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Volumn 18, Issue 1, 2007, Pages 103-112

A sensitized screen of N-ethyl-N-nitrosourea-mutagenized mice identifies dominant mutants predisposed to diabetic nephropathy

Author keywords

[No Author keywords available]

Indexed keywords

ALBUMIN; CREATININE; ETHYLNITROSOUREA; INULIN; UREA;

EID: 33846037745     PISSN: 10466673     EISSN: None     Source Type: Journal    
DOI: 10.1681/ASN.2006020164     Document Type: Article
Times cited : (16)

References (50)
  • 1
    • 4344652866 scopus 로고    scopus 로고
    • Projecting the United States ESRD population: Issues regarding treatment of patients with ESRD
    • Szczech LA, Lazar IL: Projecting the United States ESRD population: Issues regarding treatment of patients with ESRD. Kidney Int Suppl 90: S3-S7, 2004
    • (2004) Kidney Int Suppl , vol.90
    • Szczech, L.A.1    Lazar, I.L.2
  • 2
    • 0042023727 scopus 로고    scopus 로고
    • Racial differences in diabetic nephropathy, cardiovascular disease, and mortality in a national population of veterans
    • Young BA, Maynard C, Boyko EJ: Racial differences in diabetic nephropathy, cardiovascular disease, and mortality in a national population of veterans. Diabetes Care 26: 2392-2399, 2003
    • (2003) Diabetes Care , vol.26 , pp. 2392-2399
    • Young, B.A.1    Maynard, C.2    Boyko, E.J.3
  • 3
    • 0033970580 scopus 로고    scopus 로고
    • Cardiovascular morbidity and early mortality cluster in parents of type 1 diabetic patients with diabetic nephropathy
    • Tarnow L, Rossing P, Nielsen FS, Fagerudd JA, Poirier O, Parving HH: Cardiovascular morbidity and early mortality cluster in parents of type 1 diabetic patients with diabetic nephropathy. Diabetes Care 23: 30-33, 2000
    • (2000) Diabetes Care , vol.23 , pp. 30-33
    • Tarnow, L.1    Rossing, P.2    Nielsen, F.S.3    Fagerudd, J.A.4    Poirier, O.5    Parving, H.H.6
  • 4
    • 0029043874 scopus 로고
    • Glycosylated hemoglobin and the risk of microalbuminuria in patients with insulin dependent diabetes mellitus
    • Krolewski AS, Laffel LM, Krolewski M, Quinn M, Warram JH: Glycosylated hemoglobin and the risk of microalbuminuria in patients with insulin dependent diabetes mellitus. N Engl J Med 332: 1251-1255, 1995
    • (1995) N Engl J Med , vol.332 , pp. 1251-1255
    • Krolewski, A.S.1    Laffel, L.M.2    Krolewski, M.3    Quinn, M.4    Warram, J.H.5
  • 5
    • 0024559825 scopus 로고
    • Familial clustering of diabetic kidney disease. Evidence for genetic susceptibility to diabetic nephropathy
    • Seaquist ER, Goetz FC, Rich S, Barbosa J: Familial clustering of diabetic kidney disease. Evidence for genetic susceptibility to diabetic nephropathy. N Engl J Med 320: 1161-1165, 1989
    • (1989) N Engl J Med , vol.320 , pp. 1161-1165
    • Seaquist, E.R.1    Goetz, F.C.2    Rich, S.3    Barbosa, J.4
  • 6
    • 0032895814 scopus 로고    scopus 로고
    • Genetics of diabetic nephropathy: Evidence for major and minor gene effects
    • Krolewski AS: Genetics of diabetic nephropathy: Evidence for major and minor gene effects. Kidney Int 55: 1582-1596, 1999
    • (1999) Kidney Int , vol.55 , pp. 1582-1596
    • Krolewski, A.S.1
  • 10
    • 24144496134 scopus 로고    scopus 로고
    • Characterization of susceptibility if inbred mouse strains to diabetic nephropathy
