-
1
-
-
0036367094
-
Rational design of stable lyophilized protein formulations: theory and practice
-
Carpenter John F., and Manning Mark C. (Eds), Kluwer, Academic/Plenum Press, New York
-
Carpenter J.F., Chang B.S., Garzon-Rodriguez W., and Randolph T.W. Rational design of stable lyophilized protein formulations: theory and practice. In: Carpenter John F., and Manning Mark C. (Eds). Pharmaceutical Biotechnology. 13. Rational Design of Stable Protein Formulations (2002), Kluwer, Academic/Plenum Press, New York 109-133
-
(2002)
Pharmaceutical Biotechnology. 13. Rational Design of Stable Protein Formulations
, pp. 109-133
-
-
Carpenter, J.F.1
Chang, B.S.2
Garzon-Rodriguez, W.3
Randolph, T.W.4
-
3
-
-
0034255393
-
Lyophilization and development of solid protein pharmaceuticals
-
Wang W. Lyophilization and development of solid protein pharmaceuticals. Int. J. Pharm. 203 (2000) 1-60
-
(2000)
Int. J. Pharm.
, vol.203
, pp. 1-60
-
-
Wang, W.1
-
4
-
-
0036843324
-
Effects of drying methods and additives on the structure, function, and storage stability of subtilisin: role of protein conformation and molecular mobility
-
DePaz R.A., Dale D.A., Barnett C.C., Carpenter J.F., Gaertner A.L., and Randolph T.W. Effects of drying methods and additives on the structure, function, and storage stability of subtilisin: role of protein conformation and molecular mobility. Enzyme Microb. Technol. 31 (2002) 765-774
-
(2002)
Enzyme Microb. Technol.
, vol.31
, pp. 765-774
-
-
DePaz, R.A.1
Dale, D.A.2
Barnett, C.C.3
Carpenter, J.F.4
Gaertner, A.L.5
Randolph, T.W.6
-
5
-
-
28244432903
-
Spray freeze-drying of biopharmaceuticals: applications and stability considerations
-
Costantino H.R., and Pikal M.J. (Eds), American Association of Pharmaceutical Scientists, Arlington
-
Maa Y.-F., and Costantino H.R. Spray freeze-drying of biopharmaceuticals: applications and stability considerations. In: Costantino H.R., and Pikal M.J. (Eds). Biotechnology: Pharmaceutical Aspects. 2. Lyophilization of Biopharmaceuticals (2004), American Association of Pharmaceutical Scientists, Arlington 519-561
-
(2004)
Biotechnology: Pharmaceutical Aspects. 2. Lyophilization of Biopharmaceuticals
, pp. 519-561
-
-
Maa, Y.-F.1
Costantino, H.R.2
-
6
-
-
85056927426
-
Mechanisms of protein stabilization during freeze-drying and storage: the relative importance of thermodynamic stabilization and glassy state relaxation dynamics
-
Pikal M.J. Mechanisms of protein stabilization during freeze-drying and storage: the relative importance of thermodynamic stabilization and glassy state relaxation dynamics. Drugs Pharm. Sci. 137 (2004) 63-107
-
(2004)
Drugs Pharm. Sci.
, vol.137
, pp. 63-107
-
-
Pikal, M.J.1
-
7
-
-
0037308432
-
Stabilization of alum-adjuvanted vaccine dry powder formulations: mechanism and application
-
Maa Y.-F., Zhao L., Payne L.G., and Chen D. Stabilization of alum-adjuvanted vaccine dry powder formulations: mechanism and application. J. Pharm. Sci. 92 (2003) 319-332
-
(2003)
J. Pharm. Sci.
, vol.92
, pp. 319-332
-
-
Maa, Y.-F.1
Zhao, L.2
Payne, L.G.3
Chen, D.4
-
8
-
-
0034601108
-
Sustained release of recombinant human insulin-like growth factor-I for treatment of diabetes
-
Lam X.M., Duenas E.T., Daugherty A.L., Levin N., and Cleland J.L. Sustained release of recombinant human insulin-like growth factor-I for treatment of diabetes. J. Controll. Release 67 (2000) 281-292
-
(2000)
J. Controll. Release
, vol.67
, pp. 281-292
-
-
Lam, X.M.1
Duenas, E.T.2
Daugherty, A.L.3
Levin, N.4
Cleland, J.L.5
-
9
-
-
12244253744
-
Uniform encapsulation of stable protein nanoparticles produced by spray freezing for the reduction of burst release
-
Leach W.T., Simpson D.T., Val T.N., Anuta E.C., Yu Z., Williams III R.O., and Johnston K.P. Uniform encapsulation of stable protein nanoparticles produced by spray freezing for the reduction of burst release. J. Pharm. Sci. 94 (2005) 56-69
-
(2005)
