Pharmacokinetics of Mycophenolic Acid and Its Glucuronide After a Single and Multiple Oral Dose of Mycophenolate Mofetil in Chinese Renal Transplantation Recipients

Transplantation Proceedings

Volumn 38, Issue 7, 2006, Pages 2044-2047

  Liang, M Z ^a   Lu, Y P ^a   Nan, F ^a   Li, Y P ^a  

^a SICHUAN UNIVERSITY   (China)

Author keywords

[No Author keywords available]

Indexed keywords

CYCLOSPORIN; MYCOPHENOLIC ACID; MYCOPHENOLIC ACID BETA D GLUCURONIDE; UNCLASSIFIED DRUG;

ADULT; ARTICLE; CHINESE; CLINICAL ARTICLE; COMPARTMENT MODEL; DISTRIBUTION VOLUME; DRUG BLOOD LEVEL; DRUG HALF LIFE; DRUG MONITORING; ENTEROHEPATIC CIRCULATION; FEMALE; HUMAN; KIDNEY TRANSPLANTATION; MALE; MULTIPLE DRUG DOSE; PRIORITY JOURNAL; RECIPIENT; REVERSED PHASE HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; SINGLE DRUG DOSE;

ADULT; AREA UNDER CURVE; CHINA; CHROMATOGRAPHY, HIGH PRESSURE LIQUID; DRUG ADMINISTRATION SCHEDULE; FEMALE; GLUCURONIDES; HUMANS; IMMUNOSUPPRESSIVE AGENTS; KIDNEY TRANSPLANTATION; MALE; MYCOPHENOLIC ACID;

EID: 33846113110     PISSN: 00411345     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.transproceed.2006.06.027     Document Type: Article

References (4)

1. Nan F., Yu Q., Liang M.-z., et al. RP-HPLC determination of mycophenolic acid in human plasma of renal transplantation patients. Chin J Pharm Anal 24 (2004) 275 (in Chinese)
2. Shipkova M., Niedmann P.D., Armstrong V.W., et al. Simultaneous determination of mycophenolic acid and its glucuronide in human plasma using a simple high-performance liquid chromatography procedure. Clin Chem 44 (1998) 1481
3. Johnson A.G., Rigby R.J., Taylor P.J., et al. The kinetics of mycophenolic acid and its glucuronide metabolite in adult kidney transplant recipients. Clin Pharmacol Ther 66 (1999) 492
4. Johnson H.J., Swan S.K., Heim-Duthoy K.L., et al. The pharmacokinetics of a single oral dose of mycophenolate mofetil in patients with varying degrees of renal function. Clin Pharmacol Ther 63 (1998) 512