Interferon-γ-induced suppression of S100A4 transcription is mediated by the class II transactivator

Tumor Biology

Volumn 28, Issue 1, 2007, Pages 27-35

  Boye, Kjetil ^a   Andersen, Kristin ^a   Tveito, Siri ^a   Øyjord, Tove ^a   Mælandsmo, Gunhild M ^a  

^a OSLO UNIVERSITY HOSPITAL   (Norway)

Author keywords

CBP p300; Class II transactivator; Interferon ; S100A4

Indexed keywords

CALVASCULIN; GAMMA INTERFERON; HISTONE ACETYLTRANSFERASE; HISTONE ACETYLTRANSFERASE PCAF; TRANSACTIVATOR PROTEIN;

AMINO TERMINAL SEQUENCE; ARTICLE; CONTROLLED STUDY; GENE ACTIVITY; GENETIC TRANSCRIPTION; HUMAN; HUMAN CELL; NUCLEOTIDE SEQUENCE; PRIORITY JOURNAL; PROMOTER REGION; PROTEIN BINDING; PROTEIN EXPRESSION;

EID: 33845728076     PISSN: 10104283     EISSN: None     Source Type: Journal    
DOI: 10.1159/000098000     Document Type: Article

References (38)

1. Marenholz I, Heizmann CW, Fritz G: S100 proteins in mouse and man: from evolution to function and pathology (including an update of the nomenclature). Biochem Biophys Res Commun 2004;322:1111-1122.
2. Donato R: Intracellular and extracellular roles of S100 proteins. Microsc Res Tech 2003;60:540-551.
3. Davies BR, Davies MP, Gibbs FE, Barraclough R, Rudland PS: Induction of the metastatic phenotype by transfection of a benign rat mammary epithelial cell line with the gene for p9Ka, a rat calcium-binding protein, but not with the oncogene EJ-ras-1. Oncogene 1993;8:999-1008.
4. Mælandsmo GM, Hovig E, Skrede M, Engebraaten O, Florenes VA, Myklebost O, Grigorian M, Lukanidin E, Scanlon KJ, Fodstad O: Reversal of the in vivo metastatic phenotype of human tumor cells by an anti-CAPL (mts1) ribozyme. Cancer Res 1996;56:5490-5498.
5. Takenaga K, Nakamura Y, Sakiyama S: Expression of antisense RNA to S100A4 gene encoding an S100-related calcium-binding protein suppresses metastatic potential of high-metastatic Lewis lung carcinoma cells. Oncogene 1997;14:331-337.
6. Ford HL, Salim MM, Chakravarty R, Aluiddin V, Zain SB: Expression of Mts1, a metastasis-associated gene, increases motility but not invasion of a nonmetastatic mouse mammary adenocarcinoma cell line. Oncogene 1995;11:2067-2075.
7. Belot N, Pochet R, Heizmann CW, Kiss R, Decaestecker C: Extracellular S100A4 stimulates the migration rate of astrocytic tumor cells by modifying the organization of their actin cytoskeleton. Biochim Biophys Acta 2002;1600:74-83.
8. Bjornland K, Winberg JO, Odegaard OT, Hovig E, Loennechen T, Aasen AO, Fodstad O, Mælandsmo GM: S100A4 involvement in metastasis: deregulation of matrix metalloproteinases and tissue inhibitors of matrix metalloproteinases in osteosarcoma cells transfected with an anti-S100A4 ribozyme. Cancer Res 1999;59:4702-4708.
9. Schmidt-Hansen B, Ornas D, Grigorian M, Klingelhofer J, Tulchinsky E, Lukanidin E, Ambartsumian N: Extracellular S100A4(mts1) stimulates invasive growth of mouse endothelial cells and modulates MMP-13 matrix metalloproteinase activity. Oncogene 2004;23:5487-5495.
10. Ambartsumian N, Klingelhofer J, Grigorian M, Christensen C, Kriajevska M, Tulchinsky E, Georgiev G, Berezin V, Bock E, Rygaard J, Cao R, Cao Y, Lukanidin E: The metastasis-associated Mts1(S100A4) protein could act as an angiogenic factor. Oncogene 2001;20:4685-4695.
11. Semov A, Moreno MJ, Onichtchenko A, Abulrob A, Ball M, Ekiel I, Pietrzynski G, Stanimirovic D, Alakhov V: Metastasis-associated protein S100A4 induces angiogenesis through interaction with annexin II and accelerated plasmin formation. J Biol Chem 2005;280:20833-20841.
12. Okada H, Danoff TM, Kalluri R, Neilson EG: Early role of Fsp1 in epithelial-mesenchymal transformation. Am J Physiol 1997;273:F563-F574.
13. Hernan R, Fasheh R, Calabrese C, Frank AJ, Maclean KH, Allard D, Barraclough R, Gilbertson RJ: ERBB2 up-regulates S100A4 and several other prometastatic genes in medulloblastoma. Cancer Res 2003;63:140-148.
14. Grigorian M, Tulchinsky E, Burrone O, Tarabykina S, Georgiev G, Lukanidin E: Modulation of mts1 expression in mouse and human normal and tumor cells. Electrophoresis 1994;15:463-468.
15. Chiaramonte R, Fasola S, Lollini PL, De Giovanni C, Comi P: Is mts1(S100A4) gene involved in the metastatic process modulated by γ-interferon? Pathobiology 1998;66:38-40.