J. Pharm. Sci.
, vol.94
, pp. 56-69
-
-
Leach, W.T.1
Simpson, D.T.2
Val, T.N.3
Anuta, E.C.4
Yu, Z.5
Williams III, R.O.6
Johnston, K.P.7
-
10
-
-
8544246437
-
The stabilization and encapsulation of human growth hormone into biodegradable microspheres
-
Johnson O.L., Jaworowicz W., Cleland J.L., Bailey L., Charnis M., Duenas E., Wu C., Shepard D., Magil S., Last T., Jones A.J.S., and Putney S.D. The stabilization and encapsulation of human growth hormone into biodegradable microspheres. Pharm. Res. 14 (1997) 730-735
-
(1997)
Pharm. Res.
, vol.14
, pp. 730-735
-
-
Johnson, O.L.1
Jaworowicz, W.2
Cleland, J.L.3
Bailey, L.4
Charnis, M.5
Duenas, E.6
Wu, C.7
Shepard, D.8
Magil, S.9
Last, T.10
Jones, A.J.S.11
Putney, S.D.12
-
11
-
-
0034837639
-
Encapsulation and stabilization of nerve growth factor into poly(lactic-co-glycolic) acid microspheres
-
Lam X.M., Duenas E.T., and Cleland J.L. Encapsulation and stabilization of nerve growth factor into poly(lactic-co-glycolic) acid microspheres. J. Pharm. Sci. 90 (2001) 1356-1365
-
(2001)
J. Pharm. Sci.
, vol.90
, pp. 1356-1365
-
-
Lam, X.M.1
Duenas, E.T.2
Cleland, J.L.3
-
12
-
-
1542358759
-
Microneedles for transdermal drug delivery
-
Prausnitz M.R. Microneedles for transdermal drug delivery. Adv. Drug Deliv. Rev. 56 (2004) 581-587
-
(2004)
Adv. Drug Deliv. Rev.
, vol.56
, pp. 581-587
-
-
Prausnitz, M.R.1
-
13
-
-
10744227569
-
Large porous particles for pulmonary drug delivery
-
Edwards D.A., Hanes J., Caponetti G., Hrkach J., Ben-Jebria A., Eskew M.L., Mintzes J., Deaver D., Lotan N., and Langer R. Large porous particles for pulmonary drug delivery. Science 276 (1997) 1868-1871
-
(1997)
Science
, vol.276
, pp. 1868-1871
-
-
Edwards, D.A.1
Hanes, J.2
Caponetti, G.3
Hrkach, J.4
Ben-Jebria, A.5
Eskew, M.L.6
Mintzes, J.7
Deaver, D.8
Lotan, N.9
Langer, R.10
-
14
-
-
2642550862
-
Challenges in the development of high protein concentration formulations
-
Shire S.J., Shahrokh Z., and Liu J. Challenges in the development of high protein concentration formulations. J. Pharm. Sci. 93 (2004) 1390-1402
-
(2004)
J. Pharm. Sci.
, vol.93
, pp. 1390-1402
-
-
Shire, S.J.1
Shahrokh, Z.2
Liu, J.3
-
15
-
-
4844221183
-
Relationship between encapsulated drug particle size and initial release of recombinant human growth hormone from biodegradable microspheres
-
Costantino H.R., Johnson O.L., and Zale S.E. Relationship between encapsulated drug particle size and initial release of recombinant human growth hormone from biodegradable microspheres. J. Pharm. Sci. 93 (2004) 2624-2634
-
(2004)
