Role of the intracellular domain of IL-7 receptor in T cell development

Journal of Immunology

Volumn 178, Issue 1, 2007, Pages 228-234

  Jiang, Qiong ^a   Huang, Jiaqiang ^b   Li, Wen Qing ^a   Cavinato, Tiziana ^a   Keller, Jonathan E ^c   Durum, Scott K ^a,d  

^a NATIONAL CANCER INSTITUTE   (United States)

^b JOHNS HOPKINS UNIVERSITY SCHOOL OF MEDICINE   (United States)

^c SAIC FREDERICK INC   (United States)

^d Building 560   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

INTERLEUKIN 4 RECEPTOR; INTERLEUKIN 7; INTERLEUKIN 7 RECEPTOR; INTERLEUKIN 9 RECEPTOR; PROLACTIN RECEPTOR; RETROVIRUS VECTOR; T LYMPHOCYTE RECEPTOR BETA CHAIN;

ANIMAL CELL; ARTICLE; CD4+ T LYMPHOCYTE; CD8+ T LYMPHOCYTE; CELL MATURATION; CELL PROLIFERATION; CELL SURVIVAL; CONTROLLED STUDY; GENE LOCUS; GENE REARRANGEMENT; MOUSE; NONHUMAN; NUCLEOTIDE SEQUENCE; PRIORITY JOURNAL; PROTEIN DOMAIN; RECEPTOR INTRINSIC ACTIVITY; SIGNAL TRANSDUCTION; T LYMPHOCYTE; THYMOCYTE;

EID: 33845963550     PISSN: 00221767     EISSN: None     Source Type: Journal    
DOI: 10.4049/jimmunol.178.1.228     Document Type: Article

References (44)

