Lead discovery and optimization of T-type calcium channel blockers

Bioorganic and Medicinal Chemistry

Volumn 15, Issue 3, 2007, Pages 1409-1419

  Park, Jung Hwan ^a,b   Choi, Jin Kyu ^a   Lee, Eunjung ^a   Lee, Jae Kyun ^a   Rhim, Hyewhon ^a   Seo, Seon Hee ^a   Kim, Yoonjee ^a   Doddareddy, Munikumar Reddy ^a   Pae, Ae Nim ^a   Kang, Jahyo ^b   Roh, Eun Joo ^a  

^a Korea Institute of Science and Technology   (South Korea)

^b Sogang University   (South Korea)

Author keywords

[No Author keywords available]

Indexed keywords

AMIDE; CALCIUM CHANNEL BLOCKING AGENT; CALCIUM CHANNEL T TYPE; MIBEFRADIL; PIPERAZINE DERIVATIVE;

ARTICLE; CONTROLLED STUDY; DRUG ACTIVITY; DRUG SCREENING; DRUG STRUCTURE; DRUG SYNTHESIS; HUMAN; HUMAN CELL; IC 50; PATCH CLAMP;

ALKANES; AMIDES; ANIMALS; CALCIUM; CALCIUM CHANNEL BLOCKERS; CALCIUM CHANNELS, T-TYPE; CELLS, CULTURED; DRUG DESIGN; INHIBITORY CONCENTRATION 50; KIDNEY; MIBEFRADIL; MODELS, CHEMICAL; MOLECULAR STRUCTURE; OOCYTES; PIPERAZINES; STEREOISOMERISM; STRUCTURE-ACTIVITY RELATIONSHIP; XENOPUS LAEVIS;

EID: 33845935853     PISSN: 09680896     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.bmc.2006.11.004     Document Type: Article

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