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Volumn 12, Issue 1-2, 2006, Pages 153-164

Nigella sativa seed constituents and anxiety relief in experimental models

Author keywords

pinene; Anxiolysis; Benzodiazepine receptors; p cymene; Thymoquinone

Indexed keywords

BENZODIAZEPINE RECEPTOR; BENZODIAZEPINE RECEPTOR BLOCKING AGENT; ESSENTIAL OIL; FLUMAZENIL; LORAZEPAM; NIGELLA SATIVA EXTRACT; PARA CYMENE; PINENE; THYMOQUINONE;

EID: 33845934975     PISSN: 10496475     EISSN: 15403580     Source Type: Journal    
DOI: 10.1300/J044v12n01_14     Document Type: Article
Times cited : (18)

References (40)
  • 1
    • 0034648056 scopus 로고    scopus 로고
    • Antinociceptive effects of Nigella sativa oil and its major component, thymoquinone, in mice
    • Abdel-Fattah, A.M., K. Matsumoto, and H. Watanabe. 2000. Antinociceptive effects of Nigella sativa oil and its major component, thymoquinone, in mice. Eur. J. Pharmacol. 14:400, 89-97.
    • (2000) Eur. J. Pharmacol , vol.14 , Issue.400 , pp. 89-97
    • Abdel-Fattah, A.M.1    Matsumoto, K.2    Watanabe, H.3
  • 2
    • 0028985043 scopus 로고
    • TLC assay of thymoquinone in black seed oil (Nigella sativa) and identification of dithymoquinone and thymol
    • AbouBasha, L.I., M.S. Rashed, and Y. Aboua-Enein. 1995. TLC assay of thymoquinone in black seed oil (Nigella sativa) and identification of dithymoquinone and thymol. J. Liq. Chromatogr. 18:105-115.
    • (1995) J. Liq. Chromatogr , vol.18 , pp. 105-115
    • AbouBasha, L.I.1    Rashed, M.S.2    Aboua-Enein, Y.3
  • 4
    • 0030037348 scopus 로고    scopus 로고
    • Antiulcer effects of aqueous extracts of Nigella sativa and Pongamia pinnata in rats
    • Akhtar, A.M., K.D. Ahmad, S.N. Gilani, and A. Nazir. 1996. Antiulcer effects of aqueous extracts of Nigella sativa and Pongamia pinnata in rats. Fitoterapia. 57:195-1999.
    • (1996) Fitoterapia , vol.57 , pp. 195-1999
    • Akhtar, A.M.1    Ahmad, K.D.2    Gilani, S.N.3    Nazir, A.4
  • 5
    • 0021878237 scopus 로고
    • On the mechanism of the hypoglycemic effect of a plant extract
    • Al-Awadi, F.M., M.A. Mukhtar, K.A. Gumma. 1985. On the mechanism of the hypoglycemic effect of a plant extract. Diabetologia. 28(7):432-434.
    • (1985) Diabetologia , vol.28 , Issue.7 , pp. 432-434
    • Al-Awadi, F.M.1    Mukhtar, M.A.2    Gumma, K.A.3
  • 6
    • 0026782908 scopus 로고
    • Chemical composition and microflora of black cumin (Nigella sativa) seeds growing in Saudi Arabia
    • Al-Jassir, M.S. 1992. Chemical composition and microflora of black cumin (Nigella sativa) seeds growing in Saudi Arabia. Food Chemistry. 45:239-242.
    • (1992) Food Chemistry , vol.45 , pp. 239-242
    • Al-Jassir, M.S.1
  • 8
    • 84983505716 scopus 로고
    • Proximate analysis, fatty acid and amino acid composition of Nigella sativa seeds
    • Babayan, V.K., D. Kootungal, and G.A. Halaby. 1978. Proximate analysis, fatty acid and amino acid composition of Nigella sativa seeds. J. Food Sci. 43:1314-1315.
    • (1978) J. Food Sci , vol.43 , pp. 1314-1315
    • Babayan, V.K.1    Kootungal, D.2    Halaby, G.A.3
  • 9
    • 0003601534 scopus 로고    scopus 로고
    • Budavari, S. ed, 12th Ed. Merck and Co, Inc, Whitehouse Station, NJ
    • Budavari, S. ed 1996. Merck index, 12th Ed. Merck and Co., Inc., Whitehouse Station, NJ.
    • (1996) Merck index
  • 10
    • 0000959715 scopus 로고
    • The pharmacologically active principle in Nigella sativa
