Non-reporting and inconsistent reporting of race and ethnicity in articles that claim associations among genotype, outcome, and race or ethnicity

Journal of Medical Ethics

Volumn 32, Issue 12, 2006, Pages 724-728

  Shanawani, Hasan ^a   Dame, L ^b   Schwartz, D A ^c   Cook Deegan, R ^b  

^a Henri Ford Hospital   (United States)

^b DUKE UNIVERSITY   (United States)

^c NATIONAL INSTITUTE OF ENVIRONMENTAL HEALTH SCIENCES   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ARTICLE; CLINICAL PROTOCOL; CORRELATION ANALYSIS; ETHNOLOGY; GENETICS; GENOTYPE; INFORMED CONSENT; MEDICAL LITERATURE; MEDICAL RESEARCH; METHODOLOGY; OUTCOMES RESEARCH; PUBLICATION; RACE; RESEARCH ETHICS; RESEARCH SUBJECT;

BIAS (EPIDEMIOLOGY); CONTINENTAL POPULATION GROUPS; DATA COLLECTION; ETHICS, RESEARCH; ETHNIC GROUPS; GENOTYPE; HUMAN EXPERIMENTATION; HUMANS; PERIODICALS; PUBLISHING; RESEARCH DESIGN;

EID: 33845788682     PISSN: 03066800     EISSN: None     Source Type: Journal    
DOI: 10.1136/jme.2005.014456     Document Type: Article

References (48)

