Myeloma-related disorders in cats commonly present as extramedullary neoplasms in contrast to myeloma in human patients: 24 Cases with clinical follow-up

Journal of Veterinary Internal Medicine

Volumn 20, Issue 6, 2006, Pages 1376-1383

  Mellor, Paul J ^a   Haugland, Sean ^a   Murphy, Sue ^b   Smith, Ken C ^b   Holloway, Andrew ^a   Archer, Joy ^a   Powell, Roger M ^a   Polton, Gerry A ^c   Tasker, Severine ^d   McCormick, David ^e   Tempest, Michelle E ^f   McNeil, Pauline E ^g   Scase, Timothy J ^b   Knott, Chris D ^g   Bonfanti, Ugo ^h   Villiers, Elizabeth J ^a   Argyle, David J ⁱ   Herrtage, Michael E ^a   Day, Michael J ^d  

^a UNIVERSITY OF CAMBRIDGE   (United Kingdom)

^b ANIMAL HEALTH TRUST   (United Kingdom)

^c DAVIES VETERINARY SPECIALISTS   (United Kingdom)

^d UNIVERSITY OF BRISTOL   (United Kingdom)

^e Runnymede Hill Veterinary Hospital   (United Kingdom)

^f ADDENBROOKE S HOSPITAL   (United Kingdom)

^g Finn Pathologists   (United Kingdom)

^h Clinica Veterinaria Gran Sasso   (Italy)

ⁱ UNIVERSITY OF EDINBURGH   (United Kingdom)

Author keywords

Cat; Extramedullary plasmacytoma; Hyperglobulinemia; Monoclonal gammopathy; Multiple myeloma; Paraproteinemia; Plasma cell tumor

Indexed keywords

ANIMAL; ANIMAL DISEASE; ANTIBODY SPECIFICITY; ARTICLE; BONE; CAT; CAT DISEASE; CLINICAL TRIAL; COMPARATIVE STUDY; DIFFERENTIAL DIAGNOSIS; DOG; FEMALE; GRANULOCYTIC SARCOMA; HUMAN; MALE; MULTICENTER STUDY; MULTIPLE MYELOMA; PATHOLOGY; RADIOGRAPHY; RETROSPECTIVE STUDY; SPECIES DIFFERENCE; SURVIVAL;

ANIMALS; BONE AND BONES; CAT DISEASES; CATS; DIAGNOSIS, DIFFERENTIAL; DOGS; FEMALE; HUMANS; MALE; MULTIPLE MYELOMA; ORGAN SPECIFICITY; RETROSPECTIVE STUDIES; SARCOMA, GRANULOCYTIC; SPECIES SPECIFICITY; SURVIVAL ANALYSIS;

ANIMALIA; CANIS FAMILIARIS;

EID: 33845711398     PISSN: 08916640     EISSN: None     Source Type: Journal    
DOI: 10.1892/0891-6640(2006)20[1376:MDICCP]2.0.CO;2     Document Type: Article

References (47)

