Determination of BAPTA-AM, the acetoxymethyl tetraester of BAPTA, in rat plasma by liquid chromatography tandem mass spectrometry

Journal of Mass Spectrometry

Volumn 41, Issue 12, 2006, Pages 1615-1622

  Zheng, Feng ^a   Hang, Taijun ^a   Wu, Chunyong ^a   Di, Bin ^a   Liu, Wenyin ^a   Xu, Jihua ^a   Zhai, Chunxiao ^a   Sun, Di ^a   Liu, Jinxing ^b   Wei, Wei ^b  

^a CHINA PHARMACEUTICAL UNIVERSITY   (China)

^b Hefei Healstar Medicine Research Institute   (China)

Author keywords

BAPTA AM; Ester; LC ESI MS MS; Rat plasma; Sodium adduct ion

Indexed keywords

BAPTA-AM; ELECTROSPRAY IONIZATION (ESI); RAT PLASMA; SODIUM ADDUCT IONS;

ACETONITRILE; BODY FLUIDS; CALCIUM COMPOUNDS; ENZYME KINETICS; HYDROCHLORIC ACID; HYDROLYSIS; LIQUID CHROMATOGRAPHY; MASS SPECTROMETRY; ORGANIC SOLVENTS; PHARMACOKINETICS; PROTEINS; SODIUM;

ESTERS;

ACETIC ACID; ACETONITRILE; ACETOXYMETHYL TETRAESTER; ESTER DERIVATIVE; ETHYLENE GLYCOL 1,2 BIS(2 AMINOPHENYL) ETHER N,N,N',N' TETRAACETIC ACID; ETHYLENE GLYCOL 1,2 BIS(2 AMINOPHENYL) ETHER N,N,N',N' TETRAACETIC ACID ACETOXYMETHYLESTER; FLUORIDE; FORMIC ACID; HYDROCHLORIC ACID; ORGANIC SOLVENT; SODIUM ION; UNCLASSIFIED DRUG;

ANIMAL EXPERIMENT; CHEMICAL BOND; CONFERENCE PAPER; CONTROLLED STUDY; HYDROLYSIS; LIQUID CHROMATOGRAPHY; NONHUMAN; PRIORITY JOURNAL; RAT; REPRODUCIBILITY; SOLVOLYSIS; STRUCTURE ANALYSIS; TANDEM MASS SPECTROMETRY; VALIDATION PROCESS;

ANIMALS; CALIBRATION; CHELATING AGENTS; CHROMATOGRAPHY, LIQUID; EGTAZIC ACID; NIMODIPINE; RATS; RATS, SPRAGUE-DAWLEY; REPRODUCIBILITY OF RESULTS; TANDEM MASS SPECTROMETRY;

ANIMALIA;

EID: 33845986754     PISSN: 10765174     EISSN: 10969888     Source Type: Journal    
DOI: 10.1002/jms.1125     Document Type: Conference Paper

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