    • Qi Z, Fujita H, Jin J, Davis LS, Wang Y, Fogo AB, Breyer MD: Characterization of susceptibility if inbred mouse strains to diabetic nephropathy. Diabetes 54: 2628-2637, 2005
    • (2005) Diabetes , vol.54 , pp. 2628-2637
    • Qi, Z.1    Fujita, H.2    Jin, J.3    Davis, L.S.4    Wang, Y.5    Fogo, A.B.6    Breyer, M.D.7
  • 12
    • 4444374983 scopus 로고    scopus 로고
    • Diabetic nephropathy is markedly enhanced in mice lacking the bradykinin B2 receptor
    • Kakoki M, Takahashi N, Jennette JC, Smithies O: Diabetic nephropathy is markedly enhanced in mice lacking the bradykinin B2 receptor. Proc Natl Acad Sci U S A 101: 13302-13305, 2004
    • (2004) Proc Natl Acad Sci U S A , vol.101 , pp. 13302-13305
    • Kakoki, M.1    Takahashi, N.2    Jennette, J.C.3    Smithies, O.4
  • 15
    • 0034425606 scopus 로고    scopus 로고
    • The roads from phenotyping variation to gene discovery: Mutagenesis versus QTLs
    • Nadeau JH, Frankel WN: The roads from phenotyping variation to gene discovery: Mutagenesis versus QTLs. Nat Genet 25: 381-384, 2000
    • (2000) Nat Genet , vol.25 , pp. 381-384
    • Nadeau, J.H.1    Frankel, W.N.2
  • 16
    • 0033866043 scopus 로고    scopus 로고
    • Sequence-based analysis of mutagenized mice
    • Beier DR: Sequence-based analysis of mutagenized mice. Mamm Genome 11: 594-597, 2000
    • (2000) Mamm Genome , vol.11 , pp. 594-597
    • Beier, D.R.1
  • 17
    • 85190712053 scopus 로고    scopus 로고
    • Nolan PM, Peters J, Strivens M, Rogers D, Hagan J, Spurr N, Gray IC, Vizor L, Brooker D, Whitehill E, Washbourne R, Hough T, Greenaway S, Hewitt M, Liu X, McCormack X, Pickford K, Selley R, Wells C, Tymowska-Lalanne Z, Roby P, Glenister P, Thornton C, Thaung C, Stevenson J-A, Arkell R, Mburu P, Hardisty R, Kiernan A, Erven A, Steel KP, Voegeling S, Guenet J-L, Nickols C, Sadri R, Naase M, Isaacs A, Davies K, Browne M, Fisher EMC, Martin J, Rastan S, Brown SDM, Hunter J: A systematic, genome wide, phenotype-driven mutagenesis program for gene function studies in the mouse. Nat Genet 25: 440-443, 2000
    • Nolan PM, Peters J, Strivens M, Rogers D, Hagan J, Spurr N, Gray IC, Vizor L, Brooker D, Whitehill E, Washbourne R, Hough T, Greenaway S, Hewitt M, Liu X, McCormack X, Pickford K, Selley R, Wells C, Tymowska-Lalanne Z, Roby P, Glenister P, Thornton C, Thaung C, Stevenson J-A, Arkell R, Mburu P, Hardisty R, Kiernan A, Erven A, Steel KP, Voegeling S, Guenet J-L, Nickols C, Sadri R, Naase M, Isaacs A, Davies K, Browne M, Fisher EMC, Martin J, Rastan S, Brown SDM, Hunter J: A systematic, genome wide, phenotype-driven mutagenesis program for gene function studies in the mouse. Nat Genet 25: 440-443, 2000
  • 18
    • 85190699642 scopus 로고    scopus 로고
    • Hrabe de Angelis M, Flaswinkel H, Fuchs H, Rathkolb B, Soewarto D, Marschall S, Heffner S, Pargent W, Wuensch K, Jung M, Reis A, Richter T, Alessandrini A, Jakob T, Fuchs E, Kolb H, Kremmer E, Schaeble K, Rollinski B, Roscher A, Peters C, Meitinger T, Strom T, Steckler T, Holsboer F, Klopstock T, Gekeler F, Schindewolf C, Jung T, Avraham K, Behrendt H, Ring J, Zimmer A, Schughart K, Pfeffer K, Wolf E, Balling R: Genome-wide, large-scale production of mutant mice by ENU mutagenesis. Nat Genet 25: 444-447, 2000
