Bacterial proteins and CpG-rich extrachromosomal DNA in potential cancer therapy

Plasmid

Volumn 57, Issue 1, 2007, Pages 4-17

  Mahfouz, Magdy ^a   Hashimoto, Wataru ^a   Das Gupta, Tapas K ^a   Chakrabarty, Ananda M ^a  

^a UNIVERSITY OF ILLINOIS   (United States)

Author keywords

CpG rich DNA; Cupredoxins; Genomic islands

Indexed keywords

AZURIN; BACTERIAL DNA; BACTERIAL PROTEIN; CHEMOKINE; CPG OLIGODEOXYNUCLEOTIDE; CYTOKINE; DINUCLEOTIDE; DNA FRAGMENT; PROTEIN LAZ; TOLL LIKE RECEPTOR; TOLL LIKE RECEPTOR 9; UNCLASSIFIED DRUG;

ANTINEOPLASTIC ACTIVITY; APOPTOSIS; CANCER CELL; CANCER INHIBITION; CANCER REGRESSION; CANCER THERAPY; CELL KILLING; CPG ISLAND; CYTOKINE PRODUCTION; DNA TEMPLATE; HUMAN; HUMAN CELL; IMMUNOCOMPETENT CELL; NONHUMAN; POLYMERASE CHAIN REACTION; PROMOTER REGION; PROTEIN SECRETION; PSEUDOMONAS AERUGINOSA; QUORUM SENSING; RECEPTOR UPREGULATION; REVIEW; SEQUENCE HOMOLOGY; SYSTEMATIC REVIEW; WESTERN BLOTTING;

AMINO ACID SEQUENCE; ANTINEOPLASTIC AGENTS; AZURIN; BASE SEQUENCE; CELL LINE, TUMOR; CPG ISLANDS; DNA, BACTERIAL; HUMANS; MOLECULAR SEQUENCE DATA; NEOPLASMS; PSEUDOMONAS AERUGINOSA;

BACTERIA (MICROORGANISMS); PSEUDOMONAS AERUGINOSA;

EID: 33846004207     PISSN: 0147619X     EISSN: 10959890     Source Type: Journal    
DOI: 10.1016/j.plasmid.2006.11.001     Document Type: Review

References (58)

