Value of the HLA-DRB1 shared epitope for predicting radiographic damage in rheumatoid arthritis depends on the individual patient risk profile

Journal of Rheumatology

Volumn 33, Issue 12, 2006, Pages 2383-2389

  Janssens, A Cecile J W ^a   Steyerberg, Ewout W ^a   Jiang, Yebin ^b   Habbema, J Dik F ^a   Van Duijn, Cornelia M ^a   Criswell, Lindsey A ^b,c  

^a ERASMUS MEDICAL CENTER   (Netherlands)

^b UNIVERSITY OF CALIFORNIA   (United States)

^c UNIVERSITY OF CALIFORNIA   (United States)

Author keywords

Genetic testing; HLA DRB1 shared epitope; Prediction models; Radiographic damage; Rheumatoid arthritis

Indexed keywords

EPITOPE; HLA DR ANTIGEN; RHEUMATOID FACTOR;

ARTICLE; EUROPEAN AMERICAN; FEMALE; GENETIC SCREENING; GENOTYPE; HUMAN; JOINT DESTRUCTION; MAJOR CLINICAL STUDY; PREDICTION; PRIORITY JOURNAL; RHEUMATOID ARTHRITIS; RISK ASSESSMENT; STATISTICAL MODEL;

ADULT; ARTHRITIS, RHEUMATOID; ARTHROGRAPHY; EPITOPES; FEMALE; FOLLOW-UP STUDIES; GENETIC MARKERS; GENETIC PREDISPOSITION TO DISEASE; HEALTH STATUS; HISTOCOMPATIBILITY TESTING; HLA-DR ANTIGENS; HUMANS; JOINTS; ODDS RATIO; PREDICTIVE VALUE OF TESTS; PROGNOSIS; RHEUMATOLOGY; RISK FACTORS; SEVERITY OF ILLNESS INDEX;

EID: 33846034898     PISSN: 0315162X     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (22)

1. German JD, Criswell LA. The shared epitope and severity of rheumatoid arthritis. Rheum Dis Clin North Am 2002;28:59-78.
2. Meyer JM, Evans TI, Small RE, et al. HLA-DRB1 genotype influences risk for and severity of rheumatoid arthritis. J Rheumatol 1999;26:1024-34.
3. Moreno I, Valenzuela A, Garcia A, Yelamos J, Sanchez B, Hernanz W. Association of the shared epitope with radiological severity of rheumatoid arthritis. J Rheumatol 1996;23:6-9.
4. van Zeben D, Hazes JMW, Zwinderman AH, et al. Association of HLA-DR4 with a more progressive disease course in patients with rheumatoid arthritis. Results of a followup study. Arthritis Rheum 1991;34:822-30.
5. German JD, Lum RF, Chen JJ, Suarez-Almazor ME, Thomson G, Criswell LA. Impact of shared epitope genotype and ethnicity on erosive disease: a meta-analysis of 3,240 rheumatoid arthritis patients. Arthritis Rheum 2004;50:400-12.
6. Chen JJ, Mu H, Jiang Y, King M-C, Thomson G, Criswell LA. The clinical usefulness of genetic information for predicting radiographic damage in rheumatoid arthritis. J Rheumatol 2002;29:2068-73.
7. Kaltenhauser S, Wagner U, Schuster E, et al. Immunogenetic markers and seropositivity predict radiological progression in early rheumatoid arthritis independent of disease activity. J Rheumatol 2001;28:735-44.
8. MacGregor A, Oilier WER, Thomson W, Jawaheer D, Silman A. HLA-DRB1 *0401/0404 genotype and rheumatoid arthritis: increased association in men, young age at onset, and disease severity. J Rheumatol 1995;22:1032-6.
9. Del Rincon I, Battafarano DF, Arroyo RA, Murphy FT, Fischbach M, Escalante A. Ethnic variation in the clinical manifestations of rheumatoid arthritis: role of HLA-DRB1 alleles. Arthritis Rheum 2003;49:200-8.
10. Olsen NJ, Callahan LF, Brooks RH, et al. Associations of HLA-DR4 with rheumatoid factor and radiographic severity in rheumatoid arthritis. Am J Med 1988;84:257-64.
11. Janssens ACJW, Deng Y, Borsboom GJJM, Eijkemans MJC, Habbema JDF, Steyerberg EW. A new logistic regression approach for the evaluation of diagnostic test results. Med Decis Making 2005;25:168-77.
12. Yelin EH, Henke CJ, Kramer JS, Nevitt MC, Shearn M, Epstein WV. A comparison of the treatment of rheumatoid arthritis in health maintenance organizations and fee-for-service practices. N Engl J Med 1985;312:962-7.
13. Genant HK, Jiang Y Peterfy C, Lu Y, Redei J, Countryman PJ. Assessment of rheumatoid arthritis using a modified scoring method on digitized and original radiographs. Arthritis Rheum 1998;41:1583-90.
14. Bidwell JL, Bignon JD. DNA-RFLP methods and interpretation scheme for HLA-DR and DQ typing. Eur J Immunogenetics 1991;18:5-22.
15. Petersdorf EW, Smith AG, Mickelson EM, Martin PJ, Hansen JA. Ten HLA-DR4 alleles defined by sequence polymorphisms within the DRB1 first domain. Immunogenetics 1991;33:267-75.
16. Ota M, Seki T, Fukushima H, Tsuji K, Inoko H. HLA-DRB1 genotyping by modified PCR-RFLP method combined with group-specific primers. Tissue Antigens 1992;39:187-202.
17. Sherrer YS, Bloch DA, Mitchell DM, Roth SH, Wolfe F, Fries JF. Disability in rheumatoid arthritis: comparison of prognostic factors across three populations. J Rheumatol 1987;14:705-9.
18. Alarcon GS. Predictive factors in rheumatoid arthritis. Am J Med 1997;103:19S-24S.
19. van der Heijde DM, van Riel PL, van Leeuwen MA, van't Hof MA, van Rijswijk MH, van de Putte LB. Prognostic factors for radiographic damage and physical disability in early rheumatoid arthritis. A prospective follow-up study of 147 patients. Br J Rheumatol 1992;31:519-25.
20. Combe B, Dougados M, Goupille P, et al. Prognostic factors for radiographic damage in early rheumatoid arthritis: a multiparameter prospective study. Arthritis Rheum 2001;44:1736-43.
21. Guillemin F, Gerard N, van Leeuwen M, Smedstad LM, Kvien TK, van den Heuvel W. Prognostic factors for joint destruction in rheumatoid arthritis: a prospective longitudinal study of 318 patients. J Rheumatol 2003;30:2585-9.
22. Drossaers-Bakker KW, Zwinderman AH, Vlieland TP, et al. Long-term outcome in rheumatoid arthritis: a simple algorithm of baseline parameters can predict radiographic damage, disability, and disease course at 12-year followup. Arthritis Rheum 2002;47:383-90.