J. Pharm. Sci.
, vol.93
, pp. 2624-2634
-
-
Costantino, H.R.1
Johnson, O.L.2
Zale, S.E.3
-
16
-
-
0035858370
-
Development of poly-(d,l-lactide-co-glycolide) microsphere formulations containing recombinant human vascular endothelial growth factor to promote local angiogenesis
-
Cleland J.L., Duenas E.T., Park A., Daugherty A., Kahn J., Kowalski J., and Cuthbertson A. Development of poly-(d,l-lactide-co-glycolide) microsphere formulations containing recombinant human vascular endothelial growth factor to promote local angiogenesis. J. Controll. Release 72 (2001) 13-24
-
(2001)
J. Controll. Release
, vol.72
, pp. 13-24
-
-
Cleland, J.L.1
Duenas, E.T.2
Park, A.3
Daugherty, A.4
Kahn, J.5
Kowalski, J.6
Cuthbertson, A.7
-
17
-
-
33645516939
-
Encapsulation of protein nanoparticles into uniform-sized microspheres formed in a spinning oil film
-
Leach W.T., Simpson D.T., Val T.N., Yu Z., Lim K.T., Park E.J., Williams III R.O., and Johnston K.P. Encapsulation of protein nanoparticles into uniform-sized microspheres formed in a spinning oil film. AAPS Pharm. Sci. Tech. 6 (2005) 605-617
-
(2005)
AAPS Pharm. Sci. Tech.
, vol.6
, pp. 605-617
-
-
Leach, W.T.1
Simpson, D.T.2
Val, T.N.3
Yu, Z.4
Lim, K.T.5
Park, E.J.6
Williams III, R.O.7
Johnston, K.P.8
-
18
-
-
0034495318
-
Protein spray-freeze drying. Effect of atomization conditions on particle size and stability
-
Costantino H.R., Firouzabadian L., Hogeland K., Wu C.C., Beganski C., Carrasquillo K.G., Cordova M., Griebenow K., Zale S.E., and Tracy M.A. Protein spray-freeze drying. Effect of atomization conditions on particle size and stability. Pharm. Res. 17 (2000) 1374-1383
-
(2000)
Pharm. Res.
, vol.17
, pp. 1374-1383
-
-
Costantino, H.R.1
Firouzabadian, L.2
Hogeland, K.3
Wu, C.C.4
Beganski, C.5
Carrasquillo, K.G.6
Cordova, M.7
Griebenow, K.8
Zale, S.E.9
Tracy, M.A.10
-
19
-
-
0036281804
-
Surface adsorption of recombinant human interferon-γ in lyophilized and spray-lyophilized formulations
-
Webb S.D., Golledge S.L., Cleland J.L., Carpenter J.F., and Randolph T.W. Surface adsorption of recombinant human interferon-γ in lyophilized and spray-lyophilized formulations. J. Pharm. Sci. 91 (2002) 1474-1487
-
(2002)
J. Pharm. Sci.
, vol.91
, pp. 1474-1487
-
-
Webb, S.D.1
Golledge, S.L.2
Cleland, J.L.3
Carpenter, J.F.4
Randolph, T.W.5
-
20
-
-
0034331056
-
Biopharmaceutical powders: particle formation and formulation considerations
-
Maa Y.-F., and Prestrelski S.J. Biopharmaceutical powders: particle formation and formulation considerations. Curr. Pharm. Biotechnol. 1 (2000) 283-302
-
(2000)
Curr. Pharm. Biotechnol.
, vol.1
, pp. 283-302
-
-
Maa, Y.-F.1
Prestrelski, S.J.2
-
21
-
-
1542615793
-
Protein powders for encapsulation: a comparison of spray-freeze drying and spray drying of darbepoetin alfa
-
Nguyen X.C., Herberger J.D., and Burke P.A. Protein powders for encapsulation: a comparison of spray-freeze drying and spray drying of darbepoetin alfa. Pharm. Res. 21 (2004) 507-514
-
(2004)
Pharm. Res.
, vol.21
, pp. 507-514
-
-
Nguyen, X.C.1
Herberger, J.D.2
Burke, P.A.3
-
22
-
-
0033043629
-
Protein inhalation powders: spray drying vs spray freeze drying
-
Maa Y.-F., Nguyen P.-A., Sweeney T., Shire S.J., and Hsu C.C. Protein inhalation powders: spray drying vs spray freeze drying. Pharm. Res. 16 (1999) 249-254
-
(1999)
Pharm. Res.
