Suppression of AGE precursor formation following unilateral ureteral obstruction in mouse kidneys by transgenic expression of α-dicarbonyl/L- xylulose reductase

Bioscience, Biotechnology and Biochemistry

Volumn 70, Issue 12, 2006, Pages 2899-2905

  Asami, Jun ^a   Odani, Hiroko ^b,c   Ishii, Aiko ^a   Oide, Kayoko ^a   Sudo, Takako ^a   Nakamura, Atsushi ^a   Miyata, Noriyuki ^a   Otsuka, Noboru ^a   Maeda, Kenji ^b,d   Nakagawa, Junichi ^a  

^a TAISHO PHARMACEUTICAL CO LTD   (Japan)

^b NAGOYA UNIVERSITY SCHOOL OF MEDICINE   (Japan)

^c FUJITA HEALTH UNIVERSITY SCHOOL OF MEDICINE   (Japan)

^d Daikou Medical Engineering Institute   (Japan)

Author keywords

3 deoxyglucosone; Advanced glycation endproduct; Dicarbonyl reductase; Transgenic mice; Unilateral ureteral obstruction

Indexed keywords

3-DEOXYGLUCOSONE; ADVANCED GLYCATION ENDPRODUCT; DICARBONYL REDUCTASE; TRANSGENIC MICE; UNILATERAL URETERAL OBSTRUCTION;

ENZYMES; IONIZATION; LIQUID CHROMATOGRAPHY; MASS SPECTROMETRY; PROTEINS;

LIVING SYSTEMS STUDIES;

ADVANCED GLYCATION END PRODUCT; ALDEHYDE REDUCTASE; ENZYME INHIBITOR; L XYLULOSE REDUCTASE; L-XYLULOSE REDUCTASE; UNCLASSIFIED DRUG;

ANIMAL; ARTICLE; BIOSYNTHESIS; DRUG ANTAGONISM; ELECTROSPRAY MASS SPECTROMETRY; GENETICS; IMMUNOHISTOCHEMISTRY; KIDNEY; LIQUID CHROMATOGRAPHY; MALE; METABOLISM; MOUSE; RAT; TRANSGENIC MOUSE; URETER OBSTRUCTION; WISTAR RAT;

ANIMALS; CHROMATOGRAPHY, LIQUID; ENZYME INHIBITORS; GLYCOSYLATION END PRODUCTS, ADVANCED; IMMUNOHISTOCHEMISTRY; KIDNEY; MALE; MICE; MICE, TRANSGENIC; RATS; RATS, WISTAR; SPECTROMETRY, MASS, ELECTROSPRAY IONIZATION; SUGAR ALCOHOL DEHYDROGENASES; URETERAL OBSTRUCTION;

MUS MUSCULUS;

EID: 33845879124     PISSN: 09168451     EISSN: 13476947     Source Type: Journal    
DOI: 10.1271/bbb.60311     Document Type: Article

References (22)

