Platelet glutamate uptake and release in migraine with and without aura

Cephalalgia

Volumn 27, Issue 1, 2007, Pages 35-40

  Vaccaro, M ^a   Riva, C ^b   Tremolizzo, L ^a,b   Longoni, M ^a,b   Aliprandi, A ^a   Agostoni, E ^a   Rigamonti, A ^c   Leone, M ^c   Bussone, G ^c   Ferrarese, C ^a,b  

^a SAN GERARDO HOSPITAL   (Italy)

^b UNIVERSITY OF MILANO BICOCCA   (Italy)

^c DEPARTMENT OF NEUROSURGERY   (Italy)

Author keywords

Glutamate; Migraine; Plasma level; Platelet release; Platelet uptake

Indexed keywords

GLUTAMIC ACID; TRITIUM;

ADOLESCENT; ADULT; AGED; ARTICLE; CLINICAL ARTICLE; CONTROLLED STUDY; FEMALE; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; HUMAN; MALE; MIGRAINE WITH AURA; MIGRAINE WITHOUT AURA; NEUROTRANSMITTER RELEASE; NEUROTRANSMITTER UPTAKE; PATHOPHYSIOLOGY; THROMBOCYTE;

ADOLESCENT; ADULT; AGED; BLOOD PLATELETS; FEMALE; GLUTAMIC ACID; HUMANS; MALE; MIDDLE AGED; MIGRAINE WITH AURA; MIGRAINE WITHOUT AURA;

EID: 33845886959     PISSN: 03331024     EISSN: 14682982     Source Type: Journal    
DOI: 10.1111/j.1468-2982.2006.01234.x     Document Type: Article

References (30)

