Potent inhibition of serum-stimulated responses in vascular smooth muscle cell proliferation by 2-chloro-3-(4-hexylphenyl)-amino-1,4-naphthoquinone, a newly synthesized 1,4-naphthoquinone derivative

Biological and Pharmaceutical Bulletin

Volumn 30, Issue 1, 2007, Pages 121-127

  Kim, Tack Joong ^a   Yun, Yeo Pyo ^a  

^a Chungbuk National University   (South Korea)

Author keywords

1,4 naphthoquinone; Atherosclerosis; Cell cycle; Proliferation

Indexed keywords

1,4 NAPHTHOQUINONE DERIVATIVE; 2 CHLORO 3 (4 HEXYLPHENYL) AMINO 1,4 NAPHTHOQUINONE; CYCLIN DEPENDENT KINASE INHIBITOR 1; CYCLIN DEPENDENT KINASE INHIBITOR 1B; DNA FRAGMENT; MESSENGER RNA; MITOGEN ACTIVATED PROTEIN KINASE 1; MITOGEN ACTIVATED PROTEIN KINASE 3; NQ 304; PROTEIN C FOS; PROTEIN KINASE B; TRANSCRIPTION FACTOR AP 1; UNCLASSIFIED DRUG;

ANIMAL CELL; APOPTOSIS; ARTICLE; ATHEROSCLEROSIS; CELL COUNT; CELL CYCLE ARREST; CELL CYCLE G0 PHASE; CELL CYCLE G1 PHASE; CELL DEATH; CELL GROWTH; CELL PROLIFERATION; CONTROLLED STUDY; COW; DNA BINDING; DNA SYNTHESIS; DOSE RESPONSE; DRUG INHIBITION; DRUG MECHANISM; DRUG SYNTHESIS; ENZYME ACTIVATION; ENZYME PHOSPHORYLATION; FETUS BLOOD; FLOW CYTOMETRY; NONHUMAN; PROTEIN BINDING; PROTEIN EXPRESSION; RAT; SMOOTH MUSCLE FIBER; STIMULUS RESPONSE; VASCULAR SMOOTH MUSCLE;

1-PHOSPHATIDYLINOSITOL 3-KINASE; ANIMALS; ANTIMITOTIC AGENTS; AORTA; ATHEROSCLEROSIS; CELL CYCLE; CELL PROLIFERATION; CELLS, CULTURED; DNA; DOSE-RESPONSE RELATIONSHIP, DRUG; EXTRACELLULAR SIGNAL-REGULATED MAP KINASES; MUSCLE, SMOOTH, VASCULAR; MYOCYTES, SMOOTH MUSCLE; NAPHTHOQUINONES; PROTO-ONCOGENE PROTEINS C-AKT; PROTO-ONCOGENE PROTEINS C-FOS; RATS; RNA, MESSENGER; SERUM; SIGNAL TRANSDUCTION; TRANSCRIPTION FACTOR AP-1;

EID: 33846034491     PISSN: 09186158     EISSN: 13475215     Source Type: Journal    
DOI: 10.1248/bpb.30.121     Document Type: Article

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