Immunohistochemical detection of protein gene product 9.5 (PGP 9.5) in canine epitheliotropic T-cell lymphoma (mycosis fungoides)

Veterinary Pathology

Volumn 44, Issue 1, 2007, Pages 74-79

  Ramos Vara, José A ^a   Miller, M A ^a  

^a PURDUE UNIVERSITY   (United States)

Author keywords

CD3; CD79a; Dogs; Immunohistochemistry; Lymphoma; Mycosis fungoides; Pathology; PGP 9.5

Indexed keywords

TUMOR MARKER; UBIQUITIN THIOLESTERASE;

ANIMAL; ANIMAL DISEASE; ARTICLE; BIOPSY; DOG; DOG DISEASE; ENZYMOLOGY; FEMALE; IMMUNOHISTOCHEMISTRY; MALE; METABOLISM; MYCOSIS FUNGOIDES; PATHOLOGY; SKIN TUMOR;

ANIMALS; BIOPSY; DOG DISEASES; DOGS; FEMALE; IMMUNOHISTOCHEMISTRY; MALE; MYCOSIS FUNGOIDES; SKIN NEOPLASMS; TUMOR MARKERS, BIOLOGICAL; UBIQUITIN THIOLESTERASE;

CANIS FAMILIARIS;

EID: 33846080068     PISSN: 03009858     EISSN: 15442217     Source Type: Journal    
DOI: 10.1354/vp.44-1-74     Document Type: Article

References (34)

