Photoproducts and proposed degradation pathway in the riboflavin-sensitised photooxidation of isoproterenol

Pharmazie

Volumn 61, Issue 12, 2006, Pages 1019-1021

  Massad, Walter A ^a   Marioli, J M ^a   Garcia, Norman A ^a  

^a DEPARTAMENTO DE QUÍMICA   (Argentina)

Author keywords

[No Author keywords available]

Indexed keywords

CHROMIUM DERIVATIVE; ISOPRENALINE; N ISOPROPYLAMINOCHROME; RIBOFLAVIN; SUPEROXIDE; UNCLASSIFIED DRUG;

ARTICLE; DEGRADATION KINETICS; DRUG DEGRADATION; DRUG OXIDATION; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; PHOTODEGRADATION; PHOTOOXIDATION; QUANTUM YIELD; SPECTROMETRY;

ADRENERGIC BETA-AGONISTS; ALGORITHMS; CHROMATOGRAPHY, HIGH PRESSURE LIQUID; ISOPROTERENOL; MAGNETIC RESONANCE SPECTROSCOPY; OXIDATION-REDUCTION; PHOTOCHEMISTRY; PHOTOLYSIS; PHOTOSENSITIZING AGENTS; RIBOFLAVIN; SPECTROPHOTOMETRY, ULTRAVIOLET;

EID: 33845945262     PISSN: 00317144     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (18)

1. Ahmad I, Fasihullah Q, Noor A, Ansari IA, Ali QNM (2004) Photolysis of riboflavin in aqueous solution: a kinetic study. Int J Pharm 280: 199-208.
2. Albini A, Fasani E (1998) Drugs: Photochemistry and Photostability. The Royal Society of Chemistry, Cambridge.
3. Chacon JN, McLearie J, Sinclair RS (1988) Singlet oxygen yields and radical contributions in the dye-sensitised photo-oxidation in methanol of esters of polyunsatured fatty acids (oleic, linoleic, linolenic and arachidonic). Photochem Photobiol 47: 647-656.
4. Edwards AM, Silva E (2001) Effect of visible light on selected enzymes, vitamins and amino acids. J Photochem Photobiol B: Biol 63: 126-131.
5. Heelis PF (1982) The photophysical and photochemical properties of flavins (isoalloxazines). Chem Soc Rev 11: 15-39.
6. Holzer W, Shirdel J, Zirak P, Penzkofer A, Hegemann P, Deutzmann R, Hochmuth E (2005) Photo-induced degradation of some flavins in aqueous solution. Chem Phys 308: 69-78.
7. Jahnke LS, Frenkel AW (1978) Photooxidation of epinephrine sensitized by methylene blue-evidence for the involvement of singlet oxygen and of superoxide. Photochem Photobiol 28: 517-523.
8. Kanofsky JR (1991) Singlet oxygen production from the reactions of superoxide ion in aprotic solvents: implications for hydrophobic biochemistry. Free Rad Res Comms 12-13: 87-92.
9. Krishna CM, Uppuluri S, Riesz P, Zigler JS, Balasubramanian D (1991) A study of the photodynamic efficiencies of some eye lens constituents. Photochem Photobiol 54: 51-58.
10. Kruk I (1985) The identification by electron spin resonance spectroscopy of singlet oxygen formed in the photooxidation of catecholamines. Z Phys Chemie (Leipzig) 266: 1239-1242.
11. Litter M (1988) Farmacología experimental y clínica, 7th Ed. edn. El Ateneo, Buenos Aires.
12. Massad WA, Bertolotti S, García NA (2004) Kinetics and Mechanism of the Vitamin B2-sensitized Photooxidation of Isoproterenol. Photochem Photobiol 79: 428-433.
13. Mol NJD, Beijersbergen Van Henegouwen GMJ, Gerritsma KW (1979) Photochemical decomposition of catecholamines-II. The extent of aminochrome formation from adrenaline, isoprenaline and noradrenaline induced by ultraviolet light. Photochem Photobiol 29: 479-482.
14. Pajares A, Gianotti J, Stettler G, Bertolotti S, Criado S, Posadaz A, Amat Guerri F, Garcia NA (2001) Modelling the natural photodegradation of water contaminants - A kinetic study on the light-induced aerobic interactions between riboflavin and 4-hydroxypyridine. J Photochem Photobiol A: Chem 139: 199-204.
15. Posadaz A, Sánchez E, Gutiérrez MI, Calderón M, Bertolotti S, Biasutti MA, García NA (2000) Riboflavin and rose bengal sensitized photooxidation of sulfathiazole and succinylsulfathiazole. Kinetic study and microbiologiacal implications. Dyes Pigm 45: 219-228.
16. Snyder LR, Kirkland JJ, Glajch JL (1997) Practical HPLC method development. J. Wiley & Sons, Inc., New York.
17. Straight RC, Spikes JD (1985) Photosensitised oxidation of biomolecules. In: Frimer AA (ed) Singlet Oxygen. CRC Press, Boca Raton, pp 91-143.
18. Tonnesen HH, Moore DE (1991) Photochemical stability of biologically active compounds. III. Mefloquine as a photosensitizer. Int J Pharm 70: 95-101.