1. Miyata, T., van Ypersele de Strihou, C., Kurokawa, K., and Baynes, J. W., Alterations in nonenzymatic biochemistry in uremia: origin and significance of "carbonyl stress" in long-term uremic complications. Kidney Int., 55, 389-399 (1999).
2. Ueno, Y., Horio, F., Uchida, K., Naito, M., Nomura, H., Kato, Y., Tsuda, T., Toyokuni, S., and Osawa, T., Increase in oxidative stress in kidneys of diabetic Akita mice. Biosci. Biotechnol. Biochem., 66, 869-872 (2002).
3. Schmidt, A. M., Vianna, M., Gerlach, M., Brett, J., Ryan, J., Kao, J., Esposito, C., Hegarty, H., Hurley, W., Clauss, M., Wang, F., Pan, Y. C. E., Tsang, T. C., and Stern, D., Isolation and characterization of two binding proteins for advanced glycosylation end products from bovine lung which are present on the endothelial cell surface. J. Biol. Chem., 267, 14987-14997 (1992).
4. Makita, Z., Radoff, S., Rayfield, E. J., Yang, Z., Skolnik, E., Delaney, V., Friedman, E. A., Cerami, A., and Vlassara, H., Advanced glycation end products in patients with diabetic nephropathy. New Eng. J. Med., 325, 836-842 (1991).
5. Odani, H., Shinzato, T., Matsumoto, Y., Usami, J., and Maeda, K., Increase in three alpha, beta-dicarbonyl compound levels in human uremic plasma: specific in vivo determination of intermediates in advanced Maillard reaction. Biochem. Biophys. Res. Commun., 256, 89-93 (1999).
6. Odani, H., Iijima, K., Nakata, M., Miyata, S., Kusunoki, H., Yasuda, Y., Hiki, Y., Irie, S., Maeda, K., and Fujimoto, D., Identification of N (omega)-carboxymethylarginine, a new advanced glycation endproduct in serum proteins of diabetic patients: possibility of a new marker of aging and diabetes. Biochem. Biophys. Res. Commun., 285, 1232-1236 (2001).
7. Liang, Z.-Q., Hayase, F., and Kato, H., Purification and characterization of NADPH-dependent 2-oxoaldehyde reductase from porcine liver. Eur. J. Biochem., 197, 373-379 (1991).
8. Kanazu, T., Shinoda, M., Nakayama, T., Deyashiki, Y., Hara, A., and Sawada, H., Aldehyde reductase is a major protein associated with 3-deoxyglucosone reductase activity in rat, pig and human livers. Biochem. J., 279, 903-906 (1991).
9. Matsuura, K., Sato, K., Deyashiki, Y., Nakanishi, M., and Hara, A., 3-Deoxyglucosone reductase in dog adrenal glands: identification as aldose reductase. Biol. Pharm. Bull., 18, 1765-1767 (1995).
10. Shinohara, M., Thornalley, P. J., Giardino, I., Beisswenger, P., Thorpe, S. R., Onorato, J., and Brownlee, M., Overexpression of glyoxalase-I in bovine endothelial cells inhibits intracellular advanced glycation endproduct formation and prevents hyperglycemia-induced increases in macromolecular endocytosis. J. Clin. Invest., 101, 1142-1147 (1998).
11. Nakagawa, J., Ishikura, S., Asami, J., Isaji, T., Usami, N., Hara, A., Sakurai, T., Tsuritani, K., Oda, K., Takahashi, M., Yoshimoto, M., Otsuka, N., and Kitamura, K., Molecular characterization of mammalian dicarbonyl/L- xylulose reductase and its localization in kidney. J. Biol. Chem., 277, 17883-17891 (2002).
12. Hutcheson, R. M., Reynolds, V. H., and Touster, O., The reduction of L-xylulose to xylitol by guinea pig liver mitochondria. J. Biol. Chem., 221, 697-709 (1956).
13. El-Kabbani, O., Chung, R. P., Ishikura, S., Usami, N., Nakagawa, J., and Hara, A., Crystallization and preliminary crystallographic analysis of human L-xylulose reductase. Acta Crystallogr. D. Biol. Crystallogr., 58, 1379-1380 (2002).
14. El-Kabbani, O., Carbone, V., Darmanin, C., Ishikura, S., and Hara, A., Structure of the tetrameric form of human L-xylulose reductase: probing the inhibitor-binding site with molecular modeling and site-directed mutagenesis. Proteins, 60, 424-432 (2005).
15. y diabetic model mice: an animal model for the metabolism of renal carbonyl compounds. Exp. Anim., 54, 385-394 (2005).
16. Kawada, N., Moriyama, T., Ando, A., Fukunaga, M., Miyata, T., Kurokawa, K., Imai, E., and Hori, M., Increased oxidative stress in mouse kidney with unilateral ureteral obstruction. Kidney Int., 56, 1004-1013 (1999).
17. Klahr, S., and Morrissey, J., Obstructive nephropathy and renal fibrosis. Am. J. Physiol. Renal Physiol., 283, F861-875 (2002).
18. Niwa, H., Yamamura, K., and Miyazaki, J., Efficient selection for high-expression transfectants with a novel eukaryotic vector. Gene, 108, 193-199 (1991).
19. Suzuki, K., Koh, Y. H., Mizuno, H., Hamaoka, R., and Taniguchi, N., Overexpression of aldehyde reductase protects PC12 cells from the cytotoxicity of methylglyoxal or 3-deoxyglucoson. J. Biochem., 123, 353-357 (1998).
20. Yamaoka, T., Nishimura, C., Yamashita, K., Itakura, M., Yamada, T., Fujimoto, J., and Kokai, Y., Acute onset of diabetic pathological changes in transgenic mice with human aldose reducetase cDNA. Diabetologia, 38, 255-261 (1995).
21. Shah, S. V., Oxidants and iron in chronic kidney disease. Kidney Int., 66 (Supl. 91), S50-S55 (2004).
22. Lane, A. B., and Jenkins, T., Human L-xylulose reductase variation: family and population studies. Ann. Hum. Genet., 49, 227-235 (1985).