    • Hrabe de Angelis M, Flaswinkel H, Fuchs H, Rathkolb B, Soewarto D, Marschall S, Heffner S, Pargent W, Wuensch K, Jung M, Reis A, Richter T, Alessandrini A, Jakob T, Fuchs E, Kolb H, Kremmer E, Schaeble K, Rollinski B, Roscher A, Peters C, Meitinger T, Strom T, Steckler T, Holsboer F, Klopstock T, Gekeler F, Schindewolf C, Jung T, Avraham K, Behrendt H, Ring J, Zimmer A, Schughart K, Pfeffer K, Wolf E, Balling R: Genome-wide, large-scale production of mutant mice by ENU mutagenesis. Nat Genet 25: 444-447, 2000
  • 19
    • 0032918044 scopus 로고    scopus 로고
    • A mutation in the insulin 2 gene induces diabetes with severe pancreatic beta-cell dysfunction in the Mody mouse
    • Wang J, Takeuchi T, Tanaka S, Kubo S-K, Kayo T, Lu D, Takata K, Koizumi A, Izumi T: A mutation in the insulin 2 gene induces diabetes with severe pancreatic beta-cell dysfunction in the Mody mouse. J Clin Invest 103: 27-37, 1999
    • (1999) J Clin Invest , vol.103 , pp. 27-37
    • Wang, J.1    Takeuchi, T.2    Tanaka, S.3    Kubo, S.-K.4    Kayo, T.5    Lu, D.6    Takata, K.7    Koizumi, A.8    Izumi, T.9
  • 21
    • 0031727960 scopus 로고    scopus 로고
    • Saphenous vein puncture for blood sampling of the mouse, rat, hamster, gerbil, guinea pig, ferret and mink
    • Hem A, Smith AJ, Solberg P: Saphenous vein puncture for blood sampling of the mouse, rat, hamster, gerbil, guinea pig, ferret and mink. Lab Anim 32: 364-368, 1998
    • (1998) Lab Anim , vol.32 , pp. 364-368
    • Hem, A.1    Smith, A.J.2    Solberg, P.3
  • 22
    • 0032916919 scopus 로고    scopus 로고
    • A simple, nonradioactive method for evaluating single-nephron filtration rate using FITC-inulin
    • Lorenz JN, Gruenstein E: A simple, nonradioactive method for evaluating single-nephron filtration rate using FITC-inulin. Am J Physiol 276: F172-F177, 1999
    • (1999) Am J Physiol , vol.276
    • Lorenz, J.N.1    Gruenstein, E.2
  • 23
    • 1242306709 scopus 로고    scopus 로고
    • Serial determination of glomerular filtration rate in conscious mice using FITC-inulin clearance
    • Qi Z, Whitt I, Mehta A, Jin J, Zhao M: Harris RC, Fogo AB, Breyer MD: Serial determination of glomerular filtration rate in conscious mice using FITC-inulin clearance. Am J Physiol 286: 590-596, 2004
    • (2004) Am J Physiol , vol.286 , pp. 590-596
    • Qi, Z.1    Whitt, I.2    Mehta, A.3    Jin, J.4    Zhao, M.5    Harris, R.C.6    Fogo, A.B.7    Breyer, M.D.8
  • 24
    • 2342570276 scopus 로고    scopus 로고
    • Utility of endogenous creatinine clearance as a measure of renal function in mice
    • Dunn SR, Qi Z: Bottinger EP, Breyer MD: Utility of endogenous creatinine clearance as a measure of renal function in mice. Kidney Int 56: 1959-1967, 2004
    • (2004) Kidney Int , vol.56 , pp. 1959-1967
    • Dunn, S.R.1    Qi, Z.2    Bottinger, E.P.3    Breyer, M.D.4
  • 25
    • 0021179653 scopus 로고
    • Mesangial immune injury, hypertension and progressive glomerular damage in Dahl rats
    • Raji L, Azar S, Keane W: Mesangial immune injury, hypertension and progressive glomerular damage in Dahl rats. Kidney Int 26: 137-143, 1984
    • (1984) Kidney Int , vol.26 , pp. 137-143
    • Raji, L.1    Azar, S.2    Keane, W.3
  • 26
    • 0024463832 scopus 로고