1. Cooper R. The role of genetic and environmental factors in cardiovascular disease in African Americans. Am J Med Sci 1999;317:208-13.
2. Sorlie PD, Sharrett AR, Patsch W, et al. The relationship between lipids/ lipoproteins and atherosclerosis in African Americans and whites: the atherosclerosis risk in communities study. Ann Epidemiol 1999;9:149-58.
3. Cooper RS, Zhu X. Racial differences and the genetics of hypertension. Curr Hypertens Rep 2001;3:19-24.
4. Williams MD, Sandler AB. The epidemiology of lung cancer. Cancer Treat Res 2001;105:31-52.
5. Burchard EG, Ziv E, Coyle N, et al. The importance of race and ethnic background in biomedical research and clinical practice. N Engl J Med 2003;348:1170-5.
6. Phimister EG. Medicine and the racial divide. N Engl J Med 2003;348:1081-2.
7. Osborne NG, Feit MD. The use of race in medical research. JAMA 1992;267:275-9.
8. Freedman ML, Reich D, Penney KL, et al. Assessing the impact of population stratification on genetic association studies. Nat Genet 2004;36:388-93.
9. Lander ES, Schork NJ. Genetic dissection of complex traits. Science 1994;265:2037-48.
10. Schwartz RS. Racial profiling in medical research. N Engl J Med 2001;344:1392-3.
11. Goodman AH. Why genes don't count (for racial differences in health). Am J Public Health 2000;90:1699-702.
12. Aldhous P. Geneticist fears 'race-neutral' studies will fail ethnic groups. Nature 2002;418:355-6.
13. LaVeist TA. Segregation, poverty, and empowerment: health consequences of African Americans. In: LaVeist TA, ed. Race, ethnicity, and health: a public health reader. San Francisco: Jossey-Bass, 2002.
14. Williams DR, Collins C. U.S. socioeconomic and racial differences in health: patterns and explanations, In: LaVeist TA, ed. Race, ethnicity, and health: a public health reader. San Francisco:Jossey-Bass, 2002.
15. Risch N, Burchard E, Ziv E, et al. Categorization of humans in biomedical research: genes, race and disease [comment]. Genome Biol 2002;3:2007.
16. Foster MW, Sharp RR. Beyond race: towards a whole-genome perspective on human populations and genetic variation. Nat Rev Genet 2004;5:790-6.
17. Wang VO, Sue S. In the eye of the storm: race and genomics in research and practice. Am Psychol 2005;60:37-45.
18. Bhopal R, Donaldson L. White, European, Western, Caucasian, or what? Inappropriate labeling in research on race, ethnicity, and health. Am J Public Health 1998;88:1303-7.
19. Bennett T, Bhopal R. US health journal editors' opinions and policies on research in race, ethnicity, and health. J Natl Med Assoc 1998;90:401-8.
20. Bhopal R, Kohli H, Rankin J. Editors' practice and views on terminology in ethnicity and health research. Ethn Health 1997,2:223-7.
21. Jones CP, LaVeist TA, Lillie-Blanton M. "Race" in the epidemiologic literature: an examination of the American Journal of Epidemiology, 1921-1990. Am J Epidemiol 1991;134:1079-84.
22. Williams DR, Lavizzo-Mourey R, Warren RC. The concept of race and health status in America. Public Health Rep 1994;109:26-41.
23. Patrick TB, Demiris G, Folk LC, et al. Evidence-6ased retrieval in evidence-based medicine. J Med Libr Assoc 2004;92:196-9.
24. Alderson P, Green S, Higgins J, eds. Cochrane Reviewers' Handbook 4.2.2 [updated march 2004]. In: The Cochrane Library, Issue 1. Chichester: Wiley, 2004.
25. Avenell A, Handoll HH, Grant AM. Lessons for search strategies from a systematic review, in The Cochrane Library, of nutritional supplementation trials in patients after hip fracture. Am J Clin Nutr 2001;73:505-10.
26. Helmer D, Savoie I, Green C, et al. Evidence-based practice: extending the search to find material for the systematic review. Bul Med Libr Assoc 2001;89:346-52.
27. Segel R, Silverstein S, Lerer I, et al. Prevalence of myotonic dystrophy in Israeli Jewish communities: inter-community variation and founder premutations. Am J Med Genet 2003;119A:273-8.
28. Vos M, Adams CH, Victor TC, et al. Polymorphisms and mutations found in the regions flanking exons 5 to 8 of the TP53 gene in a population at high risk for esophageal cancer in South Africa. Cancer Genet Cytogenet 2003;140:23-30.
29. Choma SR, Alberts M, Potgieter HC, et a l. The effect of different apo(a) isoforms an plasminogen activation in block South African subjects. Cardiovasc J South Africa 2003;14:120-4.
30. Fraser DA, Bulat-Kardum L, Knezevic J, et al. Interferon-gamma receptor-1 gene polymorphism in tuberculosis patients from Croatia [see comment]. Scand J Immunol 2003;57:480-4.
31. Pegoraro RJ, Hira B, Rom L, et al. Plasminogen activator inhibitor type 1 (PAI1) and platelet glycoprotein IIIa (PGIIIa) polymorphisms in Black South Africans with pre-eclampsia. Acta Obstet Gynecol Scand 2003;82:313-7.
32. Wall TL, Carr LG, Ehlers CL. Protective association of genetic variation in alcohol dehydrogenase with alcohol dependence in Native American mission Indians [see comment]. Am J Psychiatry 2003;160:41-6.
33. Yi Z, Garrison N, Cohen-Barak O, et al. A 122.5-kilobase deletion of the P gene underlies the high prevalence of oculocutaneous albinism type 2 in the Navajo population. Am J Hum Genet 2003;72:62-72.
34. Offit K, Pierce H, Kirchhoff T, et al. Frequency of CHEK2 1100delC in New York breast cancer cases and controls. BMC Med Genet 2003;4:1.
35. Goffin JR, Chappuis PO, Begin LR, et al. Impact of germline BRCA1 mutations and overexpression of p53 on prognosis and response to treatment following breast carcinoma: 10-year follow up data. Cancer 2003;97:527-36.
36. Tang H, Quertermous T, Rodriguez B, et al. Genetic structure, self-identified race/ethnicity, and confounding in case-control association studies. Am J Hum Genet 2005;76:268-75.
37. Kadam-Pai P, Su XY, Miranda JJ, et al. Ethnic variations of a retinoblastoma susceptibility gene (RB1) polymorphism in eight Asian populations. J Genet 2003;82:33-7.
38. Yang JD, Feng GY, Zhang J, et al. Apolipoprotein E -491 promoter polymorphism is an independent risk factor for Alzheimer's disease in the Chinese population [correction appears in Neurosci Lett 2003;30:215]. Neurosci Lett 2003;350:25-8.
39. Chang YT, Tsai SF, Lin MW, et al. SPR1 gene near HLA-C is unlikely to be a psoriasis susceptibility gene. Exp Dermatol 2003;12:307-14.
40. Hahn RA, Stroup DF. Race and ethnicity in public health surveillance: criteria for the scientific use of social categories. Public Health Rep 1994;109:7-15.
41. Corbie-Smith G, St George DM, Moody-Ayers S, et al. Adequacy of reporting race/ethnicity in clinical trials in areas of health disparities. J Clin Epidemiol 2003;56:416-20.
42. Reiner AP, Ziv E, Lind DL, et al. Population structure, admixture, and aging-related phenotypes in African American adults: the Cardiovascular Health Study. Am J Hum Genet 2005;76:463-77.
43. Krieger N. Stormy weather: race, gene expression, and the science of health disparities. Am J Public Health 2005;95:2155-60.
44. Wilkinson DY, King G. Conceptual and methodological issues in the use of race as a variable: policy implications. Milbank Q 1987;65(Suppl 1):56-71.
45. Phelan JC, Link BG. Controlling disease and creating disparities: a fundamental cause perspective. J Gerontol B Psychol Soc Sci 2005;60(Spec No 2):27-33.
46. Smedley A, Smedley BD. Race as biology is fiction, racism as a social problem is real: anthropological and historical perspectives on the social construction of race. Am Psychol 2005;60:16-26.
47. Bloche MG. American medicine and the politics of race. Perspect Biol Med 2005;48(Suppl 1):S54-67.
48. Rivera JH, Rivera EY. Racial and ethnic disparities in health status and health care: political common ground. Del Med J 2005;77:361-5.