1. Burns D.L. Biochemistry of type IV secretion. Curr. Opin. Microbiol. 2 (1999) 25-29
2. Cascales E., and Christie P.J. The versatile bacterial type IV secretion systems. Nature Rev. Microbiol. 1 (2003) 137-149
3. Chakrabarty A.M. Microorganisms and cancer: quest for a therapy. J. Bacterial. 185 (2003) 2683-2686
4. Chaudhari A., Fialho A.M., Ratner D., Gupta P., Hong C.S., Kahali S., Yamada T., Haldar K., Murphy S., Cho W., Chauhan V.S., Das Gupta T.K., and Chakrabarty A.M. Azurin, Plasmodium falciparum malaria and HIV/AIDS: inhibition of parasitic and viral growth by azurin. Cell Cycle 5 (2006) 1642-1648
5. Courvalin P., and Davies J. Antimicrobials. Curr. Opin. Microbiol. 6 (2003) 425-529
6. Dang L.H., Bettegowda C., Agrawal N., Cheong I., Huso D., Frost P., Loganzo F., Greenberger L., et al. Targeting vascular and avascular compartments of tumors with C. novyi - NT and anti-microtubule agents. Cancer Biol. Therap. 3 (2004) 326-337
7. Darzins A., Nixon L.L., Vangas R.I., and Chakrabarty A.M. Cloning of Escherichia coli and Pseudomonas aeruginosa phosphomannose isomerase genes and their expression in alginate - negative mutants of Pseudomonas aeruginosa. J. Bacteriol. 161 (1985) 249-257
8. Delgado M.A., Poschet J.F., and Deretic V. Nonclassical pathway of Pseudomonas aeruginosa DNA-induced interleukin-8 secretion in cystic fibrosis airway epithelial cells. Infect. Immun. 74 (2006) 2975-2984
9. Droemann D., Albrecht D., Gerdes J., Ulmer A.J., Branscheid D., Vollmer E., Dalhoff K., Zabel P., and Goldmann T. Human lung cancer cells express functionally active Toll-like receptor 9. Respir. Res. 6 (2005) 1-10
10. Feinberg A.P., and Tycko B. The history of cancer epigenetics. Nature Rev. Cancer 4 (2004) 143-153
11. Feng K.K., Zhao H.Y., Qiu H., Liu J.X., and Chen J. Combined therapy with flk1-based DNA vaccine and interleukin-12 results in enhanced antiangiogenic and antitumor effects. Cancer Lett. 221 (2005) 41-47
12. Fialho, A.M., Das Gupta, T.K., Chakrabarty, A.M., in press. Designing promiscuous drugs? Look at what nature made! Lett. Drug Design Discov.
13. Fu G.-F., Li X., Hou Y.-Y., Fan Y.-R., Liu W.-H., and Xu G.-X. Bifidobacterium longum as an oral delivery system of endostatin for gene therapy on solid liver cancer. Cancer Gene Therap. 12 (2005) 133-140
14. Goto M., Yamada T., Kimbara K., Horner J., Newcomb M., Das Gupta T.K., and Chakrabarty A.M. Induction of apoptosis in macrophages by Pseudomonas aeruginosa azurin: tumour-suppressor protein p53 and reactive oxygen species, but not redox activity, as critical elements in cytotoxicity. Mol. Microbiol. 47 (2003) 549-559
15. Hafner M., Zawatzky R., Hirtreiter C., Buurman W.A., Echtenacher B., Hehlgans T., and Mannel D.N. Antimetastatic effect of CpG DNA mediated by typeI IFN. Cancer Res. 61 (2001) 5523-5528
16. Hamilton H.L., Dominquez N.M., Schwartz K.J., Hackett K.T., and Dillard J.P. Neisseria gonorrhoeae secretes chromosomal DNA via a novel type IV secretion system. Mol. Microbiol. 55 (2005) 1704-1721
17. He J., Baldini R.L., Deziel E., Saucier M., Zhang Q., Liberati N.T., Lee D., Urbach J., Goodman H.M., and Rahme L.G. The broad host range pathogen Pseudomonas aeruginosa strain PA14 carries two pathogenicity islands harboring plant and animal virulence genes. Proc. Natl. Acad. Sci. USA 101 (2004) 2530-2535
18. Herman J.G., and Baylin S.B. Gene silencing in cancer in association with promoter hypermethylation. New Engl. J. Med. 349 (2003) 2042-2054
19. Hong C.S., Yamada T., Hashimoto W., Fialho A.M., Das Gupta T.K., and Chakrabarty A.M. Disrupting the entry barrier and attacking brain tumors: the role of the Neisseria H.8 epitope and the Laz protein. Cell Cycle 5 (2006) 1633-1641
20. Hopkins A.L., Mason J.S., and Overington J.P. Can we rationally design promiscuous drugs?. Curr. Opin. Struct. Biol. 16 (2006) 127-136
21. Ivanova N., Sorokin A., Anderson I., Galleron N., Candelon B., Kapatral V., Bhattacharyya A., Reznik G., Mikhailova N., Lapidus A., Chu L., Mazur M., Goltsman E., Larsen N., D'Souza M., Walunas T., Grechkin Y., Pusch G., Haselkorn R., Fonstein M., Ehrlich D.S.D., Overbeek R., and Kyrpides N. Genome sequence of Bacillus cereus and comparative analysis with Bacillus anthracis. Nature 423 (2003) 87-91
