메뉴 건너뛰기




Volumn 12, Issue 1-2, 2007, Pages 62-70

Outsourcing lead optimization: constant change is here to stay

Author keywords

[No Author keywords available]

Indexed keywords

2 PYRROLIDONE DERIVATIVE; ADENOSINE A2 RECEPTOR; ADENOSINE RECEPTOR BLOCKING AGENT; ADENOSINE TRIPHOSPHATASE INHIBITOR; ANGIOGENESIS INHIBITOR; ANTIINFLAMMATORY AGENT; ANTINEOPLASTIC AGENT; ARQ 171; ARQ 197; ARQ 501; ARRY 142886; ARRY 438162; AZD 6244; CD135 ANTIGEN; CHEMOKINE RECEPTOR ANTAGONIST; CHEMOKINE RECEPTOR CCR1; CYCLOSPORIN; ENZYME INHIBITOR; EPIDERMAL GROWTH FACTOR RECEPTOR KINASE INHIBITOR; EVT 201; EVT 301; GEMCITABINE; JANUS KINASE 3; MITOGEN ACTIVATED PROTEIN KINASE INHIBITOR; MITOGEN ACTIVATED PROTEIN KINASE P38 INHIBITOR; N METHYL DEXTRO ASPARTIC ACID RECEPTOR BLOCKING AGENT; PROTEIN INHIBITOR; PROTEIN KINASE B INHIBITOR; PROTEIN TYROSINE KINASE INHIBITOR; PS 433540; RECEPTOR BLOCKING AGENT; SEROTONIN 3 ANTAGONIST; TEMOZOLOMIDE; UNCLASSIFIED DRUG; UNINDEXED DRUG; VINCA ALKALOID;

EID: 33845794840     PISSN: 13596446     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.drudis.2006.11.005     Document Type: Review
Times cited : (9)