1. Ackerman L: Oral T cell-like lymphoma in a dog. J Amer Anim Hosp Assoc 20:955-958, 1984
2. Aumuller G, Renneberg H, Leonhardt M, Lilja H, Abrahamson PA: Localization of protein gene product 9.5 immunoreactivity in derivatives of the human Wolfian duct and in prostate cancer. Prostate 38:261-267, 1999
3. Brelińska R, Ostalska D, Zabel M: Subtypes of thymic epithelial cells defined by neuroendocrine markers. Histochem Cell Biol 114:239-244, 2000
4. Campbell LK, Thomas JR, Lamps LW, Smoller BR, Folpe AL: Protein gene product 9.5 is not a specific marker of neural and nerve sheath tumors: An immunohistochemical study of 95 mesenchymal neoplasms. Mod Pathol 16:963-969, 2003
5. D'Andrea V, Malinovsky L, Berni A, Biancari F, Biassoni L, Di Matteo FM, Corbellini L, Falvo L, Santoni F, Spyrou M, De Antoni E: The immunolocalization of PGP 9.5 in normal human kidney and renal cell carcinoma. G Chir 18:521-524, 1997
6. De la Fuente EG, Rodriguez-Peralto JL, Ortiz PL, Barrientos N, Vanaclocha F, Iglesias L: Oral involvement in mycosis fungoides: report of two cases and a literature review. Acta Dermatol Venereol 80:299-301, 2000
7. Diomedi-Camascci F, Ravà L, Lerut E, Callea F, Van Damme B: Protein gene product 9.5 and ubiquitin are expressed in metabolically active epithelial cells of normal and pathologic human kidney. Nephrol Dial Transplant 20:2714-2719, 2005
8. Fletcher CDM: Mycosis fungoides. In: Diagnostic Histopathology of Tumors, ed. Fletcher CDM, 2nd ed., pp. 1440-1442. Churchill Livingstone, London, 2002
9. Gross TL, Ihrke PJ, Walder EJ, Affolter VK: Epitheliotropic lymphoma. In: Skin Diseases of the Dog and Cat, ed. Gross TL, Ihrke PJ, Walder EJ, and Affolter VK, 2nd ed., pp. 876-883. Blackwell, Oxford, 2005
10. Hamzeh H, Gaudillère A, Sabido O, Tchou I, Lambert C, Schmitt D, Genin C, Misery L: Expression of PGP9.5 on Langerhan's cells and their precursors. Acta Derm Venereol 80:14-16, 2000
11. Harris MD, Moore IE, Steart PV, Weller RO: Protein gene product (PGP) 9.5 as a reliable marker in primitive neuroectodermal tumours. An immunohistochemical study of 21 childhood cases. Histopathology 16:271-277, 1990
12. Hershko A, Ciechanover A, Varshavsky A: The ubiquitin system. Nat Med 6:1073-1081, 2000
13. Hibi K, Westra WH, Borges M, Goodman S, Sidransky D, Jen J: PGP9.5 as a candidate tumor marker for non-small-cell lung cancer. Am J Pathol 155:711-715, 1999
14. Hilliges M, Hellman M, Ahlstrom U, Johansson O: Immunohistochemical studies of neurochemical markers in normal human buccal mucosa. Histochemistry 101:235-244, 1994
15. Jackson P, Thompson RJ: The demonstration of new human brain-specific proteins by high-resolution two-dimensional polyacrylamide gel electrophoresis. J Neurol Sci 49:429-438, 1981
16. Langlois NEI, King G, Herriot R, Thompson WD: Non-enzymatic retrieval of antigen permits staining of follicle centre cells by the rabbit polyclonal antibody to protein gene product 9.5. J Pathol 173:249-253, 1994
17. Langlois NEI, King G, Herriot R, Thompson WD: An evaluation of the staining of lymphomas and normal tissues by the rabbit polyclonal antibody to protein gene product 9.5 following non-enzymatic retrieval of antigen. J Pathol 175:433-439, 1995
18. Martin R, Fraile B, Peinado F, Arenas MI, Elices M, Alonso L, Paniagua R, Martin JJ, Santamaria L: Immunohistochemical localization of protein gene product 9.5, ubiquitin, and neuropeptide Y immunoreactivities in epithelial and neuroendocrine cells from normal and hyperplastic human prostate. J Histochem Cytochem 48:1121-1130, 2000
19. Olerud JE, Chiu DS, Usui ML, Gibran NS, Ansel JC: Protein gene product 9.5 is expressed by fibroblasts in human cutaneous wounds. J Invest Dermatol 111:565-572, 1998
20. Pickart CM: Back to the future with ubiquitin. Cell 116:181-190, 2004
21. Ramos-Vara JA, Beissenherz ME: Optimization of immunohistochemical methods using two different antigen retrieval methods on formalin-fixed, paraffin-embedded tissues: experience with 63 markers. J Vet Diag Invest 12:307-311, 2000
22. Rode J, Dhillon AP, Doran JF, Jackson P, Thompson RJ: PGP 9.5, a new marker for human neuroendocrine tumours. Histopathology 9:147-158, 1985
23. Rosai J: Mycosis fungoides and related peripheral T-cell lymphomas. In: Rosai and Ackerman's Surgical Pathology, ed. Rosai J, 9th ed., pp. 197-199. Mosby, Edinburgh, UK, 2004
24. Santamaria L, Martin R, Paniagua R, Fraile B, Nistal M, Terenghi G, Polak JM: Protein gene product 9.5 and ubiquitin immunoreactivities in rat epididymis epithelium. Histochemistry 100:131-138, 1993
25. Sasaki H, Yukiue H, Moriyama S, Kobayasho Y, Nakashima Y, Kaji M, Fukai I, Kiriyama Y, Fujii Y: Expression of the protein gene product 9.5, PGP9.5, is correlated with T-status in non-small cell lung cancer. Jpn J Clin Oncol 31:532-535, 2001
26. Schumacher U, Mitchell BS, Kaiserling E: The neuronal marker protein gene product 9.5 (PGP 9.5) is phenotypically expressed in human breast epithelium, in milk, and in benign and malignant breast tumors. DNA Cell Biol 13:839-843, 1994
27. Singh N, Wright DH: The value of immunohistochemistry on paraffin wax embedded tissue sections in the differentiation of small lymphocyte and mantle cell lymphomas. J Clin Pathol 50:16-21, 1997
28. Spataro V, Norbury C, Harris AL: The ubiquitin-proteasome pathway in cancer. Br J Cancer 77:448-455, 1998
29. Tezel E, Hibi K, Nagasaka T, Nakao A: PGP9.5 as a prognostic factor in pancreatic cancer. Clin Cancer Res 6:4764-4767, 2000
30. Thompson RJ, Doran JF, Jackson P, Dhillon AP, Rode J: PGP 9.5- a new marker for vertebrate neurons and neuroendocrine cells. Brain Res 278:224-228, 1983
31. Wain EM, Setterfield J, Judge MR, Harper JI, Pemberton MN, Russell-Jones R: Mycosis fungoides involving the oral mucosa in a child. Clin Exp Dermatol 28:499-501, 2003
32. Wang Y, Einhorn P, Triche TJ, Seeger RC, Reynolds CP: Expression of protein gene product 9.5 and tyrosine hydroxylase in childhood small round cell tumors. Clin Cancer Res 6:551-558, 2000
33. Wilkinson KD, Lee K, Deshpande S, Duerksen-Hughes P, Boss JM, Pohl J: The neuron-specific protein PGP 9.5 is a ubiquitin carboxyl-terminal hydrolase. Science 246:670-673, 1989
34. Wilson PO, Barber PC, Hamid QA, Power BF, Dhillon AP, Rode J, Day IN, Thompson RJ, Polak JM: The immunolocalization of protein gene product 9.5 using rabbit polyclonal and mouse monoclonal antibodies. Br J Exp Pathol 69:91-104, 1988