, vol.16
, pp. 249-254
-
-
Maa, Y.-F.1
Nguyen, P.-A.2
Sweeney, T.3
Shire, S.J.4
Hsu, C.C.5
-
23
-
-
0033047323
-
Stability and surface activity of lactate dehydrogenase in spray-dried trehalose
-
Adler M., and Lee G. Stability and surface activity of lactate dehydrogenase in spray-dried trehalose. J. Pharm. Sci. 88 (1999) 199-208
-
(1999)
J. Pharm. Sci.
, vol.88
, pp. 199-208
-
-
Adler, M.1
Lee, G.2
-
24
-
-
0034988423
-
Dry powders of stable protein formulations from aqueous solutions prepared using supercritical CO(2)-assisted aerosolization
-
Sellers S.P., Clark G.S., Sievers R.E., and Carpenter J.F. Dry powders of stable protein formulations from aqueous solutions prepared using supercritical CO(2)-assisted aerosolization. J. Pharm. Sci. 90 (2001) 785-797
-
(2001)
J. Pharm. Sci.
, vol.90
, pp. 785-797
-
-
Sellers, S.P.1
Clark, G.S.2
Sievers, R.E.3
Carpenter, J.F.4
-
25
-
-
1842865504
-
Preparation and characterization of microparticles containing peptide produced by a novel process: spray freezing into liquid
-
Yu Z., Rogers T.L., Hu J., Johnston K.P., and Williams III R.O. Preparation and characterization of microparticles containing peptide produced by a novel process: spray freezing into liquid. Eur. J. Pharm. Biopharm. 54 (2002) 221-228
-
(2002)
Eur. J. Pharm. Biopharm.
, vol.54
, pp. 221-228
-
-
Yu, Z.1
Rogers, T.L.2
Hu, J.3
Johnston, K.P.4
Williams III, R.O.5
-
26
-
-
28444436280
-
Spray freezing into liquid versus spray-freeze drying: Influence of atomization on protein aggregation and biological activity
-
Yu Z., Johnston K.P., and Williams III R.O. Spray freezing into liquid versus spray-freeze drying: Influence of atomization on protein aggregation and biological activity. Eur. J. Pharm. Sci. 27 (2006) 9-18
-
(2006)
Eur. J. Pharm. Sci.
, vol.27
, pp. 9-18
-
-
Yu, Z.1
Johnston, K.P.2
Williams III, R.O.3
-
27
-
-
4644223391
-
Spray freezing into liquid nitrogen for highly stable protein nanostructured microparticles
-
Yu Z., Garcia A.S., Johnston K.P., and Williams III R.O. Spray freezing into liquid nitrogen for highly stable protein nanostructured microparticles. Eur. J. Pharm. Biopharm. 58 (2004) 529-537
-
(2004)
Eur. J. Pharm. Biopharm.
, vol.58
, pp. 529-537
-
-
Yu, Z.1
Garcia, A.S.2
Johnston, K.P.3
Williams III, R.O.4
-
28
-
-
0033586786
-
Protein formulation and lyophilization cycle design: prevention of damage due to freeze-concentration induced phase separation
-
Heller M.C., Carpenter J.F., and Randolph T.W. Protein formulation and lyophilization cycle design: prevention of damage due to freeze-concentration induced phase separation. Biotechnol. Bioeng. 63 (1999) 166-174
-
(1999)
Biotechnol. Bioeng.
, vol.63
, pp. 166-174
-
-
Heller, M.C.1
Carpenter, J.F.2
Randolph, T.W.3
-
29
-
-
2342627492
-
Formulation development of protein dosage forms
-
Nail S.L., and Akers M.J. (Eds), Kluwer, Academic/Plenum Press, New York
-
Akers M.J., Vasudevan V., and Stickelmeyer M. Formulation development of protein dosage forms. In: Nail S.L., and Akers M.J. (Eds). Pharmaceutical Biotechnology. 14. Development and Manufacture of Protein Pharmaceuticals (2002), Kluwer, Academic/Plenum Press, New York 47-127
-
(2002)
Pharmaceutical Biotechnology. 14. Development and Manufacture of Protein Pharmaceuticals
, pp. 47-127
-
-
Akers, M.J.1
Vasudevan, V.2
Stickelmeyer, M.3
-
30
-
-
4644320684
-
Simultaneous determination of structural and thermodynamic effects of carbohydrate solutes on the thermal stability of ribonuclease A
-
O'Connor T.F., Debenedetti P.G., and Carbeck J.D. Simultaneous determination of structural and thermodynamic effects of carbohydrate solutes on the thermal stability of ribonuclease A. J. Am. Chem. Soc. 126 (2004) 11794-11795
-
(2004)
J. Am. Chem. Soc.
, vol.126
, pp. 11794-11795
-
-
O'Connor, T.F.1
Debenedetti, P.G.2
Carbeck, J.D.3
-
31
-
-
0141453955
-
Hyperquenching and cold equilibration strategies for the study of liquid-liquid and protein folding transitions
-
Angell C.A., and Wang L.-M. Hyperquenching and cold equilibration strategies for the study of liquid-liquid and protein folding transitions. Biophys. Chem. 105 (2003) 621-637
-
(2003)
Biophys. Chem.