References (65)
  • 1
    • 2442544477 scopus 로고    scopus 로고
    • Outsourcing lead optimization - the quiet revolution
    • Clark D.E., and Newton C.G. Outsourcing lead optimization - the quiet revolution. Drug Discov. Today 9 (2004) 492-500
    • (2004) Drug Discov. Today , vol.9 , pp. 492-500
    • Clark, D.E.1    Newton, C.G.2
  • 2
    • 33749471348 scopus 로고    scopus 로고
    • Contract drug discovery market is changing as fast as it's growing
    • Heffner S. Contract drug discovery market is changing as fast as it's growing. Genet. Eng. News 26 (2006) 5
    • (2006) Genet. Eng. News , vol.26 , pp. 5
    • Heffner, S.1
  • 3
    • 17644427039 scopus 로고    scopus 로고
    • When science switches shores
    • McCook A. When science switches shores. The Scientist 19 (2005) 36-38
    • (2005) The Scientist , vol.19 , pp. 36-38
    • McCook, A.1
  • 4
    • 33745712502 scopus 로고    scopus 로고
    • Reverse mergers in life science financing
    • Conway B.J. Reverse mergers in life science financing. Genet. Eng. News 26 (2006) 20-22
    • (2006) Genet. Eng. News , vol.26 , pp. 20-22
    • Conway, B.J.1
  • 5
    • 33845724781 scopus 로고    scopus 로고
    • Koppel, T. (2003) Finding new drugs through alliances. Drug Discov. Dev. 12 (http://www.dddmag.com/ShowPR.aspx?PUBCODE=016&ACCT=1600000100&ISSUE=0312&RELTYPE=PR&ORIGRELTYPE=CVS&PRODCODE=00000000&PRODLETT=N; accessed on 28 September 2006)
  • 6
    • 33845797559 scopus 로고    scopus 로고
    • McCoy, M. (2005) ArQule to exit chemistry services. Chem. Eng. News 83 (http://pubs.acs.org/cen/news/83/i40/8340arqule.html; accessed on 28 September 2006)
  • 7
    • 33845796625 scopus 로고    scopus 로고
    • Tripos (2006) Press Release 24 January 2006 (http://investor.tripos.com/phoenix.zhtml?c=112938&p=irol-newsArticle&ID=807512&highlight=; accessed on 28 September 2006)
  • 8
    • 33845736070 scopus 로고    scopus 로고
    • Discovery Partners International (2005) Press Release 29 November (http://phx.corporate-ir.net/phoenix.zhtml?c=121941&p=irol-newsArticle&ID=791063&highlight=; accessed on 28 September 2006)
  • 9
    • 33845759452 scopus 로고    scopus 로고
    • Discovery Partners International (2006) Press Release 12 April (http://phx.corporate-ir.net/phoenix.zhtml?c=121941&p=irol-newsArticle&ID=841937&highlight=; accessed on 28 September 2006)
  • 10
    • 33845758971 scopus 로고    scopus 로고
    • ChemBridge (2004) Press Release 6 February 2004 (http://www.chembridgeresearch.com/press_020604.html; accessed on 28 September 2006)
  • 11
    • 33845810565 scopus 로고    scopus 로고
    • Wall Street Reporter January 18 (2005) Interview with Dr Ge Li, Chairman and CEO, WuXi PharmaTech (http://www.wallstreetreporter.com)
  • 12
    • 33845803731 scopus 로고    scopus 로고
    • Array BioPharma (2005) Press Release 13 December (http://investor.arraybiopharma.com/phoenix.zhtml?c=123810&p=irol-newsArticle&ID=795503&highlight=; accessed on 28 September 2006)
  • 13
    • 33745187616 scopus 로고    scopus 로고
    • Chemistry outsourcing going global
    • Frantz S. Chemistry outsourcing going global. Nat. Rev. Drug Discov. 5 (2006) 362-363
    • (2006) Nat. Rev. Drug Discov. , vol.5 , pp. 362-363
    • Frantz, S.1
  • 14
    • 33845778993 scopus 로고    scopus 로고
    • The Hindu Business Line 14 January (2006) GVK Biosciences to provide research services for Wyeth Pharma (http://www.thehindubusinessline.com/2006/01/14/stories/2006011403320200.htm; accessed on 28 September 2006)
  • 15
    • 33845770010 scopus 로고    scopus 로고
    • Jubilant Organosys (2006) Press Release 14 January (http://www.jubilantbiosys.com/pr5_new.htm; accessed on 28 September 2006)
  • 16
    • 33845804816 scopus 로고    scopus 로고
    • Aurigene (2006) Press Release 10 February (http://www.aurigene.com/shownews.asp?index=85&type=0; accessed on 28 September 2006)
  • 17
    • 33845799708 scopus 로고    scopus 로고
    • BusinessWorld 16 January (2006) The rise of discovery services. http://www.ibef.org/artdisplay.aspx?cat_id=154&art_id=9301; accessed on 28 September 2006)
  • 18
    • 33845758954 scopus 로고    scopus 로고
    • ASINEX (2004) Press Release 22 November (http://www.asinex.com/news/pr200411.html; accessed on 28 September 2006)
  • 19
    • 33845781606 scopus 로고    scopus 로고
    • ASINEX (2005) Press Release 11 July (http://www.asinex.com/news/pr200506.html; accessed on 28 September 2006)
  • 20
    • 33845770360 scopus 로고    scopus 로고
    • Wall Street Reporter 14 March (2006) Interview with Nikolay Savchuk, President and CEO, ChemDiv, Inc (http://www.wallstreetreporter.com)
  • 21
    • 24944451856 scopus 로고    scopus 로고