16. Takenaga K: Suppression of metastasis-associated S100A4 gene expression by γ-interferon in human colon adenocarcinoma cells. Br J Cancer 1999;80:127-132.
17. Andersen K, Smith-Sorensen B, Pedersen KB, Hovig E, Myklebost O, Fodstad O, Mælandsmo GM: Interferon-γ suppresses S100A4 transcription independently of apoptosis or cell cycle arrest. Br J Cancer 2003;88:1995-2001.
18. Boehm U, Klamp T, Groot M, Howard JC: Cellular responses to interferon-γ. Annu Rev Immunol 1997;15:749-795.
19. Stark GR, Kerr IM, Williams BR, Silverman RH, Schreiber RD: How cells respond to interferons. Annu Rev Biochem 1998;67:227-264.
20. Xu Y, Wang L, Buttice G, Sengupta PK, Smith BD: Major histocompatibility class II transactivator (CIITA) mediates repression of collagen (COL1A2) transcription by interferon-γ (IFN-γ). J Biol Chem 2004;279:41319-41332.
21. Sharma B, Iozzo RV: Transcriptional silencing of perlecan gene expression by interferon-γ. J Biol Chem 1998;273:4642-4646.
22. Dodge GR, Diaz A, Sanz-Rodriguez C, Reginato AM, Jimenez SA: Effects of interferon-γ and tumor necrosis factor alpha on the expression of the genes encoding aggrecan, biglycan, and decorin core proteins in cultured human chondrocytes. Arthritis Rheum 1998;41:274-283.
23. Cocks BG, Vairo G, Bodrug SE, Hamilton JA: Suppression of growth factor-induced CYL1 cyclin gene expression by antiproliferative agents. J Biol Chem 1992;267:12307-12310.
24. Sibinga NE, Wang H, Perrella MA, Endege WO, Patterson C, Yoshizumi M, Haber E, Lee ME: Interferon-γ-mediated inhibition of cyclin A gene transcription is independent of individual cis-acting elements in the cyclin A promoter. J Biol Chem 1999;274:12139-12146.
25. Donnelly RP, Freeman SL, Hayes MP: Inhibition of IL-10 expression by IFN-γ up-regulates transcription of TNF-α in human monocytes. J Immunol 1995;155:1420-1427.
26. Dickensheets HL, Donnelly RP: Inhibition of IL-4-inducible gene expression in human monocytes by type I and type II interferons. J Leukoc Biol 1999;65:307-312.
27. Ting JP, Trowsdale J: Genetic control of MHC class II expression. Cell 2002;109 (suppl):S21-S33.
28. 2(I) and other promoters. Mol Cell Biol 2001;21:7078-7088.
29. Sisk TJ, Gourley T, Roys S, Chang CH: MHC class II transactivator inhibits IL-4 gene transcription by competing with NF-AT to bind the coactivator CREB binding protein (CBP)/p300. J Immunol 2000;165:2511-2517.
30. Nozell S, Ma Z, Wilson C, Shah R, Benveniste EN: Class II major histocompatibility complex transactivator (CIITA) inhibits matrix metalloproteinase-9 gene expression. J Biol Chem 2004;279:38577-38589.
31. Yee CS, Yao Y, Li P, Klemsz MJ, Blum JS, Chang CH: Cathepsin E: a novel target for regulation by class II transactivator. J Immunol 2004;172:5528-5534.
32. Fodstad O, Brogger A, Bruland O, Solheim OP, Nesland JM, Pihl A: Characteristics of a cell line established from a patient with multiple osteosarcoma, appearing 13 years after treatment for bilateral retinoblastoma. Int J Cancer 1986;38:33-40.
33. Gluzman Y: SV40-transformed simian cells support the replication of early SV40 mutants. Cell 1981;23:175-182.
34. Pedersen KB, Andersen K, Fodstad O, Mælandsmo GM: Sensitization of interferon-γ induced apoptosis in human osteosarcoma cells by extracellular S100A4. BMC Cancer 2004;4:52.
35. Engelkamp D, Schafer BW, Mattei MG, Erne P, Heizmann CW: Six S100 genes are clustered on human chromosome 1q21: identification of two genes coding for the two previously unreported calcium-binding proteins S100D and S100E. Proc Natl Acad Sci USA 1993;90:6547-6551.
36. Jabrane-Ferrat N, Nekrep N, Tosi G, Esserman L, Peterlin BM: MHC class II enhanceosome: how is the class II transactivator recruited to DNA-bound activators? Int Immunol 2003;15:467-475.
37. Chawla-Sarkar M, Lindner DJ, Liu YF, Williams BR, Sen GC, Silverman RH, Borden EC: Apoptosis and interferons: role of interferon-stimulated genes as mediators of apoptosis. Apoptosis 2003;8:237-249.
38. Reith W, LeibundGut-Landmann S, Waldburger JM: Regulation of MHC class II gene expression by the class II transactivator. Nat Rev Immunol 2005;5:793-806.