, vol.105
, pp. 621-637
-
-
Angell, C.A.1
Wang, L.-M.2
-
32
-
-
0032962882
-
The effect of formulation excipients on protein stability and aerosol performance of spray-dried powders of a recombinant humanized anti-IgE monoclonal antibody
-
Andya J.D., Maa Y.-F., Costantino H.R., Nguyen P.-A., Dasovich N., Sweeney T.D., Hsu C.C., and Shire S.J. The effect of formulation excipients on protein stability and aerosol performance of spray-dried powders of a recombinant humanized anti-IgE monoclonal antibody. Pharm. Res. 16 (1999) 350-358
-
(1999)
Pharm. Res.
, vol.16
, pp. 350-358
-
-
Andya, J.D.1
Maa, Y.-F.2
Costantino, H.R.3
Nguyen, P.-A.4
Dasovich, N.5
Sweeney, T.D.6
Hsu, C.C.7
Shire, S.J.8
-
33
-
-
33845940781
-
-
Y.-F. Maa, P.-A. Nguyen, Method of spray freeze drying proteins for pharmaceutical administration, U.S. Patent, 6,284,282, 2001.
-
-
-
-
34
-
-
0036170355
-
Protein spray freeze drying. 2. Effect of formulation variables on particle size and stability
-
Costantino H.R., Firouzabadian L., Wu C.C., Carrasquillo K.G., Griebenow K., Zale S.E., and Tracy M.A. Protein spray freeze drying. 2. Effect of formulation variables on particle size and stability. J. Pharm. Sci. 91 (2002) 388-395
-
(2002)
J. Pharm. Sci.
, vol.91
, pp. 388-395
-
-
Costantino, H.R.1
Firouzabadian, L.2
Wu, C.C.3
Carrasquillo, K.G.4
Griebenow, K.5
Zale, S.E.6
Tracy, M.A.7
-
35
-
-
0026016473
-
Ultra-rapid freezing by spraying/plunging: pre-cooling in the cold gaseous layer
-
Chang Z.H., and Baust J.G. Ultra-rapid freezing by spraying/plunging: pre-cooling in the cold gaseous layer. J. Microsc. 161 (1991) 435-444
-
(1991)
J. Microsc.
, vol.161
, pp. 435-444
-
-
Chang, Z.H.1
Baust, J.G.2
-
36
-
-
0002647051
-
Surface activity and functional properties of proteins
-
Magdassi S. (Ed), Marcel Dekker, New York
-
Magdassi S., and Kamyshny A. Surface activity and functional properties of proteins. In: Magdassi S. (Ed). Surface Activity of Proteins (1996), Marcel Dekker, New York 1-38
-
(1996)
Surface Activity of Proteins
, pp. 1-38
-
-
Magdassi, S.1
Kamyshny, A.2
-
37
-
-
0036746811
-
Improvement of dissolution rates of poorly water soluble APIs using novel spray freezing into liquid technology
-
Hu J., Rogers T.L., Brown J., Young T., Johnston K.P., and Williams III R.O. Improvement of dissolution rates of poorly water soluble APIs using novel spray freezing into liquid technology. Pharm. Res. 19 (2002) 1278-1284
-
(2002)
Pharm. Res.
, vol.19
, pp. 1278-1284
-
-
Hu, J.1
Rogers, T.L.2
Brown, J.3
Young, T.4
Johnston, K.P.5
Williams III, R.O.6
-
38
-
-
1142309798
-
Rapid dissolving high potency danazol powders produced by spray freezing into liquid process
-
Hu J., Johnston K.P., and Williams III R.O. Rapid dissolving high potency danazol powders produced by spray freezing into liquid process. Int. J. Pharm. 271 (2004) 145-154
-
(2004)
Int. J. Pharm.
