메뉴 건너뛰기




Volumn 21, Issue 1, 2007, Pages 73-82

Use of the sustained pain-free plus no adverse events endpoint in clinical trials of triptans in acute migraine

Author keywords

[No Author keywords available]

Indexed keywords

ALMOTRIPTAN; ELETRIPTAN; FROVATRIPTAN; NARATRIPTAN; PLACEBO; RIZATRIPTAN; SUMATRIPTAN; ZOLMITRIPTAN;

EID: 33846042038     PISSN: 11727047     EISSN: None     Source Type: Journal    
DOI: 10.2165/00023210-200721010-00006     Document Type: Article
Times cited : (31)

References (39)
  • 1
    • 0028511136 scopus 로고
    • The burden of migraine: A review of cost to society
    • Lipton RB, Stewart WF, Von Korff M. The burden of migraine: a review of cost to society. Pharmacoeconomics 1994; 6 (3): 215-21
    • (1994) Pharmacoeconomics , vol.6 , Issue.3 , pp. 215-221
    • Lipton, R.B.1    Stewart, W.F.2    Von Korff, M.3
  • 2
    • 0031767675 scopus 로고    scopus 로고
    • The burden of migraine to the individual sufferer: A review
    • Dahlöf CG, Solomon GD. The burden of migraine to the individual sufferer: a review. Eur J Neurol 1998; 5 (6): 525-33
    • (1998) Eur J Neurol , vol.5 , Issue.6 , pp. 525-533
    • Dahlöf, C.G.1    Solomon, G.D.2
  • 3
    • 0029143675 scopus 로고
    • Quality of life assessment among migraine patients treated with sumatriptan
    • Solomon GD, Skobieranda FG, Genzen JR. Quality of life assessment among migraine patients treated with sumatriptan. Headache 1995; 35: 449-54
    • (1995) Headache , vol.35 , pp. 449-454
    • Solomon, G.D.1    Skobieranda, F.G.2    Genzen, J.R.3
  • 4
    • 0005176605 scopus 로고    scopus 로고
    • Sumatriptan treatment for migraine in a health maintenance organization: Economic, humanistic, and clinical outcomes
    • Cohen JA, Beall D, Beck A, et al. Sumatriptan treatment for migraine in a health maintenance organization: economic, humanistic, and clinical outcomes. Clin Ther 1999; 21 (1): 190-204
    • (1999) Clin Ther , vol.21 , Issue.1 , pp. 190-204
    • Cohen, J.A.1    Beall, D.2    Beck, A.3
  • 5
    • 0033606092 scopus 로고    scopus 로고
    • Changes in resource use and outcomes for patients with migraine treated with sumatriptan: A managed care perspective
    • Lofland JH, Johnson NE, Batenhorst AS, et al. Changes in resource use and outcomes for patients with migraine treated with sumatriptan: a managed care perspective. Arch Intern Med 1999; 159 (8): 857-63
    • (1999) Arch Intern Med , vol.159 , Issue.8 , pp. 857-863
    • Lofland, J.H.1    Johnson, N.E.2    Batenhorst, A.S.3
  • 6
    • 0037177103 scopus 로고    scopus 로고
    • Migraine in the United States: Epidemiology and patterns of health care use
    • Lipton RB, Scher AI, Kolodner K, et al. Migraine in the United States: epidemiology and patterns of health care use. Neurology 2002; 58 (6): 885-94
    • (2002) Neurology , vol.58 , Issue.6 , pp. 885-894
    • Lipton, R.B.1    Scher, A.I.2    Kolodner, K.3
  • 7
    • 0037387243 scopus 로고    scopus 로고
    • Health care utilization in patients with migraine: Demographics and patterns of care in the ambulatory setting
    • Gibbs TS, Fleischer AB, Feldman SR, et al. Health care utilization in patients with migraine: demographics and patterns of care in the ambulatory setting. Headache 2003; 43 (4): 330-5
    • (2003) Headache , vol.43 , Issue.4 , pp. 330-335
    • Gibbs, T.S.1    Fleischer, A.B.2    Feldman, S.R.3
  • 8
    • 0034594353 scopus 로고    scopus 로고
    • The pharmacology of headache
    • Goadsby PJ. The pharmacology of headache. Prog Neurobiol 2000; 62: 509-25
    • (2000) Prog Neurobiol , vol.62 , pp. 509-525
    • Goadsby, P.J.1
  • 9
    • 0037165257 scopus 로고    scopus 로고
    • Migraine: Current understanding and treatment
    • Goadsby PJ, Lipton RB, Ferrari MD. Migraine: current understanding and treatment. N Engl J Med 2002; 346 (4): 257-70
    • (2002) N Engl J Med , vol.346 , Issue.4 , pp. 257-270
    • Goadsby, P.J.1    Lipton, R.B.2    Ferrari, M.D.3
  • 10
    • 0033404903 scopus 로고    scopus 로고
    • Acute migraine therapy: Do doctors understand what patients with migraine want from therapy?
