The involvement of phosphatidylinositol 3-kinase /Akt signaling in high glucose-induced downregulation of GLUT-1 expression in ARPE cells

Life Sciences

Volumn 80, Issue 7, 2007, Pages 626-632

  Kim, Dong Il ^a   Lim, Sul Ki ^a   Park, Min Jung ^a   Han, Ho Jae ^a   Kim, Gye Yeop ^b   Park, Soo Hyun ^a  

^a Chonnam National University   (South Korea)

^b Dongshin University   (South Korea)

Author keywords

Diabetic retinopathy; PI 3 kinase Akt; Protein kinase C; Retinal pigment epithelial cells

Indexed keywords

1 (5 ISOQUINOLINESULFONYL) 2 METHYLPIPERAZINE; 2 MORPHOLINO 8 PHENYLCHROMONE; ANTIOXIDANT; ASCORBIC ACID; BISINDOLYLMALEIMIDE; DEOXYGLUCOSE; GLUCOSE; GLUCOSE TRANSPORTER 1; LIPID PEROXIDE; PHOSPHATIDYLINOSITOL 3 KINASE; PROTEIN KINASE B; STAUROSPORINE;

ANALYTIC METHOD; ARTICLE; CONTROLLED STUDY; DOSE RESPONSE; DOWN REGULATION; ENZYME ACTIVATION; ENZYME PHOSPHORYLATION; GLUCOSE TRANSPORT; HUMAN; HUMAN CELL; LIPID PEROXIDATION; PIGMENT EPITHELIUM; PROTEIN EXPRESSION; SIGNAL TRANSDUCTION;

1-PHOSPHATIDYLINOSITOL 3-KINASE; ANDROSTADIENES; ANTIBODIES, BLOCKING; ANTIOXIDANTS; CELL LINE; CHROMONES; DEOXYGLUCOSE; DOSE-RESPONSE RELATIONSHIP, DRUG; DOWN-REGULATION; ENZYME INHIBITORS; GENE EXPRESSION; GLUCOSE; GLUCOSE TRANSPORTER TYPE 1; HUMANS; LIPID PEROXIDATION; MORPHOLINES; PIGMENT EPITHELIUM OF EYE; PROTEIN KINASE C; PROTO-ONCOGENE PROTEINS C-AKT; RNA, MESSENGER; SIGNAL TRANSDUCTION;

EID: 33846120108     PISSN: 00243205     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.lfs.2006.10.026     Document Type: Article

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