Mechanisms of glutamate receptor induced proliferation of astrocytes

NeuroReport

Volumn 17, Issue 18, 2006, Pages 1877-1881

  Kanumilli, Srinivasan ^a   Roberts, Peter J ^a  

^a UNIVERSITY OF BRISTOL   (United Kingdom)

Author keywords

Metabotropic glutamate receptor; Phosphatidic acid; Phospholipase D; Proliferation

Indexed keywords

2 (2,3 DICARBOXYCYCLOPROPYL)GLYCINE; 2 [1 (3 DIMETHYLAMINOPROPYL) 3 INDOLYL] 3 (3 INDOLYL)MALEIMIDE; 3,5 DIHYDROXYPHENYLGLYCINE; BREFELDIN A; BUTANOL; GLUTAMATE RECEPTOR; METABOTROPIC RECEPTOR 5; METABOTROPIC RECEPTOR ANTAGONIST; PHOSPHATIDIC ACID; PHOSPHOLIPASE D; PROTEIN KINASE C; PROTEIN KINASE INHIBITOR;

ANIMAL CELL; ARTICLE; ASTROCYTE; CELL PROLIFERATION; CONTROLLED STUDY; ENZYME ACTIVITY; NONHUMAN; PRIORITY JOURNAL; PROTEIN FUNCTION; RAT;

ANIMALS; ANIMALS, NEWBORN; ASTROCYTES; CELL COUNT; CELL PROLIFERATION; CELLS, CULTURED; CEREBRAL CORTEX; CYCLOLEUCINE; CYCLOPROPANES; DOSE-RESPONSE RELATIONSHIP, DRUG; DRUG INTERACTIONS; ENZYME INHIBITORS; EXCITATORY AMINO ACID AGONISTS; EXCITATORY AMINO ACID ANTAGONISTS; GLYCEROPHOSPHOLIPIDS; GLYCINE; INDOLES; MALEIMIDES; METHOXYHYDROXYPHENYLGLYCOL; PHOSPHOLIPASE D; PYRIDINES; RATS; RATS, WISTAR; RECEPTORS, GLUTAMATE; TRITIUM;

EID: 33845731810     PISSN: 09594965     EISSN: None     Source Type: Journal    
DOI: 10.1097/WNR.0b013e3280102ee6     Document Type: Article

References (22)

1. Conn PJ, Pin JP. Pharmacology and functions of metabotropic glutamate receptors. Ann Rev Pharmacol Toxicol 1997; 37:205-237.
2. Petralia RS, Wang YX, Niedzielski AS, Wenthold RJ. The metabotropic glutamate receptors, mGluR2 and mGluR3, show unique postsynaptic, presynaptic and glial localizations. Neuroscience 1996; 71:949-976.
3. Hansson E. Metabotropic glutamate receptor activation induces astroglial swelling. J Biol Chem 1994; 269:21955-21961.
4. Miller S, Cotman CW, Bridges RJ. 1-Aminocyclopentane-trans-1, 3-dicarboxylic acid induces glutamine synthetase activity in cultured astrocytes. J Neurochem 1992; 58:1967-1970.
5. Wofchuk ST, Rodnight R. Glutamate stimulates the phosphorylation of glial fibrillary acidic protein in slices of immature rat hippocampus via a metabotropic receptor. Neurochem Int 1994; 24:517-523.
6. Ciccarelli R, Sureda FX, Casabona G, Di Iorio P, Caruso A, Spinella F, et al. Opposite influence of the metabotropic glutamate receptor subtypes mGlu3 and -5 on astrocyte proliferation in culture. Glia 1997; 21:390-398.
7. Kötter K, Klein J. Ethanol inhibits astroglial cell proliferation by disruption of phospholipase D-mediated signalling. J Neurochem 1999; 73:2517-2523.
8. Servitja JM, Masgrau R, Sarri E, Picatoste F. Group I metabotropic glutamate receptors mediate phospholipase D stimulation in rat cultured astrocytes. J Neurochem 1999; 72:1441-1447.
9. +, protein kinase C, tyrosine kinase and Rho-A. Neuropharmacology 2002; 42:1-8.
10. Liao SL, Chen CJ. Tyrosine kinase signaling involved in glutamate-induced astrocyte proliferation. Neuroreport 2001; 21:3519-3522.
11. Cory AH, Owen TC, Barltrop JA, Cory JG. Use of an aqueous soluble tetrazolium/formazan assay for cell growth assays in culture. Cancer Commun 1991; 3:207-212.
12. Servitja JM, Masgrau R, Pardo R, Sarri E, von Eichel-Streiber C, Gutkind JS, et al. Metabotropic glutamate receptors activate phospholipase D in astrocytes through a protein kinase C-dependent and Rho-independent pathway. Neuropharmacology 2003; 44:171-180.
13. Biber K, Laurie DJ, Berthele A, Sommer B, Tölle TR, Gebicke-Härter PJ, et al. Expression and signalling of group I metabotropic glutamate receptors in astrocytes and microglia. J Neurochem 1999; 72:1671-1680.
14. Kingston AE, Ornstein PL, Wright RA, Johnson BG, Mayne NG, Burnett JP, et al. LY341495 is a nanomolar potent and selective antagonist of group II metabotropic glutamate receptors. Neuropharmacology 1998; 37:1-12.
15. Wilkie N, Morton C, Ng LL, Boarder MR. Stimulated mitogen-activated protein kinase is necessary but not sufficient for the mitogenic response to angiotensin II. A role for phospholipase D. J Biol Chem 1996; 271:32447-32453.
16. Pearce B, Albrecht J, Morrow C, Murphy S. Astrocyte glutamate receptor activation promotes inositol phospholipid turnover and calcium influx. Neurosci Lett 1986; 72:335-340.
17. Ulus IH, Wurtman RJ. Metabotropic glutamate receptor agonists increase release of soluble amyloid precursor protein derivatives from rat brain cortical and hippocampal slices. J Pharmacol Exp Ther 1997; 281:149-154.
18. Parpura V, Haydon PG. Physiological astrocytic calcium levels stimulate glutamate release to modulate adjacent neurons. Proc Natl Acad Sci USA 2000; 97:8629-8634.
19. Houle MG, Bourgoin S. Regulation of phospholipase D by phosphorylation-dependent mechanisms. Biochim Biophys Acta 1999; 1439:135-149.
20. Lee MY, Kim SY, Min DS, Choi YS, Shin SL, Chun MH, et al. Upregulation of phospholipase D in astrocytes in response to transient forebrain ischemia. Glia 2000; 30:311-317.
21. Pearce B, Jakobson K, Morrow C, Murphy S. Phosphatidic acid promotes phosphoinositide metabolism and DNA synthesis in cultured cortical astrocytes. Neurochem Int 1994; 24:165-171.
22. Schatter B, Walev I, Klein J. Mitogenic effects of phospholipase D and phosphatidic acid in transiently permeabilized astrocytes: effects of ethanol. J Neurochem 2003; 87:95-100.