    • Biotechnology in India
    • Peet N.P. Biotechnology in India. Drug Discov. Today 10 (2005) 1137-1139
    • (2005) Drug Discov. Today , vol.10 , pp. 1137-1139
    • Peet, N.P.1
  • 22
    • 33845751604 scopus 로고    scopus 로고
    • ArQule (2006) Press Release 15 June (http://phx.corporate-ir.net/phoenix.zhtml?c=82991&p=irol-newsArticle&ID=872798&highlight=; accessed on 28 September 2006)
  • 23
    • 33845785314 scopus 로고    scopus 로고
    • ArQule (2006) Press Release 20 June (http://phx.corporate-ir.net/phoenix.zhtml?c=82991&p=irol-newsArticle&ID=873944&highlight=; accessed on 28 September 2006)
  • 24
    • 33845751587 scopus 로고    scopus 로고
    • ArQule (2006) Press Release 1 February (http://phx.corporate-ir.net/phoenix.zhtml?c=82991&p=irol-newsArticle&ID=811587&highlight=; accessed on 28 September 2006)
  • 25
    • 33845737478 scopus 로고    scopus 로고
    • Galapagos (2006) Press Release 13 June (http://www.biofocus.com/pdf/glpg-dpi_en_fin.pdf; accessed on 28 September 2006)
  • 26
    • 33845765303 scopus 로고    scopus 로고
    • Amphora Discovery (2006) Press Release 13 September (http://www.amphoracorp.com/pdf/Products%20&%20Services%20Press%20Release%20FINAL.pdf; accessed on 28 September 2006)
  • 27
    • 33845778515 scopus 로고    scopus 로고
    • Argenta Discovery (2006) Press Release 2 February (http://www.argentadiscovery.com/news/press_releases/020206_drreddys.html; accessed on 28 September 2006)
  • 28
    • 33845734178 scopus 로고    scopus 로고
    • Array Biopharma (2006) Press Release 8 June (http://phx.corporate-ir.net/phoenix.zhtml?c=123810&p=irol-newsArticle&ID=870217&highlight=; accessed on 28 September 2006)
  • 29
    • 33845758070 scopus 로고    scopus 로고
    • Array Biopharma (2006) Press Release 14 September.(http://phx.corporate-ir.net/phoenix.zhtml?c=123810&p=irol-newsArticle&ID=905600&highlight; accessed on 28 September 2006)
  • 30
    • 33845775302 scopus 로고    scopus 로고
    • Array Biopharma (2006) Press Release 26 April (http://phx.corporate-ir.net/phoenix.zhtml?c=123810&p=irol-newsArticle&ID=847652&highlight=; accessed on 28 September 2006)
  • 31
    • 33845728999 scopus 로고    scopus 로고
    • Cerep (2005) Press Release 24 January (http://www.cerep.fr/Cerep/Users/pages/News/PressReleases/2005/168.pdf; accessed on 28 September 2006)
  • 32
    • 33845811530 scopus 로고    scopus 로고
    • Evotec (2005) Press Release 6 March (http://www.evotecoai.com/opencms/export/evotec/en/events/newsevents/06032005; accessed on 28 September 2006)
  • 33
    • 33845757174 scopus 로고    scopus 로고
    • Evotec (2006) Press Release 13 September (http://www.evotec.com/opencms/export/evotec/en/events/newsevents/13092006; accessed on 28 September 2006)
  • 34
    • 33845721817 scopus 로고    scopus 로고
    • Evotec (2006) Press Release 21 September (http://www.evotec.com/opencms/export/evotec/en/events/newsevents/21092006; accessed on 28 September 2006)
  • 35
    • 33845762891 scopus 로고    scopus 로고
    • Albany Molecular Research (2006) Press Release 1 March (http://www.albmolecular.com/news/press/pr196.html; accessed on 28 September 2006)
  • 36
    • 33845797541 scopus 로고    scopus 로고
    • Albany Molecular Research (2005) Press Release 1 November (http://www.albmolecular.com/news/press/pr184.html; accessed on 28 September 2006)
  • 37
    • 33845725249 scopus 로고    scopus 로고
    • Albany Molecular Research (2006) Press Release 18 May (http://www.albmolecular.com/news/press/pr201.html; accessed on 28 September 2006)
  • 38
    • 33845725680 scopus 로고    scopus 로고
    • Pharmacopeia (2003) Press Release 17 March (http://www.pharmacopeia.com/wt/page/press/pr_1112115598; accessed on 28 September 2006)
  • 39
    • 33845723205 scopus 로고    scopus 로고
    • The Hindu Business Line 12 March (2002) gvk bio partners Ricerca for medicinal chemistry (http://www.thehindubusinessline.com/2002/03/12/stories/2002031201950400.htm; accessed on 28 September 2006)
  • 40
    • 33845810584 scopus 로고    scopus 로고
    • Galapagos (2006) Press Release 23 June (http://www.biofocus.com/pdf/dpi_indiachemistry_en.pdf; accessed on 28 September 2006)
  • 41
    • 33845793992 scopus 로고    scopus 로고
    • Peakdale Molecular (2005) Press Release 18 August (http://www.peakdale.co.uk/180805.htm; accessed on 28 September 2006)
  • 42
    • 33845804358 scopus 로고    scopus 로고
    • Peakdale Molecular (2006) Press Release 21 February (http://www.peakdale.co.uk/210206.htm; accessed on 28 September 2006)
  • 43
    • 33845776205 scopus 로고    scopus 로고
    • Enamine (2006) Press Release 17 May (http://www.enamine.net/public/060517.pdf; accessed on 28 September 2006)