22. Kandimalla E.R., Bhagat L., Li Y., Yu D., Wang D., Cong Y.P., Song S.S., Tang I.X., Sullivan T., and Agrawal S. Immunomodulatory oligonucleotides containing a cytosine-phosphate-2′-deoxy-7-deazaguanosine motif as potent toll-like receptor 9 agonist. Proc. Natl. Acad. Sci. USA 102 (2005) 6925-6930
23. Kay E., Humair B., Denervaud B., Riedel K., Spahr S., Eberl L., Valverde C., and Haas D. Two Gac A-dependent small RNAs modulate the quorum-sensing response in Pseudomonas aeruginosa. J. Bacteriol. 188 (2006) 6026-6033
24. Kiewitz C., Larbig K., Klockgether J., Weinel C., and Tummler B. Monitoring genome evolution ex vivo: reversible chrommosomal integration of a 106 kb plasmid at two tRNA (Lys) gene loci in sequential pseudomonas aeruginosa airway isolates. Microbiology 146 (2000) 2365-2373
25. Klockgether J., Reva O., Larbig K., and Tummler B. Sequence analysis of the mobile genome island pKLC102 of Pseudomonas aeruginosa c. J. Bacteriol. 186 (2004) 518-534
26. Kostakioti M., Newman C.L., Thanassi D.G., and Stathopoulos C. Mechanisms of protein export across the bacterial outer membrane. J. Bacteriol. 187 (2005) 4306-4314
27. Krieg A.M. CpG motifs: the active ingredient in bacterial extracts?. Nature Med. 9 (2003) 831-835
28. Krieg A.M. Antitumor applications of stimulating Toll-like receptor 9 with CpG oligodeoxynucleotides. Curr. Oncol. Rep. 6 (2004) 88-95
29. Kulasekara B.R., Kulasekara H.D., Wolfgang M.C., Stevens L., Frank D.W., and Lory S. Acquisition and evolution of the exoU locus in Pseudomonas aeruginosa. J. Bacteriol. 188 (2006) 4037-4050
30. Kwan T., Liu J., Dubow M., Gros P., and Pelletier J. Comparative genomic analysis of 18 Pseudomonas aeruginosa bacteriophages. J. Bacteriol. 188 (2006) 1184-1187
31. Liang X., Pham X.-Q.T., Olson M.V., and Lory S. Identification of a genomic island present in the majority of pathogenic isolates of Pseudomonas aeruginosa. J. Bacteriol. 183 (2001) 843-853
32. Lee, D.G., Urbach, J.M., Wu, G., Liberati, N.T., Feinbaum, R., Miyata, S., Diggins, L.T., He, J., Saucier, M., Deziel, E., Friedman, L., Li, L., Grills, G., Montgomery, K., Kucherlapati, R., Rahme, L.G., Ausubel, F.M., 2006. Genomic analysis reveals that Pseudomonas aeruginosa virulence is combinatorial. Genome Biol. 7, R90.
33. Luo Y., Zhou H., Mizutani M., Mizutani N., Reisfeld R.A., and Xiang R. Transcription factor Fos-related antigen 1 is an effective target for a breast cancer vaccine. Proc. Natl. Acad. Sci. USA 100 (2003) 8850-8855
34. Minton N.P. Clostridia in cancer therapy. Nature Rev. Microbiol. 1 (2003) 237-243
35. Modlin R.L. A Toll for DNA vaccines. Nature 408 (2000) 659-660
36. Niethammer A.G., Xiang R., Becker J.C., Wodrich H., Pertl U., Karsten G., et al. A DNA vaccine against VEGF receptor 2 prevents effective angiogenesis and inhibits tumor growth. Nature Med. 8 (2002) 1369-1375
37. Ohman D.E., and Chakrabarty A.M. Utilization of human respiratory secretions by mucoid Psuedomonas aeruginosa of cystic fibrosis origin. Infect. Immun. 37 (1982) 662-669
38. Parkhill J., Dougan G., James K.D., Thomson N.R., Pickard D., Wain J., Churcher C., Mungall K.L., Bentley S.D., Holden M.T.G., Sebaihia M., Baker S., Basham D., Brooks K., Chillingworth T., Connerton P., Cronin A., Davis P., Davies R.M., Dowd L., White N., Farrar J., Feltwell T., Hamlin N., Haque A., Hien T.T., Holroyd S., Jagels K., Krogh A., Larsen T.S., Leather S., Moule S., O'Gaora P., Parry C., Quail M., Rutherford K., Simmonds M., Skelton J., Stevens K., Whitehead S., and Barrell B.G. Complete genome sequence of a multiple drug resistant Salmonella enterica serovar Typhi CT18. Nature 413 (2001) 848-852
39. Punj V., Bhattacharyya S., Saint-Dic D., Vasu C., Cunningham E.A., Graves J., Yamada T., Constantinou A., et al. Bacterial cupredoxin azurin as an inducer of apoptosis and regression in human breast cancer. Oncogene 23 (2004) 2367-2378
40. Roth B.L., Shefler D.J., and Kroeze W.K. Magic shotguns versus magic bullets: selectively non-selective drugs for mood disorders and schizophrenia. Nature Rev. Drug Discov. 3 (2004) 353-359
41. Sebaihia M., Preston A., Maskell D.J., Kuzmiak H., Connell T.D., King N.D., Orndorff P.E., Miyamoto D.M., Thomson N.R., Harris D., Goble A., Lord A., Murphy L., Quail M.A., Rutter S., Squares R., Squares S., Woodward J., Parkhill J., and Temple L.M. Comparison of the genome sequence of the poultry pathogen Bordetella avium with those of B. bronchiseptica, B. pertussis, and B. parapertussis reveals extensive diversity in surface structures associated with host interaction. J. Bacteriol. 188 (2006) 6002-6015