    • Canonica, L., G. Jomoni, C. Scolastico, and A. Bonati. 1963. The pharmacologically active principle in Nigella sativa. Gazz. Chem. Ital. 93:1404-1407.
    • (1963) Gazz. Chem. Ital , vol.93 , pp. 1404-1407
    • Canonica, L.1    Jomoni, G.2    Scolastico, C.3    Bonati, A.4
  • 11
    • 0019460389 scopus 로고
    • Chlodiazepoxide selectively potentiates GABA conductance of spinal cord and sensory neurons in cell culture
    • Choi, D.W., D.H. Farb, and G.D. Fischbach. 1981. Chlodiazepoxide selectively potentiates GABA conductance of spinal cord and sensory neurons in cell culture. J Neurophysiol. 45:621-631.
    • (1981) J Neurophysiol , vol.45 , pp. 621-631
    • Choi, D.W.1    Farb, D.H.2    Fischbach, G.D.3
  • 12
    • 0018333884 scopus 로고
    • Molecular mechanisms in the receptor action of benzodiazepines
    • Costa, E. and A. Guidotti. 1979. Molecular mechanisms in the receptor action of benzodiazepines. Ann Rev Pharmacol Toxicol. 19:531-545.
    • (1979) Ann Rev Pharmacol Toxicol , vol.19 , pp. 531-545
    • Costa, E.1    Guidotti, A.2
  • 13
    • 0027078275 scopus 로고
    • The anxiogenic-like effects of pentylenetetrazole in mice treated chronically with carbamazepine or valproate
    • De-Anglis, L. 1992. The anxiogenic-like effects of pentylenetetrazole in mice treated chronically with carbamazepine or valproate. Methods Find. Exp. Clin. Pharmacol. 14:767-771.
    • (1992) Methods Find. Exp. Clin. Pharmacol , vol.14 , pp. 767-771
    • De-Anglis, L.1
  • 14
    • 0029118093 scopus 로고
    • Effects of valproate and lorazepam on experimental anxiety: Tolerence, withdrawal, and role of clonidine
    • De-Anglis, L. 1995. Effects of valproate and lorazepam on experimental anxiety: Tolerence, withdrawal, and role of clonidine. Pharmacol. Biochem. Behav. 52:329-333.
    • (1995) Pharmacol. Biochem. Behav , vol.52 , pp. 329-333
    • De-Anglis, L.1
  • 15
    • 0000736137 scopus 로고
    • High performance liquid chromatographic analysis of the pharmacologically active quinines and related compounds in the oil of the black seeds (Nigella sativa L.)
    • El-Alfy, T.S., H.E. El-Fatatry, and M.A. Toama. 1975. High performance liquid chromatographic analysis of the pharmacologically active quinines and related compounds in the oil of the black seeds (Nigella sativa L.). Pharmazie. 30:109.
    • (1975) Pharmazie , vol.30 , pp. 109
    • El-Alfy, T.S.1    El-Fatatry, H.E.2    Toama, M.A.3
  • 16
    • 0012957623 scopus 로고
    • Studies on the chemical constitution of Egyptian Nigella sativa L. Seeds
    • El-Dakhakhny, M. 1963. Studies on the chemical constitution of Egyptian Nigella sativa L. Seeds. Pharmazie. 30:109-111.
    • (1963) Pharmazie , vol.30 , pp. 109-111
    • El-Dakhakhny, M.1
  • 17
    • 0016431808 scopus 로고
    • Isolation and structure assignment of an antimicrobial principle from the volatile oil of Nigella sativa L. seeds
    • El-Fatary, H.M. 1975. Isolation and structure assignment of an antimicrobial principle from the volatile oil of Nigella sativa L. seeds. Pharmazie. 30(2):109-111.
    • (1975) Pharmazie , vol.30 , Issue.2 , pp. 109-111
    • El-Fatary, H.M.1
  • 18
    • 0037357837 scopus 로고    scopus 로고
    • Evaluation of Nigella sativa constituents for their in vivo toxicity in mice
    • El-Hadiyah, T.M., M. Raza, O.Y. Mohammed, and A.A. Abdallah. 2003. Evaluation of Nigella sativa constituents for their in vivo toxicity in mice. Natural Product Sciences. 9(1):22-27.