    • Lipton RB, Stewart WF. Acute migraine therapy: do doctors understand what patients with migraine want from therapy? Headache 1999; 39 Suppl. 2: S20-6
    • (1999) Headache , vol.39 , Issue.SUPPL. 2
    • Lipton, R.B.1    Stewart, W.F.2
  • 11
    • 0037246651 scopus 로고    scopus 로고
    • Migraine medication attributes important for patient compliance: Concerns about side effects may delay treatment
    • Gallagher RM, Kunkel R. Migraine medication attributes important for patient compliance: concerns about side effects may delay treatment. Headache 2003; 43 (1): 36-44
    • (2003) Headache , vol.43 , Issue.1 , pp. 36-44
    • Gallagher, R.M.1    Kunkel, R.2
  • 12
    • 0347319254 scopus 로고    scopus 로고
    • Defeating migraine pain with triptans: A race against the development of cutaneous allodynia
    • Burstein R, Collins B, Jakubowski M. Defeating migraine pain with triptans: a race against the development of cutaneous allodynia. Ann Neurol 2004; 55 (1): 19-26
    • (2004) Ann Neurol , vol.55 , Issue.1 , pp. 19-26
    • Burstein, R.1    Collins, B.2    Jakubowski, M.3
  • 13
    • 0029120324 scopus 로고
    • Migraine symptoms: Results of a survey of self-reported migraineurs
    • Silberstein SD. Migraine symptoms: results of a survey of self-reported migraineurs. Headache 1995; 35 (7): 387-96
    • (1995) Headache , vol.35 , Issue.7 , pp. 387-396
    • Silberstein, S.D.1
  • 14
    • 0031752781 scopus 로고    scopus 로고
    • Migraine therapy: Development and testing of a patient preference questionnaire
    • Caro G, Caro JJ, O'Brien JA, et al. Migraine therapy: development and testing of a patient preference questionnaire. Headache 1998; 38 (8): 602-7
    • (1998) Headache , vol.38 , Issue.8 , pp. 602-607
    • Caro, G.1    Caro, J.J.2    O'Brien, J.A.3
  • 15
    • 0036169984 scopus 로고    scopus 로고
    • What do patients with migraine want from acute migraine treatment?
    • Lipton RB, Hamelsky SW, Dayno JM. What do patients with migraine want from acute migraine treatment? Headache 2002; 42 Suppl. 1: S3-9
    • (2002) Headache , vol.42 , Issue.SUPPL. 1
    • Lipton, R.B.1    Hamelsky, S.W.2    Dayno, J.M.3
  • 16
    • 0034453788 scopus 로고    scopus 로고
    • Determinants of patient satisfaction with migraine therapy
    • Davies GM, Santanello N, Lipton R. Determinants of patient satisfaction with migraine therapy. Cephalalgia 2000; 20 (6): 554-60
    • (2000) Cephalalgia , vol.20 , Issue.6 , pp. 554-560
    • Davies, G.M.1    Santanello, N.2    Lipton, R.3
  • 17
    • 0036780470 scopus 로고    scopus 로고
    • Determinants of migraine-specific quality of life
    • Santanello NC, Davies G, Allen C, et al. Determinants of migraine-specific quality of life. Cephalalgia 2002; 22 (8): 680-5
    • (2002) Cephalalgia , vol.22 , Issue.8 , pp. 680-685
    • Santanello, N.C.1    Davies, G.2    Allen, C.3
  • 18
    • 17944364294 scopus 로고    scopus 로고
    • Preference comparison of rizatriptan odt 10-mg and sumatriptan 50-mg tablet in migraine
    • Loder E, Brandes JL, Silberstein S, et al. Preference comparison of rizatriptan odt 10-mg and sumatriptan 50-mg tablet in migraine. Headache 2001; 41 (8): 745-53
    • (2001) Headache , vol.41 , Issue.8 , pp. 745-753
    • Loder, E.1    Brandes, J.L.2    Silberstein, S.3
  • 19
    • 0025766622 scopus 로고
    • Methodology of clinical trials of sumatriptan in migraine and cluster headache
    • Pilgrim AJ. Methodology of clinical trials of sumatriptan in migraine and cluster headache. Eur Neurol 1991; 31 (5): 295-9
    • (1991) Eur Neurol , vol.31 , Issue.5 , pp. 295-299
    • Pilgrim, A.J.1
  • 20
    • 0034483344 scopus 로고    scopus 로고
    • Guidelines for controlled trials of drugs in migraine
    • second edition
    • Tfelt-Hansen P, Block G, Dahl̈of C, et al. Guidelines for controlled trials of drugs in migraine: second edition. Cephalalgia 2000; 20 (9): 765-86
    • (2000) Cephalalgia , vol.20 , Issue.9 , pp. 765-786
    • Tfelt-Hansen, P.1    Block, G.2    Dahl̈of, C.3
  • 21
    • 0036780166 scopus 로고    scopus 로고
