Genetic predisposition to asthma and atopy

Respiration

Volumn 74, Issue 1, 2006, Pages 8-12

  Contopoulos Ioannidis, Despina G ^a,b   Kouri, Ioanna N ^a   Ioannidis, John P A ^a,c  

^a UNIVERSITY OF IOANNINA   (Greece)

^b GEORGE WASHINGTON UNIVERSITY SCHOOL OF MEDICINE AND HEALTH SCIENCES   (United States)

^c University Campus ^*  (Greece)

Author keywords

Asthma; Atopy; Genetics; Linkage; Polymorphism

Indexed keywords

ADAM PROTEIN; ADAM33 PROTEIN; BETA 2 ADRENERGIC RECEPTOR; CD14 ANTIGEN; IMMUNOGLOBULIN E; LEUKOTRIENE C4 SYNTHASE; TUMOR NECROSIS FACTOR ALPHA; UNCLASSIFIED DRUG;

ARTICLE; ASTHMA; ATOPY; CHROMOSOME 10; CHROMOSOME 11; CHROMOSOME 15; CHROMOSOME 2; CHROMOSOME 4; CHROMOSOME 6; CHROMOSOME 9; GENE IDENTIFICATION; GENE LOCUS; GENETIC ANALYSIS; GENETIC ASSOCIATION; GENETIC LINKAGE; GENETIC POLYMORPHISM; GENETIC PREDISPOSITION; GENETIC SUSCEPTIBILITY; GENETIC VARIABILITY; HUMAN; IMMUNOGLOBULIN BLOOD LEVEL; INHERITANCE; MEDICAL LITERATURE; MEDLINE; PHENOTYPE; PRIORITY JOURNAL; SAMPLE SIZE; STANDARDIZATION;

ASTHMA; GENETIC PREDISPOSITION TO DISEASE; GENOTYPE; HUMANS; HYPERSENSITIVITY; LINKAGE (GENETICS); POLYMORPHISM, GENETIC;

EID: 33845723172     PISSN: 00257931     EISSN: None     Source Type: Journal    
DOI: 10.1159/000096833     Document Type: Article

References (26)