    • (2003) Natural Product Sciences , vol.9 , Issue.1 , pp. 22-27
    • El-Hadiyah, T.M.1    Raza, M.2    Mohammed, O.Y.3    Abdallah, A.A.4
  • 19
    • 0035144675 scopus 로고    scopus 로고
    • Prgabalin may represent a novel class of anxiolytic agents with a broad spectrum of activity
    • Field, M.J., R.J. Oles, and L. Singh. 2001. Prgabalin may represent a novel class of anxiolytic agents with a broad spectrum of activity. Br Journ. Pharmacol. 132:1-4.
    • (2001) Br Journ. Pharmacol , vol.132 , pp. 1-4
    • Field, M.J.1    Oles, R.J.2    Singh, L.3
  • 21
    • 0033120349 scopus 로고    scopus 로고
    • High performance liquid chromatographic analysis of the pharmacologically active quinones and related compounds in the oil of the black seed (Nigella sativa L.)
    • Ghosheh, O.A., A.A. Houdi, and P.A. Crooks. 1999. High performance liquid chromatographic analysis of the pharmacologically active quinones and related compounds in the oil of the black seed (Nigella sativa L.). J Pharm Biomed Anal. 19(5):757-762.
    • (1999) J Pharm Biomed Anal , vol.19 , Issue.5 , pp. 757-762
    • Ghosheh, O.A.1    Houdi, A.A.2    Crooks, P.A.3
  • 22
    • 0031854080 scopus 로고    scopus 로고
    • Characterization of the behavioural profile of the non-peptide CRF receptor antagonist CP-154,526 in anxiety models in rodents. Comparison with diazepam and buspirone
    • Griebel, G., G. Perrault, and D.J. Sanger. 1998. Characterization of the behavioural profile of the non-peptide CRF receptor antagonist CP-154,526 in anxiety models in rodents. Comparison with diazepam and buspirone. Psychopharmacology (Berl). 138:55-66.
    • (1998) Psychopharmacology (Berl) , vol.138 , pp. 55-66
    • Griebel, G.1    Perrault, G.2    Sanger, D.J.3
  • 24
    • 33845926532 scopus 로고    scopus 로고
    • Hashim, F.M. and M.A. El-Kiey. 1962. Nigella sativa seeds of Egypt. J. Pharm. Sci. UAR. 3:121-133.
    • Hashim, F.M. and M.A. El-Kiey. 1962. Nigella sativa seeds of Egypt. J. Pharm. Sci. UAR. 3:121-133.
  • 25
    • 0032992748 scopus 로고    scopus 로고
    • Nociceptin/orphanin FQ and nocistatin on learning and memory impairment induced by scopolamine in mice
    • Hiramatsu, M. and K. Inoue. 1999. Nociceptin/orphanin FQ and nocistatin on learning and memory impairment induced by scopolamine in mice. Br. J Pharmacol. 127:655-660.
    • (1999) Br. J Pharmacol , vol.127 , pp. 655-660
    • Hiramatsu, M.1    Inoue, K.2
  • 26
    • 0028852880 scopus 로고
    • Fixed oil of Nigella sativa and derived thymoquinone inhibit eicosanoid generation in leukocytes and membrane lipid peroxidation
    • Houghton, P.J., R. Zaka, P.D. Hera, and J.R.S. Hoult. 1995. Fixed oil of Nigella sativa and derived thymoquinone inhibit eicosanoid generation in leukocytes and membrane lipid peroxidation. Planta Medica. 61:33-36.
    • (1995) Planta Medica , vol.61 , pp. 33-36
    • Houghton, P.J.1    Zaka, R.2    Hera, P.D.3    Hoult, J.R.S.4
  • 28
    • 0027379097 scopus 로고
    • CNS and analgesic studies onNigella sativa
    • Khanna, T, F.A. Zaidi, and P.C. Dandiyn. 1993. CNS and analgesic studies onNigella sativa. Fitoterapia. 64:407-410.
    • (1993) Fitoterapia , vol.64 , pp. 407-410
    • Khanna, T.1    Zaidi, F.A.2    Dandiyn, P.C.3
  • 29
    • 0022565563 scopus 로고
    • Anticonvulsant drugs: Mechanism of action
    • Macdonald, R.L. and M.J. McLean. 1986. Anticonvulsant drugs: Mechanism of action. Adv Neurol. 44:713-735.
    • (1986) Adv Neurol , vol.44 , pp. 713-735
    • Macdonald, R.L.1    McLean, M.J.2
