Synthesis and pharmacological investigation of novel 1-alkyl-4-(4- substituted aryl/heteroaryl)-1,2,4-triazolo[4,3-a]quinazolin-5(4H)-ones as a new class of H1-antihistaminic agents

Arzneimittel-Forschung/Drug Research

Volumn 56, Issue 12, 2006, Pages 834-841

  Alagarsamy, Veerachamy ^a   Yadav, Mangae Ram ^b   Giridhar, Rajani ^b  

^a ARULMIGU KALASALINGAM COLLEGE OF PHARMACY   (India)

^b M S UNIVERSITY OF BARODA   (India)

Author keywords

Antihistaminic drugs; Quinazolinones, pharmacology, synthesis, triazole, triazolo pyrimidines

Indexed keywords

1 CHLOROMETHYL 4 (2 PYRIDYL) 1,2,4 TRIAZOLO[4,3 A]QUINAZOLIN 5 (4H) ONE; 1 CHLOROMETHYL 4 (4 METHYLPHENYL) 1,2,4 TRIAZOLO[4,3 A]QUINAZOLIN 5 (4H) ONE; 1 ETHYL 4 (2 PYRIDYL) 1,2,4 TRIAZOLO[4,3 A]QUINAZOLIN 5 (4H) ONE; 1 ETHYL 4 (4 METHYLPHENYL) 1,2,4 TRIAZOLO[4,3 A]QUINAZOLIN 5 (4H) ONE; 1 METHYL 4 (2 PYRIDYL) 1,2,4 TRIAZOLO[4,3 A]QUINAZOLIN 5 (4H) ONE; 1 METHYL 4 (4 METHYLPHENYL) 1,2,4 TRIAZOLO[4,3 A]QUINAZOLIN 5 (4H) ONE; 1 PROPYL 4 (2 PYRIDYL) 1,2,4 TRIAZOLO[4,3 A]QUINAZOLIN 5 (4H) ONE; 1 PROPYL 4 (4 METHYLPHENYL) 1,2,4 TRIAZOLO[4,3 A]QUINAZOLIN 5 (4H) ONE; 1,2,4 TRIAZOLO[4,3 A] QUINAZOLIN 5 (4H) ONE DERIVATIVE; 4 (2 PYRIDYL) 1,2,4 TRIAZOLO[4,3 A] QUINAZOLIN 5 (4H) ONE; 4 (4 METHYLPHENYL) 1,2,4 TRIAZOLO[4,3 A]QUINAZOLIN 5 (4H) ONE; ANTIHISTAMINIC AGENT; CHLORPHENIRAMINE MALEATE; QUINAZOLINE DERIVATIVE; UNCLASSIFIED DRUG;

ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; BRONCHOSPASM; CONTROLLED STUDY; CONVULSION; CYCLIZATION; DRUG ACTIVITY; DRUG EFFECT; DRUG RESEARCH; DRUG SCREENING; DRUG SYNTHESIS; GUINEA PIG; HYPNOSIS; IN VIVO CULTURE; MALE; NONHUMAN; SEDATION;

EID: 33845918657     PISSN: 00044172     EISSN: None     Source Type: Journal    
DOI: 10.1055/s-0031-1296795     Document Type: Article

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