1. Maragakis NJ, Rothstein JD. Glutamate transporters in neurologic disease. Arch Neurol 2001; 58:365-70.
2. Rothman SM, Olney JW. Glutamate and the pathophysiology of hypoxic ischemic brain damage. Ann Neurol 1986; 19:105-11.
3. Sherwin A, Robitaille Y, Quesney F, Olivier A, Villemure J, Leblanc R et al. Excitatory amino acids are elevated in human epileptic cerebral cortex. Neurology 1988; 38:920-3.
4. Marrannes R, Willems R, De Prins E, Wauquier A. Evidence for a role of the N-methyl-D-aspartate (NMDA) receptor in cortical spreading depression in the rat. Brain Res 1998; 457:226-40.
5. Ramadan NM, Halvorson H, Vande-Linde A, Levine SR, Helpern JA, Welch KMA. Low brain magnesium in migraine. Headache 1989; 29:416-9.
6. Schaumburg HH, Byck R, Gerstl R, Mashman JN. Monosodium 1-glutamate: its pharmacology and role in the Chinese restaurant syndrome. Science 1969; 163:826-8.
7. Alam Z, Coombes N, Waring RH, Williams AC, Steventon GB. Plasma levels of neuroexcitatory amino acids in patients with migraine or tension headache. J Neurol Sci 1998; 156:102-6.
8. Ferrari MD, Odink K, Bos KD, Malessy MKD, Bruyn GW. Neuroexcitatory plasma amino acids are elevated in migraine. Neurology 1990; 40:1582-6.
9. D'Andrea G, Cananzi AR, Joseph R, Morra M, Zamberlan F, Ferro Milone F et al. Platelet glicine, glutamate and aspartate in primary headache. Cephalagia 1991; 11:197-200.
10. Martìnez F, Castillo J, Rodrìguez JR, Leira R, Noya M. Neuroexcitatory amino acid levels in plasma and cerebrospinal fluid during migraine attacks. Cephalalgia 1993; 13:89-93.
11. Hanington E. The platelet and migraine. Headache 1986; 26:411-5.
12. Mangano RM, Schwarcz R. The human platelets as a model for the glutamatergic neuron: platelet uptake of L-glutamate. J Neurochem 1981; 36:1067-76.
13. Headache Classification Committee of the International Headache Society. The International Classification of Headache Disorders, 2nd edition. Cephalalgia 2004;24:1-160.
14. Ferrarese C, Sala G, Riva R, Begni B, Zoia C, Tremolizzo L et al. Decreased platelet glutamate uptake in patients with amyotrophic lateral sclerosis. Neurology 2001; 56:270-2.
15. Ferrarese C, Pecora N, Frigo M, Appollonio I, Frattola L. Assessment of reliability and biological significance of glutamate levels in cerebrospinal fluid. Ann Nerol 1993; 33:316-9.
16. Gorji A, Scheller D, Straub H, Tegtmeier F, Kohling R, Hohling JM et al. Spreading depression in human neocortical slices. Brain Res 2001; 906:74-83.
17. Goadsby PJ, Classey DJ. Glutamatergic transmission in the trigeminal nucleus assessed with local blood flow. Brain Res 2000; 875:119-24.
18. Peres MFP, Zukerman E, Senne Soares CA, Alonso EO, Santos BFC, Faulhaber MHW. Cerebrospinal fluid glutamate levels in chronic migraine. Cephalalgia 2004; 24:735-9.
19. Cananzi AR, D'Andrea G, Perini F, Zamberlan F, Welch KMA. Platelet and plasma levels of glutamate and glutamine in migraine with and without aura. Cephalalgia 1995; 15:132-5.
20. Zoia C, Cogliati T, Tagliabue E, Cavaletti G, Sala G, Galimberti G et al. Glutamate transporters in platelets: EAAT1 decrease in aging and in Alzheimer's disease. Neurobiol Aging 2004; 25:149-57.
21. Tremolizzo L, DiFrancesco JC, Rodriguez-Menendez V, Sirtori E, Longoni M, Cassetti A et al. Human platelets express the synaptic markers VGLUT1 and 2 and release glutamate upon aggregation. Neurosci Lett 2006; 404:262-5.
22. Franconi F, Miceli M, De Montis F, Crisafi EL, Bennardini F, Tagliamonte A. NMDA receptors play an antiaggregating role in human platelets. Thromb Haemost 1996; 76:84-7.
23. Begni B, Tremolizzo L, D'Orlando C, Bono MS, Garofolo R, Longoni M, Ferrarese C. Substrate-induced modulation of glutamate uptake in human platelets. Br J Pharmacol 2005; 145:729-9.
24. Rainesalo S, Keranen T, Peltola J, Saransaari P. Glutamate uptake in blood platelets from epileptic patients. Neurochem Int 2003; 43:389-92.
25. D'Andrea D, Nordera GP, Allais G. Treatment of aura: solving the puzzle. Neurol Sci 2006; 27 (Suppl. 2):s96-9.
26. Welch KMA, Bousser MG. Migraine and stroke. In: Olesen J, Tfelt-Hansen P, Welch KMA, editors. The headaches, 2nd edn. Philadelphia: Lippincott Williams & Wilkins 2000:529-42.
27. Choi DW. Methods for antagonizing glutamate neurotoxicity. Cerebrovasc Brain Metab Rev 1990; 2:105-47.
28. Aliprandi A, Longoni M, Stanzani L, Tremolizzo L, Vaccaro M, Begni B et al. Increased plasma glutamate in stroke patients might be linked to altered platelet release and uptake. J Cereb Blood Flow Metab 2005; 25:513-9.
29. Sangiorgi S, Mochi M, Riva R, Cortelli P, Monari L, Pierangeli G, Montagna P. Abnormal platelet mitochondrial function in patients affected by migraine with and without aura. Cephalalgia 1994; 14:21-3.
30. Mallolas J, Hurtado O, Castellanos M, Blanco M, Sobrino T, Serena J et al. A polymorphism in the EAAT2 promoter is associated with higher glutamate concentrations and higher frequency of progressing stroke. J Exp Med 2006; 203:711-7.