1. von-Freeden-Jeffry, U., P. Vieira, L. A. Lucian, T. McNeil, S. E. Burdach, and R. Murray. 1995. Lymphopenia in interleukin (IL)-7 gene-deleted mice identifies IL-7 as a nonredundant cytokine. J. Exp. Med. 181: 1519-1526.
2. Peschon, J. J., P. J. Morrissey, K. H. Grabstein, F. J. Ramsdell, E. Maraskovsky, B. C. Gliniak, L. S. Park, S. F. Ziegler, D. E. Williams, C. B. Ware, et al. 1994. Early lymphocyte expansion is severely impaired in interleukin 7 receptor-deficient mice. J. Exp. Med. 180: 1955-1960.
3. + severe combined immunodeficiency. Nat. Genet. 20: 394-397.
4. Kim, K., C. K. Lee, T. J. Sayers, K. Muegge, and S. K. Durum. 1998. The trophic action of IL-7 on pro-T cells: inhibition of apoptosis of pro-T1, -T2, and -T3 cells correlates with Bcl-2 and Bax levels and is independent of Fas and p53 pathways. J. Immunol. 160: 5735-5741.
5. Opferman, J, T., A. Letai, C. Beard, M. D. Sorcinelli, C. C. Ong, and S. J. Korsmeyer. 2003. Development and maintenance of B and T lymphocytes requires antiapoptotic MCL-1. Nature 426: 671-676.
6. Akashi, K., M. Kondo, U. von Freeden-Jeffry, R. Murray, and I. L. Weissman. 1997. Bcl-2 rescues T lymphopoiesis in interleukin-7 receptor-deficient mice. Cell 89: 1033-1041.
7. -/- mice. Cell 89: 1011-1019.
8. Khaled, A. R., W. Q. Li, J. Huang, T. J. Fry, A. S. Khaled, C. L. Mackall, K. Muegge, H. A. Young, and S. K. Durum. 2002. Bax deficiency partially corrects interleukin-7 receptor α deficiency. Immunity 17: 561-573.
9. Pellegrini, M., P. Bouillet, M. Robati, G. T. Belz, G. M. Davey, and A. Strasser. 2004. Loss of Bim increases T cell production and function in interleukin 7 receptor-deficient mice. J. Exp. Med. 200: 1189-1195.
10. Durum, S. K., S. Candeias, H. Nakajima, W. J. Leonard, A. M. Baird, L. J. Berg, and K. Muegge. 1998. Interleukin 7 receptor control of T cell receptor γ gene rearrangement: role of receptor-associated chains and locus accessibility. J. Exp. Med. 188: 2233-2241.
11. + T cells. Immunity 13: 59-71.
12. + cell memory: the enigma of Th1 cells. Trends Mol. Med. 9: 186-188.
13. Schluns, K. S., W. C. Kieper, S. C. Jameson, and L. Lefrancois. 2000. Interleukin-7 mediates the homeostasis of naive and memory CD8 T cells in vivo. Nat. Immunol. 1: 426-432.
14. Tan, J. T., E. Dudl, E. LeRoy, R. Murray, J. Sprent, K. I. Weinberg, and C. D. Surh. 2001. IL-7 is critical for homeostatic proliferation and survival of naive T cells. Proc. Natl. Acad. Sci. USA 98: 8732-8737.
15. Khaled, A. R., D. V. Bulavin, C. Kittipatarin, W. Q. Li, M. Alvarez, K. Kim, H. A. Young, A. J. Fornace, and S. K. Durum. 2005. Cytokine-driven proliferation is mediated through Cdc25a. J. Cell Biol. 169: 755-763.
16. Kip1. J. Exp. Med. 203: 573-582.
17. Jiang, Q., W. Q. Li, R. R. Hofmeister, H. A. Young, D. R. Hodge, J. R. Keller, A. R. Khaled, and S. K. Durum. 2004. Distinct regions of the interleukin-7 receptor regulate different Bcl2 family members. Mol. Cell. Biol. 24: 6501-6513.
18. Lin, J. X., T. S. Migone, M. Tsang, M. Friedmann, J. A. Weatherbee, L. Zhou, A. Yamauchi, E. T. Bloom, J. Mietz, S. John, et al. 1995. The role of shared receptor motifs and common Stat proteins in the generation of cytokine pleiotropy and redundancy by IL-2, IL-4, IL-7, IL-13, and IL-15. Immunity 2: 331-339.
19. Venkitaraman, A. R., and R. J. Cowling. 1994. Interleukin-7 induces the association of phosphatidylinositol 3-kinase with the α chain of the interleukin-7 receptor. Eur. J. Immunol. 24: 2168-2174.
20. Jiang, Q., W. Q. Li, F. B. Aiello, R. Mazzucchelli, B. Asefa, A. R. Khaled, and S. K. Durum. 2005. Cell biology of IL-7, a key lymphotrophin. Cytokine Growth Factor Rev. 16: 513-533.
21. Pallard, C., A. P. Stegmann, T. van Kleffens, F. Smart, A. Venkitaraman, and H. Spits. 1999. Distinct roles of the phosphatidylinositol 3-kinase and STAT5 pathways in IL-7-mediated development of human thymocyte precursors. Immunity 10: 525-535.
22. Yao, Z., Y. Cui, W. T. Watford, J. H. Bream, K. Yamaoka, B. D. Hissong, D. Li, S. K. Durum, Q. Jiang, A. Bhandoola, et al. 2006. Stat5a/b are essential for normal lymphoid development and differentiation. Proc. Natl. Acad. Sci. USA 103: 1000-1005.