1. Aoki T, Hirota T, Tamari M, Ichikawa K, Takeda K, Arinami T, Shibasaki M, Noguchi E: An association between asthma and TNF -308G/A polymorphism: meta-analysis. J Hum Genet 2006;51:677-685.
2. Gao J, Shan G, Sun B, Thompson PJ, Gao X: Association between polymorphism of tumour necrosis factor alpha-308 gene promoter and asthma: a meta-analysis. Thorax 2006;61:466-471.
3. Hall IP, Blakey JD, Al Balushi KA, Wheatley A, Sayers I, Pembrey ME, Ring SM, McArdle WL, Strachan DP: Beta2-adrenoceptor polymorphisms and asthma from childhood to middle age in the British 1958 birth cohort: a genetic association study. Lancet 2006;368:771-779.
4. Contopoulos-Ioannidis DG, Manoli EN, Ioannidis JP: Meta-analysis of the association of beta2-adrenergic receptor polymorphisms with asthma phenotypes. J Allergy Clin Immunol 2005;115:963-972.
5. Migita O, Noguchi E, Jian Z, Shibasaki M, Migita T, Ichikawa K, Matsui A, Arinami T: ADRB2 polymorphisms and asthma susceptibility: transmission disequilibrium test and meta-analysis. Int Arch Allergy Immunol 2004;134:150-157.
6. Thakkinstian A, McEvoy M, Minelli C, Gibson P, Hancox B, Duffy D, Thompson J, Hall I, Kaufman J, Leung TF, Helms PJ, Hakonarson H, Halpi E, Navon R, Attia J: Systematic review and meta-analysis of the association between beta2-adrenoceptor polymorphisms and asthma: a HuGE review. Am J Epidemiol 2005;162:201-211.
7. Blakey J, Halapi E, Bjornsdottir US, Wheatley A, Kristinsson S, Upmanyu R, Stefansson K, Hakonarson H, Hall IP: Contribution of ADAM33 polymorphisms to the population risk of asthma. Thorax 2005;60:274-276.
8. Kedda MA, Duffy DL, Bradley B, O'Hehir RE, Thompson PJ: ADAM33 haplotypes are associated with asthma in a large Australian population. Eur J Hum Genet 2006;14:1027-1036.
9. Kedda MA, Lose F, Duffy D, Bell E, Thompson PJ, Upham J: The CD14 C-159T polymorphism is not associated with asthma or asthma severity in an Australian adult population. Thorax 2005;60:211-214.
10. Kedda MA, Shi J, Duffy D, Phelps S, Yang I, O'Hara K, Fong K, Thompson PJ: Characterization of two polymorphisms in the leukotriene C4 synthase gene in an Australian population of subjects with mild, moderate, and severe asthma. J Allergy Clin Immunol 2004;113:889-895.
11. Van Eerdewegh P, Little RD, Dupuis J, Del Mastro RG, Falls K, Simon J, Torrey D, Pandit S, McKenny J, Braunschweiger K, Walsh A, Liu Z, Hayward B, Folz C, Manning SP, Bawa A, Saracino L, Thackston M, Benchekroun Y, Capparell N, Wang M, Adair R, Feng Y, Dubois J, FitzGerald MG, Huang H, Gibson R, Allen KM, Pedan A, Danzig MR, Umland SP, Egan RW, Cuss FM, Rorke S, Clough JB, Holloway JW, Holgate ST, Keith TP: Association of the ADAM33 gene with asthma and bronchial hyperresponsiveness. Nature 2002;418:426-430.
12. Markianos K, Carlson S, Gibbs M, Kruglyak L: A joint analysis of asthma affection status and IgE levels in multiple data sets collected for asthma. Genet Epidemiol 2001;21(suppl 1):S148-S153.
13. Iyengar SK, Jacobs KB, Palmer LJ: Improved evidence for linkage on 6p and 5p with retrospective pooling of data from three asthma genome screens. Genet Epidemiol 2001;21(suppl 1):S130-S135.
14. Waldman ID, Robinson BF: Meta-analysis of sib pair linkage studies of asthma and the interleukin-9 gene (IL9). Genet Epidemiol 2001;21(suppl 1):S109-S114.
15. Jacobs KB, Burton PR, Iyengar SK, Elston RC, Palmer LJ: Pooling data and linkage analysis in the chromosome 5q candidate region for asthma. Genet Epidemiol 2001;21(suppl 1):S103-S108.
16. Etzel CJ, Costello TJ: Assessing linkage of immunoglobulin E using a meta-analysis approach. Genet Epidemiol 2001;21(suppl 1):S97-S102.
17. Wise LH: Inclusion of candidate region studies in meta-analysis using the genome screen meta-analysis method: application to asthma data. Genet Epidemiol 2001;21(suppl 1):S160-S165.
18. Morar N, Willis-Owen SA, Moffatt MF, Cookson WO: The genetics of atopic dermatitis. J Allergy Clin Immunol 2006;118:24-34.
19. Contopoulos-Ioannidis DG, Alexiou G, Gouvias T, Ioannidis JPA: An empirical evaluation of multifarious outcomes in pharmacogenetics. Pharmacogenet Genomics 2006;16:705-711.
20. Ioannidis JP: Genetic associations: false or true? Trends Mol Med 2003;9:135-138.
21. Ioannidis JPA, Trikalinos TA, Khoury MJ: Implications of small effect sizes of individual genetic variants on the design and interpretation of genetic association studies of complex diseases. Am J Epidemiol 2006;164:609-614.
22. Ioannidis JP, Ntzani EE, Trikalinos TA, Contopoulos-Ioannidis DG: Replication validity of genetic association studies. Nat Genet 2001;29:306-309.
23. Hunter DG: Gene-environment interactions in human diseases. Nat Rev Genet 2005;6:287-298.
24. Ioannidis JP: Why most published research findings are false. PLoS Med, August 2005, e124.
25. Wacholder S, Chanock S, Garcia-Closas M, El Ghormli L, Rothman N: Assessing the probability that a positive report is false: an approach for molecular epidemiology studies. J Natl Cancer Inst 2004;96:434-442.
26. Evans DM, Cardon LR: Genome-wide association: a promising start to a long race. Trend Genet 2006;22:350-354.