    • Disparities in incidence of diabetic end-stage renal disease according to race and type of diabetes
    • Cowie CC, Port FK, Wolf RA, Savage PJ, Moll PP, Hawthorne VM: Disparities in incidence of diabetic end-stage renal disease according to race and type of diabetes. N Engl J Med 321: 1074-1079, 1989
    • (1989) N Engl J Med , vol.321 , pp. 1074-1079
    • Cowie, C.C.1    Port, F.K.2    Wolf, R.A.3    Savage, P.J.4    Moll, P.P.5    Hawthorne, V.M.6
  • 27
    • 0029994018 scopus 로고    scopus 로고
    • Familial factors determine the development of diabetic nephropathy in patients with IDDM
    • Quinn M, Angelico MC, Warram JH, Krolewski AS: Familial factors determine the development of diabetic nephropathy in patients with IDDM. Diabetologia 39: 940-945, 1996
    • (1996) Diabetologia , vol.39 , pp. 940-945
    • Quinn, M.1    Angelico, M.C.2    Warram, J.H.3    Krolewski, A.S.4
  • 30
    • 33644681167 scopus 로고    scopus 로고
    • Risk of diabetic nephropathy in type 1 diabetes is associated with functional polymorphisms in RANTES receptor gene (CCR5): A sex-specific effect
    • Mlynarski WM, Placha GP, Wolkow PP, Bochenski JP, Warram JH, Krolewski AS: Risk of diabetic nephropathy in type 1 diabetes is associated with functional polymorphisms in RANTES receptor gene (CCR5): A sex-specific effect. Diabetes 54: 3331-3335, 2005
    • (2005) Diabetes , vol.54 , pp. 3331-3335
    • Mlynarski, W.M.1    Placha, G.P.2    Wolkow, P.P.3    Bochenski, J.P.4    Warram, J.H.5    Krolewski, A.S.6
  • 32
    • 0030907296 scopus 로고    scopus 로고
    • A novel locus, Mody4, distal to D7Mit189 on chromosome 7 determines early-onset NIDDM in nonobese C57BL/6 (Akita) mutant mice
    • Yoshioka M, Kayo T, Ikeda T, Koizumi A: A novel locus, Mody4, distal to D7Mit189 on chromosome 7 determines early-onset NIDDM in nonobese C57BL/6 (Akita) mutant mice. Diabetes 46: 887-894, 1997
    • (1997) Diabetes , vol.46 , pp. 887-894
    • Yoshioka, M.1    Kayo, T.2    Ikeda, T.3    Koizumi, A.4
  • 33
    • 0033850165 scopus 로고    scopus 로고
    • The need for earlier predictors of diabetic nephropathy risk: Is albumin excretion rate sufficient?
    • Caramori ML, Fioretto P, Mauer M: The need for earlier predictors of diabetic nephropathy risk: Is albumin excretion rate sufficient? Diabetes 49: 1399-1408, 2000
    • (2000) Diabetes , vol.49 , pp. 1399-1408
    • Caramori, M.L.1    Fioretto, P.2    Mauer, M.3
  • 34
    • 0024846202 scopus 로고
    • The effect of blood pressure intervention on renal function in insulin-dependent diabetes
    • Mogensen CE: The effect of blood pressure intervention on renal function in insulin-dependent diabetes. Diabetes Metab 15: 343-351, 1989
    • (1989) Diabetes Metab , vol.15 , pp. 343-351
    • Mogensen, C.E.1
  • 35
    • 0037820396 scopus 로고    scopus 로고
    • Microalbuminuria and hypertension with focus on type 1 and type 2 diabetes
    • Mogensen CE: Microalbuminuria and hypertension with focus on type 1 and type 2 diabetes. J Intern Med 254: 45-66, 2003
    • (2003) J Intern Med , vol.254 , pp. 45-66
    • Mogensen, C.E.1
  • 38
    • 0034756107 scopus 로고    scopus 로고
    • Increased expression of glutathione S-transferase in renal proximal tubules in the early stages of diabetes: A study of type-2 diabetes in the Akita mouse model