42. Schindler U., and Baichwal V.R. Three NF-kappa B binding sites in the human E-selectin gene required for maximal tumor necrosis factor alpha-induced expression. Mol. Cell. Biol. 14 (1994) 5820-5831
43. Smith III A.B., Freeze B.S., LaMarche M.J., Sager J., Kinzler K.W., and Vogelstein B. Discodermolide analogues as the chemical component of combination bacteriolytic therapy. Bioorg. Med. Chem. Lett. 15 (2005) 3623-3626
44. Stover C.K., Pham X.Q., Erwin A.L., Mizoguchi S.D., Warrener P., Hickey M.J., Brinkman F.S., Hufnagle W.O., Kowalik D.J., Lagrou M., Garber R.L., Goltry L., Tolentino E., Westbrock-Wadman S., Yuan Y., Brody L.L., Coulter S.N., Folger K.R., Kas A., Larbig K., Lim R., Smith K., Spencer D., Wong G.K., Wu Z., Paulsen I.T., Reizer J., Saier M.H., Hancock R.E., Lory S., and Olson M.V. Complete genome sequence of Pseudomonas aeruginosa PA01, an opportunistic pathogen. Nature 406 (2000) 959-964
45. Takami H., Nakasone K., Takaki Y., Maeno G., Sasaki R., Masui N., Fuji F., Hirama C., Nakamura Y., Ogasawara N., Kuhara S., and Horikoshi K.V. Complete genome sequence of the alkaliphilic bacterium Bacillus halodurans and genomic sequence comparison with Bacillus subtilis. Nucleic Acids Res. 28 (2006) 4317-4331
46. Thamm D.H., Kurzman H.D., King I., Li Z., Sznol M., Dubielzig R.R., Vail D.M., and MacEwen E.G. Systemic administration of an attenuated, tumor-targeting Salmonella typhimurium to dogs with spontaneous neoplasia: phase I evaluation. Clin. Cancer Res. 11 (2005) 4827-4834
47. Thanassi D.G., Stathopoulos C., Karkal A., and Li H. Protein secretion in the absence of ATP: the autotransporter, two-partner secretion and chaperone/usher pathways of Gram-negative bacteria (Review). Mol. Membr. Biol. 22 (2005) 63-72
48. Tokunaga T., Yamamoto T., and Yamamoto S. How BCG led to the discovery of immunostimulatory DNA. Jpn. J. Infect. Dis. 52 (1999) 1-11
49. Toso J.F., Gill V.J., Hwu P., Marincola F.M., Restifo W.P., Schwartzentruber D.J., Sherry J.M., Topalian S.L., et al. Phase I study of the intravenous administration of attenuated Salmonella typhimurium to patients with metastatic melanoma. J. Clin. Oncol. 20 (2002) 142-152
50. van der Meer J.R., Ravatn R., and Sentchilo V. The clc element of Pseudomonas sp. strain B13 and other mobile degradative elements employing phage-like integrases. Arch. Microbiol. 175 (2001) 79-85
51. Vassaux G., Nitcheu J., Jezzard S., and Lemoine N.R. Bacterial gene therapy strategies. J. Pathol. 208 (2006) 290-298
52. Vicente M., Hodgson J., Massidda O., Tonjum T., Henriques-Normark B., and Ron E.Z. The fallacies of hope: will we discover new antibiotics to combat pathogenic bacteria in time?. FEMS Microbiol. Rev. 30 (2006) 841-852
53. Wang W., Huper G., Guo Y., Murphy S.K., Olson J.A., and Marks J.R. Analysis of methylation - sensitive transciptome identifies GADD45a as a frequently methylated gene in breast cancer. Oncogene 24 16 (2005) 2705-2714
54. Whitchurch C.B., Tolker-Nielsen T., Ragas P.C., and Mattick J.S. Extracellular DNA required for bacterial biofilm formation. Science 295 (2002) 1487
55. Woods D.E., Sokol P.A., Bryan L.E., Storey D.G., Mattingly S.J., Vogel H.J., and Ceri H. In vivo regulation of virulence in Pseudomonas aeruginosa associated with genetic rearrangement. J. Infect. Dis. 163 (1991) 143-149
56. Yamada T., Goto M., Punj V., Zaborina O., Chen M.L., Kimbara K., Majumdar D., Cunningham E., Das Gupta T.K., and Chakrabarty A.M. Bacterial redox protein azurin, tumor suppressor protein p53, and regression of cancer. Proc. Natl. Acad. Sci. USA 99 (2002) 14098-14103
57. Yamada T., Fialho A.M., Punj V., Bratescu L., Das Gupta T.K., and Chakrabarty A.M. Internalization of bacterial redox protein azurin in mammalian cells: entry domain and specificity. Cell. Microbiol. 7 (2005) 1418-1431
58. Zaborina O., Dhiman N., Chen M.L., Kostal J., Holder I.A., and Chakrabarty A.M. Secreted products of a non-mucoid Pseudomonas aeruginosa strain induce two modes of macrophage killing: external-ATP-dependent, P2Z-receptor-mediated necrosis and ATP-independent, caspase-mediated apoptosis. Microbiology 146 (2000) 2521-2530