Myelopathy due to intrathecal chemotherapy: magnetic resonance imaging findings

Clinical Radiology

Volumn 62, Issue 2, 2007, Pages 172-176

  Counsel, P ^a   Khangure, M ^a  

^a ROYAL PERTH HOSPITAL   (Australia)

Author keywords

[No Author keywords available]

Indexed keywords

ANTIVIRUS AGENT; CYCLOPHOSPHAMIDE; CYTARABINE; DEXAMETHASONE; DOXORUBICIN; FLUDARABINE; IDARUBICIN; MERCAPTOPURINE; METHOTREXATE; STEROID; VINCRISTINE;

ACUTE LYMPHOBLASTIC LEUKEMIA; ADULT; ARTICLE; CANCER COMBINATION CHEMOTHERAPY; CASE REPORT; DRUG DOSE REDUCTION; DRUG MEGADOSE; DRUG WITHDRAWAL; FEBRILE NEUTROPENIA; FEMALE; HUMAN; IMAGE ANALYSIS; MALE; MULTIPLE CYCLE TREATMENT; NEUROLOGIC EXAMINATION; NUCLEAR MAGNETIC RESONANCE IMAGING; OUTCOME ASSESSMENT; PRIORITY JOURNAL; SPINAL CORD DISEASE; STEM CELL TRANSPLANTATION; STEROID THERAPY; T CELL LYMPHOMA;

ADULT; ANTIMETABOLITES, ANTINEOPLASTIC; CYTARABINE; FEMALE; HUMANS; INJECTIONS, SPINAL; LEUKEMIA, LYMPHOCYTIC, ACUTE; LYMPHOMA, NON-HODGKIN; MAGNETIC RESONANCE IMAGING; MALE; METHOTREXATE; SPINAL CORD; SPINAL CORD DISEASES;

EID: 33845896021     PISSN: 00099260     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.crad.2006.09.005     Document Type: Article

References (13)

1. Kantarjian H.M., O'Brien S., Smith T.L., et al. Results of treatment with hyper-CVAD, a dose-intensive regimen, in adult acute lymphocytic leukemia. J Clin Oncol 18 (2000) 547-561
2. Bratt G., Hammarin A.L., Grandien M., et al. BK virus as the cause of meningoencephalitis, retinitis and nephritis in a patient with AIDS. AIDS 13 (1999) 1071-1075
3. Werner-Wasik M., Yu X., Marks L.B., et al. Normal-tissue toxicities of thoracic radiation therapy: esophagus, lung, and spinal cord as organs at risk. Hematol Oncol Clin North Am 18 (2004) 131-160
4. Watterson J., Toogood I., Nieder M., et al. Excessive spinal cord toxicity from intensive central nervous system-directed therapies. Cancer 74 (1994) 3034-3041
5. Wellwood J., and Taylor K. Central nervous system prophylaxis in haematological malignancies. Intern Med J 32 (2002) 252-258
6. Resar L.M., Phillips P.C., Kastan M.B., et al. Acute neurotoxicity after intrathecal cytosine arabinoside in two adolescents with acute lymphoblastic leukemia of b-cell type. Cancer 71 (1993) 117-123
7. Sherman P.M., Belden C.J., and Nelson D.A. Magnetic resonance imaging findings in a case of cytarabine-induced myelopathy. Mil Med 167 (2002) 157-160
8. García-Tena J., López-Andreu J., Menor F., et al. Intrathecal chemotherapy-related myeloencephalopathy in a young child with acute lymphoblastic leukemia. Pediatr Hematol Oncol 12 (1995) 377-385
9. Raney B., Tefft M., Heyn R., et al. Ascending myelitis after intensive chemotherapy and radiation therapy in children with cranial parameningeal sarcoma. Cancer 69 (1992) 1498-1506
10. Kleinschmidt-DeMasters B.K., and Yeh M. "Locked-in syndrome" after intrathecal cytosine arabinoside therapy for malignant immunoblastic lymphoma. Cancer 70 (1992) 2504-2507
11. McLean D.R., Clink H.M., Ernst P., et al. Myelopathy after intrathecal chemotherapy: a case report with unique magnetic resonance imaging changes. Cancer 73 (1994) 3037-3040
12. Özön A., Topaloǧlu H., Cila A., et al. Acute ascending myelitis and encephalopathy after intrathecal cytosine arabinoside and methotrexate in an adolescent boy with acute lymphoblastic leukaemia. Brain Dev 16 (1994) 246-248
13. Alfonso E.R., De Gregorio M.A., Mateo P., et al. Radiation myelopathy in over-irradiated patients: MR imaging findings. Eur Radiol 7 (1997) 400-404