    • Fujita H, Haseyama T, Kayo T, Nozaki J, Wada Y, Ito S, Koizumi A: Increased expression of glutathione S-transferase in renal proximal tubules in the early stages of diabetes: A study of type-2 diabetes in the Akita mouse model. Exp Nephrol 9: 380-386, 2001
    • (2001) Exp Nephrol , vol.9 , pp. 380-386
    • Fujita, H.1    Haseyama, T.2    Kayo, T.3    Nozaki, J.4    Wada, Y.5    Ito, S.6    Koizumi, A.7
  • 40
    • 0035122471 scopus 로고    scopus 로고
    • Improved diabetic syndrome in C57BL/KsJ-db/db mice by oral administration of the Na+-glucose cotransporter inhibitor T-1095
    • Arakawa K, Ishihara T, Oku A, Nawano M, Ueta K, Kitamura K, Matsumoto M, Saito A: Improved diabetic syndrome in C57BL/KsJ-db/db mice by oral administration of the Na+-glucose cotransporter inhibitor T-1095. Br J Pharmacol 132: 578-586, 2001
    • (2001) Br J Pharmacol , vol.132 , pp. 578-586
    • Arakawa, K.1    Ishihara, T.2    Oku, A.3    Nawano, M.4    Ueta, K.5    Kitamura, K.6    Matsumoto, M.7    Saito, A.8
  • 42
    • 3142598798 scopus 로고    scopus 로고
    • A cyclooxygenase-1 (COX-1) selective inhibitor improves diabetic nephropathy in mice [Abstract]
    • Tchekneva EE, Qi Z, Polosukhina D, Jin J, Breyer MD: A cyclooxygenase-1 (COX-1) selective inhibitor improves diabetic nephropathy in mice [Abstract]. J Am Soc Nephrol 14: 393A, 2003
    • (2003) J Am Soc Nephrol , vol.14
    • Tchekneva, E.E.1    Qi, Z.2    Polosukhina, D.3    Jin, J.4    Breyer, M.D.5
  • 44
    • 0024510483 scopus 로고
    • Glomerular lesions and urinary albumin excretion in type 1 diabetes without overt proteinuria
    • Chavers BM, Bilous RW, Ellis EN, Steffes MW, Mauer SM: Glomerular lesions and urinary albumin excretion in type 1 diabetes without overt proteinuria. N Engl J Med 320: 966-970, 1989
    • (1989) N Engl J Med , vol.320 , pp. 966-970
    • Chavers, B.M.1    Bilous, R.W.2    Ellis, E.N.3    Steffes, M.W.4    Mauer, S.M.5
  • 45
    • 29644434152 scopus 로고    scopus 로고
    • A stereological study of the renal glomerular vasculature in the db/db mouse model of diabetic nephropathy
    • Guo M, Ricardo SD, Deane JA, Shi M, McEwen LC, Bertram JF: A stereological study of the renal glomerular vasculature in the db/db mouse model of diabetic nephropathy. J Anat 207: 813-821, 2005
    • (2005) J Anat , vol.207 , pp. 813-821
    • Guo, M.1    Ricardo, S.D.2    Deane, J.A.3    Shi, M.4    McEwen, L.C.5    Bertram, J.F.6
  • 47
    • 9444290163 scopus 로고    scopus 로고
    • Diabetic nephropathy
    • edited by Porte D, Sherwin RS, Baron A, New York, McGraw Hill
    • DeFronzo RA: Diabetic nephropathy. In: Ellenberg & Rifkin's Diabetes Mellitus, edited by Porte D, Sherwin RS, Baron A, New York, McGraw Hill, 2004, pp 723-745
    • (2004) Ellenberg & Rifkin's Diabetes Mellitus , pp. 723-745
    • DeFronzo, R.A.1
  • 48
    • 0006535220 scopus 로고
    • Hypercholesterolemia: A determinant of renal function loss and deaths in IDDM patients with nephropathy
    • Krolewski AS, Warram JH, Christlieb AR: Hypercholesterolemia: A determinant of renal function loss and deaths in IDDM patients with nephropathy. Kidney Int Suppl 45: S125-S131, 1994
    • (1994) Kidney Int Suppl , vol.45
    • Krolewski, A.S.1    Warram, J.H.2    Christlieb, A.R.3


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