, vol.271
, pp. 145-154
-
-
Hu, J.1
Johnston, K.P.2
Williams III, R.O.3
-
39
-
-
0037151528
-
A novel particle engineering technology: spray-freezing into liquid
-
Rogers T.L., Hu J., Yu Z., Johnston K.P., and Williams III R.O. A novel particle engineering technology: spray-freezing into liquid. Int. J. Pharm. 242 (2002) 93-100
-
(2002)
Int. J. Pharm.
, vol.242
, pp. 93-100
-
-
Rogers, T.L.1
Hu, J.2
Yu, Z.3
Johnston, K.P.4
Williams III, R.O.5
-
40
-
-
0036849433
-
A novel particle engineering technology to enhance dissolution of poorly water soluble drugs: spray-freezing into liquid
-
Rogers T.L., Nelsen A.C., Hu J., Brown J.N., Sarkari M., Young T.J., Johnston K.P., and Williams III R.O. A novel particle engineering technology to enhance dissolution of poorly water soluble drugs: spray-freezing into liquid. Eur. J. Pharm. Biopharm. 54 (2002) 271-280
-
(2002)
Eur. J. Pharm. Biopharm.
, vol.54
, pp. 271-280
-
-
Rogers, T.L.1
Nelsen, A.C.2
Hu, J.3
Brown, J.N.4
Sarkari, M.5
Young, T.J.6
Johnston, K.P.7
Williams III, R.O.8
-
41
-
-
27244462333
-
Maintenance of quaternary structure in the frozen state stabilizes lactate dehydrogenase during freeze-drying
-
Anchordoquy T.J., Izutsu K.-I., Randolph T.W., and Carpenter J.F. Maintenance of quaternary structure in the frozen state stabilizes lactate dehydrogenase during freeze-drying. Arch. Biochem. Biophys. 390 (2001) 35-41
-
(2001)
Arch. Biochem. Biophys.
, vol.390
, pp. 35-41
-
-
Anchordoquy, T.J.1
Izutsu, K.-I.2
Randolph, T.W.3
Carpenter, J.F.4
-
42
-
-
0030586740
-
Polymers protect lactate dehydrogenase during freeze-drying by inhibiting dissociation in the frozen state
-
Anchordoquy T.J., and Carpenter J.F. Polymers protect lactate dehydrogenase during freeze-drying by inhibiting dissociation in the frozen state. Arch. Biochem. Biophys. 332 (1996) 231-238
-
(1996)
Arch. Biochem. Biophys.
, vol.332
, pp. 231-238
-
-
Anchordoquy, T.J.1
Carpenter, J.F.2
-
43
-
-
33745926621
-
Freezing- and drying-induced perturbations of protein structure and mechanisms of protein protection by stabilizing additives
-
Rey L., and May J.C. (Eds), Marcel Dekker, New York
-
Carpenter J.F., Izutsu K.-i., and Randolph T.W. Freezing- and drying-induced perturbations of protein structure and mechanisms of protein protection by stabilizing additives. In: Rey L., and May J.C. (Eds). Drugs and the Pharmaceutical Sciences. 137. Freeze-Drying/Lyophilization of Pharmaceutical and Biological Products (2004), Marcel Dekker, New York 147-186
-
(2004)
Drugs and the Pharmaceutical Sciences. 137. Freeze-Drying/Lyophilization of Pharmaceutical and Biological Products
, pp. 147-186
-
-
Carpenter, J.F.1
Izutsu, K.-i.2
Randolph, T.W.3
-
44
-
-
33845931682
-
-
C. Sonner, PhD Thesis, University of Erlangen-Nuremburg, 2002.
-
-
-
-
45
-
-
0029822814
-
Tetrameric and octameric lactate dehydrogenase from the hyperthermophilic bacterium thermotoga maritima: structure and stability of the two active forms
-
Dams T., Ostendorp R., Ott M., Rutkat K., and Jaenicke R. Tetrameric and octameric lactate dehydrogenase from the hyperthermophilic bacterium thermotoga maritima: structure and stability of the two active forms. Eur. J. Biochem. 240 (1996) 274-279
-
(1996)
Eur. J. Biochem.
, vol.240
, pp. 274-279
-
-
Dams, T.1
Ostendorp, R.2
Ott, M.3
Rutkat, K.4
Jaenicke, R.5
-
46
-
-
77956940478
-
Lactate dehydrogenase
-
Boyer P.D. (Ed), Academic Press, New York
-
Holbrook J.J., Liljas A., Steindel S.J., and Rossmann M.G. Lactate dehydrogenase. In: Boyer P.D. (Ed). Enzymes. 3rd ed. (1975), Academic Press, New York 191-292
-
(1975)
Enzymes. 3rd ed.