1. Carpenter JL, Andrews LK, Holzworth J. Tumours and tumour-like lesions. In: Holzworth J, ed. Diseases of the Cat: Medicine and Surgery. Philadelphia, PA: WB Saunders; 1987:406-596.
2. Engle GC, Brody RS. A retrospective study of 395 feline neoplasms. J Am Anim Hosp Assoc 1969;5:21-31.
3. Priester WA. The occurrence of tumours in domestic animals. NCI monograph 1980;54.
4. Longo DL. Plasma cell disorders. In: Fauci AS, ed. Harrison's Principles of Internal Medicine, 14th ed. New York, NY: McGraw-Hill; 1998:712-718.
5. The UK Myeloma Forum. Guideline diagnosis and management of multiple myeloma. Br J Haematol 2001;115:522-540.
6. Vail DM. Plasma cell neoplasms. In: Withrow SJ, MacEwen EG, eds. Small Animal Clinical Oncology, 3rd ed. Philadelphia, PA: WB Saunders; 2001:626-638.
7. International Myeloma Working Group. Criteria for the classification of monoclonal gammopathies, multiple myeloma and related disorders: A report of the International Myeloma Working Group. Br J Haematol 2003;121:749-757.
8. Carothers MA, Johnson GC, DiBartola SP, et al. Extramedullary plasmacytoma and immunoglobulin-associated amyloidosis in a cat. J Am Vet Med Assoc 1989;195:1593-1597.
9. Larsen AE, Carpenter JL. Hepatic plasmacytoma and biclonal gammopathy in a cat. J Am Vet Med Assoc 1994;205:708-710.
10. Alexiou C, Kau RJ, Dietzfelbinger H, et al. Extramedullary plasmacytoma: Tumor occurrence and therapeutic concepts. Cancer 1999;85:2305-2314.
11. Kapadia SB. Multiple myeloma: A clinicopathologic study of 62 consecutively autopsied cases. Medicine (Baltimore) 1980;59:380-392.
12. Soutar R, Lucraft H, Jackson G, et al. Guidelines on the diagnosis and management of solitary plasmacytoma of bone and solitary extramedullary plasmacytoma. Br J Haematol 2004;124:717-726.
13. MacEwen EG, Hurvitz AI. Diagnosis and management of monoclonal gammopathies. Vet Clin North Am Small Anim Pract 1977;7:119-132.
14. Mills JN, Eger CE, Robinson WF, et al. A case of multiple myeloma in a cat. J Am Anim Hosp Assoc 1982;18:79-82.
15. Forrester SD, Greco DS, Relford RL. Serum hyperviscosity syndrome associated with multiple myeloma in two cats. J Am Vet Med Assoc 1992;200:79-82.
16. Hay LE. Multiple myeloma in a cat. Aust Vet Pract 1978;8:45-48.
17. Jacobs T. Multiple myeloma in a cat with paraparesis. Feline Pract 1994;22:28-32.
18. Harbison ML. Plasma cell myeloma and plasmacytoma. In: Holzworth J, ed. Diseases of the Cat - Medicine and Surgery. Philadelphia, PA: WB Saunders; 1987:442-444.
19. Sheafor SE, Gamblin RM, Couto CG. Hypercalcaemia in two cats with multiple myeloma. J Am Anim Hosp Assoc 1996;32:503-508.
20. Drazner FH. Multiple myeloma in the cat. Comp Cont Educ Pract Vet 1982;4:206-216.
21. King AJ, Davies DR, Irwin PJ. Feline multiple myeloma: Literature review and four case reports. Aust Vet Pract 2002;32:146-151.
22. Hanna F. Multiple myelomas in cats. J Feline Med Surg 2005;7:275-287.
23. Weber NA, Tebeau CS. An unusual presentation of multiple myeloma in 2 cats. J Am Anim Hosp Assoc 1998;34:477-483.
24. Clark GN, Berg H, Engler SJ, et al. Extramedullary plasmacytomas in dogs: Results of surgical excision in 131 cases. J Am Anim Hosp Assoc 1992;28:105-111.
25. Dust A, Norris AM, Valli VEO. Cutaneous lymphosarcoma with IgG immunoglobulin monoclonal gammopathy, serum hyperviscosity and hypercalcaemia in a cat. Can Vet J 1982;23:235-239.
26. Radhakrishnan A, Risbon RE, Patel RT, et al. Progression of a solitary, malignant cutaneous plasma-cell tumour to multiple myeloma in a cat. Vet Comp Oncol 2004;2:36-42.
27. Lester SJ, Mesfin GM. A solitary plasmacytoma in a dog with progression to a disseminated myeloma. Can Vet J 1980;21:284-286.
28. Majzoub M, Breuer W, Platz SJ, et al. Histopathologic and immunophenotypic characterization of extramedullary plasmacytomas in 9 cats. Vet Pathol 2003;40:249-253.
29. Lyon KF. Feline lymphoplasmacytic stomatitis associated with monoclonal gammopathy and Bence-Jones proteinuria. J Vet Dent 1994;11:25-27.
30. Meis JM, Butler JJ, Osborne BM, et al. Solitary plasmacytomas of bone and extramedullary plasmacytomas: A clinicopathologic and immunohistochemical study. Cancer 1987;59:1475-1485.
31. MacEwen EG, Patnaik AK, Johnson GF, et al. Extramedullary plasmacytoma of the gastrointestinal tract in 2 dogs. J Am Vet Med Assoc 1984;184:1396-1398.
32. Homma K, Ihzumi T, Nemoto K, et al. Primary extramedullary plasmacytoma of the small intestine. Int J Hematol 1992;56:179-184.
33. Trevor PB, Saunders GK, Waldron DR, et al. Metastatic extramedullary plasmacytoma of the colon and rectum in a dog. J Am Vet Med Assoc 1993;203:406-409.
34. Michau TM, Proulx DR, Rushton SD, et al. Intraocular extramedullary plasmacytoma in a cat. Vet Ophthalmol 2003;6:177-181.
35. Williams DA, Goldschmidt MH. Hyperviscosity syndrome with IgM monoclonal gammopathy and hepatic plasmacytoid lymphosarcoma in a cat. J Small Anim Pract 1982;23:311-323.
36. Ward DA, McEntee MF, Weddle DL. Orbital plasmacytoma in a cat. J Small Anim Pract 1997;38:576-578.
37. Mandel NS, Esplin DG. A retroperitoneal extramedullary plasmacytoma in a cat with monoclonal gammopathy. J Am Anim Hosp Assoc 1994;20:603-608.
38. Zikes CD, Spielman B, Shapiro W, et al. Gastric extramedullary plasmacytoma in a cat. J Vet Intern Med 1998;12:381-383.
39. Terpos E, Politou M, Rahemtulla A. New insights into the pathophysiology and management of bone disease in multiple myeloma. Br J Haematol 2003;123:758-769.
40. Hawkins EC, Feldman BF, Blanchard PC. Immunoglobulin A myeloma in a cat with pleural effusion and serum hyperviscosity. J Am Vet Med Assoc 1986;188:876-878.
41. Bienzle D, Silverstein DC, Chaffin K. Multiple myeloma in cats: Variable presentation with different immunoglobulin isotypes in 2 cats. Vet Pathol 2000;37:364-369.
42. Mehta J, Singhal S. Hyperviscosity syndrome in plasma cell dyscrasias. Semin Thromb Hemost 2003;29:467-471.
43. Sirohi B, Powles R. Multiple myeloma. Lancet 2004;363:875-887.
44. Janz S, Muller J, Shaughnessy J, et al. Detection of recombinations between c-myc and immunoglobulin switch alpha in murine plasma cell tumors and preneoplastic lesions by polymerase chain reaction. Proc Natl Acad Sci U S A 1993;90:7361-7365.
45. Potter M, Mushinski EB, Wax JS, et al. Identification of 2 genes on chromosome 4 that determine resistance to plasmacytoma induction in mice. Cancer Res 1994;54:969-975.
46. Speer SA, Semenza JC, Kurosaki T, et al. Risk factors for acute myeloid leukemia and multiple myeloma: A combination of GIS and case-control studies. J Environ Health 2002;64:9-16; quiz 35-16.
47. Schattner A, Berrebi A. Several possible causes for multiple myeloma including a vaccination in a single case study. Vaccine 2004;22:2509-2510.