23. -/- mouse. J. Immunol. Methods 274: 177-184.
24. Garman, R. D., P. J. Doherty, and D. H. Raulet. 1986. Diversity, rearrangement, and expression of murine T cell γ genes. Cell 45: 733-742.
25. Van De Wiele, C. J., J. H. Marino, B. W. Murray, S. S. Vo, M. E. Whetsell, and T. K. Teague. 2004. Thymocytes between the β-selection and positive selection checkpoints are nonresponsive to IL-7 as assessed by STAT-5 phosphorylation. J. Immunol. 172: 4235-4244.
26. -/- bone marrow progenitors: correction of lymphoid deficiency and induction of neutrophilia. Gene Ther. 12: 1761-1768.
27. Candeias, S., K, Muegge, and S. K. Durum. 1996. Junctional diversity in signal joints from T cell receptor β and δ loci via terminal deoxynucleotidyl transferase and exonucleolytic activity. J. Exp. Med. 184: 1919-1926.
28. Townsend, J. M., G. P. Fallon, J. D. Matthews, P. Smith, E. H. Jolin, and N. A. McKenzie. 2000. IL-9-deficient mice establish fundamental roles for IL-9 in pulmonary mastocytosis and goblet cell hyperplasia but not T cell development. Immunity 13: 573-583.
29. De Smedt, M., B. Verhasselt, T. Kerre, D. Vanhecke, E. Naessens, G. Leclercq, J. C. Renauld, J. Van Snick, and J. Plum. 2000. Signals from the IL-9 receptor are critical for the early stages of human intrathymic T cell development. J. Immunol. 164: 1761-1767.
30. Renauld, J. C., A. Vink, J. Louahed, and J. Van Snick. 1995. Interleukin-9 is a major anti-apoptotic factor for thymic lymphomas. Blood 85: 1300-1305.
31. Uyttenhove, C., R. J. Simpson, and J. Van Snick. 1988. Functional and structural characterization of P40, a mouse glycoprotein with T-cell growth factor activity. Proc. Natl. Acad. Sci. USA 85: 6934-6938.
32. Vink, A., J. C. Renauld, G. Warmer, and J. Van Snick. 1993. Interleukin-9 stimulates in vitro growth of mouse thymic lymphomas. Eur. J. Immunol. 23: 1134-1138.
33. Renauld, J. C., N. van der Lugt, A. Vink, M. van Roon, C. Godfraind, G. Warnier, H. Merz, A. Feller, A. Berns, and J. Van Snick. 1994. Thymic lymphomas in interleukin 9 transgenic mice. Oncogene 9: 1327-1332.
34. Li, W. Q., Q. Jiang, A. R. Khaled, J. R. Keller, and S. K. Durum. 2004. Interleukin-7 inactivates the pro-apoptotic protein Bad promoting T cell survival. J. Biol. Chem. 279: 29160-29166.
35. kip1. Blood 98: 1524-1531.
36. Demoulin, J. B., E. Van Roost, M. Stevens, B. Groner, and J. C. Renauld. 1999. Distinct roles for STAT1, STAT3, and STAT5 in differentiation gene induction and apoptosis inhibition by interleukin-9. J. Biol. Chem. 274: 25855-25861.
37. Demoulin, J. P., L. Grasso, J. M. Atkins, M. Stevens, J. Louahed, R. C. Levitt, N. C. Nicolaides, and J. C. Renauld. 2000. Role of insulin receptor substrate-2 in interleukin-9-dependent proliferation. FEBS Lett. 482: 200-204.
38. + T cell differentiation. Immunity 18: 475-487.
39. Lejeune, D., J. B. Demoulin, and J. C. Renauld. 2001. Interleukin 9 induces expression of three cytokine signal inhibitors: cytokine-inducible SH2-containing protein, suppressor of cytokine signalling (SOCS)-2 and SOCS-3, but only SOCS-3 overexpression suppresses interleukin 9 signalling. Biochem. J. 353: 109-116.
40. Imbert, V., and P. R. Renauld. 1999. Duration of STAT5 activation influences the response of interleukin-2 receptor α gene to different cytokines. Eur. Cytokine Network 10: 71-78.
41. Yen, C. H., Y. C. Yang, S. K. Ruscetti, R. A. Kirken, R. M. Dai, and C. C. Li. 2000. Involvement of the ubiquitin-proteasome pathway in the degradation of nontyrosine kinase-type cytokine receptors of IL-9, IL-2, and erythropoietin. J. Immunol. 165: 6372-6380.
42. TrCP E3 ubiquitin ligase. Mol. Cell Biol. 24: 4038-4048.
43. Ye, S. K., Y. Agata, H. C. Lee, H. Kurooka, T. Kitamura, A. Shimizu, T. Honjo, and K. Ikuta. 2001. The IL-7 receptor controls the accessibility of the TCRγ locus by Stat5 and histone acetylation. Immunity 15: 813-823.
44. Moriggl, R., V. Sexl, L. Kenner, C. Duntsch, K. Stangl, S. Gingras, A. Hoffmeyer, A. Bauer, R. Piekorz, D. Wang, et al. 2005. Stat5 tetramer formation is associated with leukemogenesis. Cancer Cell 7: 87-99.