Statin attenuates high glucose-induced and angiotensin II-induced MAP kinase activity through inhibition of NAD(P)H oxidase activity in cultured mesangial cells.

Medicinal chemistry

Volumn 1, Issue 5, 2005, Pages 461-466

  Yu, H Y ^a   Inoguchi, T ^a   Nakayama, M ^a   Tsubouchi, H ^a   Sato, N ^a   Sonoda, N ^a   Sasaki, S ^a   Kobayashi, K ^a   Nawata, H ^a  

^a KYUSHU UNIVERSITY   (Japan)

Author keywords

[No Author keywords available]

Indexed keywords

ANGIOTENSIN II; CALPHOSTIN COMPLEX; CATION; DIPHENYLIODONIUM SALT; GLUCOSE; HYDROXYMETHYLGLUTARYL COENZYME A REDUCTASE INHIBITOR; MITOGEN ACTIVATED PROTEIN KINASE; NAPHTHALENE DERIVATIVE; PITAVASTATIN; QUINOLINE DERIVATIVE; REDUCED NICOTINAMIDE ADENINE DINUCLEOTIDE PHOSPHATE OXIDASE; UNCLASSIFIED DRUG;

ARTICLE; CELL CULTURE; DOSE RESPONSE; DRUG ANTAGONISM; DRUG EFFECT; ELECTRON SPIN RESONANCE; ENZYMOLOGY; HUMAN; MESANGIUM CELL; METABOLISM; METHODOLOGY; OXIDATIVE STRESS; PHYSIOLOGY; SENSITIVITY AND SPECIFICITY; STRUCTURE ACTIVITY RELATION;

ANGIOTENSIN II; CELLS, CULTURED; DOSE-RESPONSE RELATIONSHIP, DRUG; ELECTRON SPIN RESONANCE SPECTROSCOPY; GLUCOSE; HUMANS; HYDROXYMETHYLGLUTARYL-COA REDUCTASE INHIBITORS; MESANGIAL CELLS; MITOGEN-ACTIVATED PROTEIN KINASES; NADPH OXIDASE; NAPHTHALENES; ONIUM COMPOUNDS; OXIDATIVE STRESS; QUINOLINES; RESEARCH SUPPORT, NON-U.S. GOV'T; SENSITIVITY AND SPECIFICITY; STRUCTURE-ACTIVITY RELATIONSHIP;

EID: 33846118471     PISSN: 15734064     EISSN: None     Source Type: Journal    
DOI: 10.2174/1573406054864052     Document Type: Article

References (0)