    • 1B/1D agonists) in migraine: Detailed results and methods of a meta-analysis of 53 trials
    • 1B/1D agonists) in migraine: detailed results and methods of a meta-analysis of 53 trials. Cephalalgia 2002; 22: 633-58
    • (2002) Cephalalgia , vol.22 , pp. 633-658
    • Ferrari, M.D.1    Goadsby, P.J.2    Roon, K.I.3
  • 22
    • 0345095460 scopus 로고    scopus 로고
    • Cost-effectiveness of almotriptan and rizatriptan in the treatment of acute migraine
    • Williams P, Reeder CE. Cost-effectiveness of almotriptan and rizatriptan in the treatment of acute migraine. Clin Ther 2003; 25 (11): 2903-19
    • (2003) Clin Ther , vol.25 , Issue.11 , pp. 2903-2919
    • Williams, P.1    Reeder, C.E.2
  • 23
    • 4043085035 scopus 로고    scopus 로고
    • A comparison of the cost-effectiveness of almotriptan and sumatriptan in the treatment of acute migraine using a composite efficacy/tolerability end point
    • Williams P, Reeder CE. A comparison of the cost-effectiveness of almotriptan and sumatriptan in the treatment of acute migraine using a composite efficacy/tolerability end point. J Manag Care Pharm 2004; 10 (3): 259-65
    • (2004) J Manag Care Pharm , vol.10 , Issue.3 , pp. 259-265
    • Williams, P.1    Reeder, C.E.2
  • 24
    • 33644877853 scopus 로고    scopus 로고
    • Focus on trial endpoints of clinical relevance and the use of almotriptan for the acute treatment of migraine
    • Sandrini G, Dahlof CG, Mathew N, et al. Focus on trial endpoints of clinical relevance and the use of almotriptan for the acute treatment of migraine. Int J Clin Pract 2005; 59 (11): 1356-65
    • (2005) Int J Clin Pract , vol.59 , Issue.11 , pp. 1356-1365
    • Sandrini, G.1    Dahlof, C.G.2    Mathew, N.3
  • 25
    • 33846117289 scopus 로고    scopus 로고
    • Techniques of water resources investigations
    • US Geological Survey, Helsel DR, Hirsch RM, editors Statistical methods in water resources [online, Available from URL:, Accessed Aug 18
    • US Geological Survey. Techniques of water resources investigations: book 4. Alternative methods for regression. In: Helsel DR, Hirsch RM, editors Statistical methods in water resources [online]. Available from URL: http://water.usgs.gov/pubs/twri/twri4a3/pdf/chapter10new.pdf [Accessed 2004 Aug 18]
    • (2004) book 4. Alternative methods for regression
  • 26
    • 33846094647 scopus 로고    scopus 로고
    • National Institute of Standards and Technology, Information Technology Laboratory. NIST/SEMATECH e-handbook of statistical methods [online, Available from URL:, Accessed Aug 18
    • Prins J, McCormack D, Michelson D, et al. What are outliers in the data? In: National Institute of Standards and Technology, Information Technology Laboratory. NIST/SEMATECH e-handbook of statistical methods [online]. Available from URL: http://www.itl.nist.gov/div898/handbook/prc/section1/prc16.htm [Accessed 2004 Aug 18]
    • (2004) What are outliers in the data? In
    • Prins, J.1    McCormack, D.2    Michelson, D.3
  • 27
    • 2942519284 scopus 로고    scopus 로고
    • Triptans and CNS side-effects: Pharmacokinetic and metabolic mechanisms
    • Dodick D, Martin V. Triptans and CNS side-effects: pharmacokinetic and metabolic mechanisms. Cephalalgia 2004; 24 (6): 417-24
    • (2004) Cephalalgia , vol.24 , Issue.6 , pp. 417-424
    • Dodick, D.1    Martin, V.2
  • 28
    • 11844274555 scopus 로고    scopus 로고
    • Correlation between lipophilicity and triptan outcomes
    • Pascual J, Munoz P. Correlation between lipophilicity and triptan outcomes. Headache 2005; 45 (1): 3-6
    • (2005) Headache , vol.45 , Issue.1 , pp. 3-6
    • Pascual, J.1    Munoz, P.2
  • 29
    • 0003951396 scopus 로고    scopus 로고
    • Oxford Centre for Evidence-Based Medicine, online, Available from URL:, Accessed May 1
    • Oxford Centre for Evidence-Based Medicine. Levels of evidence and grades of recommendation [online]. Available from URL: http://www.cebm.net/ levels_of_evidence.asp [Accessed 2004 May 1]
    • (2004) Levels of evidence and grades of recommendation
  • 30
    • 0037275120 scopus 로고    scopus 로고
    • Tolerability of the triptans: Clinical implications