  • 30
    • 0023264353 scopus 로고
    • The benzodiazepines and their receptors: 25 years of progress
    • Martin, I.L. 1987. The benzodiazepines and their receptors: 25 years of progress. Neuropharmacology. 26:957-970.
    • (1987) Neuropharmacology , vol.26 , pp. 957-970
    • Martin, I.L.1
  • 31
    • 0023233153 scopus 로고
    • Flumazenil in the management of acute drug overdose with benzodiazepine and other agents
    • O'Sullivan, G.F. and D.N. Wade. 1987. Flumazenil in the management of acute drug overdose with benzodiazepine and other agents. Clin. Pharmacol. Ther. 42:254-259.
    • (1987) Clin. Pharmacol. Ther , vol.42 , pp. 254-259
    • O'Sullivan, G.F.1    Wade, D.N.2
  • 32
    • 0025347145 scopus 로고
    • The effectiveness of flumazenil in reversing the sedation and amnesia produced by intravenous midazolam
    • Ochs, M.W., M.R. Tucker, T.G. Owsley, and J.A. Anderson. 1990. The effectiveness of flumazenil in reversing the sedation and amnesia produced by intravenous midazolam. J Oral Maxillofac Surg. 48:240-245.
    • (1990) J Oral Maxillofac Surg , vol.48 , pp. 240-245
    • Ochs, M.W.1    Tucker, M.R.2    Owsley, T.G.3    Anderson, J.A.4
  • 33
    • 0019843403 scopus 로고
    • A water-lick conflict paradigm using drug experienced rats
    • Petersen, E.N. and J.B. Lassen. 1981. A water-lick conflict paradigm using drug experienced rats. Psychopharmacology. 75:236-239.
    • (1981) Psychopharmacology , vol.75 , pp. 236-239
    • Petersen, E.N.1    Lassen, J.B.2
  • 35
    • 0023684638 scopus 로고
    • Electrophysiology of benzodiazepine receptor ligands: Multiple mechanisms and site of action
    • Polc, P. 1988. Electrophysiology of benzodiazepine receptor ligands: Multiple mechanisms and site of action. Prog. Neurobiol. 31:349-423.
    • (1988) Prog. Neurobiol , vol.31 , pp. 349-423
    • Polc, P.1
  • 36
    • 0015759122 scopus 로고
    • Sterols in the seed oil of Nigella sativa
    • Salama, R.B. 1973. Sterols in the seed oil of Nigella sativa. Planta Med. 24:375-377.
    • (1973) Planta Med , vol.24 , pp. 375-377
    • Salama, R.B.1
  • 37
    • 0018870971 scopus 로고
    • Traditional medicine in health care
    • Sayed, M.D. 1980. Traditional medicine in health care. J. Ethnopharmacol. 2:19-22.
    • (1980) J. Ethnopharmacol , vol.2 , pp. 19-22
    • Sayed, M.D.1
  • 38
    • 0020029728 scopus 로고    scopus 로고
    • Study, R.E. and J.L. Baker J.L. 1982. Cellular mechanism of benzodiazepine action. J. Amer Med Assoc. 247:2147-2151.
    • Study, R.E. and J.L. Baker J.L. 1982. Cellular mechanism of benzodiazepine action. J. Amer Med Assoc. 247:2147-2151.
  • 39
    • 0024549518 scopus 로고
    • Differential regulation of G-aminobutyric acid receptor channels by diazepam and Phenobarbital
    • Twyman, R.E., C.J. Rogers, and R.L. Macdonald. 1989). Differential regulation of G-aminobutyric acid receptor channels by diazepam and Phenobarbital. Ann Neurol. 25:213-220.
    • (1989) Ann Neurol , vol.25 , pp. 213-220
    • Twyman, R.E.1    Rogers, C.J.2    Macdonald, R.L.3
  • 40
    • 0015004136 scopus 로고
    • A simple and reliable conflict procedure for testing anti-anxiety agents
    • Vogel, J.R., B. Beer, and D.E. Cldy. 1971. A simple and reliable conflict procedure for testing anti-anxiety agents. Psychopharmacologia. 21:1-7.
    • (1971) Psychopharmacologia , vol.21 , pp. 1-7
    • Vogel, J.R.1    Beer, B.2    Cldy, D.E.3


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