, pp. 191-292
-
-
Holbrook, J.J.1
Liljas, A.2
Steindel, S.J.3
Rossmann, M.G.4
-
47
-
-
33845916087
-
-
J.D. Engstrom, D.T. Simpson, E. Lai, R.O. Williams III, K.P. Johnston, Morphology of protein particles produced by spray freezing of concentrated, Eur. J. Pharm. Biopharm., in press.
-
-
-
-
49
-
-
0034732337
-
Mechanism governing microparticle morphology during precipitation by a compressed antisolvent: atomization vs. nucleation and growth
-
Lengsfeld C.S., Delplanque J.P., Barocas V.H., and Randolph T.W. Mechanism governing microparticle morphology during precipitation by a compressed antisolvent: atomization vs. nucleation and growth. J. Phys. Chem. B 104 (2000) 2725-2735
-
(2000)
J. Phys. Chem. B
, vol.104
, pp. 2725-2735
-
-
Lengsfeld, C.S.1
Delplanque, J.P.2
Barocas, V.H.3
Randolph, T.W.4
-
50
-
-
0002933416
-
Cryofixation without pretreatment at ambient pressure
-
Steinbrecht R.A., and Zierold K. (Eds), Springer-Verlag, Berlin
-
Sitte H., Edelmann L., and Neumann K. Cryofixation without pretreatment at ambient pressure. In: Steinbrecht R.A., and Zierold K. (Eds). Cryotechniques in Biological Electron Microscopy (1987), Springer-Verlag, Berlin 87-113
-
(1987)
Cryotechniques in Biological Electron Microscopy
, pp. 87-113
-
-
Sitte, H.1
Edelmann, L.2
Neumann, K.3
-
51
-
-
0034833878
-
Lyophilization-induced protein denaturation in phosphate buffer systems: monomeric and tetrameric β-galactosidase
-
Pikal-Cleland K.A., and Carpenter J.F. Lyophilization-induced protein denaturation in phosphate buffer systems: monomeric and tetrameric β-galactosidase. J. Pharm. Sci. 90 (2001) 1255-1268
-
(2001)
J. Pharm. Sci.
, vol.90
, pp. 1255-1268
-
-
Pikal-Cleland, K.A.1
Carpenter, J.F.2
-
53
-
-
0023905575
-
The mechanism of cryoprotection of proteins by solutes
-
Carpenter J.F., and Crowe J.H. The mechanism of cryoprotection of proteins by solutes. Cryobiology 25 (1988) 244-255
-
(1988)
Cryobiology
, vol.25
, pp. 244-255
-
-
Carpenter, J.F.1
Crowe, J.H.2
-
54
-
-
0027310845
-
The control of protein stability and association by weak interactions with water: how do solvents affect these processes?
-
Timasheff S.N. The control of protein stability and association by weak interactions with water: how do solvents affect these processes?. Annu. Rev. Biophys. Biomol. Struct. 22 (1993) 67-97
-
(1993)
Annu. Rev. Biophys. Biomol. Struct.
, vol.22
, pp. 67-97
-
-
Timasheff, S.N.1
-
55
-
-
0030443567
-
Surface-induced denaturation of proteins during freezing and its inhibition by surfactants
-
Chang B.S., Kendrick B.S., and Carpenter J.F. Surface-induced denaturation of proteins during freezing and its inhibition by surfactants. J. Pharm. Sci. 85 (1996) 1325-1330
-
(1996)
J. Pharm. Sci.
, vol.85
, pp. 1325-1330
-
-
Chang, B.S.1
Kendrick, B.S.2
Carpenter, J.F.3
-
56
-
-
0037381974
-
Effects of annealing lyophilized and spray-lyophilized formulations of recombinant human interferon-γ
-
Webb S.D., Cleland J.L., Carpenter J.F., and Randolph T.W. Effects of annealing lyophilized and spray-lyophilized formulations of recombinant human interferon-γ. J. Pharm. Sci. 92 (2003) 715-729
-
(2003)
J. Pharm. Sci.
, vol.92
, pp. 715-729
-
-
Webb, S.D.1
Cleland, J.L.2
Carpenter, J.F.3
Randolph, T.W.4
|