Neuronal CCK and thermoregulation: Two receptors with different functions

American Journal of Physiology - Regulatory Integrative and Comparative Physiology

Volumn 292, Issue 1, 2007, Pages

  Szelényi, Zoltán ^a  

^a UNIVERSITY OF PÉCS   (Hungary)

Author keywords

[No Author keywords available]

Indexed keywords

1 (2,3 DIHYDRO 1 METHYL 2 OXO 5 PHENYL 1H 1,4 BENZODIAZEPIN 3 YL) 3 (3 METHYLPHENYL)UREA; CHOLECYSTOKININ A RECEPTOR; CHOLECYSTOKININ B RECEPTOR; CHOLECYSTOKININ OCTAPEPTIDE; DEVAZEPIDE; INTERLEUKIN 6; LIPOPOLYSACCHARIDE;

BIOLOGICAL ACTIVITY; BODY TEMPERATURE; CORE TEMPERATURE; EDITORIAL; ENERGY METABOLISM; FOOD INTAKE; HUMAN; HYPERTHERMIA; HYPOTHERMIA; ILLNESS BEHAVIOR; NERVE CELL; NONHUMAN; PRIORITY JOURNAL; PROTEIN FUNCTION; SATIETY; THERMOGENESIS; THERMOREGULATION;

ANIMALS; BODY TEMPERATURE; BODY TEMPERATURE REGULATION; CHEMOKINES; CHOLECYSTOKININ; ENERGY METABOLISM; FEVER; HUMANS; LIPOPOLYSACCHARIDES; MICE; MICE, KNOCKOUT; NEURONS; RECEPTOR, CHOLECYSTOKININ B; RECEPTORS, CHOLECYSTOKININ;

EID: 33846131957     PISSN: 03636119     EISSN: 15221490     Source Type: Journal    
DOI: 10.1152/ajpregu.00620.2006     Document Type: Editorial

References (38)

