabetes Care 22: 1462-1470, 1999.
29. Petrie HJ, Chown SE, Belfie LM, Duncan AM, McLaren DH, Conquer JA, Graham TE. Caffeine ingestion increases the insulin response to an oral-glucose-tolerance test in obese men before and after weight loss. Am J Clin Nutr 80: 22-28, 2004.
30. Robinson LE, Savani S, Battram DS, McLaren DH, Sathasivam P, Graham TE. Caffeine ingestion before an oral glucose tolerance test impairs blood glucose management in men with type 2 diabetes. J Nutr 134: 2528-2533, 2004.
31. Smits P, Boekema P, De Abreu R, Thien T, van't Laar A. Evidence for an antagonism between caffeine and adenosine in the human cardiovascular system. J Cardiovasc Pharmacol 10: 136-143, 1987.
32. Smits P, Hoffmann H, Thien T, Houben H, and van't Laar A. Hemodynamic and humoral effects of coffee after beta 1-selective and nonselective beta-blockade. Clin Pharmacol Ther 34: 153-158, 1983.
33. Smits P, Lenders JW, Thien T. Caffeine and theophylline attenuate adenosine-induced vasodilation in humans. Clin Pharmacol Ther 48: 410-418, 1990.
34. Thong FS, Derave W, Kiens B, Graham TE, Urso B, Wojtaszewski JF, Hansen BF, Richter EA. Caffeine-induced impairment of insulin action but not insulin signaling in human skeletal muscle is reduced by exercise. Diabetes 51: 583-590, 2002.
35. Thong FS, Graham TE. Caffeine-induced impairment of glucose tolerance is abolished by β-adrenergic receptor blockade in humans. J Appl Physiol 92: 2347-2352, 2002.
36. Van Soeren M, Mohr T, Kjaer M, Graham TE. Acute effects of caffeine ingestion at rest in humans with impaired epinephrine responses. J Appl Physiol 80: 999-1005, 1996.
37. Vannucci SJ, Nishimura H, Satoh S, Cushman SW, Holman GD, Simpson IA. Cell surface accessibility of GLUT4 glucose transporters in insulin-stimulated rat adipose cells. Modulation by isoprenaline and adenosine Biochem J 288: 325-330, 1992.
38. Vergauwen L, Hespel P, Richter EA. Adenosine receptors mediate synergistic stimulation of glucose uptake and transport by insulin and by contractions in rat skeletal muscle. J Clin Invest 93: 974-981, 1994.