Markers of organophosphate exposure in human serum

Journal of Molecular Neuroscience

Volumn 30, Issue 1-2, 2006, Pages 93-94

  Wieseler, Stacy ^a   Schopfer, Lawrence ^a   Lockridge, Oksana ^a  

^a UNIVERSITY OF NEBRASKA MEDICAL CENTER   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

6 N BIOTINYLAMINOHEXYLISOPROPYLPHOSPHOROFLUORIDATE; ALBUMIN; CHOLINESTERASE; ORGANOPHOSPHATE; UNCLASSIFIED DRUG;

CONFERENCE PAPER; EXPOSURE; HUMAN; IN VITRO STUDY; MASS SPECTROMETRY; PROTEIN ANALYSIS; PROTEIN BINDING; PROTEIN BLOOD LEVEL; PROTEIN DEPLETION;

BIOLOGICAL MARKERS; BLOOD PROTEINS; HUMANS; PHOSPHORIC ACID ESTERS;

EID: 33845951083     PISSN: 08958696     EISSN: None     Source Type: Journal    
DOI: 10.1385/JMN:30:1:93     Document Type: Conference Paper

References (5)

1. King T. P. (2005) Separation of proteins by ammonium sulfate gradient solubilization. Biochemistry 11, 367-371.
2. Michael S. E. (1962) The isolation of albumin from blood serum or plasma by means of organic solvents. Biochem. J. 82, 212-218.
3. Peeples E., Schopfer L., Duysen E., Spaulding R., Volker T., Thompson C., and Lockridge O. (2005) Albumin, a new biomarker of organophosphorus toxicant exposure, identified by mass spectrometry. Toxicol. Sci. 82, 303-312.
4. Rosenoer V. M., Oratz M., and Rothschild M. A. (1997) Albumin Structure, Function, and Uses, Pergamon Press, Oxford, UK, p. 19.
5. Van Der Schans M. J., Polhuijs M., Van Dijk C., Degenhardt C. E., Pleijsier K., Langenberg J. P., and Benschop H. P. (2004) Retrospective detection of exposure to nerve agent: analysis of phosphofluoridate origination from fluoride-induced reactivation of phosphylated BuChE. Arch. Toxicol. 78, 508-524.