1. Andre J, Yeau B, Pohl M, Cesselin F, Benoliel JJ, Becker C. Involvement of cholecystokininergic systems in anxiety-induced hyperalgesia in male rats: behavioral and biochemical studies. J Neurosci 25: 7896-7904, 2005.
2. Bi S, Scott KA, Kopin AS, Moran TH. Differential roles for cholecystokinin receptors in energy balance in rats and mice. Endocrinology 145: 3873-3880, 2004.
3. Castandon N, Bluthé RM, Danzer R. Chronic treatment with the atypic antidepressant tianeptin attenuates sickness behavior induced by peripheral but not central lipopolysaccharide and interleukin-1beta in the rat. Psychopharmacology (Berl) 154: 50-60, 2001.
4. Charlton BG. The malaise theory of depression: Major depressive disorder is sickness behavior and antidepressants are analgesic. Med Hypotheses 54: 126-130, 2000.
5. Chen Q, Nakajima A, Meacham C, Tang YP. Elevated cholecystokininergic tone constitutes an important molecular/neuronal mechanism for the expression of anxiety in the mouse. Proc Natl Acad Sci USA 103: 3881-3886, 2006.
6. Dantzer R. Cytokines, sickness behavior, and depression. Neurol Clin 24: 441-460, 2006.
7. Day NC, Hall MD, Clark CR, Hughes J. High concentration of cholecystokinin receptor binding sites in the ventromedial hypothalamic nucleus. Neuropeptides 8: 1-18, 1986.
8. DeMesquita S, Haney WH. Effect of chronic intracerebroventricular infusion of cholecystokinin on respiration and sleep. Brain Res 378: 127-132, 1986.
9. Ghosh S, Geller EB, Adler MW. Interaction of cholecystokinin and somatostatin with selective μ-opioid agonist and μ- and δ-antagonists in thermoregulation. Brain Res 745: 152-157, 1997.
10. Gibbs J, Young R, Smith GP. Cholecystokin decreases food intake in rats. J Comp Physiol 84: 488-493, 1973.
11. Hart BL. Biological basis of the behavior of sick animals. Neurosci Biobehav Rev 12: 123-137, 1988.
12. Ivanov AI, Kulchitsky VA, Romanovsky AA. Role for the cholecystokinin-A receptor in fever: a study of a mutant rat strain and a pharmacological analysis. J Physiol 547: 941-949, 2003.
13. Kandashamy SB, Williams BA. Cholecystokinin-octapeptide-induced hyperthermia in guinea-pigs. Experientia 39: 1282-1284, 1983.
14. Kapas L, Obal, F Jr, Alföldi P, Rubicsek Gy Penke B, Obal. F. Effects of nocturnal intraperitoneal administration of cholecystokinin in rats: simultaneous increase in sleep: Increase in EEG slow-wave activity, reduction of motor activity, suppression of eating, and decrease in brain temperature. Brain Res 438: 155-164, 1988.
15. Katsuura G, Hirota R, Itoh S. Cholecystokinin-induced hypothermia in the rat. Experientia 37: 60, 1981.
16. Kurosawa M, Iijima S, Funakoshi A, Kawanami T, Miyasaka K, Bucinskaite V, Lundeberg T. Cholecystokin-8 (CCK-8) has no effect on heart rate in rats lacking CCK-A receptors. Peptides 22: 1279-1284, 2001.
17. Larsson LI, Rehfeld JF. Localization and molecular heterogeneity of cholecystokinin in the central and peripheral nervous sytem. Brain Res 165: 210-218, 1979.
18. Liu HJ, Lin MT. Cholecystokinin-induced hypothermia: possible involvement of serotoninergic mechanisms in the rat hypothalamus. Pharmacology 31: 108-114, 1985.
19. Miyasaka K, Kanai S, Ohta M, Kawanami T, Kono A, Funakoshi A. Lack of satiety effect of cholecystokinin (CCK) in a new rat model not expressing the CCK-A receptor gene. Neurosci Lett 180: 143-146, 1994.
20. Moran TH, Smith GP, Hostetler AM, McHugh PR. Transport of cholecystokinin (CCK) binding sites in subdiaphragmatic vagal branches. Brain Res 415: 149-152, 1987.
21. Morimoto A, Ono T, Watanabe T, Murakami N. Activation of brain regions of rats during fever. Brain Res 381: 100-105, 1986.
22. Morley JE, Levine AS, Lindblad S. Intracerebroventricular cholecystokinin-octapeptide produces hypothermia in rats. Eur J Pharmacol 74: 249-251, 1981.
23. Nomoto S, Ohta M, Kanai S, Yoshida Y, Takiguchi S, Funakoshi A, Miyasaka K. Absence of the cholecystokinin-A receptor deteriorates homeostasis of body temperature in response to changes in ambient temperature. Am J Physiol Regul Integr Comp Physiol 287: R556-R561, 2004.
24. Reidelberger RD, Hernandez J, Fritzsch B, Hulce M. Abdominal vagal mediation of the satiety effects of CCK in rats. Am J Physiol Regul Integr Comp Physiol 286: R991-R993, 2004.
25. Rudaya AY, Steiner AA, Robbins JR, Dragic AS, Romanovsky AA. Themoregulatory responses to lipopolysaccharide in the mouse: dependence on the dose and ambient temperature. Am J Physiol Regul Integr Comp Physiol 289: R1244-R1252, 2005.
26. Saita M, Verberne AJ. Roles for CCK1 and 5-HT3 receptors in the effects of CCK on presympathetic vasomotor neuronal discharge in the rat. Br J Pharmacol 139: 415-423, 2003.
27. Sanches-Fernandez C, Gonzalez C, Mercer LD, Beart PM, Ruiz-Gayo M, Fernandez-Alfonso MS. Cholecystokinin induces cerebral vasodilatation via presynaptic CCK2 receptos: new implications for the pathophysiology of panic. J Cereb Blood Flow Metab 23: 364-370, 2003.
28. Sartor DM, Verberne AJ. The sympathoinhibitory effects of systemic cholecystokinin are dependent on neurons in the caudal ventrolateral medulla in the rat. Am J Physiol Regul Integr Comp Physiol 291: R1390-R1398, 2006.
29. Sei M, Sei H, Shima K. Spontaneous activity, sleep, and body temperature in rats lacking the CCK-A receptor. Physiol Behav 68: 25-29, 1999.
30. Swiergiel AH, Dunn AJ. Feeding, exploratory, anxiety- and depression-related behaviors are not altered in interleukin-6-deficient male mice. Behav Brain Res 171: 94-108, 2006.
31. Sugimoto N, Simons CT, Romanovsky AA. Vagotomy does not affect responsiveness to intrabrain prostaglandin E2 and cholecystokinin octapeptide. Brain Res 844: 157-163, 1999.
32. Székely M, Szelényi Z, Balaskó M. Cholecystokinin participates in the mediation of fever. Pflügers Arch 428: 671-673, 1994.
33. Szelényi Z, Barthó L, Székely M, Romanovsky AA. Cholecystokinin octapeptide (CCK-8) injected into a cerebral ventricle induces a fever-like thermoregulatory response mediated by type B CCK-receptors in the rat. Brain Res 638: 69-77, 1994.
34. Szelényi Z, Hummel Z, Székely M, Pétervári E. CCK-8 and PGE1: central effects on circadian body temperature and activity in rats. Physiol Behav 81: 615-621, 2004.
35. Wang H, Wong PT, Spiess J, Zhu YZ. Cholecystokinin-2 (CCK-2) receptor-mediated anxiety-like behaviors in rats. Neurosci Biobehav Rev 29: 1361-1373, 2005.
36. Weiland TJ, Voudouris NJ, Kent S. The role of CCK2 receptors in energy homeostasis: Insights from the CCK2 receptor-deficient mouse. Physiol Behav 82: 471-476, 2004.
37. 2 receptor nullification attenuates lipopolysaccaride-induced sickness behavior. Am J Physiol Regul Integr Comp Physiol 292: R112-R123, 2007.
38. Zetler G. Cholecystokinin octapeptide, caerulein and caerulein analogues: effects on thermoregulation in the mouse. Neuropharmacology 21: 795-801, 1982.