PEPT1 enhances the uptake of gabapentin via trans-stimulation of b 0,+ exchange

Pharmaceutical Research

Volumn 24, Issue 2, 2007, Pages 353-360

  Nguyen, Theresa V ^a   Smith, David E ^a   Fleisher, David ^a  

^a UNIVERSITY OF MICHIGAN   (United States)

Author keywords

Amino acid transporter b0,+; Gabapentin; Intestinal perfusion; Peptide transporter PEPT1; Trans stimulation

Indexed keywords

ALANINE; ARGININE; GABAPENTIN; GLUTAMATE AMMONIA LIGASE; GLUTAMINE; GLYCYLGLUTAMINE; GLYCYLSARCOSINE; LEUCINE; LYSINE; METHIONINE SULFOXIMINE; PEPTIDE TRANSPORTER 1;

ANIMAL EXPERIMENT; ARTICLE; CONTROLLED STUDY; DRUG MECHANISM; DRUG PENETRATION; DRUG UPTAKE; ILEUM; INTESTINE PERFUSION; JEJUNUM; MALE; NONHUMAN; PRIORITY JOURNAL; RAT; STATISTICAL SIGNIFICANCE;

AMINES; AMINO ACID TRANSPORT SYSTEMS; AMINO ACIDS; ANIMALS; ARGININE; BIOLOGICAL TRANSPORT, ACTIVE; CYCLOHEXANECARBOXYLIC ACIDS; DIPEPTIDES; GAMMA-AMINOBUTYRIC ACID; GLUCOSE; GLUTAMATE-AMMONIA LIGASE; HYDROGEN-ION CONCENTRATION; INTESTINES; LYSINE; MALE; RATS; RATS, SPRAGUE-DAWLEY; SODIUM; SYMPORTERS; WATER;

EID: 33846069685     PISSN: 07248741     EISSN: 1573904X     Source Type: Journal    
DOI: 10.1007/s11095-006-9155-6     Document Type: Article

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