    • Nappi G, Sandrini G, Sances G. Tolerability of the triptans: clinical implications. Drug Saf 2003; 26 (2): 93-107
    • (2003) Drug Saf , vol.26 , Issue.2 , pp. 93-107
    • Nappi, G.1    Sandrini, G.2    Sances, G.3
  • 31
    • 8844285858 scopus 로고    scopus 로고
    • Assessment of adverse events associated with triptans - methods of assessment influence the results
    • Sheftell FD, Feleppa M, Tepper SJ, et al. Assessment of adverse events associated with triptans - methods of assessment influence the results. Headache 2004; 44 (10): 978-82
    • (2004) Headache , vol.44 , Issue.10 , pp. 978-982
    • Sheftell, F.D.1    Feleppa, M.2    Tepper, S.J.3
  • 32
    • 0036166346 scopus 로고    scopus 로고
    • A long-term open-label study of oral almotriptan 12.5mg for the treatment of acute migraine attacks
    • Mathew N. A long-term open-label study of oral almotriptan 12.5mg for the treatment of acute migraine attacks. Headache 2002; 42: 32-40
    • (2002) Headache , vol.42 , pp. 32-40
    • Mathew, N.1
  • 33
    • 0034995238 scopus 로고    scopus 로고
    • Tolerability and efficacy of almotriptan in the long-term treatment of migraine
    • Pascual J, Falk R, Docekal R, et al. Tolerability and efficacy of almotriptan in the long-term treatment of migraine. Eur Neurol 2001; 45 (4): 206-13
    • (2001) Eur Neurol , vol.45 , Issue.4 , pp. 206-213
    • Pascual, J.1    Falk, R.2    Docekal, R.3
  • 34
    • 0034970004 scopus 로고    scopus 로고
    • Oral almotriptan vs oral sumatriptan in the abortive treatment of migraine: A double-blind, randomized, parallel-group, optimum-dose comparison
    • Spierings EL, Gomez-Mancilla B, Grosz DE, et al. Oral almotriptan vs oral sumatriptan in the abortive treatment of migraine: a double-blind, randomized, parallel-group, optimum-dose comparison. Arch Neurol 2001; 58 (6): 944-50
    • (2001) Arch Neurol , vol.58 , Issue.6 , pp. 944-950
    • Spierings, E.L.1    Gomez-Mancilla, B.2    Grosz, D.E.3
  • 35
    • 14644406579 scopus 로고    scopus 로고
    • Relationship between sustained pain-free and adverse events: A comparison of almotriptan 12.5mg and other oral triptans in acute migraine
    • Dodick DW, Sandrini G. Relationship between sustained pain-free and adverse events: a comparison of almotriptan 12.5mg and other oral triptans in acute migraine. Headache 2004; 44: 468-9
    • (2004) Headache , vol.44 , pp. 468-469
    • Dodick, D.W.1    Sandrini, G.2
  • 37
    • 0032890561 scopus 로고    scopus 로고
    • Reporting risks and benefits of therapy by use of the concepts of unqualified success and unmitigated failure: Applications to highly cited trials in cardiovascular medicine
    • Mancini GB, Schulzer M. Reporting risks and benefits of therapy by use of the concepts of unqualified success and unmitigated failure: applications to highly cited trials in cardiovascular medicine. Circulation 1999; 99 (3): 377-83
    • (1999) Circulation , vol.99 , Issue.3 , pp. 377-383
    • Mancini, G.B.1    Schulzer, M.2
  • 38
    • 0029763906 scopus 로고    scopus 로고
    • Unqualified success' and 'unmitigated failure': Number-needed-to-treat-related concepts for assessing treatment efficacy in the presence of treatment-induced adverse events
    • Schulzer M, Mancini GB. 'Unqualified success' and 'unmitigated failure': number-needed-to-treat-related concepts for assessing treatment efficacy in the presence of treatment-induced adverse events. Int J Epidemiol 1996; 25 (4): 704-12
    • (1996) Int J Epidemiol , vol.25 , Issue.4 , pp. 704-712
    • Schulzer, M.1    Mancini, G.B.2
  • 39
    • 33744517586 scopus 로고    scopus 로고
    • Review of clinical trials using early acute intervention with oral triptans for migraine management
    • Dowson AJ, Mathew NT, Pascual J. Review of clinical trials using early acute intervention with oral triptans for migraine management. Int J Clin Pract 2006; 60 (6): 698-706
    • (2006) Int J Clin Pract , vol.60 , Issue.6 , pp. 698-706
    • Dowson, A.J.1    Mathew, N.T.2    Pascual, J.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.