Improvement in HPLC separation of porphyrin isomers and application to biochemical diagnosis of porphyrias

Clinical Chemistry and Laboratory Medicine

Volumn 44, Issue 12, 2006, Pages 1433-1440

  Macours, Pascale ^a   Cotton, Frédéric ^a  

^a ERASME HOSPITAL   (Belgium)

Author keywords

Biochemical diagnosis; HPLC; Porphyria; Porphyrin

Indexed keywords

ACETONITRILE; AMMONIUM ACETATE; METHANOL; PORPHYRIN; WATER;

ARTICLE; DIAGNOSTIC ACCURACY; DIAGNOSTIC APPROACH ROUTE; DIAGNOSTIC TEST; ELUTION; ENZYME ISOLATION; FECES ANALYSIS; FLUOROMETRY; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; ISOMER; PH MEASUREMENT; PLASMA; PORPHYRIA; PRIORITY JOURNAL; QUANTITATIVE ANALYSIS; RELIABILITY; REVERSED PHASE HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; SEPARATION TECHNIQUE;

CALIBRATION; CHROMATOGRAPHY, HIGH PRESSURE LIQUID; COPROPORPHYRINS; FECES; HUMANS; ISOMERISM; PORPHYRIAS; PORPHYRINS; PROTOPORPHYRINS; REPRODUCIBILITY OF RESULTS; SENSITIVITY AND SPECIFICITY; UROPORPHYRINS;

EID: 33845704589     PISSN: 14346621     EISSN: 14346621     Source Type: Journal    
DOI: 10.1515/CCLM.2006.266     Document Type: Article

References (25)

1. de Verneuil H, Beaumont C, Deybach JC, Nordman Y, Sfar Z, Kastally R. Enzymatic and immunological studies of uroporphyrinogen decarboxylase in familial porphyria cutanea tarda and hepatoerythropoietic porphyria. Am J Hum Genet 1984;36:613-22.
2. De Rooij FW, Edixhoven A, Wilson JH. Porphyria: a diagnostic approach. The porphyrin handbook, vol 14. St. Louis: Elsevier, 2003:211-45.
3. Elder GH, Smith SG, Smyth SJ. Laboratory investigation of the porphyrias. Ann Clin Biochem 1990;27:395-412.
4. Deacon AC, Dip CB, Whatley SD, Elder GH. Porphyrins and disorders of porphyrin metabolism. In: Burtis CA, Ashwood ER, Bruns DE, editors. Tietz textbook of clinical chemistry and molecular diagnostics, 4th ed. St. Louis: Elsevier Saunders, 2006:1209-35.
5. Nordmann Y, Puy H. Human hereditary hepatic porphyrias. Clin Chim Acta 2002;305:17-37.
6. Lim CK, Peters TJ. Urine and fecal porphyrin profiles by reversed-phase high-performance liquid chromatography in the porphyrias. Clin Chim Acta 1984;139:55-63.
7. Hindmarsh JT, Oliveras L, Greenway DC. Plasma porphyrins in the porphyrias. Clin Chem 1999;45:1070-6.
8. Schreiber WE, Raisys VA, Labbe RF. Liquid-chromatographic profiles of urinary porphyrins. Clin Chem 1983;29:527-30.
9. Richard MJ, Fovet B, Fontaine M, Boersma A. Analysis of free porphyrins in biological samples by high performance liquid chromatography. Ann Biol Clin 1986;44:639-44.
10. Beukeveld GJ, Wolthers BG, van Saene JJ, de Haan TH, de Ruyter-Buitenhuis LW, van Saene RH. Patterns of porphyrins excretion in feces as determined by liquid chromatography; reference values and the effect of flora suppression. Clin Chem 1987;33:2164-70.
11. Lockwood WH, Poulos V, Rossi E, Curnow DH. Rapid procedure for fecal porphyrin assay. Clin Chem 1985;31:1163-7.
12. Lai CK, Lam CW, Chan YW. High-performance thin-layer chromatography of free porphyrins for diagnosis of porphyria. Clin Chem 1994;40:2026-9.
13. Ford RE, Ou CN, Ellefson RD. Liquid-chromatographic analysis for urinary porphyrins. Clin Chem 1981;27:397-401.
14. Meyer HD, Jacob K, Vogt W, Knedel M. Diagnosis of porphyrias by ion-pair high-performance liquid chromatography. J Chromatogr 1980;199:339-43.
15. Johnson PM, Perkins SL, Kennedy SW. A high speed liquid-chromatographic method for measuring urine porphyrins. Clin Chem 1988;34:103-5.
16. To-Figueras J, Ozalla D, Herrero Mateu C. Long-standing changes in the urinary profile of porphyrin isomers after clinical remission of porphyria cutanea tarda. Ann Clin Lab Sci 2003;33:251-6.
17. Hindmarsh JT, Oliveras L, Greenway DC. Biochemical differentiation of the porphyrias. Clin Biochem 1999;32:609-19.
18. Chromolith columns general information and applications sheet note S.00000.1604, Darmstadt, Germany: Merck.
19. Sobel C, Cano C, Thiers RE. Separation and quantitation of coproporphyrin and uroporphyrin in urine. Clin Chem 1974;20:1397-402.
20. Rimington C. Spectral absorption coefficients of some porphyrins in the Soret-band region. Biochem J 1960;75:620-3.
21. Gunter EW, Turner WE, Huff DL. Investigation of protoporphyrin IX standard materials used in acid-extraction methods and a proposed correction for millimolar absorptivity of protoporphyrin IX. Clin Chem 1989;35:1601-8.
22. Lim CK, Rideout JM, Wright DJ. Separation of porphyrin isomers by high-performance liquid chromatography. Biochem J 1983;211:435-8.
23. Blake D, McManus J, Cronin V, Ratnaike S. Fecal coproporphyrin isomers in hereditary coproporphyria. Clin Chem 1992;38:96-100.
24. Bozek P, Hutta M, Hrivnakova B. Rapid analysis of porphyrins at low ng/l and mg/l levels in human urine by a gradient liquid chromatography method using octadecylsilica monolithic columns. J Chromatogr A 2005;1084:24-32.
25. Hindmarsh JT. The porphyrias, appropriate test selection. Clin Chim Acta 2003;333:203-7.