Interview with Dr. Heikki Rauvala regarding Pivotal Advance: Analysis of proinflammatory activity of highly purified eukaryotic recombinant HMGB1 (amphoterin)

Journal of Leukocyte Biology

Volumn 81, Issue 1, 2007, Pages 46-48

  Bianchi, Marco E ^a  

^a VITA SALUTE SAN RAFFAELE UNIVERSITY   (Italy)

Author keywords

[No Author keywords available]

Indexed keywords

HIGH MOBILITY GROUP B1 PROTEIN; TOLL LIKE RECEPTOR 2; TOLL LIKE RECEPTOR 4;

DNA BINDING; FINLAND; MEDICAL LITERATURE; MEDICAL RESEARCH; NOTE; PRIORITY JOURNAL; PROFESSIONAL PRACTICE; PROTEIN FUNCTION;

ANIMALS; CELL NUCLEUS; HMGB1 PROTEIN; INFLAMMATION; MACROPHAGES; PORTRAITS; RECOMBINANT PROTEINS;

EUKARYOTA;

EID: 33845894166     PISSN: 07415400     EISSN: None     Source Type: Journal    
DOI: 10.1189/jlb.1306200     Document Type: Note

References (6)

1. Rauvala, H., Pihlaskari, R. (1987) Isolation and some characteristics of an adhesive factor in brain that enhances neurite outgrowth in central neurons. J. Biol. Chem. 262, 16625-16635.
2. Rauvala, H., Merenmeri, J., Pihlaskari, R., Korkolainen, M., Huhtala, M.-L., Panula, P. (1988) The adhesive and neurite-promoting molecule p30: analysis of the amino-terminal sequence and production of antipeptide antibodies that detect p30 at the surface of neuroblastoma cells and of brain neurons. J. Cell Biol. 107, 2293-2305.
3. Merenmies, J., Pihlaskari, R., Laitinen, J., Wartiovaara, J., Rauvala, H. (1991) 30-kD heparin-binding protein of brain (amphoterin) involved in neurite outgrowth. Amino acid sequence and localization in the filopodia of the advancing plasma membrane. J. Biol. Chem. 266, 16722-16729.
4. Bianchi, M. E., Beltrame, M., Paonessa, G. (1989) Specific recognition of cruciform DNA by nuclear protein HMG1. Science 243, 1056-1059.
5. Hori, O., Yan, S. D., Ogawa, S., Kuwabara, K., Matsumoto, M., Stern, D., Schmidt, A. M. (1995) The receptor for advanced glycation end products (RAGE) is a cellular binding site for amphoterin. J. Biol. Chem. 270, 25752-25761.
6. Wang, H., Bloom, O., Zhang, M., Vishnubhakat, J. M., Ombrellino, M., Che, J., Frazier, A., Yang, H., Ivanova, S., Borovikova, L., et al. (1999) HMG-1 as a late mediator of endotoxin lethality in mice. Science 285, 248-251.