Mutagenicity test for functional food containing superfine dispersed Lentinan (β-1,3-glucan) - Reverse mutation test, chromosomal aberration test and mouse micronucleus test

Biotherapy

Volumn 20, Issue 6, 2006, Pages 557-567

  Odagiri, Yasuteru ^a   Yokoi, Orie ^a   Sui, Hajime ^b   Yamakage, Kohji ^b   Suga, Tetsuya ^a   Masuyama, Takeshi ^a  

^a AJINOMOTO CO INC   (Japan)

^b HATANO RESEARCH INSTITUTE   (Japan)

Author keywords

1,3 glucan; Chromosomal aberration test; Lentinan; Mouse micronucleus test; Reverse mutation test

Indexed keywords

BETA 1,3 GLUCAN; LENTINAN;

ANIMAL CELL; ANIMAL EXPERIMENT; ARTICLE; CHROMOSOME ABERRATION; CONTROLLED STUDY; DRUG RESEARCH; FUNCTIONAL FOOD; IN VITRO STUDY; MICRONUCLEUS TEST; MOUSE; MUTAGEN TESTING; NONHUMAN; REVERTANT;

EID: 33846129387     PISSN: 09142223     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (20)

1. Chihara, G., Maeda, Y. Y., Hamuro, J., et al.: Inhibition of mouse Sarcoma 180 by the polysaccharide from Lentinus edodes (Berk) Sing. Nature 222: 678-679, 1969.
2. Hamuro, J., Wagner, H. and Röllinghoff, M.: β (1→3)glucan as a probe for T-cell specific immune adjuvant: enhanced in vitro generation of cytotoxic T-lymphocytes. Cell Immunol. 38: 328-335, 1978.
3. Chihara, G., Maeda, Y. Y., Suga, T., et al.: Lentinan as a host defence potentiator (HDP). Int. J. Immunother. V: 145-154, 1989.
4. Japanese source
5. Japanese source
6. Fragrance J. 32: 87-96, 2003.
7. Biotherapy 17: 267-273, 2003.
8. Biotherapy 19: 273-278, 2005.
9. Japanese source
10. Biotherapy 19: 283-287, 2005.
11. Japanese source
12. Japanese source
13. Japanese source
14. Japanese source
15. Hayashi, M., Tice, R. R. and MacGregor, J. T.: In vivo rodent erythrocyte micronucleus assay. Mutat. Res. 312: 293-304, 1994.
16. Margolin, B. H., Resnick, M. A., Rimpo, J. Y., et al.: Statistical analyses for in vitro cytogenetic assays using Chinese hamster ovary cells. Environ. Mutagen. 8: 183-204, 1986.
17. Margolin, B. H. and Risko, K. J.: In Evaluation of Short-Term Tests for Carcinogens (edited by Ashby, J., et al.), vol.1, Cambridge University Press, 1988, pp. 29-42.
18. Snedecor, G. W. and Cochran, W. G.: Statistical Methods, 7th Ed, Iowa State University Press, Iowa, 1980.
19. Dunnett, C. W.: A multiple comparison procedure for comparing several treatments with a control. J. Am. Statist. Assoc. 50: 1096-1121, 1955.
20. Japanese source