  • 44
    • 33845790665 scopus 로고    scopus 로고
    • Nanosyn (2006) Press Release 22 February (http://www.nanosyn.com/pr/na_02_06.php; accessed on 28 September 2006)
  • 45
    • 33845740772 scopus 로고    scopus 로고
    • Chu, W.L. BMS says outsourcing is 'a strategic function asset'. Drug Researcher.com http://www.drugresearcher.com/news/ng.asp?n=70641&m=1DRG918&c=ryfeexkqxsauswg; accessed on 28 September 2006)
  • 46
    • 33845763425 scopus 로고    scopus 로고
    • Jouillié, M. (2006) Outsourcing: blessing or curse? Chem. Eng. News 84, 116 (http://pubs.acs.org/cen/acsnews/84/8439acscomment.html (accessed on 28 September 2006)
  • 47
    • 33845745385 scopus 로고    scopus 로고
    • Albany Molecular Research (2006) Press Release 13 February (http://www.albmolecular.com/news/press/pr195.html; accessed on 28 September 2006)
  • 48
    • 33845780652 scopus 로고    scopus 로고
    • Argenta Discovery (2005) Press Release 15 December (http://www.argentadiscovery.com/news/press_releases/151205_genentech.html; accessed on 28 September 2006)
  • 49
    • 33845774386 scopus 로고    scopus 로고
    • Array Biopharma (2005) Press Release 3 November (http://investor.arraybiopharma.com/phoenix.zhtml?c=123810&p=irol-newsArticle&ID=778537&highlight=; accessed on 28 September 2006)
  • 50
    • 33845743057 scopus 로고    scopus 로고
    • Galapagos (2005) Press Release 7 December (http://www.biofocus.com/pdf/glpg_amgen.pdf; accessed on 28 September 2006)
  • 51
    • 33845725660 scopus 로고    scopus 로고
    • ChemDiv (2005) Press Release 1 September (http://www.chemdiv.com/en/Information/news/news_detail.php?ID=436&PHPSESSID=be7eac0dca407f3d251b2e3c9b3fe708; accessed on 28 September 2006)
  • 52
    • 33845743056 scopus 로고    scopus 로고
    • ChemBridge (2004) Press Release 7 December (http://www.chembridgeresearch.com/press_120704.html; accessed on 28 September 2006)
  • 53
    • 33845745384 scopus 로고    scopus 로고
    • Discovery Partners International (2005) Press Release 26 October (http://phx.corporate-ir.net/phoenix.zhtml?c=121941&p=irol-newsArticle&ID=773102&highlight=; accessed on 28 September 2006)
  • 54
    • 33845780651 scopus 로고    scopus 로고
    • Evotec (2006) Press Release 17 January (http://www.evotec.com/opencms/export/evotec/en/events/newsevents/17012006; accessed on 28 September 2006)
  • 55
    • 33845752069 scopus 로고    scopus 로고
    • Pharmacopeia (2005) Press Release 30 August (http://www.pharmacopeia.com/wt/page/press/pr_1125249167; accessed on 28 September 2006)
  • 56
    • 33845743995 scopus 로고    scopus 로고
    • SCYNEXIS (2005) Press Release 13 October (http://www.scynexis.com/news_events/pr_teijin.asp; accessed on 28 September 2006)
  • 57
    • 33845770340 scopus 로고    scopus 로고
    • Tripos (2005) Press Release 30 August (http://investor.tripos.com/phoenix.zhtml?c=112938&p=irol-newsArticle&ID=750389&highlight=; accessed on 28 September 2006)
  • 58
    • 33845795702 scopus 로고    scopus 로고
    • Pharmacopeia (2004) Press Release 3 May (http://www.pharmacopeia.com/wt/page/press/pr_1112125298; accessed on 28 September 2006)
  • 59
    • 33845774385 scopus 로고    scopus 로고
    • Argenta Discovery (2004) Press Release 4 October (http://www.argentadiscovery.com/news/pdf/argentamerger.pdf; accessed on 28 September 2006)
  • 60
    • 33845793974 scopus 로고    scopus 로고
    • ChemOvation (2004) Press Release 23 November (http://www.chemovation.com/press/pr_spin-off.htm; accessed on 28 September 2006)
  • 61
    • 33845746319 scopus 로고    scopus 로고
    • Discovery Partners International (2005) Press Release 1 March (http://phx.corporate-ir.net/phoenix.zhtml?c=121941&p=irol-newsArticle&ID=680109&highlight=; accessed on 28 September 2006)
  • 62
    • 33845744429 scopus 로고    scopus 로고
    • Galapagos (2005) Press Release 17 October (http://www.biofocus.com/pdf/wholly_uc_release_final.pdf; accessed on 28 September 2006)
  • 63
    • 33845798016 scopus 로고    scopus 로고
    • SCYNEXIS (2006) Press Release 5 January (http://www.scynexis.com/news_events/pr_selcia.asp; accessed on 28 September 2006)
  • 64
    • 33845751112 scopus 로고    scopus 로고
    • People's Daily 12 October (2003) Eli Lilly, Chinese partner set up research lab in Shanghai (http://english.people.com.cn/200310/12/eng20031012_125837.shtml; accessed on 28 September 2006)
  • 65
    • 33845786055 scopus 로고    scopus 로고
    • People's Daily 18 August (2005) Lilly eyes R&D for sales rise (http://english.people.com.cn/200508/18/eng20050818_203188.html; accessed on 28 September 2006)


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.